Protein: FRYL
Protein furry homolog-like (ALL1-fused gene from chromosome 4p12 protein)

Gene: FRYL
Organism: Homo sapiens
Interactions: 66
UniProt ID: O94915

Gene Ontology (top 5):
GO:0000902 - cell morphogenesis
GO:0005938 - cell cortex
GO:0030427 - site of polarized growth
GO:0031175 - neuron projection development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

321894

1433B
14-3-3 protein beta/alpha

7

10

High-throughput

0.679

High

321941

HOME3
Homer protein homolog 3

5

1

High-throughput

0.660

High

321908

1433F
14-3-3 protein eta

5

10

High-throughput

0.654

High

321902

1433G
14-3-3 protein gamma

5

10

High-throughput

0.652

High

321906

1433Z
14-3-3 protein zeta/delta

4

10

High-throughput

0.630

High

321915

FRY
Protein furry homolog

2

1

High-throughput

0.628

High

321892

1433T
14-3-3 protein theta

4

10

High-throughput

0.619

High

321925

HOME1
Homer protein homolog 1

3

1

High-throughput

0.616

High

321914

NHRF3
Na(+)/H(+) exchange regulatory cofactor NHE-RF3

2

3

High-throughput

0.558

High

321912

NHRF2
Na(+)/H(+) exchange regulatory cofactor NHE-RF2

2

3

High-throughput

0.549

High

321903

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

2

1

High-throughput

0.521

High

321942

STK26
Serine/threonine-protein kinase 26

1

4

High-throughput

0.489

High

321901

RHOA
Transforming protein RhoA

1

2

High-throughput

0.479

High

321887

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.458

High

321934

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.458

High

321895

1433S
14-3-3 protein sigma

1

10

High-throughput

0.437

High

321896

GRK5
G protein-coupled receptor kinase 5

1

1

High-throughput

0.437

High

321898

PLK1
Serine/threonine-protein kinase PLK1

1

2

High-throughput

0.437

High

321899

RAC3
Ras-related C3 botulinum toxin substrate 3

1

2

High-throughput

0.437

High

321900

CDC42
Cell division control protein 42 homolog

1

2

High-throughput

0.437

High

321907

KIF23
Kinesin-like protein KIF23

1

1

High-throughput

0.437

High

321924

IQGA3
Ras GTPase-activating-like protein IQGAP3

1

0

High-throughput

0.426

High

321936

PACN1
Protein kinase C and casein kinase substrate in neurons protein 1

1

1

High-throughput

0.417

High

71048

PDZ1P
Putative PDZ domain-containing protein PDZK1P1

1

3

High-throughput

0.407

High

254691

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

1

High-throughput

0.407

High

262194

SCN2B
Sodium channel regulatory subunit beta-2

1

1

High-throughput

0.407

High

321891

TNR5
Tumor necrosis factor receptor superfamily member 5

1

1

High-throughput

0.407

High

321918

ANR22
Ankyrin repeat domain-containing protein 22

1

1

High-throughput

0.407

High

321922

CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2

1

1

High-throughput

0.407

High

321930

MAML1
Mastermind-like protein 1

1

1

High-throughput

0.407

High

321919

K0930
Uncharacterized protein KIAA0930

3

0

High-throughput

0.339

High

321910

FLNC
Filamin-C

2

0

High-throughput

0.328

High

321929

RN138
E3 ubiquitin-protein ligase RNF138

2

0

High-throughput

0.328

High

321905

1433E
14-3-3 protein epsilon

2

0

High-throughput

0.318

High

321886

PRR35
Proline-rich protein 35

2

0

High-throughput

0.316

High

321927

Q8IVT4
Hypothetical MGC50722

2

0

High-throughput

0.316

High

321935

PDC10
Programmed cell death protein 10

2

0

High-throughput

0.316

High

321940

DISC1
Disrupted in schizophrenia 1 protein

2

0

High-throughput

0.307

High

321897

NOTC1
Neurogenic locus notch homolog protein 1

1

0

High-throughput

0.289

High

321937

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

0

High-throughput

0.282

High

321885

SLU7
Pre-mRNA-splicing factor SLU7

1

0

High-throughput

0.279

Low

321893

ARI4A
AT-rich interactive domain-containing protein 4A

1

0

High-throughput

0.279

Low

321917

FA78B
Protein FAM78B

1

0

High-throughput

0.279

Low

321923

MARK2
Serine/threonine-protein kinase MARK2

1

0

High-throughput

0.279

Low

321926

CCD71
Coiled-coil domain-containing protein 71

1

0

High-throughput

0.279

Low

321933

PI51A
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha

1

0

High-throughput

0.279

Low

321944

POLH
DNA polymerase eta

1

0

High-throughput

0.279

Low

321945

TACC3
Transforming acidic coiled-coil-containing protein 3

1

0

High-throughput

0.279

Low

321913

BAK
Bcl-2 homologous antagonist/killer

1

0

High-throughput

0.269

Low

321938

PELI2
E3 ubiquitin-protein ligase pellino homolog 2

1

0

High-throughput

0.251

Low

292965

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

319256

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.249

Low

321904

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.249

Low

321909

SQSTM
Sequestosome-1

1

0

High-throughput

0.249

Low

321911

SLMAP
Sarcolemmal membrane-associated protein

1

0

High-throughput

0.249

Low

321920

LRC31
Leucine-rich repeat-containing protein 31

1

0

High-throughput

0.249

Low

321921

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

321928

NHLC2
NHL repeat-containing protein 2

1

0

High-throughput

0.249

Low

321931

ZUP1
Zinc finger-containing ubiquitin peptidase 1

1

0

High-throughput

0.249

Low

321932

MMS19
MMS19 nucleotide excision repair protein homolog

1

0

High-throughput

0.249

Low

321939

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

0

High-throughput

0.249

Low

321943

UBQL1
Ubiquilin-1

1

0

High-throughput

0.249

Low

321888

FPR1
fMet-Leu-Phe receptor

1

0

High-throughput

0.232

Low

321889

EPHA1
Ephrin type-A receptor 1

1

0

High-throughput

0.232

Low

321890

HEMH
Ferrochelatase, mitochondrial

1

0

High-throughput

0.232

Low

321916

FAXC
Failed axon connections homolog

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025