Protein: PWP1
Periodic tryptophan protein 1

Gene: PWP1
Organism: Saccharomyces cerevisiae S288C
Interactions: 208
UniProt ID: P21304

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005730 - nucleolus
GO:0005737 - cytoplasm
GO:0006364 - rRNA processing

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

637259

ACT
Actin

2

5

High-throughput

0.802

High

637269

UTP17
NET1-associated nuclear protein 1

2

13

High-throughput

0.802

High

637298

TYW1
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase

2

1

High-throughput

0.802

High

637170

DBP2
ATP-dependent RNA helicase DBP2

2

15

High-throughput

0.793

High

637250

PESC
Pescadillo homolog

2

2

High-throughput

0.793

High

637166

PWP1
Periodic tryptophan protein 1

2

19

Small-scale

0.768

High

637294

BRX1
Ribosome biogenesis protein BRX1

5

6

Small-scale

0.720

High

632525

DBP3
ATP-dependent RNA helicase DBP3

1

15

High-throughput

0.698

High

637218

TCPB
T-complex protein 1 subunit beta

1

20

High-throughput

0.691

High

637264

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

16

High-throughput

0.691

High

637293

NOP12
Nucleolar protein 12

4

20

High-throughput

0.691

High

392220

HSP82
ATP-dependent molecular chaperone HSP82

4

14

High-throughput

0.672

High

637202

EBP2
rRNA-processing protein EBP2

3

4

High-throughput

0.666

High

637222

NOC2
Nucleolar complex protein 2

3

2

High-throughput

0.666

High

637252

DBP6
ATP-dependent RNA helicase DBP6

1

20

High-throughput

0.665

High

637216

CIC1
Proteasome-interacting protein CIC1

3

5

High-throughput

0.658

High

637234

TCPH
T-complex protein 1 subunit eta

1

20

High-throughput

0.646

High

637238

TCPQ
T-complex protein 1 subunit theta

1

20

High-throughput

0.646

High

523047

HSP71
Heat shock protein SSA1

3

18

High-throughput

0.633

High

637205

RPF2
Ribosome biogenesis protein RPF2

3

2

Small-scale

0.633

High

585850

CSK21
Casein kinase II subunit alpha

2

14

High-throughput

0.628

High

637226

SSB2
Ribosome-associated molecular chaperone SSB2

3

20

High-throughput

0.624

High

637194

SMC1
Structural maintenance of chromosomes protein 1

2

3

High-throughput

0.621

High

637224

DPO5
rDNA transcriptional regulator POL5

2

5

High-throughput

0.621

High

637285

FKBP4
FK506-binding protein 4

2

3

High-throughput

0.621

High

553942

TCPA
T-complex protein 1 subunit alpha

1

20

High-throughput

0.618

High

637219

TCPG
T-complex protein 1 subunit gamma

1

20

High-throughput

0.618

High

637221

TCPZ
T-complex protein 1 subunit zeta

1

20

High-throughput

0.618

High

637227

TCPE
T-complex protein 1 subunit epsilon

1

20

High-throughput

0.618

High

637286

CORO
Coronin-like protein

1

16

High-throughput

0.618

High

380961

H2B1
Histone H2B.1

1

14

High-throughput

0.618

High

419592

H2A2
Histone H2A.2

1

9

High-throughput

0.618

High

637174

SPB4
ATP-dependent rRNA helicase SPB4

1

20

High-throughput

0.618

High

637189

NHP2
H/ACA ribonucleoprotein complex subunit NHP2

1

13

High-throughput

0.618

High

637198

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

3

High-throughput

0.618

High

637207

GBLP
Small ribosomal subunit protein RACK1

1

19

High-throughput

0.618

High

637208

MAK5
ATP-dependent RNA helicase MAK5

1

20

High-throughput

0.618

High

637240

RS12
Small ribosomal subunit protein eS12

1

3

High-throughput

0.618

High

637256

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

20

High-throughput

0.618

High

637277

DHR1
Probable ATP-dependent RNA helicase DHR1

1

14

High-throughput

0.618

High

637299

YTM1
Ribosome biogenesis protein YTM1

1

16

High-throughput

0.618

High

637307

DBP10
ATP-dependent RNA helicase DBP10

1

20

High-throughput

0.618

High

637281

RRP5
rRNA biogenesis protein RRP5

2

20

High-throughput

0.614

High

517891

SSBP1
Single-stranded nucleic acid-binding protein

2

11

High-throughput

0.611

High

637258

RL15B
Large ribosomal subunit protein eL15B

2

6

High-throughput

0.611

High

543802

SSB1
Ribosome-associated molecular chaperone SSB1

2

20

High-throughput

0.601

High

637213

ENP1
Essential nuclear protein 1

2

3

High-throughput

0.584

High

637268

NOG1
Nucleolar GTP-binding protein 1

2

10

High-throughput

0.584

High

637300

NOP53
Ribosome biogenesis protein NOP53

2

4

High-throughput

0.584

High

637303

RRP6
Exosome complex exonuclease RRP6

2

6

High-throughput

0.584

High

637220

TCPD
T-complex protein 1 subunit delta

1

20

High-throughput

0.578

High

637209

ISW1
ISWI chromatin-remodeling complex ATPase ISW1

1

20

High-throughput

0.575

High

637168

RPA2
DNA-directed RNA polymerase I subunit RPA135

2

5

High-throughput

0.571

High

637175

RL5
Large ribosomal subunit protein uL18

2

4

High-throughput

0.571

High

383518

RS17A
Small ribosomal subunit protein eS17A

1

3

High-throughput

0.553

High

503894

RL27B
Large ribosomal subunit protein eL27B

1

2

High-throughput

0.553

High

600979

RL8A
Large ribosomal subunit protein eL8A

1

13

High-throughput

0.553

High

637184

RL8B
Large ribosomal subunit protein eL8B

1

13

High-throughput

0.553

High

525909

HSP72
Heat shock protein SSA2

2

18

High-throughput

0.552

High

597034

BIP
Endoplasmic reticulum chaperone BiP

2

19

High-throughput

0.552

High

637178

GAR1
H/ACA ribonucleoprotein complex subunit GAR1

1

1

High-throughput

0.541

High

637231

RLP7
Ribosome biogenesis protein RLP7

1

6

High-throughput

0.541

High

637275

CTK1
CTD kinase subunit alpha

1

12

High-throughput

0.541

High

637290

BRE1
E3 ubiquitin-protein ligase BRE1

1

19

High-throughput

0.541

High

367892

ENO2
Enolase 2

2

5

High-throughput

0.537

High

449065

CALM
Calmodulin

1

1

High-throughput

0.536

High

477512

MYO1
Myosin-1

1

3

High-throughput

0.536

High

623766

MYO2
Myosin-2

1

7

High-throughput

0.536

High

637185

XPO1
Exportin-1

1

17

High-throughput

0.536

High

637187

KNS1
Dual specificity protein kinase KNS1

1

9

High-throughput

0.536

High

637188

MYO4
Myosin-4

1

7

High-throughput

0.536

High

637228

PRK1
Actin-regulating kinase PRK1

1

3

High-throughput

0.536

High

637263

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

1

5

High-throughput

0.536

High

637270

FRK1
Fatty acyl-CoA synthetase and RNA processing-associated kinase 1

1

12

High-throughput

0.536

High

637279

MYO5
Myosin-5

1

4

High-throughput

0.536

High

637292

BUD20
Bud site selection protein 20

1

2

High-throughput

0.536

High

637296

HRK1
Serine/threonine-protein kinase HRK1

1

4

High-throughput

0.536

High

637310

RRP12
Ribosomal RNA-processing protein 12

1

1

High-throughput

0.536

High

433446

RL26A
Large ribosomal subunit protein uL24A

2

5

High-throughput

0.533

High

637236

LOC1
60S ribosomal subunit assembly/export protein LOC1

1

0

High-throughput

0.518

High

637169

BUR1
Serine/threonine-protein kinase BUR1

1

10

High-throughput

0.515

High

637241

ASNS2
Asparagine synthetase [glutamine-hydrolyzing] 2

1

2

High-throughput

0.515

High

637253

GIS2
Zinc finger protein GIS2

1

6

High-throughput

0.515

High

637284

PDP3
NuA3 HAT complex component PDP3

1

2

High-throughput

0.515

High

603005

EST1
Telomere elongation protein EST1

1

0

High-throughput

0.513

High

637191

ALK2
Serine/threonine-protein kinase Haspin homolog ALK2

1

0

High-throughput

0.513

High

637203

SHE2
SWI5-dependent HO expression protein 2

1

0

High-throughput

0.513

High

637211

SHE3
SWI5-dependent HO expression protein 3

1

0

High-throughput

0.513

High

637251

UTP8
U3 small nucleolar RNA-associated protein 8

1

0

High-throughput

0.513

High

637254

ELOA1
Elongin-A

1

0

High-throughput

0.513

High

637276

MUS81
Crossover junction endonuclease MUS81

1

0

High-throughput

0.513

High

637282

RGC1
Regulator of the glycerol channel 1

1

0

High-throughput

0.513

High

637291

NOP6
Nucleolar protein 6

1

0

High-throughput

0.513

High

367693

ENO1
Enolase 1

1

5

High-throughput

0.500

High

590527

HSP26
Heat shock protein 26

1

6

High-throughput

0.500

High

637197

PRS6B
26S proteasome regulatory subunit 6B homolog

1

13

High-throughput

0.500

High

637243

RIR4
Ribonucleoside-diphosphate reductase small chain 2

1

4

High-throughput

0.500

High

637190

SPT16
FACT complex subunit SPT16

1

8

High-throughput

0.494

High

453246

QCR2
Cytochrome b-c1 complex subunit 2, mitochondrial

1

1

High-throughput

0.489

High

562940

CAPZB
F-actin-capping protein subunit beta

1

4

High-throughput

0.489

High

598306

HEMH
Ferrochelatase, mitochondrial

1

1

High-throughput

0.489

High

637179

CAPZA
F-actin-capping protein subunit alpha

1

2

High-throughput

0.489

High

637262

AP1M1
AP-1 complex subunit mu-1-I

1

2

High-throughput

0.489

High

637272

PKH3
Serine/threonine-protein kinase PKH3

1

8

High-throughput

0.489

High

637312

RS22B
Small ribosomal subunit protein uS8B

1

3

High-throughput

0.489

High

149581

RS9A
Small ribosomal subunit protein uS4A

1

6

High-throughput

0.479

High

432487

RL7A
Large ribosomal subunit protein uL30A

1

6

High-throughput

0.479

High

433145

RL17A
Large ribosomal subunit protein uL22A

1

5

High-throughput

0.479

High

434822

RS3
Small ribosomal subunit protein uS3

1

5

High-throughput

0.479

High

435772

RS13
Small ribosomal subunit protein uS15

1

4

High-throughput

0.479

High

436317

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

7

High-throughput

0.479

High

441702

RS14A
Small ribosomal subunit protein uS11A

1

5

High-throughput

0.479

High

512254

RS6A
Small ribosomal subunit protein eS6A

1

3

High-throughput

0.479

High

514456

RS18A
Small ribosomal subunit protein uS13A

1

3

High-throughput

0.479

High

569905

RL3
Large ribosomal subunit protein uL3

1

5

High-throughput

0.479

High

578836

HSC82
ATP-dependent molecular chaperone HSC82

1

14

High-throughput

0.479

High

594182

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

4

High-throughput

0.479

High

637167

DPOE
DNA polymerase epsilon catalytic subunit A

1

3

High-throughput

0.479

High

637171

SIS1
Protein SIS1

1

15

High-throughput

0.479

High

637173

RS2
Small ribosomal subunit protein uS5

1

4

High-throughput

0.479

High

637176

RL16A
Large ribosomal subunit protein uL13A

1

5

High-throughput

0.479

High

637177

RS7A
Small ribosomal subunit protein eS7A

1

4

High-throughput

0.479

High

637181

TF2B
Transcription initiation factor IIB

1

6

High-throughput

0.479

High

637182

TF3B
Transcription factor IIIB 70 kDa subunit

1

6

High-throughput

0.479

High

637183

BMH1
Protein BMH1

1

7

High-throughput

0.479

High

637186

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

High-throughput

0.479

High

637192

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

11

High-throughput

0.479

High

637195

SMY2
Protein SMY2

1

1

High-throughput

0.479

High

637196

MRT4
Ribosome assembly factor MRT4

1

10

High-throughput

0.479

High

637201

RS27A
Small ribosomal subunit protein eS27A

1

2

High-throughput

0.479

High

637204

RL14A
Large ribosomal subunit protein eL14A

1

6

High-throughput

0.479

High

637206

NOP4
Nucleolar protein 4

1

13

High-throughput

0.479

High

637212

AIM4
Altered inheritance of mitochondria protein 4

1

1

High-throughput

0.479

High

637214

RS20
Small ribosomal subunit protein uS10

1

2

High-throughput

0.479

High

637215

RL14B
Large ribosomal subunit protein eL14B

1

6

High-throughput

0.479

High

637217

SSF1
Ribosome biogenesis protein SSF1

1

1

Small-scale

0.479

High

637223

EXO1
Exodeoxyribonuclease 1

1

1

High-throughput

0.479

High

637230

DSN1
Kinetochore-associated protein DSN1

1

1

High-throughput

0.479

High

637232

RL10
Large ribosomal subunit protein uL16

1

4

High-throughput

0.479

High

637235

UTP10
U3 small nucleolar RNA-associated protein 10

1

4

High-throughput

0.479

High

637239

MOG1
Nuclear import protein MOG1

1

1

High-throughput

0.479

High

637247

LSG1
Large subunit GTPase 1

1

14

Small-scale

0.479

High

637257

NOP15
Ribosome biogenesis protein 15

1

16

High-throughput

0.479

High

637265

RS15
Small ribosomal subunit protein uS19

1

3

High-throughput

0.479

High

637267

XRN2
5'-3' exoribonuclease 2

1

6

High-throughput

0.479

High

637274

ARX1
Probable metalloprotease ARX1

1

3

Small-scale

0.479

High

637278

VMS1
tRNA endonuclease VMS1

1

2

High-throughput

0.479

High

637280

UTP14
U3 small nucleolar RNA-associated protein 14

1

6

High-throughput

0.479

High

637283

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.479

High

637287

NOC4
Nucleolar complex protein 4

1

8

High-throughput

0.479

High

637288

URN1
Pre-mRNA-splicing factor URN1

1

1

High-throughput

0.479

High

637301

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

2

High-throughput

0.479

High

637304

YRA1
RNA annealing protein YRA1

1

12

High-throughput

0.479

High

637305

MAK21
Ribosome biogenesis protein MAK21

1

8

High-throughput

0.479

High

637308

NOP58
Nucleolar protein 58

1

10

High-throughput

0.479

High

637311

RL11B
Large ribosomal subunit protein uL5B

1

4

High-throughput

0.479

High

637172

RRP43
Exosome complex component RRP43

1

0

High-throughput

0.458

High

637210

RRN10
RNA polymerase I-specific transcription initiation factor RRN10

1

0

High-throughput

0.458

High

637271

ESP1
Separin

1

0

High-throughput

0.458

High

637273

BUL2
Ubiquitin ligase-binding protein BUL2

1

0

Small-scale

0.458

High

637289

VIP1
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase

1

0

High-throughput

0.458

High

637295

SGO1
Shugoshin

1

0

High-throughput

0.458

High

366926

ATPB
ATP synthase subunit beta, mitochondrial

1

6

High-throughput

0.457

High

425104

OTC
Ornithine carbamoyltransferase

1

4

High-throughput

0.457

High

637180

IDH1
Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial

1

7

High-throughput

0.457

High

394235

EF1A
Elongation factor 1-alpha

1

3

High-throughput

0.445

High

427137

RLA0
Large ribosomal subunit protein uL10

1

10

High-throughput

0.445

High

453419

PYR1
Multifunctional protein URA2

1

7

High-throughput

0.445

High

486026

TBA1
Tubulin alpha-1 chain

1

16

High-throughput

0.445

High

510187

HSP77
Import motor subunit, mitochondrial

1

20

High-throughput

0.445

High

592010

VATB
V-type proton ATPase subunit B

1

7

High-throughput

0.445

High

637199

HSP78
Heat shock protein 78, mitochondrial

1

4

High-throughput

0.445

High

637225

IMB4
Importin subunit beta-4

1

9

High-throughput

0.445

High

637244

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

4

High-throughput

0.445

High

637246

CWC23
Pre-mRNA-splicing factor CWC23

1

15

High-throughput

0.445

High

637255

JJJ1
J protein JJJ1

1

18

High-throughput

0.445

High

637261

SEN1
Helicase SEN1

1

11

Small-scale

0.445

High

154134

RL36B
Large ribosomal subunit protein eL36B

1

3

High-throughput

0.437

High

409934

RL25
Large ribosomal subunit protein uL23

1

4

High-throughput

0.437

High

432798

RL9A
Large ribosomal subunit protein uL6A

1

5

High-throughput

0.437

High

432975

RL6B
Large ribosomal subunit protein eL6B

1

4

High-throughput

0.437

High

434132

RL36A
Large ribosomal subunit protein eL36A

1

3

High-throughput

0.437

High

434320

RL15A
Large ribosomal subunit protein eL15A

1

6

High-throughput

0.437

High

434515

RL22A
Large ribosomal subunit protein eL22A

1

4

High-throughput

0.437

High

454874

RS19A
Small ribosomal subunit protein eS19A

1

4

High-throughput

0.437

High

502848

RS22A
Small ribosomal subunit protein uS8A

1

3

High-throughput

0.437

High

504037

RL31A
Large ribosomal subunit protein eL31A

1

4

High-throughput

0.437

High

511135

RL20B
Large ribosomal subunit protein eL20B

1

4

High-throughput

0.437

High

511371

RL43B
Large ribosomal subunit protein eL43B

1

4

High-throughput

0.437

High

512818

RS8A
Small ribosomal subunit protein eS8A

1

4

High-throughput

0.437

High

513627

RL2A
Large ribosomal subunit protein uL2A

1

4

High-throughput

0.437

High

515207

RL35A
Large ribosomal subunit protein uL29A

1

2

High-throughput

0.437

High

637193

RSSA1
Small ribosomal subunit protein uS2A

1

4

High-throughput

0.437

High

637200

RS3A1
Small ribosomal subunit protein eS1A

1

3

High-throughput

0.437

High

637229

RL34B
Large ribosomal subunit protein eL34B

1

4

High-throughput

0.437

High

637237

RL17B
Large ribosomal subunit protein uL22B

1

5

High-throughput

0.437

High

637242

RL37A
Large ribosomal subunit protein eL37A

1

1

High-throughput

0.437

High

637245

RL37B
Large ribosomal subunit protein eL37B

1

1

High-throughput

0.437

High

637248

RL26B
Large ribosomal subunit protein uL24B

1

5

High-throughput

0.437

High

637249

EIF2A
Eukaryotic translation initiation factor 2A

1

6

High-throughput

0.437

High

637260

RL34A
Large ribosomal subunit protein eL34A

1

4

High-throughput

0.437

High

637266

RL21A
Large ribosomal subunit protein eL21A

1

2

High-throughput

0.437

High

637297

RS10A
Small ribosomal subunit protein eS10A

1

8

High-throughput

0.437

High

637302

ATG9
Autophagy-related protein 9

1

1

High-throughput

0.437

High

637309

RL21B
Large ribosomal subunit protein eL21B

1

2

High-throughput

0.437

High

637233

ZIM17
Mitochondrial protein import protein ZIM17

1

0

High-throughput

0.249

Low

637306

JID1
J domain-containing protein 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025