Protein: LZTR1
Leucine-zipper-like transcriptional regulator 1 (LZTR-1)

Gene: LZTR1
Organism: Homo sapiens
Interactions: 103
UniProt ID: Q8N653

Gene Ontology (top 5):
GO:0005794 - Golgi apparatus
GO:0012505 - endomembrane system
GO:0016567 - protein ubiquitination
GO:0031267 - small GTPase binding
GO:0031463 - Cul3-RING ubiquitin ligase complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1235436

LZTR1
Leucine-zipper-like transcriptional regulator 1

5

18

Small-scale

0.917

High

1042036

CUL3
Cullin-3

5

20

Small-scale

0.915

High

349482

RASH
GTPase HRas

6

7

Small-scale

0.731

High

1235461

KBTB4
Kelch repeat and BTB domain-containing protein 4

2

19

High-throughput

0.726

High

348788

RASN
GTPase NRas

5

8

Small-scale

0.704

High

350348

RASK
GTPase KRas

6

8

Small-scale

0.669

High

1235451

RIT2
GTP-binding protein Rit2

3

9

High-throughput

0.662

High

1235471

ZBTB1
Zinc finger and BTB domain-containing protein 1

1

2

High-throughput

0.625

High

1235444

RIT1
GTP-binding protein Rit1

3

9

Small-scale

0.621

High

1043103

CUL4A
Cullin-4A

1

20

High-throughput

0.618

High

209115

NCK2
Cytoplasmic protein NCK2

3

5

High-throughput

0.609

High

796423

PTN9
Tyrosine-protein phosphatase non-receptor type 9

3

1

High-throughput

0.609

High

1235452

NUD12
NAD-capped RNA hydrolase NUDT12

3

7

High-throughput

0.609

High

891221

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

2

15

High-throughput

0.606

High

374533

RAF1
RAF proto-oncogene serine/threonine-protein kinase

2

9

Small-scale

0.584

High

1235464

GCP4
Gamma-tubulin complex component 4

2

1

High-throughput

0.584

High

225891

KPRB
Phosphoribosyl pyrophosphate synthase-associated protein 2

2

6

High-throughput

0.574

High

757685

IF4A3
Eukaryotic initiation factor 4A-III

2

10

High-throughput

0.574

High

1235455

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

2

13

High-throughput

0.574

High

1235456

NUAK2
NUAK family SNF1-like kinase 2

2

2

High-throughput

0.574

High

253751

AUXI
Auxilin

2

1

High-throughput

0.558

High

156098

RASM
Ras-related protein M-Ras

2

9

Small-scale

0.543

High

1235442

ASB12
Ankyrin repeat and SOCS box protein 12

1

4

High-throughput

0.541

High

1235457

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

1

3

High-throughput

0.541

High

568995

CAN2
Calpain-2 catalytic subunit

1

1

High-throughput

0.536

High

1168481

TRI72
Tripartite motif-containing protein 72

1

4

High-throughput

0.536

High

1235440

PAR3L
Partitioning defective 3 homolog B

1

6

High-throughput

0.536

High

206633

MED7
Mediator of RNA polymerase II transcription subunit 7

1

0

High-throughput

0.518

High

1074841

TAF11
Transcription initiation factor TFIID subunit 11

1

0

High-throughput

0.518

High

48063

E2F8
Transcription factor E2F8

1

3

High-throughput

0.494

High

455656

PARP1
Poly [ADP-ribose] polymerase 1

1

4

High-throughput

0.494

High

536581

HCLS1
Hematopoietic lineage cell-specific protein

1

3

High-throughput

0.494

High

617330

SP100
Nuclear autoantigen Sp-100

1

3

High-throughput

0.494

High

627303

MCM3
DNA replication licensing factor MCM3

1

10

High-throughput

0.494

High

676939

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

1

High-throughput

0.494

High

786392

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

1

High-throughput

0.494

High

880779

HDAC4
Histone deacetylase 4

1

5

High-throughput

0.494

High

977264

CEBPZ
CCAAT/enhancer-binding protein zeta

1

1

High-throughput

0.494

High

1016083

SRBP2
Sterol regulatory element-binding protein 2

1

5

High-throughput

0.494

High

1024489

CAF1A
Chromatin assembly factor 1 subunit A

1

3

High-throughput

0.494

High

1025263

NR1H3
Oxysterols receptor LXR-alpha

1

12

High-throughput

0.494

High

1027954

TBX2
T-box transcription factor TBX2

1

2

High-throughput

0.494

High

1191014

RAI1
Retinoic acid-induced protein 1

1

11

High-throughput

0.494

High

1223159

ZZZ3
ZZ-type zinc finger-containing protein 3

1

3

High-throughput

0.494

High

1235437

ANR53
Ankyrin repeat domain-containing protein 53

1

3

High-throughput

0.494

High

1235438

KDM2B
Lysine-specific demethylase 2B

1

13

High-throughput

0.494

High

1235439

FANK1
Fibronectin type 3 and ankyrin repeat domains protein 1

1

6

High-throughput

0.494

High

1235443

AP2B
Transcription factor AP-2-beta

1

2

High-throughput

0.494

High

1235446

SCMH1
Polycomb protein SCMH1

1

1

High-throughput

0.494

High

1235447

LMBL3
Lethal(3)malignant brain tumor-like protein 3

1

1

High-throughput

0.494

High

1235448

CNO6L
CCR4-NOT transcription complex subunit 6-like

1

4

High-throughput

0.494

High

1235454

TRIM5
Tripartite motif-containing protein 5

1

4

High-throughput

0.494

High

1235458

EHMT1
Histone-lysine N-methyltransferase EHMT1

1

8

High-throughput

0.494

High

1235459

RPA2
DNA-directed RNA polymerase I subunit RPA2

1

1

High-throughput

0.494

High

1235462

AATF
Protein AATF

1

1

High-throughput

0.494

High

1235463

RERE
Arginine-glutamic acid dipeptide repeats protein

1

9

High-throughput

0.494

High

1235470

RUVB1
RuvB-like 1

1

4

High-throughput

0.494

High

1235474

ZN451
E3 SUMO-protein ligase ZNF451

1

1

High-throughput

0.494

High

1235476

NEMO
NF-kappa-B essential modulator

1

14

High-throughput

0.494

High

417090

KCRM
Creatine kinase M-type

1

1

High-throughput

0.489

High

506246

PYGM
Glycogen phosphorylase, muscle form

1

1

High-throughput

0.489

High

522559

MYH1
Myosin-1

1

9

High-throughput

0.489

High

522627

MYH7
Myosin-7

1

9

High-throughput

0.489

High

528383

MYH6
Myosin-6

1

9

High-throughput

0.489

High

528416

MYH8
Myosin-8

1

9

High-throughput

0.489

High

993275

ACTN3
Alpha-actinin-3

1

1

High-throughput

0.489

High

1224678

WDFY3
WD repeat and FYVE domain-containing protein 3

1

4

High-throughput

0.489

High

1235445

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

3

High-throughput

0.489

High

1235465

MYH13
Myosin-13

1

9

High-throughput

0.489

High

1235475

MYH4
Myosin-4

1

9

High-throughput

0.489

High

598498

NF1
Neurofibromin

1

3

High-throughput

0.479

High

1159504

SCYL2
SCY1-like protein 2

1

4

Small-scale

0.479

High

1201994

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

5

Small-scale

0.479

High

170104

PLS1
Phospholipid scramblase 1

1

0

Small-scale

0.458

High

124629

CLIC1
Chloride intracellular channel protein 1

1

1

Small-scale

0.437

High

495570

THIO
Thioredoxin

1

2

Small-scale

0.437

High

519231

KCRB
Creatine kinase B-type

1

1

Small-scale

0.437

High

640542

DDX6
Probable ATP-dependent RNA helicase DDX6

1

9

Small-scale

0.437

High

814992

LEG7
Galectin-7

1

1

High-throughput

0.437

High

816260

LIMS1
LIM and senescent cell antigen-like-containing domain protein 1

1

4

Small-scale

0.437

High

906534

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

7

Small-scale

0.437

High

1067050

BRD3
Bromodomain-containing protein 3

1

11

High-throughput

0.437

High

1085822

IF16
Gamma-interferon-inducible protein 16

1

2

High-throughput

0.437

High

1235460

VTA1
Vacuolar protein sorting-associated protein VTA1 homolog

1

1

Small-scale

0.437

High

1235467

VPS4A
Vacuolar protein sorting-associated protein 4A

1

3

Small-scale

0.437

High

1235468

SHOC2
Leucine-rich repeat protein SHOC-2

1

5

Small-scale

0.437

High

478740

PNM6A
Paraneoplastic antigen-like protein 6A

1

1

High-throughput

0.407

High

1235450

AIFM3
Apoptosis-inducing factor 3

2

0

High-throughput

0.328

High

224682

SSX4
Protein SSX4

1

0

High-throughput

0.282

High

486931

MYBB
Myb-related protein B

1

0

High-throughput

0.282

High

583748

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

0

High-throughput

0.282

High

1182992

SND1
Staphylococcal nuclease domain-containing protein 1

1

0

High-throughput

0.282

High

1217396

ZN584
Zinc finger protein 584

1

0

High-throughput

0.282

High

1220017

SUGP2
SURP and G-patch domain-containing protein 2

1

0

High-throughput

0.282

High

1235449

ZN714
Zinc finger protein 714

1

0

High-throughput

0.282

High

1235453

PAPOG
Poly(A) polymerase gamma

1

0

High-throughput

0.282

High

1235466

ZN490
Zinc finger protein 490

1

0

High-throughput

0.282

High

1235469

TCF19
Transcription factor 19

1

0

High-throughput

0.282

High

1235472

MED16
Mediator of RNA polymerase II transcription subunit 16

1

0

High-throughput

0.282

High

1235473

ZN175
Zinc finger protein 175

1

0

High-throughput

0.282

High

1185544

CHM1B
Charged multivesicular body protein 1b

1

0

Small-scale

0.249

Low

1235441

CTL1
Choline transporter-like protein 1

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024