Protein: PTCD1
Pentatricopeptide repeat-containing protein 1, mitochondrial

Gene: PTCD1
Organism: Homo sapiens
Interactions: 131
UniProt ID: O75127

Gene Ontology (top 5):
GO:0000049 - tRNA binding
GO:0003723 - RNA binding
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0032543 - mitochondrial translation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

271013

ROA1
Heterogeneous nuclear ribonucleoprotein A1

5

1

Small-scale

0.712

High

271021

RBMX
RNA-binding motif protein, X chromosome

3

1

High-throughput

0.667

High

271044

TRA2A
Transformer-2 protein homolog alpha

3

2

High-throughput

0.667

High

271095

RM04
Large ribosomal subunit protein uL4m

3

0

High-throughput

0.638

High

271107

RM39
Large ribosomal subunit protein mL39

3

0

High-throughput

0.638

High

271074

RM50
Large ribosomal subunit protein mL50

2

1

High-throughput

0.628

High

271103

DDX28
Probable ATP-dependent RNA helicase DDX28

2

2

High-throughput

0.628

High

271108

FAKD2
FAST kinase domain-containing protein 2, mitochondrial

2

4

High-throughput

0.628

High

271041

ILF2
Interleukin enhancer-binding factor 2

2

1

High-throughput

0.611

High

271065

LN28B
Protein lin-28 homolog B

2

3

High-throughput

0.611

High

271099

LN28A
Protein lin-28 homolog A

2

3

High-throughput

0.611

High

271029

YBOX1
Y-box-binding protein 1

2

3

High-throughput

0.601

High

271032

SRSF3
Serine/arginine-rich splicing factor 3

2

4

High-throughput

0.601

High

271120

YBOX2
Y-box-binding protein 2

2

3

High-throughput

0.601

High

271038

RL6
Large ribosomal subunit protein eL6

2

0

High-throughput

0.585

High

134986

IF2B3
Insulin-like growth factor 2 mRNA-binding protein 3

2

0

High-throughput

0.576

High

271030

PRR3
Proline-rich protein 3

2

0

High-throughput

0.576

High

271055

RM51
Large ribosomal subunit protein mL51

2

0

High-throughput

0.576

High

271058

RM02
Large ribosomal subunit protein uL2m

2

0

High-throughput

0.576

High

271094

RM13
Large ribosomal subunit protein uL13m

2

0

High-throughput

0.576

High

271109

F120A
Constitutive coactivator of PPAR-gamma-like protein 1

2

0

High-throughput

0.576

High

271123

FKBP7
Peptidyl-prolyl cis-trans isomerase FKBP7

2

1

High-throughput

0.553

High

271061

MRM1
rRNA methyltransferase 1, mitochondrial

2

0

High-throughput

0.547

High

47934

RBM47
RNA-binding protein 47

1

1

High-throughput

0.536

High

61877

GTPBA
GTP-binding protein 10

1

1

High-throughput

0.536

High

214263

MSI1H
RNA-binding protein Musashi homolog 1

1

1

High-throughput

0.536

High

256556

HNRC1
Heterogeneous nuclear ribonucleoprotein C-like 1

1

1

High-throughput

0.536

High

271007

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

1

1

High-throughput

0.536

High

271011

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

3

High-throughput

0.536

High

271022

EFTS
Elongation factor Ts, mitochondrial

1

1

High-throughput

0.536

High

271023

IF2M
Translation initiation factor IF-2, mitochondrial

1

3

High-throughput

0.536

High

271035

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

1

High-throughput

0.536

High

271040

SRSF4
Serine/arginine-rich splicing factor 4

1

2

High-throughput

0.536

High

271042

SRSF5
Serine/arginine-rich splicing factor 5

1

3

High-throughput

0.536

High

271043

SRSF6
Serine/arginine-rich splicing factor 6

1

3

High-throughput

0.536

High

271045

ICT1
Large ribosomal subunit protein mL62

1

1

High-throughput

0.536

High

271052

RBMS2
RNA-binding motif, single-stranded-interacting protein 2

1

3

High-throughput

0.536

High

271053

SRSF7
Serine/arginine-rich splicing factor 7

1

2

High-throughput

0.536

High

271054

HNRL2
Heterogeneous nuclear ribonucleoprotein U-like protein 2

1

1

High-throughput

0.536

High

271057

SYAM
Alanine--tRNA ligase, mitochondrial

1

1

High-throughput

0.536

High

271062

ACSM5
Acyl-coenzyme A synthetase ACSM5, mitochondrial

1

1

High-throughput

0.536

High

271072

GUF1
Translation factor GUF1, mitochondrial

1

2

High-throughput

0.536

High

271080

RRF2M
Ribosome-releasing factor 2, mitochondrial

1

3

High-throughput

0.536

High

271082

RUSD4
Pseudouridylate synthase RPUSD4, mitochondrial

1

1

High-throughput

0.536

High

271083

PABP5
Polyadenylate-binding protein 5

1

1

High-throughput

0.536

High

271084

MTEF3
Transcription termination factor 3, mitochondrial

1

2

High-throughput

0.536

High

271087

RCC1L
RCC1-like G exchanging factor-like protein

1

1

High-throughput

0.536

High

271091

RBM42
RNA-binding protein 42

1

2

High-throughput

0.536

High

271096

PAIP1
Polyadenylate-binding protein-interacting protein 1

1

1

High-throughput

0.536

High

271100

NGRN
Neugrin

1

2

High-throughput

0.536

High

271115

ZN346
Zinc finger protein 346

1

1

High-throughput

0.536

High

271060

Q6ICH2
single-stranded DNA cytosine deaminase

2

2

High-throughput

0.533

High

271009

ESR1
Estrogen receptor

2

1

High-throughput

0.521

High

61368

VWA8
von Willebrand factor A domain-containing protein 8

1

0

High-throughput

0.513

High

192528

NUP42
Nucleoporin NUP42

1

0

High-throughput

0.513

High

271004

GATB
Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial

1

0

High-throughput

0.513

High

271018

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.513

High

271019

KAD4
Adenylate kinase 4, mitochondrial

1

0

High-throughput

0.513

High

271031

RT25
Small ribosomal subunit protein mS25

1

0

High-throughput

0.513

High

271036

MMSA
Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial

1

0

High-throughput

0.513

High

271039

FOLC
Folylpolyglutamate synthase, mitochondrial

1

0

High-throughput

0.513

High

271049

SYLM
Leucine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

271063

FAHD1
Oxaloacetate tautomerase FAHD1, mitochondrial

1

0

High-throughput

0.513

High

271067

ZCCHV
Zinc finger CCCH-type antiviral protein 1

1

0

High-throughput

0.513

High

271068

RM52
Large ribosomal subunit protein mL52

1

0

High-throughput

0.513

High

271069

FABD
Malonyl-CoA-acyl carrier protein transacylase, mitochondrial

1

0

High-throughput

0.513

High

271077

G45IP
Large ribosomal subunit protein mL64

1

0

High-throughput

0.513

High

271078

RM30
Large ribosomal subunit protein uL30m

1

0

High-throughput

0.513

High

271085

MASU1
Mitochondrial assembly of ribosomal large subunit protein 1

1

0

High-throughput

0.513

High

271090

UTP23
rRNA-processing protein UTP23 homolog

1

0

High-throughput

0.513

High

271097

GATA
Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial

1

0

High-throughput

0.513

High

271098

RM44
Large ribosomal subunit protein mL44

1

0

High-throughput

0.513

High

271104

RT18A
Large ribosomal subunit protein mL66

1

0

High-throughput

0.513

High

271112

AMACR
Alpha-methylacyl-CoA racemase

1

0

High-throughput

0.513

High

271113

MRM2
rRNA methyltransferase 2, mitochondrial

1

0

High-throughput

0.513

High

271117

ABT1
Activator of basal transcription 1

1

0

High-throughput

0.513

High

271118

RT17
Small ribosomal subunit protein uS17m

1

0

High-throughput

0.513

High

271119

RT07
Small ribosomal subunit protein uS7m

1

0

High-throughput

0.513

High

271121

SYYM
Tyrosine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

271122

RT18B
Small ribosomal subunit protein mS40

1

0

High-throughput

0.513

High

271124

RM42
Large ribosomal subunit protein mL42

1

0

High-throughput

0.513

High

271064

RBMS3
RNA-binding motif, single-stranded-interacting protein 3

1

3

High-throughput

0.489

High

271034

RBM3
RNA-binding protein 3

1

2

Small-scale

0.479

High

271079

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

240259

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

271016

CH60
60 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.458

High

271028

RL26
Large ribosomal subunit protein uL24

1

0

High-throughput

0.458

High

271051

PDK1
[Pyruvate dehydrogenase

1

0

High-throughput

0.458

High

271070

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.458

High

271092

TR61B
tRNA

1

0

High-throughput

0.458

High

271105

AKIP
Small ribosomal subunit protein mS38

1

0

High-throughput

0.458

High

271048

FAKD3
FAST kinase domain-containing protein 3, mitochondrial

1

4

Small-scale

0.445

High

271081

ABC3D
DNA dC->dU-editing enzyme APOBEC-3D

1

2

High-throughput

0.445

High

271005

RECQ4
ATP-dependent DNA helicase Q4

1

1

High-throughput

0.437

High

271008

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.437

High

271010

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.437

High

271026

MCM2
DNA replication licensing factor MCM2

1

1

High-throughput

0.437

High

271066

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

73357

B2CML4
single-stranded DNA cytosine deaminase

1

2

High-throughput

0.407

High

271114

FBW1B
F-box/WD repeat-containing protein 11

4

0

High-throughput

0.360

High

271071

ZC3H3
Zinc finger CCCH domain-containing protein 3

3

0

High-throughput

0.347

High

271024

CDX1
Homeobox protein CDX-1

2

0

High-throughput

0.328

High

271059

Z324B
Zinc finger protein 324B

2

0

High-throughput

0.328

High

271012

SYPH
Synaptophysin

2

0

High-throughput

0.316

High

271027

GEMI4
Gem-associated protein 4

2

0

High-throughput

0.316

High

271056

MTUS2
Microtubule-associated tumor suppressor candidate 2

2

0

High-throughput

0.316

High

271076

IKBD
NF-kappa-B inhibitor delta

2

0

High-throughput

0.316

High

271093

CAR10
Caspase recruitment domain-containing protein 10

2

0

High-throughput

0.316

High

271110

TFP11
Tuftelin-interacting protein 11

2

0

High-throughput

0.316

High

271020

DUS1
Dual specificity protein phosphatase 1

2

0

High-throughput

0.298

High

271017

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.282

High

271006

CBX6
Chromobox protein homolog 6

1

0

High-throughput

0.279

Low

271014

H2A1
Histone H2A type 1

1

0

High-throughput

0.279

Low

271015

GLI4
Zinc finger protein GLI4

1

0

High-throughput

0.279

Low

271033

SHC2
SHC-transforming protein 2

1

0

High-throughput

0.279

Low

271046

MAP7
Ensconsin

1

0

High-throughput

0.279

Low

271073

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.279

Low

271086

NEIL1
Endonuclease 8-like 1

1

0

High-throughput

0.279

Low

271088

RSLAB
Ras-like protein family member 10B

1

0

High-throughput

0.279

Low

271102

CT096
Uncharacterized protein C20orf96

1

0

High-throughput

0.279

Low

271111

ZBT47
Zinc finger and BTB domain-containing protein 47

1

0

High-throughput

0.279

Low

271116

ZN777
Zinc finger protein 777

1

0

High-throughput

0.279

Low

188627

BIRC5
Baculoviral IAP repeat-containing protein 5

1

0

Small-scale

0.249

Low

271025

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.249

Low

271037

H11
Histone H1.1

1

0

High-throughput

0.249

Low

271047

CUL7
Cullin-7

1

0

High-throughput

0.249

Low

271050

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.249

Low

271075

DEN6B
Protein DENND6B

1

0

High-throughput

0.249

Low

271089

RIOK1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.249

Low

271101

ANLN
Anillin

1

0

High-throughput

0.249

Low

271106

DJC28
DnaJ homolog subfamily C member 28

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025