Protein: ASPM
Abnormal spindle-like microcephaly-associated protein (Abnormal spindle protein homolog) (Asp homolog)

Gene: ASPM
Organism: Homo sapiens
Interactions: 156
UniProt ID: Q8IZT6

Gene Ontology (top 5):
GO:0000278 - mitotic cell cycle
GO:0001764 - neuron migration
GO:0002052 - positive regulation of neuroblast proliferation
GO:0005516 - calmodulin binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

501109

MLRV
Myosin regulatory light chain 2, ventricular/cardiac muscle isoform

2

20

High-throughput

0.811

High

1052558

RCN2
Reticulocalbin-2

2

20

Small-scale

0.694

High

50941

FSD2
Fibronectin type III and SPRY domain-containing protein 2

1

18

High-throughput

0.691

High

777218

PEX19
Peroxisomal biogenesis factor 19

3

4

High-throughput

0.667

High

1203489

SKAP1
Src kinase-associated phosphoprotein 1

3

20

High-throughput

0.667

High

1224770

DTBP1
Dysbindin

3

4

High-throughput

0.667

High

1224779

GCP5
Gamma-tubulin complex component 5

3

4

Small-scale

0.662

High

257197

PP6R2
Serine/threonine-protein phosphatase 6 regulatory subunit 2

2

6

High-throughput

0.628

High

1022940

CDC16
Cell division cycle protein 16 homolog

2

2

High-throughput

0.628

High

1152353

CNDH2
Condensin-2 complex subunit H2

2

1

High-throughput

0.628

High

1224759

FOXJ1
Forkhead box protein J1

2

5

High-throughput

0.628

High

1224766

MOAP1
Modulator of apoptosis 1

2

14

High-throughput

0.628

High

1224781

FEZ1
Fasciculation and elongation protein zeta-1

2

1

High-throughput

0.628

High

1224785

LZTS2
Leucine zipper putative tumor suppressor 2

2

20

High-throughput

0.628

High

1224816

NGN3
Neurogenin-3

2

7

High-throughput

0.628

High

1070859

RCN1
Reticulocalbin-1

1

4

High-throughput

0.618

High

932255

ACTC
Actin, alpha cardiac muscle 1

1

20

High-throughput

0.618

High

933271

TBA1B
Tubulin alpha-1B chain

1

5

High-throughput

0.618

High

1224799

TRI36
E3 ubiquitin-protein ligase TRIM36

1

20

High-throughput

0.618

High

515470

CDK4
Cyclin-dependent kinase 4

2

14

High-throughput

0.611

High

1042003

CUL3
Cullin-3

2

9

High-throughput

0.611

High

1192092

DNJB7
DnaJ homolog subfamily B member 7

2

4

High-throughput

0.611

High

1224762

T53I1
Tumor protein p53-inducible nuclear protein 1

2

0

High-throughput

0.602

High

1224797

CSN7B
COP9 signalosome complex subunit 7b

2

0

High-throughput

0.602

High

1085432

MK06
Mitogen-activated protein kinase 6

2

20

High-throughput

0.601

High

1224782

NP1L4
Nucleosome assembly protein 1-like 4

2

8

Small-scale

0.601

High

1224783

HAUS7
HAUS augmin-like complex subunit 7

2

0

High-throughput

0.585

High

387082

P53
Cellular tumor antigen p53

2

10

High-throughput

0.584

High

483950

CALM1
Calmodulin-1

1

19

High-throughput

0.575

High

484022

CALM2
Calmodulin-2

1

19

High-throughput

0.575

High

484165

CALM3
Calmodulin-3

1

19

High-throughput

0.575

High

614074

TBG1
Tubulin gamma-1 chain

1

6

Small-scale

0.575

High

1224784

TBA1C
Tubulin alpha-1C chain

1

5

High-throughput

0.575

High

702781

CADH5
Cadherin-5

2

13

High-throughput

0.574

High

1224761

CNKR1
Connector enhancer of kinase suppressor of ras 1

2

20

High-throughput

0.574

High

1224789

MAD3
Max dimerization protein 3

2

11

High-throughput

0.574

High

1224803

SYIM
Isoleucine--tRNA ligase, mitochondrial

2

2

High-throughput

0.574

High

1224804

DKK3
Dickkopf-related protein 3

2

6

High-throughput

0.574

High

1224817

EID1
EP300-interacting inhibitor of differentiation 1

2

2

High-throughput

0.574

High

160655

AURKA
Aurora kinase A

2

17

Small-scale

0.571

High

347296

MYC
Myc proto-oncogene protein

2

12

High-throughput

0.571

High

876842

NP1L1
Nucleosome assembly protein 1-like 1

2

8

Small-scale

0.571

High

983177

UBE3A
Ubiquitin-protein ligase E3A

1

5

Small-scale

0.552

High

1224788

KTNB1
Katanin p80 WD40 repeat-containing subunit B1

2

9

Small-scale

0.552

High

312322

IPO7
Importin-7

2

2

Small-scale

0.549

High

166000

PER2
Period circadian protein homolog 2

1

11

High-throughput

0.536

High

216760

CREB3
Cyclic AMP-responsive element-binding protein 3

1

3

High-throughput

0.536

High

364967

FRIL
Ferritin light chain

1

1

High-throughput

0.536

High

422542

CENPB
Major centromere autoantigen B

1

1

High-throughput

0.536

High

637942

PSA3
Proteasome subunit alpha type-3

1

1

High-throughput

0.536

High

714298

HSP74
Heat shock 70 kDa protein 4

1

4

High-throughput

0.536

High

787521

MTOR
Serine/threonine-protein kinase mTOR

1

6

High-throughput

0.536

High

796132

MAGA9
Melanoma-associated antigen 9

1

6

High-throughput

0.536

High

816258

LIMS1
LIM and senescent cell antigen-like-containing domain protein 1

1

15

High-throughput

0.536

High

1025170

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

1

7

High-throughput

0.536

High

1025653

EI2BE
Translation initiation factor eIF2B subunit epsilon

1

4

High-throughput

0.536

High

1032926

JIP2
C-Jun-amino-terminal kinase-interacting protein 2

1

2

High-throughput

0.536

High

1061165

NUMA1
Nuclear mitotic apparatus protein 1

1

18

High-throughput

0.536

High

1128061

CEP78
Centrosomal protein of 78 kDa

1

6

High-throughput

0.536

High

1224757

DNJB8
DnaJ homolog subfamily B member 8

1

4

High-throughput

0.536

High

1224763

TRI52
E3 ubiquitin-protein ligase TRIM52

1

13

High-throughput

0.536

High

1224773

ZN333
Zinc finger protein 333

1

2

High-throughput

0.536

High

1224775

LURA1
Leucine rich adaptor protein 1

1

3

High-throughput

0.536

High

418449

NPM
Nucleophosmin

1

3

High-throughput

0.515

High

538312

ENPL
Endoplasmin

1

8

High-throughput

0.515

High

653654

CALR
Calreticulin

1

2

High-throughput

0.515

High

886154

H2B1D
Histone H2B type 1-D

1

5

High-throughput

0.515

High

907095

PRS8
26S proteasome regulatory subunit 8

1

0

High-throughput

0.513

High

1055951

ZN460
Zinc finger protein 460

1

0

High-throughput

0.513

High

1224767

ENTR1
Endosome-associated-trafficking regulator 1

1

0

High-throughput

0.513

High

1224771

TET5A
Terminal nucleotidyltransferase 5A

1

0

High-throughput

0.513

High

1224780

CSRN1
Cysteine/serine-rich nuclear protein 1

1

0

High-throughput

0.513

High

1224810

INTU
Protein inturned

1

0

High-throughput

0.513

High

906015

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

16

Small-scale

0.501

High

1224760

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

13

High-throughput

0.501

High

216269

CALU
Calumenin

1

4

High-throughput

0.489

High

281017

KRT38
Keratin, type I cuticular Ha8

1

20

High-throughput

0.489

High

312803

M3K6
Mitogen-activated protein kinase kinase kinase 6

1

20

High-throughput

0.489

High

876652

ELL
RNA polymerase II elongation factor ELL

1

3

High-throughput

0.489

High

994502

QOR
Quinone oxidoreductase

1

1

High-throughput

0.489

High

1034489

OS9
Protein OS-9

1

3

High-throughput

0.489

High

1200390

ST32C
Serine/threonine-protein kinase 32C

1

13

High-throughput

0.489

High

1224758

ZCH10
Zinc finger CCHC domain-containing protein 10

1

2

High-throughput

0.489

High

1224776

ODAD1
Outer dynein arm-docking complex subunit 1

1

20

High-throughput

0.489

High

1224792

ANO3
Anoctamin-3

1

1

High-throughput

0.489

High

1224793

RSH6A
Radial spoke head protein 6 homolog A

1

7

High-throughput

0.489

High

1224809

PNMA2
Paraneoplastic antigen Ma2

1

14

High-throughput

0.489

High

155033

NDC80
Kinetochore protein NDC80 homolog

1

20

High-throughput

0.479

High

164420

TRI66
Tripartite motif-containing protein 66

1

12

High-throughput

0.479

High

175893

P73
Tumor protein p73

1

10

High-throughput

0.479

High

232931

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

6

High-throughput

0.479

High

258100

DNJB6
DnaJ homolog subfamily B member 6

1

3

High-throughput

0.479

High

319916

HERC2
E3 ubiquitin-protein ligase HERC2

1

7

High-throughput

0.479

High

374521

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

11

High-throughput

0.479

High

569869

CEBPB
CCAAT/enhancer-binding protein beta

1

6

High-throughput

0.479

High

880965

IF6
Eukaryotic translation initiation factor 6

1

1

High-throughput

0.479

High

963857

SET
Protein SET

1

6

High-throughput

0.479

High

969845

KIF23
Kinesin-like protein KIF23

1

17

High-throughput

0.479

High

1066380

KIF14
Kinesin-like protein KIF14

1

15

High-throughput

0.479

High

1224764

CLUA1
Clusterin-associated protein 1

1

1

High-throughput

0.479

High

1224769

GASP2
G-protein coupled receptor-associated sorting protein 2

1

2

High-throughput

0.479

High

1224787

THAP7
THAP domain-containing protein 7

1

1

High-throughput

0.479

High

1224794

P63
Tumor protein 63

1

10

High-throughput

0.479

High

1224795

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.479

High

1224796

ECT2
Protein ECT2

1

18

High-throughput

0.479

High

1224800

ANLN
Anillin

1

13

High-throughput

0.479

High

1224801

SMYD2
N-lysine methyltransferase SMYD2

1

3

High-throughput

0.479

High

1224802

HELLS
Lymphoid-specific helicase

1

4

High-throughput

0.479

High

1224805

DIC
Mitochondrial dicarboxylate carrier

1

2

High-throughput

0.479

High

1224808

TRIM1
Probable E3 ubiquitin-protein ligase MID2

1

20

Small-scale

0.479

High

1224812

FZR1
Fizzy-related protein homolog

1

9

High-throughput

0.479

High

836847

DNLI4
DNA ligase 4

1

0

High-throughput

0.460

High

1074366

STIL
SCL-interrupting locus protein

1

0

High-throughput

0.458

High

1085815

IF16
Gamma-interferon-inducible protein 16

1

0

High-throughput

0.458

High

56669

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

3

High-throughput

0.445

High

101741

F8W118
Nucleosome assembly protein 1 like 1

1

8

High-throughput

0.445

High

201958

WDR62
WD repeat-containing protein 62

1

3

Small-scale

0.445

High

265417

KTNA1
Katanin p60 ATPase-containing subunit A1

1

10

Small-scale

0.445

High

420854

H2B1J
Histone H2B type 1-J

1

5

Small-scale

0.445

High

672201

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

1

Small-scale

0.445

High

718008

BMI1
Polycomb complex protein BMI-1

1

14

High-throughput

0.445

High

875106

TERA
Transitional endoplasmic reticulum ATPase

1

3

Small-scale

0.445

High

1223604

KATL2
Katanin p60 ATPase-containing subunit A-like 2

1

10

High-throughput

0.445

High

1224768

GCP3
Gamma-tubulin complex component 3

1

4

Small-scale

0.445

High

1224777

IPO9
Importin-9

1

3

Small-scale

0.445

High

1224778

GCP6
Gamma-tubulin complex component 6

1

4

Small-scale

0.445

High

1224786

GCP2
Gamma-tubulin complex component 2

1

4

Small-scale

0.445

High

1224790

KIFC1
Kinesin-like protein KIFC1

1

2

Small-scale

0.445

High

1224806

GCP4
Gamma-tubulin complex component 4

1

4

Small-scale

0.445

High

1224813

CHIP
E3 ubiquitin-protein ligase CHIP

1

8

Small-scale

0.445

High

166276

GRRE1
Granule associated Rac and RHOG effector protein 1

1

1

High-throughput

0.437

High

279322

DNJB5
DnaJ homolog subfamily B member 5

1

2

High-throughput

0.437

High

530929

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

3

High-throughput

0.437

High

588788

DPA1
HLA class II histocompatibility antigen, DP alpha 1 chain

1

1

High-throughput

0.437

High

1159389

FBX42
F-box only protein 42

1

17

High-throughput

0.437

High

1224811

HECD1
E3 ubiquitin-protein ligase HECTD1

1

15

High-throughput

0.437

High

1224815

SSRG
Translocon-associated protein subunit gamma

1

1

High-throughput

0.437

High

116866

KIF2A
Kinesin-like protein KIF2A

1

0

Small-scale

0.426

High

278637

DCTN3
Dynactin subunit 3

1

0

Small-scale

0.426

High

1157514

MZT2B
Mitotic-spindle organizing protein 2B

1

0

Small-scale

0.426

High

72900

B4DLN1
cDNA FLJ60124, highly similar to Mitochondrial dicarboxylate carrier

1

2

High-throughput

0.407

High

87335

C9JA28
Translocon-associated protein subunit gamma

1

1

High-throughput

0.407

High

1224756

SPC24
Kinetochore protein Spc24

3

0

High-throughput

0.347

High

147622

TRAD1
TRAF-type zinc finger domain-containing protein 1

3

0

Small-scale

0.345

High

1224791

TX13A
Testis-expressed protein 13A

2

0

High-throughput

0.328

High

1224798

CRAC1
Cartilage acidic protein 1

2

0

High-throughput

0.328

High

1224807

GPN3
GPN-loop GTPase 3

2

0

High-throughput

0.318

High

942049

RPP38
Ribonuclease P protein subunit p38

1

0

High-throughput

0.279

Low

1110177

T10IP
Testis-specific protein 10-interacting protein

1

0

High-throughput

0.279

Low

1201962

PACS2
Phosphofurin acidic cluster sorting protein 2

1

0

High-throughput

0.279

Low

1218670

CCD83
Coiled-coil domain-containing protein 83

1

0

High-throughput

0.279

Low

1224765

ZUP1
Zinc finger-containing ubiquitin peptidase 1

1

0

Small-scale

0.249

Low

1224772

EAF1
ELL-associated factor 1

1

0

High-throughput

0.249

Low

1224814

SNX7
Sorting nexin-7

1

0

High-throughput

0.249

Low

1033089

PM2P3
Putative postmeiotic segregation increased 2-like protein 3

1

0

High-throughput

0.232

Low

1224774

C170L
Cep170-like protein

1

0

Small-scale

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024