Protein: CUED1
CUE domain-containing protein 1

Gene: CUED1, CUEDC1
Organism: Homo sapiens
Interactions: 113
UniProt ID: Q9NWM3

Gene Ontology (top 5):
GO:0043130 - ubiquitin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

508717

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

3

1

Small-scale

0.756

High

1256908

TM1L2
TOM1-like protein 2

3

3

High-throughput

0.662

High

256510

TOM1
Target of Myb1 membrane trafficking protein

3

3

Small-scale

0.650

High

1327845

ARRD1
Arrestin domain-containing protein 1

4

1

High-throughput

0.630

High

1437702

SMUF2
E3 ubiquitin-protein ligase SMURF2

4

8

Small-scale

0.630

High

683525

IKBA
NF-kappa-B inhibitor alpha

3

1

High-throughput

0.609

High

1155195

EREP1
Endosomal transmembrane epsin interactor 1

3

1

High-throughput

0.609

High

1384138

ARRD3
Arrestin domain-containing protein 3

3

1

High-throughput

0.604

High

861806

NEDD4
E3 ubiquitin-protein ligase NEDD4

2

8

High-throughput

0.602

High

243104

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.586

High

1209722

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

1

Small-scale

0.574

High

1420572

TRIM5
Tripartite motif-containing protein 5

2

1

High-throughput

0.574

High

982339

UB2D2
Ubiquitin-conjugating enzyme E2 D2

2

2

High-throughput

0.553

High

1397297

UB2E2
Ubiquitin-conjugating enzyme E2 E2

2

2

High-throughput

0.553

High

425646

ISG15
Ubiquitin-like protein ISG15

1

2

Small-scale

0.553

High

1400036

NED4L
E3 ubiquitin-protein ligase NEDD4-like

2

8

High-throughput

0.549

High

1010537

EREP3
Protein ENTREP3

2

1

High-throughput

0.549

High

1037924

HEN2
Helix-loop-helix protein 2

2

1

High-throughput

0.549

High

1394626

ITCH
E3 ubiquitin-protein ligase Itchy homolog

2

8

High-throughput

0.549

High

1430217

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

2

8

High-throughput

0.549

High

1447687

BIRC6
Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6

2

1

High-throughput

0.549

High

1451224

HECW2
E3 ubiquitin-protein ligase HECW2

2

8

High-throughput

0.549

High

290269

TM1L1
TOM1-like protein 1

1

3

High-throughput

0.536

High

1438985

SMUF1
E3 ubiquitin-protein ligase SMURF1

2

8

Small-scale

0.534

High

1451231

MFHA1
Malignant fibrous histiocytoma-amplified sequence 1

1

1

High-throughput

0.489

High

691862

MK03
Mitogen-activated protein kinase 3

1

1

High-throughput

0.489

High

703725

MK01
Mitogen-activated protein kinase 1

1

1

High-throughput

0.489

High

862498

YAP1
Transcriptional coactivator YAP1

1

7

High-throughput

0.489

High

883341

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

1

High-throughput

0.489

High

1448916

DUS22
Dual specificity protein phosphatase 22

1

1

High-throughput

0.489

High

1381208

UB2E3
Ubiquitin-conjugating enzyme E2 E3

1

2

High-throughput

0.439

High

1355904

DUS19
Dual specificity protein phosphatase 19

1

1

High-throughput

0.437

High

1420541

TRIM9
E3 ubiquitin-protein ligase TRIM9

1

1

High-throughput

0.437

High

132341

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

8

High-throughput

0.407

High

1177203

MICB
MHC class I polypeptide-related sequence B

1

1

High-throughput

0.407

High

1260712

HECW1
E3 ubiquitin-protein ligase HECW1

1

8

High-throughput

0.407

High

1451225

TRI10
Tripartite motif-containing protein 10

1

1

High-throughput

0.407

High

181023

LRAD4
Low-density lipoprotein receptor class A domain-containing protein 4

4

0

High-throughput

0.360

High

1334460

ZN114
Zinc finger protein 114

4

0

High-throughput

0.360

High

1451227

MYO6
Unconventional myosin-VI

4

0

High-throughput

0.360

High

217211

MS18B
Protein Mis18-beta

3

0

High-throughput

0.347

High

1250085

TMM92
Transmembrane protein 92

3

0

High-throughput

0.347

High

1451118

TMM51
Transmembrane protein 51

3

0

High-throughput

0.347

High

222216

NCK2
Cytoplasmic protein NCK2

2

0

High-throughput

0.316

High

1392066

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

2

0

High-throughput

0.316

High

1392935

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

0

High-throughput

0.316

High

1451223

ABI2
Abl interactor 2

2

0

High-throughput

0.316

High

771250

APJ
Apelin receptor

2

0

High-throughput

0.313

High

1257305

STXB4
Syntaxin-binding protein 4

2

0

High-throughput

0.313

High

1350283

URGCP
Up-regulator of cell proliferation

2

0

High-throughput

0.313

High

1358030

TM171
Transmembrane protein 171

2

0

High-throughput

0.313

High

397063

ESR1
Estrogen receptor

2

0

High-throughput

0.298

High

1451237

NEMO
NF-kappa-B essential modulator

1

0

High-throughput

0.292

High

943823

UBS3A
Ubiquitin-associated and SH3 domain-containing protein A

1

0

High-throughput

0.282

High

169151

ML12B
Myosin regulatory light chain 12B

1

0

High-throughput

0.279

Low

277417

TP4A3
Protein tyrosine phosphatase type IVA 3

1

0

High-throughput

0.279

Low

290762

SURF6
Surfeit locus protein 6

1

0

High-throughput

0.279

Low

301241

RL1D1
Ribosomal L1 domain-containing protein 1

1

0

High-throughput

0.279

Low

419236

H2A1B
Histone H2A type 1-B/E

1

0

High-throughput

0.279

Low

628849

TBP
TATA-box-binding protein

1

0

High-throughput

0.279

Low

860981

RS10
Small ribosomal subunit protein eS10

1

0

High-throughput

0.279

Low

960917

RL15
Large ribosomal subunit protein eL15

1

0

High-throughput

0.279

Low

972591

RS14
Small ribosomal subunit protein uS11

1

0

High-throughput

0.279

Low

1054799

SUH
Recombining binding protein suppressor of hairless

1

0

High-throughput

0.279

Low

1134176

NTCP
Hepatic sodium/bile acid cotransporter

1

0

High-throughput

0.279

Low

1195274

TM52B
Transmembrane protein 52B

1

0

High-throughput

0.279

Low

1206609

PLAC9
Placenta-specific protein 9

1

0

High-throughput

0.279

Low

1206688

LRC73
Leucine-rich repeat-containing protein 73

1

0

High-throughput

0.279

Low

1208198

P4R3B
Serine/threonine-protein phosphatase 4 regulatory subunit 3B

1

0

High-throughput

0.279

Low

1333818

RDH13
Retinol dehydrogenase 13

1

0

High-throughput

0.279

Low

1349563

RM30
Large ribosomal subunit protein uL30m

1

0

High-throughput

0.279

Low

1371973

VPP1
V-type proton ATPase 116 kDa subunit a 1

1

0

High-throughput

0.279

Low

1387976

RM38
Large ribosomal subunit protein mL38

1

0

High-throughput

0.279

Low

1388106

ERLEC
Endoplasmic reticulum lectin 1

1

0

High-throughput

0.279

Low

1446629

C1QR1
Complement component C1q receptor

1

0

High-throughput

0.279

Low

1450037

TXLNG
Gamma-taxilin

1

0

High-throughput

0.279

Low

1451229

MTMR6
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR6

1

0

High-throughput

0.279

Low

1451234

SPIN1
Spindlin-1

1

0

High-throughput

0.279

Low

1451236

TX264
Testis-expressed protein 264

1

0

High-throughput

0.279

Low

1089897

ILF3
Interleukin enhancer-binding factor 3

1

0

High-throughput

0.269

Low

1098850

M3K1
Mitogen-activated protein kinase kinase kinase 1

1

0

Small-scale

0.261

Low

1369908

OSTF1
Osteoclast-stimulating factor 1

1

0

High-throughput

0.251

Low

1381244

WBP2
WW domain-binding protein 2

1

0

Small-scale

0.251

Low

764451

CTNA1
Catenin alpha-1

1

0

High-throughput

0.249

Low

1451233

SRPRB
Signal recognition particle receptor subunit beta

1

0

High-throughput

0.249

Low

67182

ZAR1L
Protein ZAR1-like

1

0

High-throughput

0.232

Low

231817

MFS11
UNC93-like protein MFSD11

1

0

High-throughput

0.232

Low

1010116

DLK1
Protein delta homolog 1

1

0

High-throughput

0.232

Low

1082575

NEXN
Nexilin

1

0

High-throughput

0.232

Low

1126374

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

1

0

High-throughput

0.232

Low

1160829

MAPK3
MAP kinase-activated protein kinase 3

1

0

High-throughput

0.232

Low

1180972

HFE
Hereditary hemochromatosis protein

1

0

High-throughput

0.232

Low

1199042

KLH12
Kelch-like protein 12

1

0

High-throughput

0.232

Low

1244120

TMM88
Transmembrane protein 88

1

0

High-throughput

0.232

Low

1295582

MIB1
E3 ubiquitin-protein ligase MIB1

1

0

High-throughput

0.232

Low

1311179

UBR2
E3 ubiquitin-protein ligase UBR2

1

0

High-throughput

0.232

Low

1325093

PLCD3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3

1

0

High-throughput

0.232

Low

1331432

MB213
Protein mab-21-like 3

1

0

High-throughput

0.232

Low

1352580

G6PT3
Glucose-6-phosphate exchanger SLC37A2

1

0

High-throughput

0.232

Low

1381925

C102A
Coiled-coil domain-containing protein 102A

1

0

High-throughput

0.232

Low

1384225

LDAF1
Lipid droplet assembly factor 1

1

0

High-throughput

0.232

Low

1386840

KCD12
BTB/POZ domain-containing protein KCTD12

1

0

High-throughput

0.232

Low

1402257

WRIP1
ATPase WRNIP1

1

0

High-throughput

0.232

Low

1411253

MXRA8
Matrix remodeling-associated protein 8

1

0

High-throughput

0.232

Low

1415689

TR61B
tRNA

1

0

High-throughput

0.232

Low

1431264

DJC25
DnaJ homolog subfamily C member 25

1

0

High-throughput

0.232

Low

1447776

DBLOH
Diablo IAP-binding mitochondrial protein

1

0

High-throughput

0.232

Low

1450901

RNF12
E3 ubiquitin-protein ligase RLIM

1

0

High-throughput

0.232

Low

1451226

RABX5
Rab5 GDP/GTP exchange factor

1

0

High-throughput

0.232

Low

1451228

COR2B
Coronin-2B

1

0

High-throughput

0.232

Low

1451230

TCAF1
TRPM8 channel-associated factor 1

1

0

High-throughput

0.232

Low

1451232

PCDG6
Protocadherin gamma-A6

1

0

High-throughput

0.232

Low

1451235

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025