Protein: ELP3
Elongator complex protein 3 (hELP3) (EC 2.3.1.311) (tRNA uridine(34) acetyltransferase)

Gene: ELP3
Organism: Homo sapiens
Interactions: 95
UniProt ID: Q9H9T3

Gene Ontology (top 5):
GO:0000049 - tRNA binding
GO:0001764 - neuron migration
GO:0002098 - tRNA wobble uridine modification
GO:0002926 - tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

327650

ELP1
Elongator complex protein 1

9

4

Small-scale

0.974

High

1388683

ELP4
Elongator complex protein 4

4

1

Small-scale

0.881

High

1233265

ELP2
Elongator complex protein 2

3

4

Small-scale

0.861

High

302964

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

2

1

High-throughput

0.754

High

954613

PRPS1
Ribose-phosphate pyrophosphokinase 1

3

1

High-throughput

0.667

High

1110568

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

3

2

High-throughput

0.662

High

711670

3MG
DNA-3-methyladenine glycosylase

3

0

High-throughput

0.638

High

1389153

KTI12
Protein KTI12 homolog

2

1

Small-scale

0.621

High

1081195

ELP6
Elongator complex protein 6

2

1

Small-scale

0.619

High

239214

ZNRD2
Protein ZNRD2

2

0

High-throughput

0.602

High

1382750

ISOC2
Isochorismatase domain-containing protein 2

2

0

High-throughput

0.602

High

373180

MYC
Myc proto-oncogene protein

2

0

Small-scale

0.598

High

1380172

FBXW7
F-box/WD repeat-containing protein 7

1

0

High-throughput

0.586

High

561150

GILT
Gamma-interferon-inducible lysosomal thiol reductase

2

0

High-throughput

0.585

High

1408293

DUS9
Dual specificity protein phosphatase 9

2

0

High-throughput

0.585

High

242967

PRKN
E3 ubiquitin-protein ligase parkin

2

2

High-throughput

0.584

High

391467

FRIL
Ferritin light chain

2

0

High-throughput

0.576

High

1352074

ELP5
Elongator complex protein 5

2

0

Small-scale

0.576

High

1403576

MMS19
MMS19 nucleotide excision repair protein homolog

2

0

Small-scale

0.559

High

537929

HSP7C
Heat shock cognate 71 kDa protein

2

0

High-throughput

0.547

High

549688

PRPS2
Ribose-phosphate pyrophosphokinase 2

1

1

High-throughput

0.536

High

877239

KC1D
Casein kinase I isoform delta

1

2

High-throughput

0.536

High

1110300

KCC2B
Calcium/calmodulin-dependent protein kinase type II subunit beta

1

2

High-throughput

0.536

High

1277477

ZFY16
Zinc finger FYVE domain-containing protein 16

1

1

High-throughput

0.536

High

1402673

SMC6
Structural maintenance of chromosomes protein 6

1

1

High-throughput

0.536

High

1437274

SIR3
NAD-dependent protein deacetylase sirtuin-3, mitochondrial

1

1

High-throughput

0.536

High

1437279

TRAK1
Trafficking kinesin-binding protein 1

1

1

High-throughput

0.536

High

1437280

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

1

2

High-throughput

0.536

High

1352272

DCA11
DDB1- and CUL4-associated factor 11

1

0

High-throughput

0.517

High

831452

CCNF
Cyclin-F

1

1

High-throughput

0.515

High

144320

ACACB
Acetyl-CoA carboxylase 2

1

0

High-throughput

0.513

High

259119

DNJA2
DnaJ homolog subfamily A member 2

1

0

High-throughput

0.513

High

342039

CEP43
Centrosomal protein 43

1

0

High-throughput

0.513

High

354871

DNAL4
Dynein axonemal light chain 4

1

0

High-throughput

0.513

High

832579

ETV3
ETS translocation variant 3

1

0

High-throughput

0.513

High

848721

MAGA9
Melanoma-associated antigen 9

1

0

High-throughput

0.513

High

916707

PPP5
Serine/threonine-protein phosphatase 5

1

0

High-throughput

0.513

High

1054650

PSME1
Proteasome activator complex subunit 1

1

0

High-throughput

0.513

High

1144168

TEBP
Prostaglandin E synthase 3

1

0

High-throughput

0.513

High

1193129

PKHN1
Pleckstrin homology domain-containing family N member 1

1

0

High-throughput

0.513

High

1397246

LURA1
Leucine rich adaptor protein 1

1

0

High-throughput

0.513

High

1399532

IP6K3
Inositol hexakisphosphate kinase 3

1

0

High-throughput

0.513

High

1419184

NEUL
Neurolysin, mitochondrial

1

0

High-throughput

0.513

High

1420201

FOXP3
Forkhead box protein P3

1

0

High-throughput

0.513

High

1437272

PAR6A
Partitioning defective 6 homolog alpha

1

0

High-throughput

0.513

High

1437273

ANLN
Anillin

1

0

High-throughput

0.513

High

1258950

H32
Histone H3.2

1

2

Small-scale

0.501

High

1437278

AT7L1
Ataxin-7-like protein 1

1

1

High-throughput

0.489

High

980349

H4
Histone H4

1

0

Small-scale

0.480

High

1437283

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

0

Small-scale

0.480

High

316027

RECQ4
ATP-dependent DNA helicase Q4

1

1

High-throughput

0.479

High

604214

CXA1
Gap junction alpha-1 protein

1

1

Small-scale

0.479

High

1067727

EP300
Histone acetyltransferase p300

1

1

High-throughput

0.479

High

1292809

SKAP1
Src kinase-associated phosphoprotein 1

1

1

High-throughput

0.479

High

1412819

PCGF1
Polycomb group RING finger protein 1

1

1

High-throughput

0.479

High

1418397

PCGF6
Polycomb group RING finger protein 6

1

1

High-throughput

0.479

High

1437275

MTMR4
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR4

1

1

High-throughput

0.479

High

1437282

ARI1
E3 ubiquitin-protein ligase ARIH1

1

1

High-throughput

0.479

High

157866

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.458

High

294343

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.458

High

365470

PGK1
Phosphoglycerate kinase 1

1

0

Small-scale

0.458

High

551267

PCNA
Proliferating cell nuclear antigen

1

0

Small-scale

0.458

High

582964

EZRI
Ezrin

1

0

High-throughput

0.458

High

589723

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

683519

IKBA
NF-kappa-B inhibitor alpha

1

0

High-throughput

0.458

High

696543

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

971102

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

1033784

PO5F1
POU domain, class 5, transcription factor 1

1

0

High-throughput

0.458

High

1114336

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1138647

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

1161062

FSCN1
Fascin

1

0

High-throughput

0.458

High

1161404

HIF1A
Hypoxia-inducible factor 1-alpha

1

0

High-throughput

0.458

High

1229687

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

1255590

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1306921

DCP2
m7GpppN-mRNA hydrolase

1

0

High-throughput

0.458

High

1368130

HDAC2
Histone deacetylase 2

1

0

High-throughput

0.458

High

1397440

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.458

High

1431316

ATG5
Autophagy protein 5

1

0

High-throughput

0.458

High

1433925

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

1435303

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1437214

NANOG
Homeobox protein NANOG

1

0

High-throughput

0.458

High

1437276

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

1437277

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1437281

CIA2B
Cytosolic iron-sulfur assembly component 2B

1

0

High-throughput

0.458

High

58937

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

0

High-throughput

0.426

High

667460

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

Small-scale

0.426

High

1437271

LN28A
Protein lin-28 homolog A

1

0

High-throughput

0.426

High

1162740

QPCT
Glutaminyl-peptide cyclotransferase

3

0

High-throughput

0.347

High

1220492

F219B
Protein FAM219B

3

0

High-throughput

0.347

High

1437284

KPTN
KICSTOR complex protein kaptin

3

0

High-throughput

0.347

High

190489

COPT1
High affinity copper uptake protein 1

1

0

High-throughput

0.279

Low

1393542

MR1L1
MORF4 family-associated protein 1-like 1

1

0

High-throughput

0.279

Low

412631

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

769211

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

1383681

VP33A
Vacuolar protein sorting-associated protein 33A

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025