Protein: C2D1A
Coiled-coil and C2 domain-containing protein 1A (Akt kinase-interacting protein 1) (Five prime repressor element under dual repression-binding protein 1) (FRE under dual repression-binding protein 1) (Freud-1) (Putative NF-kappa-B-activating protein 023N)

Gene: C2D1A, CC2D1A
Organism: Homo sapiens
Interactions: 141
UniProt ID: Q6P1N0

Gene Ontology (top 5):
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001650 - fibrillar center
GO:0002087 - regulation of respiratory gaseous exchange by nervous system process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1241120

CHM4B
Charged multivesicular body protein 4b

4

5

High-throughput

0.894

High

252685

TSN3
Tetraspanin-3

3

2

High-throughput

0.667

High

384686

CRYAB
Alpha-crystallin B chain

3

5

High-throughput

0.667

High

845050

EAA3
Excitatory amino acid transporter 3

3

1

High-throughput

0.662

High

1241106

CHM4C
Charged multivesicular body protein 4c

1

5

High-throughput

0.656

High

1241114

CHM4A
Charged multivesicular body protein 4a

1

5

High-throughput

0.656

High

189640

STX7
Syntaxin-7

1

5

High-throughput

0.618

High

401003

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

3

High-throughput

0.618

High

1087152

STX4
Syntaxin-4

1

5

High-throughput

0.618

High

1041125

CAV1
Caveolin-1

2

4

High-throughput

0.611

High

1241108

MRAP2
Melanocortin-2 receptor accessory protein 2

2

0

High-throughput

0.602

High

1107835

SQSTM
Sequestosome-1

2

5

High-throughput

0.584

High

1123677

DCTN1
Dynactin subunit 1

2

6

High-throughput

0.584

High

1143365

PCM1
Pericentriolar material 1 protein

2

1

High-throughput

0.584

High

1241089

Z3H7A
Zinc finger CCCH domain-containing protein 7A

2

2

High-throughput

0.584

High

1241091

NIN
Ninein

2

16

High-throughput

0.584

High

1241134

NINL
Ninein-like protein

2

17

High-throughput

0.584

High

190396

COPT1
High affinity copper uptake protein 1

1

1

High-throughput

0.536

High

384450

CRYAA
Alpha-crystallin A chain

1

5

High-throughput

0.536

High

391297

FRIL
Ferritin light chain

1

1

High-throughput

0.536

High

928195

HAP1
Huntingtin-associated protein 1

1

4

High-throughput

0.536

High

930942

HSP72
Heat shock-related 70 kDa protein 2

1

3

High-throughput

0.536

High

1115736

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

11

High-throughput

0.536

High

1241094

RN149
E3 ubiquitin-protein ligase RNF149

1

4

High-throughput

0.536

High

1241103

H2B1H
Histone H2B type 1-H

1

20

High-throughput

0.515

High

536259

PPAL
Lysosomal acid phosphatase

1

0

High-throughput

0.513

High

1144032

TEBP
Prostaglandin E synthase 3

1

0

High-throughput

0.513

High

1158380

CDC37
Hsp90 co-chaperone Cdc37

1

0

High-throughput

0.486

High

1060882

LRP1
Prolow-density lipoprotein receptor-related protein 1

1

1

Small-scale

0.481

High

126658

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.479

High

172954

XPO1
Exportin-1

1

3

High-throughput

0.479

High

213468

CTIF
CBP80/20-dependent translation initiation factor

1

2

High-throughput

0.479

High

245332

CE104
Centrosomal protein of 104 kDa

1

1

High-throughput

0.479

High

290044

OFD1
Centriole and centriolar satellite protein OFD1

1

1

High-throughput

0.479

High

324157

CE152
Centrosomal protein of 152 kDa

1

4

High-throughput

0.479

High

345954

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

4

High-throughput

0.479

High

468502

HS90B
Heat shock protein HSP 90-beta

1

10

High-throughput

0.479

High

474755

VIME
Vimentin

1

8

High-throughput

0.479

High

483124

CLCA
Clathrin light chain A

1

3

High-throughput

0.479

High

483352

CLCB
Clathrin light chain B

1

3

High-throughput

0.479

High

541551

FGFR1
Fibroblast growth factor receptor 1

1

10

High-throughput

0.479

High

552614

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

2

High-throughput

0.479

High

556159

CADH1
Cadherin-1

1

5

High-throughput

0.479

High

560426

IFM1
Interferon-induced transmembrane protein 1

1

1

High-throughput

0.479

High

565940

EF2
Elongation factor 2

1

4

High-throughput

0.479

High

588943

RFA2
Replication protein A 32 kDa subunit

1

4

High-throughput

0.479

High

601336

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.479

High

604039

CXA1
Gap junction alpha-1 protein

1

1

High-throughput

0.479

High

605720

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

2

High-throughput

0.479

High

630846

RAB4A
Ras-related protein Rab-4A

1

5

High-throughput

0.479

High

631294

RAB5A
Ras-related protein Rab-5A

1

3

High-throughput

0.479

High

642934

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

3

High-throughput

0.479

High

648557

FGFR4
Fibroblast growth factor receptor 4

1

12

High-throughput

0.479

High

695730

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.479

High

830930

CCNF
Cyclin-F

1

2

High-throughput

0.479

High

862225

YAP1
Transcriptional coactivator YAP1

1

12

High-throughput

0.479

High

901882

RAB9A
Ras-related protein Rab-9A

1

7

High-throughput

0.479

High

952899

ACTB
Actin, cytoplasmic 1

1

5

High-throughput

0.479

High

953511

RAC3
Ras-related C3 botulinum toxin substrate 3

1

18

High-throughput

0.479

High

976345

RB11A
Ras-related protein Rab-11A

1

2

High-throughput

0.479

High

978091

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.479

High

988453

RAC1
Ras-related C3 botulinum toxin substrate 1

1

19

High-throughput

0.479

High

1026428

HSF1
Heat shock factor protein 1

1

3

High-throughput

0.479

High

1031420

IFM3
Interferon-induced transmembrane protein 3

1

1

High-throughput

0.479

High

1049430

1433F
14-3-3 protein eta

1

18

High-throughput

0.479

High

1113414

CUL3
Cullin-3

1

7

High-throughput

0.479

High

1129821

EPN4
Clathrin interactor 1

1

4

High-throughput

0.479

High

1138318

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

4

High-throughput

0.479

High

1141178

BRD3
Bromodomain-containing protein 3

1

14

High-throughput

0.479

High

1150392

NCOA2
Nuclear receptor coactivator 2

1

14

Small-scale

0.479

High

1159698

OCLN
Occludin

1

3

High-throughput

0.479

High

1165453

CPEB4
Cytoplasmic polyadenylation element-binding protein 4

1

8

High-throughput

0.479

High

1210877

CE170
Centrosomal protein of 170 kDa

1

14

High-throughput

0.479

High

1215458

CE162
Centrosomal protein of 162 kDa

1

13

High-throughput

0.479

High

1226135

CP135
Centrosomal protein of 135 kDa

1

8

High-throughput

0.479

High

1226884

A16L1
Autophagy-related protein 16-1

1

7

High-throughput

0.479

High

1233283

LTOR1
Ragulator complex protein LAMTOR1

1

1

High-throughput

0.479

High

1241079

LMTK1
Serine/threonine-protein kinase LMTK1

1

20

High-throughput

0.479

High

1241080

SYNE3
Nesprin-3

1

9

High-throughput

0.479

High

1241081

MEX3B
RNA-binding protein MEX3B

1

2

High-throughput

0.479

High

1241083

CE128
Centrosomal protein of 128 kDa

1

14

High-throughput

0.479

High

1241084

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

4

High-throughput

0.479

High

1241085

ZFY16
Zinc finger FYVE domain-containing protein 16

1

7

Small-scale

0.479

High

1241086

CNTRL
Centriolin

1

9

High-throughput

0.479

High

1241087

NAA40
N-alpha-acetyltransferase 40

1

2

High-throughput

0.479

High

1241088

HOOK3
Protein Hook homolog 3

1

11

High-throughput

0.479

High

1241093

F184A
Protein FAM184A

1

10

High-throughput

0.479

High

1241097

BICD2
Protein bicaudal D homolog 2

1

10

High-throughput

0.479

High

1241099

FBF1
Fas-binding factor 1

1

14

High-throughput

0.479

High

1241100

PARD3
Partitioning defective 3 homolog

1

9

High-throughput

0.479

High

1241101

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1241102

CSN5
COP9 signalosome complex subunit 5

1

2

High-throughput

0.479

High

1241105

ENTR1
Endosome-associated-trafficking regulator 1

1

1

High-throughput

0.479

High

1241107

BICD1
Protein bicaudal D homolog 1

1

9

High-throughput

0.479

High

1241109

DNJC1
DnaJ homolog subfamily C member 1

1

5

High-throughput

0.479

High

1241111

CEP89
Centrosomal protein of 89 kDa

1

13

High-throughput

0.479

High

1241112

NECD
Necdin

1

2

High-throughput

0.479

High

1241115

ACE2
Angiotensin-converting enzyme 2

1

2

High-throughput

0.479

High

1241116

CPEB1
Cytoplasmic polyadenylation element-binding protein 1

1

7

High-throughput

0.479

High

1241121

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.479

High

1241122

TRI36
E3 ubiquitin-protein ligase TRIM36

1

15

High-throughput

0.479

High

1241124

ARL8B
ADP-ribosylation factor-like protein 8B

1

2

High-throughput

0.479

High

1241128

MTMR4
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR4

1

4

High-throughput

0.479

High

1241129

ANFY1
Rabankyrin-5

1

6

High-throughput

0.479

High

1241130

ZO2
Tight junction protein 2

1

6

High-throughput

0.479

High

1241131

UBQL2
Ubiquilin-2

1

3

High-throughput

0.479

High

1241132

XPO7
Exportin-7

1

3

High-throughput

0.479

High

1241133

HOOK1
Protein Hook homolog 1

1

5

High-throughput

0.479

High

1241135

KLH20
Kelch-like protein 20

1

0

Small-scale

0.460

High

278874

PEX14
Peroxisomal membrane protein PEX14

1

0

High-throughput

0.458

High

341967

CEP43
Centrosomal protein 43

1

0

High-throughput

0.458

High

837671

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

0

High-throughput

0.458

High

894828

EMD
Emerin

1

0

High-throughput

0.458

High

1149306

STIL
SCL-interrupting locus protein

1

0

High-throughput

0.458

High

1241090

SPICE
Spindle and centriole-associated protein 1

1

0

High-throughput

0.458

High

1241110

CEP19
Centrosomal protein of 19 kDa

1

0

High-throughput

0.458

High

1241118

CEP44
Centrosomal protein of 44 kDa

1

0

High-throughput

0.458

High

1241123

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

0

Small-scale

0.458

High

1241126

MKS1
Tectonic-like complex member MKS1

1

0

High-throughput

0.458

High

58842

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

4

High-throughput

0.445

High

388419

B3AT
Band 3 anion transport protein

1

1

High-throughput

0.445

High

430042

JUN
Transcription factor Jun

1

17

High-throughput

0.445

High

934750

TERA
Transitional endoplasmic reticulum ATPase

1

1

High-throughput

0.445

High

943522

G6PT2
Glucose-6-phosphate exchanger SLC37A1

1

4

High-throughput

0.445

High

1199522

KLH22
Kelch-like protein 22

1

1

High-throughput

0.445

High

1216989

MEX3C
RNA-binding E3 ubiquitin-protein ligase MEX3C

1

3

Small-scale

0.445

High

1241098

G6PT3
Glucose-6-phosphate exchanger SLC37A2

1

4

High-throughput

0.445

High

1241113

PACN1
Protein kinase C and casein kinase substrate in neurons protein 1

1

6

High-throughput

0.445

High

768448

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

1241082

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.437

High

1241092

ARL10
ADP-ribosylation factor-like protein 10

1

3

High-throughput

0.437

High

1241117

UNK
RING finger protein unkempt homolog

1

4

High-throughput

0.437

High

1241125

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

1

High-throughput

0.437

High

231800

MFS11
UNC93-like protein MFSD11

1

0

High-throughput

0.426

High

1241096

MFSD8
Major facilitator superfamily domain-containing protein 8

1

0

High-throughput

0.426

High

1241127

SL2A8
Solute carrier family 2, facilitated glucose transporter member 8

1

0

High-throughput

0.426

High

886960

CEBPA
CCAAT/enhancer-binding protein alpha

1

12

High-throughput

0.408

High

1241095

SPX3
Sugar phosphate exchanger 3

1

4

High-throughput

0.407

High

1241104

LDAF1
Lipid droplet assembly factor 1

1

0

High-throughput

0.279

Low

139900

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

0

High-throughput

0.249

Low

1241119

MFSD1
Lysosomal dipeptide transporter MFSD1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025