Protein: TRAIP
E3 ubiquitin-protein ligase TRAIP (EC 2.3.2.27) (RING finger protein 206) (TRAF-interacting protein)

Gene: TRAIP
Organism: Homo sapiens
Interactions: 79
UniProt ID: Q9BWF2

Gene Ontology (top 5):
GO:0004842 - ubiquitin-protein transferase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0006915 - apoptotic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1416096

TRAIP
E3 ubiquitin-protein ligase TRAIP

5

18

Small-scale

0.928

High

957658

UBE2K
Ubiquitin-conjugating enzyme E2 K

2

9

High-throughput

0.783

High

971022

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

13

High-throughput

0.698

High

1005055

RNF4
E3 ubiquitin-protein ligase RNF4

1

5

High-throughput

0.698

High

1416098

UBE2Z
Ubiquitin-conjugating enzyme E2 Z

1

10

High-throughput

0.698

High

1090895

TRAF2
TNF receptor-associated factor 2

4

20

Small-scale

0.688

High

906767

UB2D1
Ubiquitin-conjugating enzyme E2 D1

1

7

Small-scale

0.647

High

957183

UB2D3
Ubiquitin-conjugating enzyme E2 D3

1

7

Small-scale

0.647

High

982302

UB2D2
Ubiquitin-conjugating enzyme E2 D2

1

7

Small-scale

0.647

High

1150075

MARE2
Microtubule-associated protein RP/EB family member 2

4

4

High-throughput

0.637

High

551235

PCNA
Proliferating cell nuclear antigen

2

0

Small-scale

0.628

High

1218752

UBE2U
Ubiquitin-conjugating enzyme E2 U

1

7

High-throughput

0.625

High

1093944

TRAF1
TNF receptor-associated factor 1

2

13

Small-scale

0.606

High

1416106

MARE3
Microtubule-associated protein RP/EB family member 3

2

4

High-throughput

0.606

High

1401494

UIMC1
BRCA1-A complex subunit RAP80

2

0

Small-scale

0.598

High

1094972

TRAF3
TNF receptor-associated factor 3

2

20

Small-scale

0.584

High

1416103

TBK1
Serine/threonine-protein kinase TBK1

2

19

Small-scale

0.584

High

180380

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

2

0

High-throughput

0.580

High

186168

LX15B
Polyunsaturated fatty acid lipoxygenase ALOX15B

2

0

High-throughput

0.580

High

1397103

CEP19
Centrosomal protein of 19 kDa

2

0

High-throughput

0.580

High

1412185

LXN
Latexin

2

1

High-throughput

0.553

High

849240

KSYK
Tyrosine-protein kinase SYK

1

20

Small-scale

0.552

High

1416107

POLH
DNA polymerase eta

1

3

Small-scale

0.552

High

783401

TRI23
E3 ubiquitin-protein ligase TRIM23

1

5

High-throughput

0.541

High

1357739

TRI41
E3 ubiquitin-protein ligase TRIM41

1

9

High-throughput

0.541

High

1407453

TS101
Tumor susceptibility gene 101 protein

1

1

High-throughput

0.541

High

1416109

RN114
E3 ubiquitin-protein ligase RNF114

1

8

High-throughput

0.541

High

648222

NDKB
Nucleoside diphosphate kinase B

1

3

High-throughput

0.536

High

75528

B3KSH4
Huntingtin interacting protein 2, isoform CRA_a

1

9

High-throughput

0.528

High

1093306

FLII
Protein flightless-1 homolog

1

8

Small-scale

0.527

High

1416100

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

4

Small-scale

0.527

High

322561

RNF37
RING finger protein 37

1

0

High-throughput

0.518

High

1394925

VPS50
Syndetin

1

0

High-throughput

0.513

High

423066

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.501

High

288500

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

1

18

High-throughput

0.481

High

1416099

MAGF1
Melanoma-associated antigen F1

1

10

Small-scale

0.481

High

1416101

POLK
DNA polymerase kappa

1

3

Small-scale

0.481

High

136724

TRAF5
TNF receptor-associated factor 5

1

20

Small-scale

0.479

High

214019

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

2

Small-scale

0.479

High

272748

BRE1B
E3 ubiquitin-protein ligase BRE1B

1

18

Small-scale

0.479

High

414543

P53
Cellular tumor antigen p53

1

5

Small-scale

0.479

High

440707

FYN
Tyrosine-protein kinase Fyn

1

19

High-throughput

0.479

High

487714

PARP1
Poly [ADP-ribose] polymerase 1

1

4

Small-scale

0.479

High

594091

NCK1
SH2/SH3 adapter protein NCK1

1

20

High-throughput

0.479

High

620561

NUCL
Nucleolin

1

1

Small-scale

0.479

High

669993

MCM3
DNA replication licensing factor MCM3

1

18

Small-scale

0.479

High

705921

TNR8
Tumor necrosis factor receptor superfamily member 8

1

7

Small-scale

0.479

High

755781

MCM4
DNA replication licensing factor MCM4

1

17

Small-scale

0.479

High

756041

MCM5
DNA replication licensing factor MCM5

1

17

Small-scale

0.479

High

756331

MCM7
DNA replication licensing factor MCM7

1

17

Small-scale

0.479

High

769775

RFC4
Replication factor C subunit 4

1

4

Small-scale

0.479

High

769901

RFC2
Replication factor C subunit 2

1

4

Small-scale

0.479

High

770048

RFC1
Replication factor C subunit 1

1

4

Small-scale

0.479

High

829141

RFC5
Replication factor C subunit 5

1

4

Small-scale

0.479

High

829264

RFC3
Replication factor C subunit 3

1

4

Small-scale

0.479

High

888303

MCM2
DNA replication licensing factor MCM2

1

18

Small-scale

0.479

High

987914

GRB2
Growth factor receptor-bound protein 2

1

20

High-throughput

0.479

High

1060483

DPOE1
DNA polymerase epsilon catalytic subunit A

1

1

Small-scale

0.479

High

1128273

MCM6
DNA replication licensing factor MCM6

1

18

Small-scale

0.479

High

1141902

EEA1
Early endosome antigen 1

1

20

High-throughput

0.479

High

1217910

BRE1A
E3 ubiquitin-protein ligase BRE1A

1

16

Small-scale

0.479

High

1226514

DCA15
DDB1- and CUL4-associated factor 15

1

2

High-throughput

0.479

High

1369758

RAD50
DNA repair protein RAD50

1

20

Small-scale

0.479

High

1371653

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

14

Small-scale

0.479

High

1407847

ANM1
Protein arginine N-methyltransferase 1

1

3

Small-scale

0.479

High

1413460

MCMBP
Mini-chromosome maintenance complex-binding protein

1

1

Small-scale

0.479

High

1416097

FACD2
Fanconi anemia group D2 protein

1

10

Small-scale

0.479

High

1416102

ZN212
Zinc finger protein 212

1

11

Small-scale

0.479

High

1416105

HECD1
E3 ubiquitin-protein ligase HECTD1

1

6

High-throughput

0.479

High

1416108

TRAF6
TNF receptor-associated factor 6

1

20

Small-scale

0.479

High

238603

RAD21
Double-strand-break repair protein rad21 homolog

1

0

High-throughput

0.458

High

542192

TOP1
DNA topoisomerase 1

1

0

Small-scale

0.458

High

814568

FEN1
Flap endonuclease 1

1

0

Small-scale

0.458

High

1157903

DDB1
DNA damage-binding protein 1

1

0

Small-scale

0.458

High

630350

TNR1B
Tumor necrosis factor receptor superfamily member 1B

1

7

Small-scale

0.437

High

1360740

JPH3
Junctophilin-3

1

0

High-throughput

0.268

Low

619102

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

0

High-throughput

0.249

Low

1416104

VANG2
Vang-like protein 2

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025