Protein: CTBL1
Beta-catenin-like protein 1 (Nuclear-associated protein) (NAP) (Testis development protein NYD-SP19)

Gene: CTBL1, CTNNBL1
Organism: Homo sapiens
Interactions: 139
UniProt ID: Q8WYA6

Gene Ontology (top 5):
GO:0000398 - mRNA splicing, via spliceosome
GO:0000974 - Prp19 complex
GO:0002250 - adaptive immune response
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1361536

CWC15
Spliceosome-associated protein CWC15 homolog

6

2

Small-scale

0.746

High

1361545

PRP19
Pre-mRNA-processing factor 19

5

1

Small-scale

0.718

High

1361510

CTBL1
Beta-catenin-like protein 1

1

1

Small-scale

0.710

High

1361519

CDC5L
Cell division cycle 5-like protein

6

0

Small-scale

0.704

High

478709

HXB5
Homeobox protein Hox-B5

3

1

High-throughput

0.667

High

416030

CP1A1
Cytochrome P450 1A1

3

0

High-throughput

0.638

High

1361525

THAP2
THAP domain-containing protein 2

3

0

High-throughput

0.638

High

1199120

ZN394
Zinc finger protein 394

2

1

High-throughput

0.628

High

1361515

CDA7L
Cell division cycle-associated 7-like protein

2

0

High-throughput

0.618

High

298040

SPF27
Pre-mRNA-splicing factor SPF27

3

0

Small-scale

0.616

High

1361523

AICDA
Single-stranded DNA cytosine deaminase

3

0

Small-scale

0.613

High

222512

PLRG1
Pleiotropic regulator 1

2

1

Small-scale

0.611

High

911324

IMA5
Importin subunit alpha-5

2

1

Small-scale

0.611

High

387860

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

2

0

High-throughput

0.602

High

1358165

SNR27
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein

2

0

High-throughput

0.602

High

1361517

UBP47
Ubiquitin carboxyl-terminal hydrolase 47

2

0

High-throughput

0.602

High

1361521

DUS23
Dual specificity protein phosphatase 23

2

0

High-throughput

0.602

High

1361530

ZN331
Zinc finger protein 331

2

0

High-throughput

0.602

High

343783

LDOC1
Protein LDOC1

2

0

High-throughput

0.601

High

982755

RS24
Small ribosomal subunit protein eS24

2

0

High-throughput

0.585

High

1127041

RBM39
RNA-binding protein 39

2

0

Small-scale

0.585

High

894060

MEOX2
Homeobox protein MOX-2

1

1

High-throughput

0.573

High

1359862

PRP31
U4/U6 small nuclear ribonucleoprotein Prp31

2

0

Small-scale

0.569

High

242436

PRKN
E3 ubiquitin-protein ligase parkin

2

0

High-throughput

0.559

High

372702

MYC
Myc proto-oncogene protein

2

0

High-throughput

0.559

High

1111145

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.549

High

1028488

BEX3
Protein BEX3

1

0

High-throughput

0.549

High

1281244

CATIP
Ciliogenesis-associated TTC17-interacting protein

1

0

High-throughput

0.549

High

1361528

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.549

High

1361533

ZHANG
CREB/ATF bZIP transcription factor

1

0

High-throughput

0.549

High

1361541

PRDM4
PR domain zinc finger protein 4

1

0

High-throughput

0.549

High

396609

ESR1
Estrogen receptor

2

0

High-throughput

0.547

High

272719

BRE1B
E3 ubiquitin-protein ligase BRE1B

1

1

High-throughput

0.536

High

973997

RUXF
Small nuclear ribonucleoprotein F

1

1

High-throughput

0.536

High

1005485

RBM6
RNA-binding protein 6

1

1

High-throughput

0.536

High

1361522

CRNL1
Crooked neck-like protein 1

1

1

High-throughput

0.536

High

1361527

SYF1
Pre-mRNA-splicing factor SYF1

1

1

High-throughput

0.536

High

1122941

WRN
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN

1

2

High-throughput

0.515

High

290656

SURF6
Surfeit locus protein 6

1

0

High-throughput

0.513

High

345206

ZMYM6
Zinc finger MYM-type protein 6

1

0

High-throughput

0.513

High

478136

SNRPA
U1 small nuclear ribonucleoprotein A

1

0

High-throughput

0.513

High

480245

RU1C
U1 small nuclear ribonucleoprotein C

1

0

High-throughput

0.513

High

542135

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.513

High

574395

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

0

High-throughput

0.513

High

611929

RL35A
Large ribosomal subunit protein eL33

1

0

High-throughput

0.513

High

854194

KI67
Proliferation marker protein Ki-67

1

0

High-throughput

0.513

High

860293

RS9
Small ribosomal subunit protein uS4

1

0

High-throughput

0.513

High

1100927

G3BP1
Ras GTPase-activating protein-binding protein 1

1

0

High-throughput

0.513

High

1109184

PRP4K
Serine/threonine-protein kinase PRP4 homolog

1

0

High-throughput

0.513

High

1149146

SF3A1
Splicing factor 3A subunit 1

1

0

High-throughput

0.513

High

1307499

RBM45
RNA-binding protein 45

1

0

High-throughput

0.513

High

1334701

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.513

High

1361511

GGH
Gamma-glutamyl hydrolase

1

0

High-throughput

0.513

High

1361512

ZN689
Zinc finger protein 689

1

0

High-throughput

0.513

High

1361514

NEIL1
Endonuclease 8-like 1

1

0

High-throughput

0.513

High

1361518

ZN830
Zinc finger protein 830

1

0

High-throughput

0.513

High

1361535

CENPM
Centromere protein M

1

0

High-throughput

0.513

High

1361542

ISY1
Pre-mRNA-splicing factor ISY1 homolog

1

0

High-throughput

0.513

High

1361546

PPIE
Peptidyl-prolyl cis-trans isomerase E

1

0

High-throughput

0.513

High

1361549

KIF3A
Kinesin-like protein KIF3A

1

0

High-throughput

0.513

High

1361516

VPS50
Syndetin

1

0

High-throughput

0.493

High

175739

SR140
U2 snRNP-associated SURP motif-containing protein

1

0

High-throughput

0.486

High

215157

PRPF3
U4/U6 small nuclear ribonucleoprotein Prp3

1

0

High-throughput

0.486

High

340657

STABP
STAM-binding protein

1

0

High-throughput

0.486

High

481342

HMGB1
High mobility group protein B1

1

0

High-throughput

0.486

High

833549

BUD31
Protein BUD31 homolog

1

0

High-throughput

0.486

High

965799

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

0

High-throughput

0.486

High

1006596

SRPK2
SRSF protein kinase 2

1

0

High-throughput

0.486

High

1091783

PP1R8
Nuclear inhibitor of protein phosphatase 1

1

0

High-throughput

0.486

High

1095151

RED
Protein Red

1

0

High-throughput

0.486

High

1361524

NSRP1
Nuclear speckle splicing regulatory protein 1

1

0

High-throughput

0.486

High

1361547

WBP11
WW domain-binding protein 11

1

0

High-throughput

0.486

High

964389

SUMO2
Small ubiquitin-related modifier 2

1

0

High-throughput

0.480

High

315821

RECQ4
ATP-dependent DNA helicase Q4

1

2

High-throughput

0.479

High

854896

RECQ1
ATP-dependent DNA helicase Q1

1

2

High-throughput

0.479

High

911024

IMA1
Importin subunit alpha-1

1

1

Small-scale

0.479

High

1227164

A16L1
Autophagy-related protein 16-1

1

2

High-throughput

0.479

High

1361513

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

2

High-throughput

0.479

High

1361520

MEP50
Methylosome protein WDR77

1

1

Small-scale

0.479

High

1361544

FZR1
Fizzy-related protein homolog

1

1

High-throughput

0.479

High

1361548

LSM2
U6 snRNA-associated Sm-like protein LSm2

1

1

High-throughput

0.479

High

716207

ERP29
Endoplasmic reticulum resident protein 29

1

0

High-throughput

0.460

High

157680

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.458

High

162646

ANM5
Protein arginine N-methyltransferase 5

1

0

Small-scale

0.458

High

227627

SPOP
Speckle-type POZ protein

1

0

High-throughput

0.458

High

248016

NUPR1
Nuclear protein 1

1

0

High-throughput

0.458

High

260225

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

346122

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

401217

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

447262

NPM
Nucleophosmin

1

0

Small-scale

0.458

High

589278

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

591754

H2AX
Histone H2AX

1

0

High-throughput

0.458

High

696065

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

761789

HSP74
Heat shock 70 kDa protein 4

1

0

Small-scale

0.458

High

768763

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

791585

SYUA
Alpha-synuclein

1

0

High-throughput

0.458

High

832758

BCL6
B-cell lymphoma 6 protein

1

0

High-throughput

0.458

High

838146

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

0

Small-scale

0.458

High

879309

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.458

High

904977

MECP2
Methyl-CpG-binding protein 2

1

0

High-throughput

0.458

High

934918

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

980057

H4
Histone H4

1

0

Small-scale

0.458

High

996507

ACTS
Actin, alpha skeletal muscle

1

0

Small-scale

0.458

High

998607

H31
Histone H3.1

1

0

High-throughput

0.458

High

1026481

HSF1
Heat shock factor protein 1

1

0

High-throughput

0.458

High

1033093

EWS
RNA-binding protein EWS

1

0

High-throughput

0.458

High

1100174

TIF1B
Transcription intermediary factor 1-beta

1

0

High-throughput

0.458

High

1107060

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

1113856

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1138444

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

1148629

SF3A2
Splicing factor 3A subunit 2

1

0

High-throughput

0.458

High

1155596

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.458

High

1220696

RN123
E3 ubiquitin-protein ligase RNF123

1

0

High-throughput

0.458

High

1311948

SKA3
Spindle and kinetochore-associated protein 3

1

0

Small-scale

0.458

High

1361526

BACD3
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3

1

0

Small-scale

0.458

High

1361531

DDX21
Nucleolar RNA helicase 2

1

0

Small-scale

0.458

High

1361532

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

0

Small-scale

0.458

High

1361534

RAD18
E3 ubiquitin-protein ligase RAD18

1

0

High-throughput

0.458

High

1361538

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1361539

TBK1
Serine/threonine-protein kinase TBK1

1

0

Small-scale

0.458

High

1361543

ZMYD8
MYND-type zinc finger-containing chromatin reader ZMYND8

1

0

High-throughput

0.458

High

348174

M4K4
Mitogen-activated protein kinase kinase kinase kinase 4

1

1

High-throughput

0.437

High

430176

JUN
Transcription factor Jun

1

0

High-throughput

0.426

High

1119224

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

0

High-throughput

0.426

High

1209452

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

1361540

DDX41
Probable ATP-dependent RNA helicase DDX41

1

0

High-throughput

0.426

High

288192

CLC3A
C-type lectin domain family 3 member A

2

0

High-throughput

0.328

High

1103718

JIP2
C-Jun-amino-terminal kinase-interacting protein 2

2

0

High-throughput

0.300

High

522282

OSTP
Osteopontin

1

0

High-throughput

0.282

High

343152

CXL14
C-X-C motif chemokine 14

1

0

High-throughput

0.279

Low

1348930

ZCH10
Zinc finger CCHC domain-containing protein 10

1

0

High-throughput

0.265

Low

1361529

LUC7L
Putative RNA-binding protein Luc7-like 1

1

0

High-throughput

0.265

Low

136948

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

0

High-throughput

0.249

Low

189747

STX7
Syntaxin-7

1

0

High-throughput

0.249

Low

1254845

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1290619

ZCH18
Zinc finger CCCH domain-containing protein 18

1

0

High-throughput

0.249

Low

1361537

HECW2
E3 ubiquitin-protein ligase HECW2

1

0

High-throughput

0.249

Low

255140

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025