Protein: SOSB1
SOSS complex subunit B1 (Nucleic acid-binding protein 2) (Oligonucleotide/oligosaccharide-binding fold-containing protein 2B) (Sensor of single-strand DNA complex subunit B1) (Sensor of ssDNA subunit B1) (SOSS-B1) (Single-stranded DNA-binding protein 1) (hSSB1)

Gene: SOSB1, NABP2
Organism: Homo sapiens
Interactions: 60
UniProt ID: Q9BQ15

Gene Ontology (top 5):
GO:0000724 - double-strand break repair via homologous recombination
GO:0000781 - chromosome, telomeric region
GO:0003677 - DNA binding
GO:0003697 - single-stranded DNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1229197

INT3
Integrator complex subunit 3

7

1

Small-scale

0.970

High

1409899

SOSSC
SOSS complex subunit C

3

1

Small-scale

0.667

High

1409904

INT6
Integrator complex subunit 6

3

2

Small-scale

0.656

High

1243327

INT5
Integrator complex subunit 5

2

1

High-throughput

0.611

High

262124

NBN
Nibrin

2

0

Small-scale

0.598

High

414506

P53
Cellular tumor antigen p53

1

1

Small-scale

0.561

High

1067651

EP300
Histone acetyltransferase p300

2

0

Small-scale

0.559

High

717962

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

1

High-throughput

0.554

High

808155

CDN1A
Cyclin-dependent kinase inhibitor 1

1

0

Small-scale

0.537

High

1369753

RAD50
DNA repair protein RAD50

1

0

Small-scale

0.537

High

1409903

FBXL5
F-box/LRR-repeat protein 5

1

0

Small-scale

0.537

High

128054

PSD11
26S proteasome non-ATPase regulatory subunit 11

1

1

High-throughput

0.536

High

1136580

PSMD6
26S proteasome non-ATPase regulatory subunit 6

1

1

High-throughput

0.536

High

1148874

PP1R7
Protein phosphatase 1 regulatory subunit 7

1

1

High-throughput

0.536

High

1215011

INT11
Integrator complex subunit 11

1

2

High-throughput

0.536

High

1409900

INT9
Integrator complex subunit 9

1

2

High-throughput

0.536

High

1102241

ATM
Serine-protein kinase ATM

1

0

Small-scale

0.530

High

130597

SPT5H
Transcription elongation factor SPT5

1

0

High-throughput

0.513

High

247159

TBCD4
TBC1 domain family member 4

1

0

High-throughput

0.513

High

330502

LC7L3
Luc7-like protein 3

1

0

High-throughput

0.513

High

723068

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

0

High-throughput

0.513

High

888811

VPS41
Vacuolar protein sorting-associated protein 41 homolog

1

0

High-throughput

0.513

High

906591

PSMD7
26S proteasome non-ATPase regulatory subunit 7

1

0

High-throughput

0.513

High

1065393

SSRP1
FACT complex subunit SSRP1

1

0

High-throughput

0.513

High

1163172

H2B2E
Histone H2B type 2-E

1

0

High-throughput

0.513

High

1185219

EDRF1
Erythroid differentiation-related factor 1

1

0

High-throughput

0.513

High

1260317

INT8
Integrator complex subunit 8

1

0

High-throughput

0.513

High

1273226

RIR2B
Ribonucleoside-diphosphate reductase subunit M2 B

1

0

High-throughput

0.513

High

1295295

P66A
Transcriptional repressor p66-alpha

1

0

High-throughput

0.513

High

1380477

YIPF5
Protein YIPF5

1

0

High-throughput

0.513

High

1381265

FBXW5
F-box/WD repeat-containing protein 5

1

0

High-throughput

0.513

High

1393574

INT4
Integrator complex subunit 4

1

0

High-throughput

0.513

High

1397871

KLH15
Kelch-like protein 15

1

0

High-throughput

0.513

High

1409895

BUD13
BUD13 homolog

1

0

High-throughput

0.513

High

1409897

CPAP
Centrosomal P4.1-associated protein

1

0

High-throughput

0.513

High

1409898

BIRC6
Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6

1

0

High-throughput

0.513

High

1409905

VPS4A
Vacuolar protein sorting-associated protein 4A

1

0

High-throughput

0.513

High

1409906

PSD13
26S proteasome non-ATPase regulatory subunit 13

1

0

High-throughput

0.513

High

1206361

INT6L
Integrator complex subunit 6-like

1

2

High-throughput

0.489

High

926402

BLM
RecQ-like DNA helicase BLM

1

0

Small-scale

0.479

High

799441

BRCA1
Breast cancer type 1 susceptibility protein

1

1

High-throughput

0.479

High

1112684

CUL1
Cullin-1

1

1

Small-scale

0.479

High

1114128

CUL3
Cullin-3

1

1

High-throughput

0.479

High

1367122

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

1409902

XPO7
Exportin-7

1

1

High-throughput

0.479

High

297860

PIAS2
E3 SUMO-protein ligase PIAS2

1

0

Small-scale

0.458

High

363783

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.458

High

372976

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

880370

RL34
Large ribosomal subunit protein eL34

1

0

High-throughput

0.458

High

892930

MRE11
Double-strand break repair protein MRE11

1

0

Small-scale

0.458

High

992316

SKP1
S-phase kinase-associated protein 1

1

0

Small-scale

0.458

High

1048660

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

Small-scale

0.458

High

1055961

RAD51
DNA repair protein RAD51 homolog 1

1

0

Small-scale

0.458

High

1323837

INT1
Integrator complex subunit 1

1

0

High-throughput

0.458

High

1409896

SENP2
Sentrin-specific protease 2

1

0

Small-scale

0.458

High

1357368

NAT14
Probable N-acetyltransferase 14

1

0

High-throughput

0.426

High

943449

PIGP
Phosphatidylinositol N-acetylglucosaminyltransferase subunit P

1

0

High-throughput

0.282

High

1291669

CMTD1
Catechol O-methyltransferase domain-containing protein 1

1

0

High-throughput

0.279

Low

1409901

MTCH1
Mitochondrial carrier homolog 1

1

0

High-throughput

0.279

Low

1330738

SIGL1
SIGLEC family-like protein 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025