Protein: MATK
Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (CSK homologous kinase) (CHK) (Hematopoietic consensus tyrosine-lacking kinase) (Protein kinase HYL) (Tyrosine-protein kinase CTK)

Gene: MATK
Organism: Homo sapiens
Interactions: 38
UniProt ID: P42679

Gene Ontology (top 5):
GO:0004713 - protein tyrosine kinase activity
GO:0004715 - non-membrane spanning protein tyrosine kinase activity
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0006468 - protein phosphorylation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

383670

ERBB2
Receptor tyrosine-protein kinase erbB-2

3

20

Small-scale

0.857

High

782750

CSK
Tyrosine-protein kinase CSK

2

19

High-throughput

0.811

High

788968

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

18

Small-scale

0.799

High

499241

KIT
Mast/stem cell growth factor receptor Kit

2

20

Small-scale

0.778

High

788967

LRRK1
Leucine-rich repeat serine/threonine-protein kinase 1

2

7

High-throughput

0.778

High

384433

NTRK1
High affinity nerve growth factor receptor

1

20

Small-scale

0.724

High

788961

SHPS1
Tyrosine-protein phosphatase non-receptor type substrate 1

3

5

Small-scale

0.693

High

441459

MET
Hepatocyte growth factor receptor

1

20

High-throughput

0.692

High

788973

BACE2
Beta-secretase 2

1

1

High-throughput

0.665

High

522839

SRC
Proto-oncogene tyrosine-protein kinase Src

1

20

Small-scale

0.647

High

601834

ERBB3
Receptor tyrosine-protein kinase erbB-3

1

20

High-throughput

0.647

High

681715

AKT1
RAC-alpha serine/threonine-protein kinase

1

20

Small-scale

0.647

High

788958

MATK
Megakaryocyte-associated tyrosine-protein kinase

1

19

Small-scale

0.647

High

788963

ILK
Integrin-linked protein kinase

1

17

Small-scale

0.647

High

788965

ERBB4
Receptor tyrosine-protein kinase erbB-4

1

20

High-throughput

0.647

High

788972

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

14

Small-scale

0.647

High

788964

FAK2
Protein-tyrosine kinase 2-beta

1

20

Small-scale

0.625

High

338080

EGFR
Epidermal growth factor receptor

1

20

Small-scale

0.618

High

435573

IGF1R
Insulin-like growth factor 1 receptor

1

20

Small-scale

0.618

High

683883

1433S
14-3-3 protein sigma

1

20

High-throughput

0.618

High

788960

1433E
14-3-3 protein epsilon

1

5

High-throughput

0.618

High

616952

PTPRD
Receptor-type tyrosine-protein phosphatase delta

1

20

Small-scale

0.579

High

788971

KLK6
Kallikrein-6

1

0

High-throughput

0.556

High

207299

FRS3
Fibroblast growth factor receptor substrate 3

2

20

High-throughput

0.542

High

487202

ANDR
Androgen receptor

1

20

High-throughput

0.536

High

437965

HS90B
Heat shock protein HSP 90-beta

1

20

High-throughput

0.515

High

132297

CAC1A
Voltage-dependent P/Q-type calcium channel subunit alpha-1A

1

4

High-throughput

0.508

High

501793

BIP
Endoplasmic reticulum chaperone BiP

1

20

Small-scale

0.501

High

751519

GRP75
Stress-70 protein, mitochondrial

1

20

Small-scale

0.501

High

788962

EWS
RNA-binding protein EWS

1

3

High-throughput

0.494

High

431625

HS90A
Heat shock protein HSP 90-alpha

1

20

High-throughput

0.479

High

562054

CD36
Platelet glycoprotein 4

1

6

Small-scale

0.479

High

788959

PAXI
Paxillin

1

20

Small-scale

0.479

High

788966

CDC37
Hsp90 co-chaperone Cdc37

1

15

High-throughput

0.479

High

788970

NUDC2
NudC domain-containing protein 2

1

3

High-throughput

0.479

High

749187

BRCA1
Breast cancer type 1 susceptibility protein

1

9

Small-scale

0.437

High

788969

NOC3L
Nucleolar complex protein 3 homolog

1

0

High-throughput

0.269

Low


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Last updated: 15 Jul 2024