Protein: APC16
Anaphase-promoting complex subunit 16 (APC16) (Cyclosome subunit 16)

Gene: APC16, ANAPC16
Organism: Homo sapiens
Interactions: 65
UniProt ID: Q96DE5

Gene Ontology (top 5):
GO:0000776 - kinetochore
GO:0005654 - nucleoplasm
GO:0005680 - anaphase-promoting complex
GO:0005829 - cytosol
GO:0007346 - regulation of mitotic cell cycle

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

718607

CDC27
Cell division cycle protein 27 homolog

9

4

Small-scale

0.968

High

1093028

CDC16
Cell division cycle protein 16 homolog

6

5

High-throughput

0.949

High

1387378

APC7
Anaphase-promoting complex subunit 7

6

5

Small-scale

0.938

High

1387377

CDC23
Cell division cycle protein 23 homolog

5

5

High-throughput

0.925

High

1086891

CDC20
Cell division cycle protein 20 homolog

7

1

Small-scale

0.745

High

1387380

APC4
Anaphase-promoting complex subunit 4

9

0

Small-scale

0.716

High

1387384

FZR1
Fizzy-related protein homolog

4

1

High-throughput

0.691

High

1387372

APC13
Anaphase-promoting complex subunit 13

4

0

High-throughput

0.667

High

292860

GRAP2
GRB2-related adapter protein 2

3

2

High-throughput

0.667

High

1387373

APC1
Anaphase-promoting complex subunit 1

4

0

High-throughput

0.661

High

1387379

APC5
Anaphase-promoting complex subunit 5

4

0

High-throughput

0.661

High

251795

BUB1B
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta

4

0

High-throughput

0.658

High

1340911

CDC26
Anaphase-promoting complex subunit CDC26

4

0

High-throughput

0.658

High

1387381

ANC2
Anaphase-promoting complex subunit 2

4

0

High-throughput

0.658

High

1387383

FBX5
F-box only protein 5

3

0

High-throughput

0.634

High

1387385

APC10
Anaphase-promoting complex subunit 10

3

0

High-throughput

0.634

High

948571

APC15
Anaphase-promoting complex subunit 15

2

0

High-throughput

0.602

High

1326636

KIF2B
Kinesin-like protein KIF2B

2

0

High-throughput

0.602

High

224340

BUB3
Mitotic checkpoint protein BUB3

2

0

High-throughput

0.585

High

908848

NEK2
Serine/threonine-protein kinase Nek2

2

0

High-throughput

0.585

High

269336

HSF2B
Heat shock factor 2-binding protein

2

0

High-throughput

0.580

High

1214498

Q5T8C6
Cell division cycle 16

1

5

High-throughput

0.575

High

1385486

P5CR2
Pyrroline-5-carboxylate reductase 2

1

1

High-throughput

0.536

High

1195416

Q4KMX6
Anaphase-promoting complex subunit 7

1

5

High-throughput

0.514

High

440670

FYN
Tyrosine-protein kinase Fyn

1

0

High-throughput

0.513

High

777312

AHR
Aryl hydrocarbon receptor

1

0

High-throughput

0.513

High

936207

MANF
Mesencephalic astrocyte-derived neurotrophic factor

1

0

High-throughput

0.513

High

1034116

PLCB3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3

1

0

High-throughput

0.513

High

1099752

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

0

High-throughput

0.513

High

1106290

ROCK1
Rho-associated protein kinase 1

1

0

High-throughput

0.513

High

1127750

HLTF
Helicase-like transcription factor

1

0

High-throughput

0.513

High

1324909

RHG18
Rho GTPase-activating protein 18

1

0

High-throughput

0.513

High

1328897

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

0

High-throughput

0.513

High

1339549

NEUA
N-acylneuraminate cytidylyltransferase

1

0

High-throughput

0.513

High

1353319

DOK4
Docking protein 4

1

0

High-throughput

0.513

High

1382361

SPSB4
SPRY domain-containing SOCS box protein 4

1

0

High-throughput

0.513

High

1387369

CCD43
Coiled-coil domain-containing protein 43

1

0

High-throughput

0.513

High

1387371

TCPH
T-complex protein 1 subunit eta

1

0

High-throughput

0.513

High

1387375

MED17
Mediator of RNA polymerase II transcription subunit 17

1

0

High-throughput

0.513

High

1387382

PO2F3
POU domain, class 2, transcription factor 3

1

0

High-throughput

0.513

High

1387386

SNX9
Sorting nexin-9

1

0

High-throughput

0.513

High

733976

P5CR1
Pyrroline-5-carboxylate reductase 1, mitochondrial

1

1

High-throughput

0.489

High

1279881

RBBP6
E3 ubiquitin-protein ligase RBBP6

1

1

Small-scale

0.481

High

1088957

TP53B
TP53-binding protein 1

1

1

High-throughput

0.479

High

1129692

MDC1
Mediator of DNA damage checkpoint protein 1

1

1

High-throughput

0.479

High

315866

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

799382

BRCA1
Breast cancer type 1 susceptibility protein

1

0

High-throughput

0.458

High

980116

H4
Histone H4

1

0

High-throughput

0.458

High

998661

H31
Histone H3.1

1

0

High-throughput

0.458

High

1115894

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

0

High-throughput

0.458

High

1287001

UBP37
Ubiquitin carboxyl-terminal hydrolase 37

1

0

Small-scale

0.458

High

1366988

ESR2
Estrogen receptor beta

1

0

High-throughput

0.458

High

1384238

SH3K1
SH3 domain-containing kinase-binding protein 1

1

1

High-throughput

0.445

High

1387374

MAGIX
PDZ domain-containing protein MAGIX

3

0

High-throughput

0.347

High

1244442

CP087
UPF0547 protein C16orf87

2

0

High-throughput

0.328

High

351286

TTLL1
Polyglutamylase complex subunit TTLL1

2

0

High-throughput

0.318

High

377084

PENK
Proenkephalin-A [Cleaved into: Synenkephalin; Met-enkephalin

2

0

High-throughput

0.318

High

66257

MET15
12S rRNA N(4)-cytidine methyltransferase METTL15

1

0

High-throughput

0.279

Low

138861

STK25
Serine/threonine-protein kinase 25

1

0

High-throughput

0.279

Low

1280209

MILR1
Allergin-1

1

0

High-throughput

0.279

Low

1387368

BT3L4
Transcription factor BTF3 homolog 4

1

0

High-throughput

0.279

Low

1387370

PUS7
Pseudouridylate synthase 7 homolog

1

0

High-throughput

0.279

Low

1387376

CFA97
Cilia- and flagella-associated protein 97

1

0

High-throughput

0.279

Low

1141255

BRD3
Bromodomain-containing protein 3

1

0

High-throughput

0.249

Low

248231

NDK8
Putative nucleoside diphosphate kinase

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025