Protein: MRP
MARCKS-related protein (MARCKS-like protein 1) (Macrophage myristoylated alanine-rich C kinase substrate) (Mac-MARCKS) (MacMARCKS)

Gene: MRP, MARCKSL1
Organism: Homo sapiens
Interactions: 112
UniProt ID: P49006

Gene Ontology (top 5):
GO:0005516 - calmodulin binding
GO:0005737 - cytoplasm
GO:0005856 - cytoskeleton
GO:0005886 - plasma membrane
GO:0007015 - actin filament organization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

375288

RASK
GTPase KRas

4

3

High-throughput

0.676

High

251438

NMT2
Glycylpeptide N-tetradecanoyltransferase 2

2

1

High-throughput

0.628

High

719600

NMT1
Glycylpeptide N-tetradecanoyltransferase 1

2

1

High-throughput

0.628

High

878357

VPP2
V-type proton ATPase 116 kDa subunit a 2

2

1

High-throughput

0.628

High

389597

RET4
Retinol-binding protein 4

2

0

High-throughput

0.602

High

878339

SCRN2
Secernin-2

2

0

High-throughput

0.602

High

878296

CDC42
Cell division control protein 42 homolog

2

6

High-throughput

0.595

High

373833

RASN
GTPase NRas

2

3

High-throughput

0.584

High

374463

RASH
GTPase HRas

2

2

High-throughput

0.584

High

540357

LAMP1
Lysosome-associated membrane glycoprotein 1

2

2

High-throughput

0.584

High

395681

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

878315

DCTN2
Dynactin subunit 2

1

0

Small-scale

0.568

High

358638

LDHA
L-lactate dehydrogenase A chain

2

0

High-throughput

0.559

High

878301

ARF6
ADP-ribosylation factor 6

2

0

High-throughput

0.559

High

878317

MK14
Mitogen-activated protein kinase 14

1

1

High-throughput

0.536

High

878337

VPP1
V-type proton ATPase 116 kDa subunit a 1

1

1

High-throughput

0.536

High

529329

TAU
Microtubule-associated protein tau

2

0

High-throughput

0.528

High

878328

SH2D3
SH2 domain-containing protein 3C

2

1

High-throughput

0.521

High

213859

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

0

High-throughput

0.513

High

361164

SODC
Superoxide dismutase [Cu-Zn]

1

0

High-throughput

0.513

High

685123

PAX6
Paired box protein Pax-6

1

0

High-throughput

0.513

High

878310

KPCZ
Protein kinase C zeta type

1

0

High-throughput

0.513

High

878312

EPS8
Epidermal growth factor receptor kinase substrate 8

1

0

High-throughput

0.513

High

878313

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

0

High-throughput

0.513

High

878319

TM63B
Mechanosensitive cation channel TMEM63B

1

0

High-throughput

0.513

High

878325

MYLK4
Myosin light chain kinase family member 4

1

0

High-throughput

0.513

High

878326

CCAR1
Cell division cycle and apoptosis regulator protein 1

1

0

High-throughput

0.513

High

878330

AT11C
Phospholipid-transporting ATPase IG

1

0

High-throughput

0.513

High

878333

HASP
Serine/threonine-protein kinase haspin

1

0

High-throughput

0.513

High

878334

KBTB7
Kelch repeat and BTB domain-containing protein 7

1

0

High-throughput

0.513

High

878346

PP4R2
Serine/threonine-protein phosphatase 4 regulatory subunit 2

1

0

High-throughput

0.513

High

878359

VATD
V-type proton ATPase subunit D

1

0

High-throughput

0.513

High

180747

TIF1A
Transcription intermediary factor 1-alpha

1

1

High-throughput

0.489

High

189453

STX7
Syntaxin-7

1

1

High-throughput

0.479

High

561945

LAMP2
Lysosome-associated membrane glycoprotein 2

1

2

High-throughput

0.479

High

580926

RAC2
Ras-related C3 botulinum toxin substrate 2

1

5

High-throughput

0.479

High

601211

RHOQ
Rho-related GTP-binding protein RhoQ

1

6

High-throughput

0.479

High

878293

ARL4C
ADP-ribosylation factor-like protein 4C

1

2

High-throughput

0.479

High

878298

RHOA
Transforming protein RhoA

1

5

High-throughput

0.479

High

878302

RHOB
Rho-related GTP-binding protein RhoB

1

6

High-throughput

0.479

High

878303

RAC1
Ras-related C3 botulinum toxin substrate 1

1

5

High-throughput

0.479

High

878305

RHOG
Rho-related GTP-binding protein RhoG

1

5

High-throughput

0.479

High

878311

STX4
Syntaxin-4

1

1

High-throughput

0.479

High

878316

KS6A2
Ribosomal protein S6 kinase alpha-2

1

1

High-throughput

0.479

High

878323

RHOU
Rho-related GTP-binding protein RhoU

1

6

High-throughput

0.479

High

878327

ARL14
ADP-ribosylation factor-like protein 14

1

1

High-throughput

0.479

High

878342

DNJC5
DnaJ homolog subfamily C member 5

1

1

High-throughput

0.479

High

878345

ARL15
ADP-ribosylation factor-like protein 15

1

2

High-throughput

0.479

High

878350

DNJ5B
DnaJ homolog subfamily C member 5B

1

1

High-throughput

0.479

High

878353

TBK1
Serine/threonine-protein kinase TBK1

1

1

High-throughput

0.479

High

878356

LAMP3
Lysosome-associated membrane glycoprotein 3

1

2

High-throughput

0.479

High

878360

ARL5A
ADP-ribosylation factor-like protein 5A

1

1

High-throughput

0.479

High

798835

BRCA1
Breast cancer type 1 susceptibility protein

1

0

High-throughput

0.460

High

164284

NRP1
Neuropilin-1

1

0

High-throughput

0.458

High

217956

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

241056

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

252334

TLR2
Toll-like receptor 2

1

0

Small-scale

0.458

High

293365

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.458

High

315270

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

371452

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

400471

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

411565

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.458

High

463402

LYN
Tyrosine-protein kinase Lyn

1

0

High-throughput

0.458

High

536734

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

563411

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.458

High

605598

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

0

High-throughput

0.458

High

606412

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.458

High

640122

EPHA1
Ephrin type-A receptor 1

1

0

High-throughput

0.458

High

667637

CDK2
Cyclin-dependent kinase 2

1

0

High-throughput

0.458

High

715479

MARCS
Myristoylated alanine-rich C-kinase substrate

1

0

High-throughput

0.458

High

764538

CTNB1
Catenin beta-1

1

0

High-throughput

0.458

High

774203

BASI
Basigin

1

0

High-throughput

0.458

High

845560

MUC18
Cell surface glycoprotein MUC18

1

0

High-throughput

0.458

High

878291

RAB5C
Ras-related protein Rab-5C

1

0

High-throughput

0.458

High

878292

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

878297

RAB2A
Ras-related protein Rab-2A

1

0

High-throughput

0.458

High

878304

ACTC
Actin, alpha cardiac muscle 1

1

0

High-throughput

0.458

High

878306

VIGLN
Vigilin

1

0

High-throughput

0.458

High

878307

EWS
RNA-binding protein EWS

1

0

High-throughput

0.458

High

878308

CAV1
Caveolin-1

1

0

High-throughput

0.458

High

878309

TF65
Transcription factor p65

1

0

High-throughput

0.458

High

878322

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

878335

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

878341

FMNL2
Formin-like protein 2

1

0

High-throughput

0.458

High

878348

TM216
Transmembrane protein 216

1

0

High-throughput

0.458

High

878351

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

878354

UBQL2
Ubiquilin-2

1

0

High-throughput

0.458

High

878295

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

1

High-throughput

0.445

High

878332

DJB14
DnaJ homolog subfamily B member 14

1

1

High-throughput

0.437

High

878336

ESR2
Estrogen receptor beta

1

1

High-throughput

0.437

High

878343

Q9H4D1
Receptor-interacting serine/threonine-protein kinase 4

1

1

High-throughput

0.437

High

878352

SEC63
Translocation protein SEC63 homolog

1

1

High-throughput

0.437

High

878294

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

0

High-throughput

0.426

High

878321

PKHA7
Pleckstrin homology domain-containing family A member 7

1

0

High-throughput

0.426

High

878340

OTUB1
Ubiquitin thioesterase OTUB1

1

0

High-throughput

0.426

High

878347

SPHK1
Sphingosine kinase 1

1

0

Small-scale

0.426

High

878355

S23A1
Solute carrier family 23 member 1

1

0

High-throughput

0.426

High

878314

TOP3A
DNA topoisomerase 3-alpha

2

0

High-throughput

0.328

High

878320

P4R3A
Serine/threonine-protein phosphatase 4 regulatory subunit 3A

2

0

High-throughput

0.328

High

878338

SNX21
Sorting nexin-21

2

0

High-throughput

0.328

High

878344

RMI1
RecQ-mediated genome instability protein 1

2

0

High-throughput

0.328

High

878349

BCCIP
BRCA2 and CDKN1A-interacting protein

2

0

High-throughput

0.328

High

385546

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.279

Low

773823

SOAT1
Sterol O-acyltransferase 1

1

0

High-throughput

0.279

Low

878358

LOXL2
Lysyl oxidase homolog 2

1

0

Small-scale

0.276

Low

481157

HMGB1
High mobility group protein B1

1

0

High-throughput

0.249

Low

878299

WDR5
WD repeat-containing protein 5

1

0

High-throughput

0.249

Low

878300

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.249

Low

878318

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

0

High-throughput

0.249

Low

878324

TMM17
Transmembrane protein 17

1

0

High-throughput

0.249

Low

878329

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

0

High-throughput

0.249

Low

878331

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025