Protein: PP4R2
Serine/threonine-protein phosphatase 4 regulatory subunit 2

Gene: PP4R2, PPP4R2
Organism: Homo sapiens
Interactions: 86
UniProt ID: Q9NY27

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005813 - centrosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

952027

PP4C
Serine/threonine-protein phosphatase 4 catalytic subunit

14

1

Small-scale

0.765

High

1234626

P4R3A
Serine/threonine-protein phosphatase 4 regulatory subunit 3A

7

2

Small-scale

0.753

High

1208200

P4R3B
Serine/threonine-protein phosphatase 4 regulatory subunit 3B

7

2

Small-scale

0.749

High

1452217

PPME1
Protein phosphatase methylesterase 1

5

0

High-throughput

0.688

High

1365856

PRP16
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16

4

0

High-throughput

0.670

High

1452215

SF3B6
Splicing factor 3B subunit 6

2

1

High-throughput

0.635

High

1144591

PTPA
Serine/threonine-protein phosphatase 2A activator

3

0

High-throughput

0.634

High

262574

MCE1
mRNA-capping enzyme

3

0

High-throughput

0.628

High

1452218

TSSC4
U5 small nuclear ribonucleoprotein TSSC4

3

0

High-throughput

0.622

High

286092

SF3B1
Splicing factor 3B subunit 1

2

0

High-throughput

0.608

High

471936

RU2B
U2 small nuclear ribonucleoprotein B''

2

0

High-throughput

0.608

High

1105425

SF3B2
Splicing factor 3B subunit 2

2

0

High-throughput

0.608

High

1148068

SF3B3
Splicing factor 3B subunit 3

2

0

High-throughput

0.608

High

1148570

SF3B4
Splicing factor 3B subunit 4

2

0

High-throughput

0.608

High

1416253

SF3B5
Splicing factor 3B subunit 5

2

0

High-throughput

0.608

High

1416391

NADAP
Kanadaptin

2

0

High-throughput

0.608

High

69834

ZN785
Zinc finger protein 785

2

0

High-throughput

0.602

High

1131139

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

2

0

High-throughput

0.602

High

1334419

UXS1
UDP-glucuronic acid decarboxylase 1

2

0

High-throughput

0.602

High

1402087

CRML
Protein cramped-like

2

0

High-throughput

0.602

High

485749

RU2A
U2 small nuclear ribonucleoprotein A'

2

0

High-throughput

0.585

High

130633

SPT5H
Transcription elongation factor SPT5

2

0

High-throughput

0.585

High

1452211

LCMT1
Leucine carboxyl methyltransferase 1

2

0

High-throughput

0.585

High

1452213

PRP19
Pre-mRNA-processing factor 19

2

0

High-throughput

0.585

High

589871

RFA2
Replication protein A 32 kDa subunit

2

0

Small-scale

0.559

High

1340600

CT453
Cancer/testis antigen family 45 member A3

2

3

High-throughput

0.552

High

1274055

PHF5A
PHD finger-like domain-containing protein 5A

1

0

High-throughput

0.530

High

63870

TPC13
Trafficking protein particle complex subunit 13

1

0

High-throughput

0.513

High

273371

NPHP4
Nephrocystin-4

1

0

High-throughput

0.513

High

298455

DNJC8
DnaJ homolog subfamily C member 8

1

0

High-throughput

0.513

High

849262

KSYK
Tyrosine-protein kinase SYK

1

0

High-throughput

0.513

High

878346

MRP
MARCKS-related protein

1

0

High-throughput

0.513

High

973611

RS11
Small ribosomal subunit protein uS17

1

0

High-throughput

0.513

High

974680

SMD2
Small nuclear ribonucleoprotein Sm D2

1

0

High-throughput

0.513

High

982137

RAP1A
Ras-related protein Rap-1A

1

0

High-throughput

0.513

High

1037675

RL18A
Large ribosomal subunit protein eL20

1

0

High-throughput

0.513

High

1119905

CKAP5
Cytoskeleton-associated protein 5

1

0

High-throughput

0.513

High

1149207

SF3A1
Splicing factor 3A subunit 1

1

0

High-throughput

0.513

High

1245183

MDEAS
Mitotic deacetylase-associated SANT domain protein

1

0

High-throughput

0.513

High

1400399

PUS7
Pseudouridylate synthase 7 homolog

1

0

High-throughput

0.513

High

1439287

E41L5
Band 4.1-like protein 5

1

0

High-throughput

0.513

High

1452208

PA2GE
Group IIE secretory phospholipase A2

1

0

High-throughput

0.513

High

443539

CDK1
Cyclin-dependent kinase 1

1

0

Small-scale

0.480

High

167981

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

1

Small-scale

0.479

High

177953

IKKA
Inhibitor of nuclear factor kappa-B kinase subunit alpha

1

1

Small-scale

0.479

High

755803

MCM4
DNA replication licensing factor MCM4

1

2

High-throughput

0.479

High

888351

MCM2
DNA replication licensing factor MCM2

1

2

High-throughput

0.479

High

1116060

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

1

High-throughput

0.479

High

1128296

MCM6
DNA replication licensing factor MCM6

1

2

High-throughput

0.479

High

1205190

CT451
Cancer/testis antigen family 45 member A1

1

3

High-throughput

0.479

High

194371

R113A
E3 ubiquitin-protein ligase RNF113A

1

0

High-throughput

0.458

High

244022

JIP4
C-Jun-amino-terminal kinase-interacting protein 4

1

0

High-throughput

0.458

High

260543

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

719183

MPIP1
M-phase inducer phosphatase 1

1

0

High-throughput

0.458

High

944577

GEMI4
Gem-associated protein 4

1

0

Small-scale

0.458

High

957528

UBC12
NEDD8-conjugating enzyme Ubc12

1

0

High-throughput

0.458

High

995851

ACTC
Actin, alpha cardiac muscle 1

1

0

High-throughput

0.458

High

1255828

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1329908

SIR6
NAD-dependent protein deacylase sirtuin-6

1

0

High-throughput

0.458

High

1404461

CDC5L
Cell division cycle 5-like protein

1

0

High-throughput

0.458

High

1452210

DDX20
Probable ATP-dependent RNA helicase DDX20

1

0

Small-scale

0.458

High

1452212

FZR1
Fizzy-related protein homolog

1

0

High-throughput

0.458

High

1452214

SRRM2
Serine/arginine repetitive matrix protein 2

1

0

High-throughput

0.458

High

1452216

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

0

High-throughput

0.458

High

139146

KRIT1
Krev interaction trapped protein 1

1

0

High-throughput

0.426

High

298104

SPF27
Pre-mRNA-splicing factor SPF27

1

0

High-throughput

0.426

High

1387410

ESS2
Splicing factor ESS-2 homolog

1

0

High-throughput

0.426

High

1412852

CCM2
Cerebral cavernous malformations 2 protein

1

0

High-throughput

0.426

High

1446244

UBE2T
Ubiquitin-conjugating enzyme E2 T

1

0

High-throughput

0.426

High

1452209

LMCD1
LIM and cysteine-rich domains protein 1

1

0

High-throughput

0.426

High

516133

CT456
Cancer/testis antigen family 45 member A6

1

3

High-throughput

0.407

High

516147

CT459
Cancer/testis antigen family 45 member A9

1

3

High-throughput

0.407

High

887269

CEBPA
CCAAT/enhancer-binding protein alpha

1

0

High-throughput

0.391

High

289889

TIPRL
TIP41-like protein

6

0

Small-scale

0.383

High

1156605

CCDC6
Coiled-coil domain-containing protein 6

4

0

High-throughput

0.360

High

1279030

TAFA3
Chemokine-like protein TAFA-3

2

0

High-throughput

0.328

High

66315

MET15
12S rRNA N(4)-cytidine methyltransferase METTL15

1

0

High-throughput

0.279

Low

282111

MPPB
Mitochondrial-processing peptidase subunit beta

1

0

High-throughput

0.279

Low

884249

SRP09
Signal recognition particle 9 kDa protein

1

0

High-throughput

0.279

Low

1203550

F133B
Protein FAM133B

1

0

High-throughput

0.279

Low

229827

CALU
Calumenin

1

0

High-throughput

0.249

Low

1226542

DCA15
DDB1- and CUL4-associated factor 15

1

0

High-throughput

0.249

Low

1291697

CMTD1
Catechol O-methyltransferase domain-containing protein 1

1

0

High-throughput

0.249

Low

1396834

SNX27
Sorting nexin-27

1

0

High-throughput

0.249

Low

1397084

UBX10
UBX domain-containing protein 10

1

0

High-throughput

0.249

Low

1279095

RIC3
Protein RIC-3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025