Protein: BC11A
BCL11 transcription factor A (B-cell CLL/lymphoma 11A) (B-cell lymphoma/leukemia 11A) (BCL-11A) (COUP-TF-interacting protein 1) (Ecotropic viral integration site 9 protein homolog) (EVI-9) (Zinc finger protein 856)

Gene: BC11A, BCL11A
Organism: Homo sapiens
Interactions: 108
UniProt ID: Q9H165

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001067 - transcription regulatory region nucleic acid binding
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0003700 - DNA-binding transcription factor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

832801

BCL6
B-cell lymphoma 6 protein

2

16

Small-scale

0.825

High

1421342

BC11B
B-cell lymphoma/leukemia 11B

2

11

High-throughput

0.789

High

1430821

BC11A
BCL11 transcription factor A

2

10

Small-scale

0.768

High

208897

ZBT24
Zinc finger and BTB domain-containing protein 24

1

17

High-throughput

0.740

High

1110065

HDAC1
Histone deacetylase 1

6

7

Small-scale

0.737

High

1158999

RBBP7
Histone-binding protein RBBP7

6

6

Small-scale

0.733

High

1102648

MTA1
Metastasis-associated protein MTA1

6

6

Small-scale

0.732

High

1066487

RBBP4
Histone-binding protein RBBP4

5

6

Small-scale

0.722

High

549235

CDK4
Cyclin-dependent kinase 4

1

3

Small-scale

0.710

High

1025424

CDK6
Cyclin-dependent kinase 6

1

3

Small-scale

0.710

High

1368111

HDAC2
Histone deacetylase 2

4

7

Small-scale

0.696

High

1132968

CHD4
Chromodomain-helicase-DNA-binding protein 4

4

10

Small-scale

0.676

High

222201

NCK2
Cytoplasmic protein NCK2

3

4

High-throughput

0.675

High

1359982

MB3L1
Methyl-CpG-binding domain protein 3-like 1

3

8

High-throughput

0.667

High

1430830

NR2E1
Nuclear receptor subfamily 2 group E member 1

2

14

Small-scale

0.649

High

316983

MTA2
Metastasis-associated protein MTA2

3

6

Small-scale

0.646

High

1365054

UBXN4
UBX domain-containing protein 4

3

0

High-throughput

0.638

High

641255

FGFR2
Fibroblast growth factor receptor 2

2

2

High-throughput

0.628

High

522835

COT1
COUP transcription factor 1

2

16

Small-scale

0.622

High

538468

EGR2
E3 SUMO-protein ligase EGR2

1

19

High-throughput

0.618

High

944737

KLF3
Krueppel-like factor 3

1

18

High-throughput

0.618

High

1328948

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

17

High-throughput

0.618

High

1357125

ZN296
Zinc finger protein 296

1

15

High-throughput

0.618

High

1396128

Z512B
Zinc finger protein 512B

1

12

High-throughput

0.618

High

1430825

ZN219
Zinc finger protein 219

1

9

High-throughput

0.618

High

71472

P20L1
PHD finger protein 20-like protein 1

2

1

High-throughput

0.611

High

1155752

EZH2
Histone-lysine N-methyltransferase EZH2

2

1

Small-scale

0.595

High

1403016

SIN3A
Paired amphipathic helix protein Sin3a

2

1

Small-scale

0.595

High

352243

MBD3
Methyl-CpG-binding domain protein 3

2

8

Small-scale

0.584

High

1088560

CHD3
Chromodomain-helicase-DNA-binding protein 3

2

10

High-throughput

0.584

High

1109385

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

2

0

High-throughput

0.580

High

1136855

MO4L2
Mortality factor 4-like protein 2

2

0

High-throughput

0.580

High

665140

COT2
COUP transcription factor 2

1

12

Small-scale

0.573

High

1430832

NR2E3
Photoreceptor-specific nuclear receptor

1

10

Small-scale

0.573

High

682101

RBTN1
Rhombotin-1

1

4

High-throughput

0.573

High

1137518

SUZ12
Polycomb protein SUZ12

2

0

Small-scale

0.569

High

1388726

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

5

Small-scale

0.561

High

900504

FXR2
RNA-binding protein FXR2

1

8

High-throughput

0.541

High

995812

ACTC
Actin, alpha cardiac muscle 1

1

2

High-throughput

0.541

High

1364989

TSC1
Hamartin

1

8

High-throughput

0.541

High

166190

AIM2
Interferon-inducible protein AIM2

1

1

High-throughput

0.536

High

1340905

MB3L2
Methyl-CpG-binding domain protein 3-like 2

1

8

High-throughput

0.536

High

1430824

M3K20
Mitogen-activated protein kinase kinase kinase 20

1

4

High-throughput

0.536

High

1405943

CDCA3
Cell division cycle-associated protein 3

1

0

High-throughput

0.518

High

1337281

GMCL2
Germ cell-less protein-like 2

1

2

High-throughput

0.515

High

423137

A4
Amyloid-beta precursor protein

1

10

High-throughput

0.501

High

993740

UBC9
SUMO-conjugating enzyme UBC9

1

1

Small-scale

0.501

High

1430829

G3BP2
Ras GTPase-activating protein-binding protein 2

1

1

High-throughput

0.501

High

522793

NR2F6
Nuclear receptor subfamily 2 group F member 6

1

15

Small-scale

0.481

High

1026219

CLH1
Clathrin heavy chain 1

1

0

High-throughput

0.480

High

143245

NFIB
Nuclear factor 1 B-type

1

14

High-throughput

0.479

High

155352

CDKA1
Cyclin-dependent kinase 2-associated protein 1

1

4

High-throughput

0.479

High

210346

PHF1
PHD finger protein 1

1

1

High-throughput

0.479

High

243731

SMCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

1

11

High-throughput

0.479

High

274380

SIN3B
Paired amphipathic helix protein Sin3b

1

1

High-throughput

0.479

High

282307

SAP30
Histone deacetylase complex subunit SAP30

1

2

High-throughput

0.479

High

299491

CDKA2
Cyclin-dependent kinase 2-associated protein 2

1

4

Small-scale

0.479

High

474278

NFIC
Nuclear factor 1 C-type

1

14

High-throughput

0.479

High

519563

MYBB
Myb-related protein B

1

4

High-throughput

0.479

High

582953

EZRI
Ezrin

1

1

High-throughput

0.479

High

659299

SP100
Nuclear autoantigen Sp-100

1

3

High-throughput

0.479

High

703376

SMCA1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1

1

11

High-throughput

0.479

High

800095

COIL
Coilin

1

3

High-throughput

0.479

High

887211

CEBPA
CCAAT/enhancer-binding protein alpha

1

6

High-throughput

0.479

High

938502

PAX9
Paired box protein Pax-9

1

1

High-throughput

0.479

High

942464

GSC
Homeobox protein goosecoid

1

5

High-throughput

0.479

High

1063609

GOGA2
Golgin subfamily A member 2

1

8

High-throughput

0.479

High

1086817

BPTF
Nucleosome-remodeling factor subunit BPTF

1

13

High-throughput

0.479

High

1088006

NFIA
Nuclear factor 1 A-type

1

15

High-throughput

0.479

High

1114265

CUL3
Cullin-3

1

20

High-throughput

0.479

High

1133652

NFIX
Nuclear factor 1 X-type

1

15

High-throughput

0.479

High

1135276

SHPRH
E3 ubiquitin-protein ligase SHPRH

1

13

High-throughput

0.479

High

1195600

ARI4B
AT-rich interactive domain-containing protein 4B

1

4

High-throughput

0.479

High

1198003

LIN52
Protein lin-52 homolog

1

1

High-throughput

0.479

High

1208644

BRM1L
Breast cancer metastasis-suppressor 1-like protein

1

4

High-throughput

0.479

High

1216629

LIN9
Protein lin-9 homolog

1

2

High-throughput

0.479

High

1295303

P66A
Transcriptional repressor p66-alpha

1

3

High-throughput

0.479

High

1312691

BAP18
BPTF-associated chromatin complex component 1

1

2

High-throughput

0.479

High

1351287

CHD5
Chromodomain-helicase-DNA-binding protein 5

1

10

High-throughput

0.479

High

1361006

P66B
Transcriptional repressor p66-beta

1

3

High-throughput

0.479

High

1392570

LIN37
Protein lin-37 homolog

1

2

High-throughput

0.479

High

1398770

PWP2A
PWWP domain-containing protein 2A

1

2

High-throughput

0.479

High

1401048

PHF12
PHD finger protein 12

1

18

High-throughput

0.479

High

1413340

MTA3
Metastasis-associated protein MTA3

1

6

High-throughput

0.479

High

1429904

SP130
Histone deacetylase complex subunit SAP130

1

4

High-throughput

0.479

High

1430822

SDS3
Sin3 histone deacetylase corepressor complex component SDS3

1

4

High-throughput

0.479

High

1430826

MBD2
Methyl-CpG-binding domain protein 2

1

8

High-throughput

0.479

High

1430828

ZMYD8
MYND-type zinc finger-containing chromatin reader ZMYND8

1

11

High-throughput

0.479

High

1430831

MTF2
Metal-response element-binding transcription factor 2

1

1

High-throughput

0.479

High

130610

SPT5H
Transcription elongation factor SPT5

1

0

High-throughput

0.458

High

168323

HAT1
Histone acetyltransferase type B catalytic subunit

1

0

High-throughput

0.458

High

285469

EED
Polycomb protein EED

1

0

High-throughput

0.458

High

487741

PARP1
Poly [ADP-ribose] polymerase 1

1

0

High-throughput

0.458

High

1094733

CAF1A
Chromatin assembly factor 1 subunit A

1

0

High-throughput

0.458

High

1094811

CAF1B
Chromatin assembly factor 1 subunit B

1

0

High-throughput

0.458

High

1244828

FBX38
F-box only protein 38

1

0

High-throughput

0.458

High

1357151

GATD1
GATA zinc finger domain-containing protein 1

1

0

High-throughput

0.458

High

1405431

FEV
Protein FEV

1

0

High-throughput

0.458

High

1420459

DPY30
Protein dpy-30 homolog

1

0

High-throughput

0.458

High

1428615

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

0

High-throughput

0.458

High

1430833

PIAS3
E3 SUMO-protein ligase PIAS3

1

0

Small-scale

0.458

High

1430827

HMGX4
HMG domain-containing protein 4

1

9

High-throughput

0.437

High

1352981

CE192
Centrosomal protein of 192 kDa

1

0

High-throughput

0.426

High

1337782

NFAM1
NFAT activation molecule 1

2

0

High-throughput

0.316

High

1403722

YMEL1
ATP-dependent zinc metalloprotease YME1L1

1

0

High-throughput

0.282

High

1383669

VP33A
Vacuolar protein sorting-associated protein 33A

1

0

High-throughput

0.249

Low

1430823

RM22
Large ribosomal subunit protein uL22m

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025