Protein: SYNCI
Syncoilin (Syncoilin intermediate filament 1) (Syncoilin-1)

Gene: SYNCI, SYNC
Organism: Homo sapiens
Interactions: 69
UniProt ID: Q9H7C4

Gene Ontology (top 5):
GO:0005829 - cytosol
GO:0005882 - intermediate filament
GO:0030018 - Z disc
GO:0031594 - neuromuscular junction
GO:0042383 - sarcolemma

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

474990

VIME
Vimentin

5

20

High-throughput

0.934

High

606159

DESM
Desmin

3

20

Small-scale

0.877

High

451272

NFL
Neurofilament light polypeptide

3

20

High-throughput

0.866

High

570601

GFAP
Glial fibrillary acidic protein

3

19

High-throughput

0.866

High

176368

SYNEM
Synemin

2

20

High-throughput

0.811

High

451449

NFM
Neurofilament medium polypeptide

2

20

High-throughput

0.811

High

833366

PERI
Peripherin

2

20

High-throughput

0.811

High

1157257

AINX
Alpha-internexin

2

20

High-throughput

0.811

High

385177

K1C14
Keratin, type I cytoskeletal 14

1

20

High-throughput

0.691

High

386237

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

20

High-throughput

0.691

High

476395

K1C16
Keratin, type I cytoskeletal 16

1

20

High-throughput

0.691

High

876642

NEST
Nestin

1

20

High-throughput

0.691

High

1277639

K1C27
Keratin, type I cytoskeletal 27

1

20

High-throughput

0.691

High

1420602

K1C23
Keratin, type I cytoskeletal 23

1

20

High-throughput

0.691

High

164097

NDC80
Kinetochore protein NDC80 homolog

2

20

High-throughput

0.628

High

214037

M3K7
Mitogen-activated protein kinase kinase kinase 7

2

1

High-throughput

0.628

High

659590

CRCM
Colorectal mutant cancer protein

2

4

High-throughput

0.628

High

668716

APC
Adenomatous polyposis coli protein

2

9

High-throughput

0.628

High

1063180

GOGA3
Golgin subfamily A member 3

2

11

High-throughput

0.628

High

1095804

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

2

20

High-throughput

0.628

High

1121984

ARHG7
Rho guanine nucleotide exchange factor 7

2

7

High-throughput

0.628

High

1135383

SLMAP
Sarcolemmal membrane-associated protein

2

7

High-throughput

0.628

High

1138066

TNIP1
TNFAIP3-interacting protein 1

2

13

High-throughput

0.628

High

1140200

ARHG6
Rho guanine nucleotide exchange factor 6

2

8

High-throughput

0.628

High

1144879

RABE1
Rab GTPase-binding effector protein 1

2

5

High-throughput

0.628

High

1153116

TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

2

1

High-throughput

0.628

High

1310170

GCC2
GRIP and coiled-coil domain-containing protein 2

2

10

High-throughput

0.628

High

1403342

RUFY1
RUN and FYVE domain-containing protein 1

2

13

High-throughput

0.628

High

1414960

CP250
Centrosome-associated protein CEP250

2

12

High-throughput

0.628

High

1419858

UACA
Uveal autoantigen with coiled-coil domains and ankyrin repeats

2

10

High-throughput

0.628

High

1431652

GAN
Gigaxonin

2

15

High-throughput

0.628

High

1435636

KIF15
Kinesin-like protein KIF15

2

4

High-throughput

0.628

High

1435639

GIT1
ARF GTPase-activating protein GIT1

2

4

High-throughput

0.628

High

1435640

NEMO
NF-kappa-B essential modulator

2

15

High-throughput

0.628

High

1389075

THA11
THAP domain-containing protein 11

2

0

High-throughput

0.602

High

1122442

GIT2
ARF GTPase-activating protein GIT2

2

6

High-throughput

0.574

High

1198526

CEP55
Centrosomal protein of 55 kDa

2

1

High-throughput

0.574

High

1206654

TJAP1
Tight junction-associated protein 1

2

1

High-throughput

0.574

High

1242396

GOLM2
Protein GOLM2

2

1

High-throughput

0.574

High

1348325

GOGA5
Golgin subfamily A member 5

2

18

High-throughput

0.574

High

1381923

C102A
Coiled-coil domain-containing protein 102A

2

2

High-throughput

0.574

High

1395348

CC136
Coiled-coil domain-containing protein 136

2

16

High-throughput

0.574

High

1154171

ITSN1
Intersectin-1

1

20

High-throughput

0.541

High

248781

PEPL
Periplakin

1

20

High-throughput

0.536

High

540091

BCR
Breakpoint cluster region protein

1

16

High-throughput

0.536

High

839826

EPS15
Epidermal growth factor receptor substrate 15

1

16

High-throughput

0.536

High

1353046

GEMI5
Gem-associated protein 5

1

11

High-throughput

0.536

High

1388642

SPDLY
Protein Spindly

1

12

High-throughput

0.536

High

1401993

GCP5
Gamma-tubulin complex component 5

1

7

High-throughput

0.536

High

1415384

DUS23
Dual specificity protein phosphatase 23

1

1

High-throughput

0.536

High

1435635

MAGE1
Melanoma-associated antigen E1

1

5

High-throughput

0.536

High

1435638

KLH42
Kelch-like protein 42

1

5

High-throughput

0.536

High

593791

PECA1
Platelet endothelial cell adhesion molecule

1

10

High-throughput

0.515

High

631480

RAB5A
Ras-related protein Rab-5A

1

2

High-throughput

0.515

High

996539

ACTS
Actin, alpha skeletal muscle

1

2

High-throughput

0.515

High

1435637

FGOP2
FGFR1 oncogene partner 2

1

0

High-throughput

0.513

High

1103796

PLD1
Phospholipase D1

1

0

High-throughput

0.493

High

50141

BICL2
BICD family-like cargo adapter 2

1

20

High-throughput

0.489

High

1316553

MAML2
Mastermind-like protein 2

1

15

High-throughput

0.489

High

1390820

CPNE2
Copine-2

1

1

High-throughput

0.489

High

1067721

EP300
Histone acetyltransferase p300

1

2

High-throughput

0.479

High

1220802

RN123
E3 ubiquitin-protein ligase RNF123

1

5

High-throughput

0.479

High

246138

KIF1B
Kinesin-like protein KIF1B

1

7

High-throughput

0.470

High

301703

WFS1
Wolframin

1

1

High-throughput

0.470

High

565711

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

1

High-throughput

0.470

High

1351588

MIPT3
TRAF3-interacting protein 1

1

1

High-throughput

0.417

High

1432189

IPYR2
Inorganic pyrophosphatase 2, mitochondrial

2

0

High-throughput

0.328

High

1219891

OBI1
ORC ubiquitin ligase 1

1

0

High-throughput

0.279

Low

963021

CH10
10 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.269

Low


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Last updated: 11Aug2025