Protein: UTP23
rRNA-processing protein UTP23 homolog

Gene: UTP23
Organism: Homo sapiens
Interactions: 212
UniProt ID: Q9BRU9

Gene Ontology (top 5):
GO:0000480 - endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003723 - RNA binding
GO:0003730 - mRNA 3'-UTR binding
GO:0005730 - nucleolus
GO:0032040 - small-subunit processome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

476794

RSSA
Small ribosomal subunit protein uS2

3

2

High-throughput

0.667

High

1348841

ZCRB1
Zinc finger CCHC-type and RNA-binding motif-containing protein 1

3

1

High-throughput

0.662

High

1411918

FCF1
rRNA-processing protein FCF1 homolog

1

2

Small-scale

0.647

High

517697

ZBT48
Zinc finger and BTB domain-containing protein 48

2

1

High-throughput

0.628

High

612759

RL7
Large ribosomal subunit protein uL30

2

1

High-throughput

0.628

High

950645

KR108
Keratin-associated protein 10-8

3

5

High-throughput

0.616

High

586861

RS2
Small ribosomal subunit protein uS5

2

2

High-throughput

0.611

High

1037341

H11
Histone H1.1

3

6

High-throughput

0.609

High

961825

RL37A
Large ribosomal subunit protein eL43

2

0

High-throughput

0.602

High

809814

RS19
Small ribosomal subunit protein eS19

2

2

High-throughput

0.601

High

860917

RS10
Small ribosomal subunit protein eS10

2

2

High-throughput

0.601

High

984943

RL31
Large ribosomal subunit protein eL31

2

2

High-throughput

0.601

High

1112149

KRR1
KRR1 small subunit processome component homolog

2

2

High-throughput

0.601

High

1332220

KRI1
Protein KRI1 homolog

2

1

High-throughput

0.601

High

1411906

ZN346
Zinc finger protein 346

2

2

High-throughput

0.601

High

1411916

YBOX2
Y-box-binding protein 2

2

4

High-throughput

0.601

High

705533

GRN
Progranulin

2

0

High-throughput

0.580

High

1277373

NT2NA
Notch homolog 2 N-terminal-like protein A

2

2

High-throughput

0.578

High

572168

TRI27
Zinc finger protein RFP

1

1

High-throughput

0.573

High

1411910

RL26L
Ribosomal protein uL24-like

2

1

High-throughput

0.571

High

300479

KRT34
Keratin, type I cuticular Ha4

2

3

High-throughput

0.553

High

300827

KRT38
Keratin, type I cuticular Ha8

2

3

High-throughput

0.553

High

1063573

GOGA2
Golgin subfamily A member 2

2

2

High-throughput

0.553

High

1090885

TRAF2
TNF receptor-associated factor 2

2

2

High-throughput

0.553

High

1307441

KRA13
Keratin-associated protein 1-3

2

5

High-throughput

0.553

High

1341228

IKBD
NF-kappa-B inhibitor delta

2

2

High-throughput

0.553

High

423007

A4
Amyloid-beta precursor protein

2

2

High-throughput

0.550

High

208359

RRP8
Ribosomal RNA-processing protein 8

1

1

High-throughput

0.536

High

228744

U3IP2
U3 small nucleolar RNA-interacting protein 2

1

1

High-throughput

0.536

High

257952

DKC1
H/ACA ribonucleoprotein complex subunit DKC1

1

1

High-throughput

0.536

High

274230

ANR17
Ankyrin repeat domain-containing protein 17

1

1

High-throughput

0.536

High

287113

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

1

5

High-throughput

0.536

High

290702

SURF6
Surfeit locus protein 6

1

1

High-throughput

0.536

High

301187

RL1D1
Ribosomal L1 domain-containing protein 1

1

1

High-throughput

0.536

High

346257

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

5

High-throughput

0.536

High

350973

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

1

2

High-throughput

0.536

High

521901

H14
Histone H1.4

1

6

High-throughput

0.536

High

595579

H15
Histone H1.5

1

6

High-throughput

0.536

High

595860

H13
Histone H1.3

1

6

High-throughput

0.536

High

596323

H12
Histone H1.2

1

6

High-throughput

0.536

High

599871

YBOX3
Y-box-binding protein 3

1

4

High-throughput

0.536

High

686381

RL13
Large ribosomal subunit protein eL13

1

1

High-throughput

0.536

High

785406

RL4
Large ribosomal subunit protein uL4

1

2

High-throughput

0.536

High

824321

RL13A
Large ribosomal subunit protein uL13

1

1

High-throughput

0.536

High

842503

RL35
Large ribosomal subunit protein uL29

1

1

High-throughput

0.536

High

860599

RS5
Small ribosomal subunit protein uS7

1

1

High-throughput

0.536

High

886573

CTCF
Transcriptional repressor CTCF

1

1

High-throughput

0.536

High

905084

MECP2
Methyl-CpG-binding protein 2

1

1

High-throughput

0.536

High

959933

RS3A
Small ribosomal subunit protein eS1

1

2

High-throughput

0.536

High

969399

RS8
Small ribosomal subunit protein eS8

1

2

High-throughput

0.536

High

973287

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.536

High

985849

RL11
Large ribosomal subunit protein uL5

1

2

High-throughput

0.536

High

986177

RL8
Large ribosomal subunit protein uL2

1

1

High-throughput

0.536

High

994760

YBOX1
Y-box-binding protein 1

1

4

High-throughput

0.536

High

1006664

SRPK2
SRSF protein kinase 2

1

2

High-throughput

0.536

High

1016589

SRSF3
Serine/arginine-rich splicing factor 3

1

5

High-throughput

0.536

High

1027706

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

2

High-throughput

0.536

High

1057877

RL18
Large ribosomal subunit protein eL18

1

1

High-throughput

0.536

High

1094092

RM28
Large ribosomal subunit protein bL28m

1

1

High-throughput

0.536

High

1099507

SRSF6
Serine/arginine-rich splicing factor 6

1

6

High-throughput

0.536

High

1194338

LARP7
La-related protein 7

1

1

High-throughput

0.536

High

1252506

LN28B
Protein lin-28 homolog B

1

5

High-throughput

0.536

High

1280453

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

1

High-throughput

0.536

High

1311389

ANKH1
Ankyrin repeat and KH domain-containing protein 1

1

1

High-throughput

0.536

High

1327377

ZCHC9
Zinc finger CCHC domain-containing protein 9

1

3

High-throughput

0.536

High

1336625

PAPD5
Terminal nucleotidyltransferase 4B

1

1

High-throughput

0.536

High

1340450

DDX55
ATP-dependent RNA helicase DDX55

1

5

High-throughput

0.536

High

1351457

BRX1
Ribosome biogenesis protein BRX1 homolog

1

3

High-throughput

0.536

High

1360398

SRS12
Serine/arginine-rich splicing factor 12

1

1

High-throughput

0.536

High

1361745

DGCR8
Microprocessor complex subunit DGCR8

1

1

High-throughput

0.536

High

1392223

DDX27
Probable ATP-dependent RNA helicase DDX27

1

1

High-throughput

0.536

High

1396344

ZFR
Zinc finger RNA-binding protein

1

1

High-throughput

0.536

High

1400964

PURB
Transcriptional regulator protein Pur-beta

1

1

High-throughput

0.536

High

1402765

STRBP
Spermatid perinuclear RNA-binding protein

1

4

High-throughput

0.536

High

1405185

MPP8
M-phase phosphoprotein 8

1

2

High-throughput

0.536

High

1411885

RBM4
RNA-binding protein 4

1

1

High-throughput

0.536

High

1411895

DDX18
ATP-dependent RNA helicase DDX18

1

6

High-throughput

0.536

High

1411896

RBM28
RNA-binding protein 28

1

1

High-throughput

0.536

High

1411903

BAZ1B
Tyrosine-protein kinase BAZ1B

1

1

High-throughput

0.536

High

1411905

PURG
Purine-rich element-binding protein gamma

1

1

High-throughput

0.536

High

1411914

RT07
Small ribosomal subunit protein uS7m

1

1

High-throughput

0.536

High

1411921

RBM19
Probable RNA-binding protein 19

1

1

High-throughput

0.536

High

950874

KR109
Keratin-associated protein 10-9

1

6

High-throughput

0.523

High

1146126

K1H1
Keratin, type I cuticular Ha1

1

3

High-throughput

0.523

High

1230226

K1C40
Keratin, type I cytoskeletal 40

1

3

High-throughput

0.523

High

1411904

TRIM1
Probable E3 ubiquitin-protein ligase MID2

1

3

High-throughput

0.523

High

396831

ESR1
Estrogen receptor

2

1

High-throughput

0.521

High

243721

SMCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

1

0

High-throughput

0.513

High

271090

PTCD1
Pentatricopeptide repeat-containing protein 1, mitochondrial

1

0

High-throughput

0.513

High

286050

SF3B1
Splicing factor 3B subunit 1

1

0

High-throughput

0.513

High

338179

NSA2
Ribosome biogenesis protein NSA2 homolog

1

0

High-throughput

0.513

High

355591

NSD2
Histone-lysine N-methyltransferase NSD2

1

0

High-throughput

0.513

High

428945

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.513

High

485721

RU2A
U2 small nuclear ribonucleoprotein A'

1

0

High-throughput

0.513

High

604728

UBF1
Nucleolar transcription factor 1

1

0

High-throughput

0.513

High

620555

NUCL
Nucleolin

1

0

High-throughput

0.513

High

693941

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.513

High

841443

RBM34
RNA-binding protein 34

1

0

High-throughput

0.513

High

855195

NOP2
28S rRNA

1

0

High-throughput

0.513

High

983337

RS28
Small ribosomal subunit protein eS28

1

0

High-throughput

0.513

High

1009301

PRR3
Proline-rich protein 3

1

0

High-throughput

0.513

High

1016190

RL19
Large ribosomal subunit protein eL19

1

0

High-throughput

0.513

High

1039367

RL6
Large ribosomal subunit protein eL6

1

0

High-throughput

0.513

High

1043739

CEBPZ
CCAAT/enhancer-binding protein zeta

1

0

High-throughput

0.513

High

1062620

DHX9
ATP-dependent RNA helicase A

1

0

High-throughput

0.513

High

1105398

SF3B2
Splicing factor 3B subunit 2

1

0

High-throughput

0.513

High

1146525

TTF1
Transcription termination factor 1

1

0

High-throughput

0.513

High

1148152

PUM3
Pumilio homolog 3

1

0

High-throughput

0.513

High

1199365

GLE1
mRNA export factor GLE1

1

0

High-throughput

0.513

High

1212086

SPOUT
28S rRNA

1

0

High-throughput

0.513

High

1271823

MEPCE
7SK snRNA methylphosphate capping enzyme

1

0

High-throughput

0.513

High

1275642

ZCCHV
Zinc finger CCCH-type antiviral protein 1

1

0

High-throughput

0.513

High

1314224

SPB1
pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3

1

0

High-throughput

0.513

High

1392101

TOE1
Target of EGR1 protein 1

1

0

High-throughput

0.513

High

1410204

CMS1
Protein CMSS1

1

0

High-throughput

0.513

High

1411886

MAK16
Protein MAK16 homolog

1

0

High-throughput

0.513

High

1411887

GTPB4
GTP-binding protein 4

1

0

High-throughput

0.513

High

1411888

REXO4
RNA exonuclease 4

1

0

High-throughput

0.513

High

1411892

RT30
Large ribosomal subunit protein mL65

1

0

High-throughput

0.513

High

1411893

SSF1
Suppressor of SWI4 1 homolog

1

0

High-throughput

0.513

High

1411897

PK1IP
p21-activated protein kinase-interacting protein 1

1

0

High-throughput

0.513

High

1411899

LYAR
Cell growth-regulating nucleolar protein

1

0

High-throughput

0.513

High

1411902

DAXX
Death domain-associated protein 6

1

0

High-throughput

0.513

High

1411912

RT28
Small ribosomal subunit protein bS1m

1

0

High-throughput

0.513

High

1411920

RT18C
Small ribosomal subunit protein bS18m

1

0

High-throughput

0.513

High

1411898

NHP2
H/ACA ribonucleoprotein complex subunit 2

1

2

Small-scale

0.501

High

1411913

DDX52
Probable ATP-dependent RNA helicase DDX52

1

3

Small-scale

0.501

High

1411919

RRP7A
Ribosomal RNA-processing protein 7 homolog A

1

2

Small-scale

0.501

High

191782

MAGB2
Melanoma-associated antigen B2

1

1

High-throughput

0.489

High

338946

CBX6
Chromobox protein homolog 6

1

2

High-throughput

0.489

High

419175

H2A1B
Histone H2A type 1-B/E

1

1

High-throughput

0.489

High

649407

H1T
Histone H1t

1

6

High-throughput

0.489

High

1089262

TRI26
Tripartite motif-containing protein 26

1

1

High-throughput

0.489

High

1127475

FGFP1
Fibroblast growth factor-binding protein 1

1

1

High-throughput

0.489

High

1238042

ZSC25
Zinc finger and SCAN domain-containing protein 25

1

1

High-throughput

0.489

High

1307311

H2A2B
Histone H2A type 2-B

1

1

High-throughput

0.489

High

1313132

ZC3H3
Zinc finger CCCH domain-containing protein 3

1

2

High-throughput

0.489

High

1398060

ZN512
Zinc finger protein 512

1

1

High-throughput

0.489

High

1411901

ZNF70
Zinc finger protein 70

1

1

High-throughput

0.489

High

1411907

ZN777
Zinc finger protein 777

1

1

High-throughput

0.489

High

96754

E9PAV9
G patch domain-containing protein 4

1

3

High-throughput

0.479

High

373000

MYC
Myc proto-oncogene protein

1

2

High-throughput

0.479

High

406574

MYCN
N-myc proto-oncogene protein

1

2

High-throughput

0.479

High

810328

RL3
Large ribosomal subunit protein uL3

1

1

High-throughput

0.479

High

979185

RS6
Small ribosomal subunit protein eS6

1

1

High-throughput

0.479

High

1411900

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

1

High-throughput

0.479

High

517092

NT2NC
Notch homolog 2 N-terminal-like protein C

1

2

High-throughput

0.470

High

950116

KR105
Keratin-associated protein 10-5

1

6

High-throughput

0.470

High

1232545

Q6FHY5
MEOX2 protein

1

1

High-throughput

0.470

High

340528

ZBT11
Zinc finger and BTB domain-containing protein 11

1

1

High-throughput

0.445

High

447372

NPM
Nucleophosmin

1

1

High-throughput

0.445

High

1004393

NOP14
Nucleolar protein 14

1

1

High-throughput

0.445

High

1208801

TDIF2
Deoxynucleotidyltransferase terminal-interacting protein 2

1

1

High-throughput

0.445

High

1212364

GPTC4
G patch domain-containing protein 4

1

3

High-throughput

0.445

High

1214666

RBM26
RNA-binding protein 26

1

1

High-throughput

0.445

High

1219427

TUT7
Terminal uridylyltransferase 7

1

1

High-throughput

0.445

High

1334844

SERB1
SERPINE1 mRNA-binding protein 1

1

1

High-throughput

0.445

High

1411536

PYM1
Partner of Y14 and mago

1

1

High-throughput

0.445

High

1411882

TRI56
E3 ubiquitin-protein ligase TRIM56

1

3

High-throughput

0.445

High

1411884

UT14A
U3 small nucleolar RNA-associated protein 14 homolog A

1

1

High-throughput

0.445

High

1411908

ZMYD8
MYND-type zinc finger-containing chromatin reader ZMYND8

1

1

High-throughput

0.445

High

1411911

ZC3H4
Zinc finger CCCH domain-containing protein 4

1

2

High-throughput

0.445

High

611

NBPFJ
NBPF family member NBPF19

1

2

High-throughput

0.439

High

894124

MEOX2
Homeobox protein MOX-2

1

1

High-throughput

0.439

High

949979

KR103
Keratin-associated protein 10-3

1

6

High-throughput

0.439

High

879408

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

1

High-throughput

0.437

High

1137993

TNIP1
TNFAIP3-interacting protein 1

1

3

High-throughput

0.437

High

1367142

ESR2
Estrogen receptor beta

1

1

High-throughput

0.437

High

601837

HMGA1
High mobility group protein HMG-I/HMG-Y

1

0

High-throughput

0.426

High

1032860

XPC
DNA repair protein complementing XP-C cells

1

0

High-throughput

0.426

High

1411883

MMTA2
Multiple myeloma tumor-associated protein 2

1

0

High-throughput

0.426

High

1411890

EAF6
Chromatin modification-related protein MEAF6

1

0

High-throughput

0.426

High

1411894

ABC3C
DNA dC->dU-editing enzyme APOBEC-3C

1

0

High-throughput

0.426

High

47562

RPSA2
Small ribosomal subunit protein uS2B

1

2

High-throughput

0.407

High

65280

ZN316
Zinc finger protein 316

1

1

High-throughput

0.407

High

1132231

CBX2
Chromobox protein homolog 2

1

2

High-throughput

0.407

High

1393155

PRR11
Proline-rich protein 11

3

0

High-throughput

0.347

High

70441

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.316

High

949616

KR123
Keratin-associated protein 12-3

2

0

High-throughput

0.316

High

1398694

AP4AT
AP-4 complex accessory subunit Tepsin

2

0

High-throughput

0.316

High

1402044

TRIB3
Tribbles homolog 3

2

0

High-throughput

0.316

High

303345

PDE9A
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A

1

0

High-throughput

0.299

High

587199

ITF2
Transcription factor 4

1

0

High-throughput

0.299

High

783394

TRI23
E3 ubiquitin-protein ligase TRIM23

1

0

High-throughput

0.299

High

76020

B4DEF8
Large ribosomal subunit protein mL45

1

0

High-throughput

0.279

Low

126179

AP3B1
AP-3 complex subunit beta-1

1

0

High-throughput

0.279

Low

334461

SYFM
Phenylalanine--tRNA ligase, mitochondrial

1

0

High-throughput

0.279

Low

376423

PDGFB
Platelet-derived growth factor subunit B

1

0

High-throughput

0.279

Low

428496

RLA2
Large ribosomal subunit protein P2

1

0

High-throughput

0.279

Low

674306

BRD2
Bromodomain-containing protein 2

1

0

High-throughput

0.279

Low

1029368

SET
Protein SET

1

0

High-throughput

0.279

Low

1132634

KIF22
Kinesin-like protein KIF22

1

0

High-throughput

0.279

Low

1135072

CUL7
Cullin-7

1

0

High-throughput

0.279

Low

1161377

HIF1A
Hypoxia-inducible factor 1-alpha

1

0

High-throughput

0.279

Low

1193372

GLYR1
Cytokine-like nuclear factor N-PAC

1

0

High-throughput

0.279

Low

1210519

HP1B3
Heterochromatin protein 1-binding protein 3

1

0

High-throughput

0.279

Low

1325519

FBXW8
F-box/WD repeat-containing protein 8

1

0

High-throughput

0.279

Low

1347053

G45IP
Large ribosomal subunit protein mL64

1

0

High-throughput

0.279

Low

1388382

MTEF3
Transcription termination factor 3, mitochondrial

1

0

High-throughput

0.279

Low

1406339

ZN184
Zinc finger protein 184

1

0

High-throughput

0.279

Low

1411891

NMNA1
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1

1

0

High-throughput

0.279

Low

1411915

AP3M1
AP-3 complex subunit mu-1

1

0

High-throughput

0.279

Low

978255

RHOB
Rho-related GTP-binding protein RhoB

1

0

High-throughput

0.249

Low

1108099

SQSTM
Sequestosome-1

1

0

High-throughput

0.249

Low

1380730

RL36L
Ribosomal protein eL42-like

1

0

High-throughput

0.249

Low

1411909

ALK
ALK tyrosine kinase receptor

1

0

High-throughput

0.249

Low

320355

PHF14
PHD finger protein 14

1

0

High-throughput

0.232

Low

388796

C1QC
Complement C1q subcomponent subunit C

1

0

High-throughput

0.232

Low

1206960

CEP78
Centrosomal protein of 78 kDa

1

0

High-throughput

0.232

Low

1219045

RSBN1
Lysine-specific demethylase 9

1

0

High-throughput

0.232

Low

1411889

ANKZ1
tRNA endonuclease ANKZF1

1

0

High-throughput

0.232

Low

1411917

ACOT9
Acyl-coenzyme A thioesterase 9, mitochondrial

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025