Protein: NCEH1
Neutral cholesterol ester hydrolase 1 (NCEH) (EC 3.1.1.-) (Acetylalkylglycerol acetylhydrolase) (2-acetyl MAGE hydrolase) (EC 3.1.1.71) (Arylacetamide deacetylase-like 1)

Gene: NCEH1
Organism: Homo sapiens
Interactions: 90
UniProt ID: Q6PIU2

Gene Ontology (top 5):
GO:0004771 - sterol ester esterase activity
GO:0005789 - endoplasmic reticulum membrane
GO:0005886 - plasma membrane
GO:0006805 - xenobiotic metabolic process
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

698777

CALX
Calnexin

3

2

High-throughput

0.675

High

1244872

TMTC3
Protein O-mannosyl-transferase TMTC3

3

1

High-throughput

0.662

High

332657

LYPD3
Ly6/PLAUR domain-containing protein 3

3

0

High-throughput

0.638

High

586185

CD1E
T-cell surface glycoprotein CD1e, membrane-associated

2

1

High-throughput

0.628

High

1164338

CGT
2-hydroxyacylsphingosine 1-beta-galactosyltransferase

2

1

High-throughput

0.628

High

1244917

SIA10
Type 2 lactosamine alpha-2,3-sialyltransferase

2

1

High-throughput

0.628

High

1116717

ITA7
Integrin alpha-7 [Cleaved into: Integrin alpha-7 heavy chain; Integrin alpha-7 light chain; Integrin alpha-7 70 kDa form]

2

0

High-throughput

0.602

High

1214088

DIK1A
Divergent protein kinase domain 1A

2

0

High-throughput

0.602

High

1244875

GALT7
N-acetylgalactosaminyltransferase 7

2

0

High-throughput

0.602

High

1244878

IPRI
Inositol 1,4,5-trisphosphate receptor-interacting protein

2

0

High-throughput

0.602

High

1244887

SCRB1
Scavenger receptor class B member 1

2

0

High-throughput

0.602

High

1244888

CANT1
Soluble calcium-activated nucleotidase 1

2

0

High-throughput

0.602

High

1244889

BT2A2
Butyrophilin subfamily 2 member A2

2

0

High-throughput

0.602

High

1244900

LMF2
Lipase maturation factor 2

2

0

High-throughput

0.602

High

1244902

LRRC3
Leucine-rich repeat-containing protein 3

2

0

High-throughput

0.602

High

1244906

ALG9
Alpha-1,2-mannosyltransferase ALG9

2

0

High-throughput

0.602

High

1244908

NRN1
Neuritin

2

0

High-throughput

0.602

High

1244911

E2AK3
Eukaryotic translation initiation factor 2-alpha kinase 3

2

0

High-throughput

0.602

High

1244916

CCPG1
Cell cycle progression protein 1

2

0

High-throughput

0.602

High

1244919

POMT1
Protein O-mannosyl-transferase 1

2

0

High-throughput

0.602

High

170815

CLGN
Calmegin

2

2

High-throughput

0.601

High

652843

EVI2A
Protein EVI2A

2

0

High-throughput

0.585

High

1244882

SERB1
SERPINE1 mRNA-binding protein 1

2

0

High-throughput

0.585

High

1244883

ZNRF1
E3 ubiquitin-protein ligase ZNRF1

2

0

High-throughput

0.585

High

299879

C1QRF
C1q-related factor

2

2

High-throughput

0.574

High

1187814

UD3A2
UDP-glucuronosyltransferase 3A2

2

1

High-throughput

0.574

High

1116995

LAMB3
Laminin subunit beta-3

2

3

High-throughput

0.549

High

164929

TR10C
Tumor necrosis factor receptor superfamily member 10C

1

2

High-throughput

0.536

High

209041

CYB5B
Cytochrome b5 type B

1

1

High-throughput

0.536

High

277018

ENTP6
Ectonucleoside triphosphate diphosphohydrolase 6

1

1

High-throughput

0.536

High

563935

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

High-throughput

0.536

High

1105485

OS9
Protein OS-9

1

1

High-throughput

0.536

High

1244881

ABD12
Lysophosphatidylserine lipase ABHD12

1

1

High-throughput

0.536

High

1244895

SGTB
Small glutamine-rich tetratricopeptide repeat-containing protein beta

1

2

High-throughput

0.536

High

1244901

T106C
Transmembrane protein 106C

1

1

High-throughput

0.536

High

1244918

NTNG1
Netrin-G1

1

3

High-throughput

0.536

High

178300

NPC1
NPC intracellular cholesterol transporter 1

1

0

High-throughput

0.513

High

249760

DOK2
Docking protein 2

1

0

High-throughput

0.513

High

354128

CLPT1
Putative lipid scramblase CLPTM1

1

0

High-throughput

0.513

High

535196

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.513

High

565636

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

0

High-throughput

0.513

High

719957

HMOX2
Heme oxygenase 2

1

0

High-throughput

0.513

High

873776

CD151
CD151 antigen

1

0

High-throughput

0.513

High

1006017

ASIC1
Acid-sensing ion channel 1

1

0

High-throughput

0.513

High

1089106

HYAL2
Hyaluronidase-2

1

0

High-throughput

0.513

High

1143622

NOMO1
BOS complex subunit NOMO1

1

0

High-throughput

0.513

High

1159150

SGCB
Beta-sarcoglycan

1

0

High-throughput

0.513

High

1244870

NFXL1
NF-X1-type zinc finger protein NFXL1

1

0

High-throughput

0.513

High

1244873

PGAP1
GPI inositol-deacylase

1

0

High-throughput

0.513

High

1244874

ERMP1
Endoplasmic reticulum metallopeptidase 1

1

0

High-throughput

0.513

High

1244876

AMGO1
Amphoterin-induced protein 1

1

0

High-throughput

0.513

High

1244886

CADM4
Cell adhesion molecule 4

1

0

High-throughput

0.513

High

1244891

PMGT1
Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1

1

0

High-throughput

0.513

High

1244892

EDEM1
ER degradation-enhancing alpha-mannosidase-like protein 1

1

0

High-throughput

0.513

High

1244896

SEC62
Translocation protein SEC62

1

0

High-throughput

0.513

High

1244897

TM9S2
Transmembrane 9 superfamily member 2

1

0

High-throughput

0.513

High

1244907

S38AA
Solute carrier family 38 member 10

1

0

High-throughput

0.513

High

1244910

CLN6
Ceroid-lipofuscinosis neuronal protein 6

1

0

High-throughput

0.513

High

1244912

SELN
Selenoprotein N

1

0

High-throughput

0.513

High

1244913

HCST
Hematopoietic cell signal transducer

1

0

High-throughput

0.513

High

1101357

SG2A2
Mammaglobin-A

1

2

High-throughput

0.489

High

1244884

SIA7C
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3

1

1

High-throughput

0.489

High

1244899

SPXN
Spexin

1

1

High-throughput

0.489

High

1244909

T106B
Transmembrane protein 106B

1

1

High-throughput

0.479

High

218338

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

418210

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.458

High

1244868

RICTR
Rapamycin-insensitive companion of mTOR

1

0

High-throughput

0.458

High

1244871

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.437

High

1244915

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.437

High

380074

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

0

High-throughput

0.426

High

1244890

CTL1
Choline transporter-like protein 1

1

0

High-throughput

0.426

High

1244903

ZDHC5
Palmitoyltransferase ZDHHC5

1

0

High-throughput

0.426

High

318993

MICA2
[F-actin]-monooxygenase MICAL2

1

1

High-throughput

0.407

High

1244904

TM38A
Trimeric intracellular cation channel type A

3

0

High-throughput

0.347

High

1244877

GLBL2
Beta-galactosidase-1-like protein 2

2

0

High-throughput

0.328

High

1244880

F177A
Protein FAM177A1

2

0

High-throughput

0.328

High

1244893

STAM1
Signal transducing adapter molecule 1

2

0

High-throughput

0.328

High

1244905

TM231
Transmembrane protein 231

2

0

High-throughput

0.328

High

1244914

MTFP1
Mitochondrial fission process protein 1

2

0

High-throughput

0.328

High

280928

HYPM
Huntingtin-interacting protein M

1

0

High-throughput

0.279

Low

1177810

CL12B
C-type lectin domain family 12 member B

1

0

High-throughput

0.279

Low

1244869

UQCC3
Ubiquinol-cytochrome-c reductase complex assembly factor 3

1

0

High-throughput

0.279

Low

1244885

DIK2A
Divergent protein kinase domain 2A

1

0

High-throughput

0.279

Low

1244898

S2533
Solute carrier family 25 member 33

1

0

High-throughput

0.279

Low

275043

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

0

High-throughput

0.249

Low

1004722

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.249

Low

1155470

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.249

Low

1244879

FA20C
Extracellular serine/threonine protein kinase FAM20C

1

0

High-throughput

0.249

Low

326575

MFN2
Mitofusin-2

1

0

High-throughput

0.232

Low

1244894

S2546
Mitochondrial outer membrane protein SLC25A46

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025