Protein: SYF2
Pre-mRNA-splicing factor SYF2 (PRP19 complex protein 31) (Synthetic lethal with CDC40 protein 2)

Gene: SYF2
Organism: Saccharomyces cerevisiae S288C
Interactions: 55
UniProt ID: P53277

Gene Ontology (top 5):
GO:0000398 - mRNA splicing, via spliceosome
GO:0000974 - Prp19 complex
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0071004 - U2-type prespliceosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

919217

CEF1
Pre-mRNA-splicing factor CEF1

6

0

Small-scale

0.897

High

919219

SYF1
Pre-mRNA-splicing factor SYF1

8

1

Small-scale

0.752

High

739173

PRP19
Pre-mRNA-processing factor 19

7

0

Small-scale

0.718

High

919230

CLF1
Pre-mRNA-splicing factor CLF1

5

1

Small-scale

0.717

High

919228

CWC2
Pre-mRNA-splicing factor CWC2

3

0

High-throughput

0.638

High

919221

SN309
Pre-mRNA-splicing factor SNT309

3

0

Small-scale

0.622

High

638070

ISY1
Pre-mRNA-splicing factor ISY1

2

0

Small-scale

0.595

High

664605

PRP22
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22

2

3

Small-scale

0.595

High

700126

PRP45
Pre-mRNA-processing protein 45

1

0

High-throughput

0.586

High

751763

PRP8
Pre-mRNA-splicing factor 8

1

0

High-throughput

0.586

High

781576

NTR2
Pre-mRNA-splicing factor NTR2

2

0

Small-scale

0.585

High

797679

NTC20
Pre-mRNA-splicing factor NTC20

2

0

Small-scale

0.585

High

919231

PRP46
Pre-mRNA-splicing factor PRP46

2

0

High-throughput

0.585

High

628216

PRP2
Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2

2

3

High-throughput

0.584

High

919225

PRP11
Pre-mRNA-splicing factor PRP11

2

0

High-throughput

0.576

High

702266

YJU2
Splicing factor YJU2

2

0

Small-scale

0.569

High

817132

RSMB
Small nuclear ribonucleoprotein-associated protein B

2

0

High-throughput

0.559

High

919216

CWC21
Pre-mRNA-splicing factor CWC21

2

0

Small-scale

0.559

High

919227

RU2A
U2 small nuclear ribonucleoprotein A'

2

0

High-throughput

0.559

High

919211

CWC25
Pre-mRNA-splicing factor CWC25

2

0

High-throughput

0.547

High

919223

SP382
Pre-mRNA-splicing factor SPP382

1

0

Small-scale

0.513

High

917436

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

3

High-throughput

0.489

High

441200

KAPA
cAMP-dependent protein kinase type 1

1

0

High-throughput

0.480

High

590209

PRP16
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16

1

3

High-throughput

0.479

High

744137

BRR2
Pre-mRNA-splicing helicase BRR2

1

1

High-throughput

0.479

High

625111

PRP9
Pre-mRNA-splicing factor PRP9

1

0

High-throughput

0.458

High

672063

BUD31
Pre-mRNA-splicing factor BUD31

1

0

High-throughput

0.458

High

679909

CDC48
Cell division control protein 48

1

0

High-throughput

0.458

High

739256

PRP21
Pre-mRNA-splicing factor PRP21

1

0

High-throughput

0.458

High

757508

NCBP1
Nuclear cap-binding protein complex subunit 1

1

0

High-throughput

0.458

High

780198

SN114
Pre-mRNA-splicing factor SNU114

1

0

High-throughput

0.458

High

796450

SLT11
Pre-mRNA-splicing factor SLT11

1

0

High-throughput

0.458

High

808867

UME6
Transcriptional regulatory protein UME6

1

0

High-throughput

0.458

High

820823

RUXG
Small nuclear ribonucleoprotein G

1

0

High-throughput

0.458

High

826692

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

829945

PRP17
Pre-mRNA-processing factor 17

1

0

High-throughput

0.458

High

847811

SMD3
Small nuclear ribonucleoprotein Sm D3

1

0

High-throughput

0.458

High

863088

CWC26
Pre-mRNA-splicing factor CWC26

1

0

High-throughput

0.458

High

892766

SF3B1
U2 snRNP component HSH155

1

0

High-throughput

0.458

High

919210

CWC22
Pre-mRNA-splicing factor CWC22

1

0

High-throughput

0.458

High

919212

RUXF
Small nuclear ribonucleoprotein F

1

0

High-throughput

0.458

High

919213

SMD1
Small nuclear ribonucleoprotein Sm D1

1

0

High-throughput

0.458

High

919214

CUS1
Cold sensitive U2 snRNA suppressor 1

1

0

High-throughput

0.458

High

919215

SLU7
Pre-mRNA-splicing factor SLU7

1

0

High-throughput

0.458

High

919218

CWC15
Pre-mRNA-splicing factor CWC15

1

0

High-throughput

0.458

High

919220

RSE1
Pre-mRNA-splicing factor RSE1

1

0

High-throughput

0.458

High

919222

SMD2
Small nuclear ribonucleoprotein Sm D2

1

0

High-throughput

0.458

High

919224

RDS3
Pre-mRNA-splicing factor RDS3

1

0

High-throughput

0.458

High

919226

NCBP2
Nuclear cap-binding protein subunit 2

1

0

High-throughput

0.458

High

524665

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

527270

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

742057

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

545699

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.426

High

919229

PIN2
[PSI+] induction protein 2

1

0

High-throughput

0.282

High

597521

EF3A
Elongation factor 3A

1

0

High-throughput

0.269

Low


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Last updated: 11Aug2025