Protein: CWC22
Pre-mRNA-splicing factor CWC22 (Complexed with CEF1 protein 22)

Gene: CWC22
Organism: Saccharomyces cerevisiae S288C
Interactions: 65
UniProt ID: P53333

Gene Ontology (top 5):
GO:0000398 - mRNA splicing, via spliceosome
GO:0000974 - Prp19 complex
GO:0003723 - RNA binding
GO:0005684 - U2-type spliceosomal complex
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

751764

PRP8
Pre-mRNA-splicing factor 8

3

1

High-throughput

0.855

High

744138

BRR2
Pre-mRNA-splicing helicase BRR2

2

3

High-throughput

0.789

High

664606

PRP22
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22

2

3

Small-scale

0.768

High

628217

PRP2
Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2

2

3

High-throughput

0.754

High

919728

CEF1
Pre-mRNA-splicing factor CEF1

6

2

Small-scale

0.733

High

739174

PRP19
Pre-mRNA-processing factor 19

4

4

High-throughput

0.687

High

919738

CWC2
Pre-mRNA-splicing factor CWC2

3

1

High-throughput

0.667

High

919740

CLF1
Pre-mRNA-splicing factor CLF1

3

3

High-throughput

0.662

High

700127

PRP45
Pre-mRNA-processing protein 45

3

0

High-throughput

0.634

High

780199

SN114
Pre-mRNA-splicing factor SNU114

3

0

High-throughput

0.634

High

590211

PRP16
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16

1

3

High-throughput

0.618

High

702267

YJU2
Splicing factor YJU2

3

0

High-throughput

0.616

High

892767

SF3B1
U2 snRNP component HSH155

2

1

High-throughput

0.611

High

919730

SYF1
Pre-mRNA-splicing factor SYF1

2

2

High-throughput

0.611

High

919741

PRP46
Pre-mRNA-splicing factor PRP46

2

2

High-throughput

0.611

High

545726

SSB1
Ribosome-associated molecular chaperone SSB1

2

3

High-throughput

0.601

High

863089

CWC26
Pre-mRNA-splicing factor CWC26

1

0

High-throughput

0.586

High

524688

HSP71
Heat shock protein SSA1

2

2

High-throughput

0.571

High

579808

HSC82
ATP-dependent molecular chaperone HSC82

2

2

High-throughput

0.571

High

817134

RSMB
Small nuclear ribonucleoprotein-associated protein B

2

0

High-throughput

0.559

High

919732

SN309
Pre-mRNA-splicing factor SNT309

2

0

High-throughput

0.559

High

919737

RU2A
U2 small nuclear ribonucleoprotein A'

2

0

High-throughput

0.559

High

919721

CWC25
Pre-mRNA-splicing factor CWC25

2

0

High-throughput

0.547

High

416463

HXKA
Hexokinase-1

1

1

High-throughput

0.500

High

438463

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

0

High-throughput

0.493

High

450621

FAS1
Fatty acid synthase subunit beta

1

0

High-throughput

0.479

High

796451

SLT11
Pre-mRNA-splicing factor SLT11

1

1

High-throughput

0.479

High

826539

MSL1
U2 small nuclear ribonucleoprotein B''

1

3

High-throughput

0.479

High

829946

PRP17
Pre-mRNA-processing factor 17

1

3

High-throughput

0.479

High

919736

NCBP2
Nuclear cap-binding protein subunit 2

1

1

High-throughput

0.479

High

919739

RIO1
Serine/threonine-protein kinase RIO1

1

1

High-throughput

0.479

High

816697

VAB2
Biogenesis of lysosome-related organelles complex 1 subunit VAB2

1

0

High-throughput

0.460

High

625113

PRP9
Pre-mRNA-splicing factor PRP9

1

0

High-throughput

0.458

High

638071

ISY1
Pre-mRNA-splicing factor ISY1

1

0

High-throughput

0.458

High

672064

BUD31
Pre-mRNA-splicing factor BUD31

1

0

High-throughput

0.458

High

739257

PRP21
Pre-mRNA-splicing factor PRP21

1

0

High-throughput

0.458

High

757509

NCBP1
Nuclear cap-binding protein complex subunit 1

1

0

High-throughput

0.458

High

797680

NTC20
Pre-mRNA-splicing factor NTC20

1

0

High-throughput

0.458

High

847812

SMD3
Small nuclear ribonucleoprotein Sm D3

1

0

High-throughput

0.458

High

919210

SYF2
Pre-mRNA-splicing factor SYF2

1

0

High-throughput

0.458

High

919723

RUXF
Small nuclear ribonucleoprotein F

1

0

High-throughput

0.458

High

919724

SMD1
Small nuclear ribonucleoprotein Sm D1

1

0

High-throughput

0.458

High

919725

SPP2
Pre-mRNA-splicing factor SPP2

1

0

High-throughput

0.458

High

919726

SLU7
Pre-mRNA-splicing factor SLU7

1

0

High-throughput

0.458

High

919727

CWC21
Pre-mRNA-splicing factor CWC21

1

0

High-throughput

0.458

High

919729

CWC15
Pre-mRNA-splicing factor CWC15

1

0

High-throughput

0.458

High

919731

RSE1
Pre-mRNA-splicing factor RSE1

1

0

High-throughput

0.458

High

919733

SMD2
Small nuclear ribonucleoprotein Sm D2

1

0

High-throughput

0.458

High

919734

RDS3
Pre-mRNA-splicing factor RDS3

1

0

High-throughput

0.458

High

919735

PRP11
Pre-mRNA-splicing factor PRP11

1

0

High-throughput

0.458

High

607775

HXKG
Glucokinase-1

1

1

High-throughput

0.457

High

393098

HSP82
ATP-dependent molecular chaperone HSP82

1

2

High-throughput

0.445

High

527291

HSP72
Heat shock protein SSA2

1

2

High-throughput

0.445

High

727209

HS104
Heat shock protein 104

1

1

High-throughput

0.445

High

742072

HSP7F
Heat shock protein homolog SSE1

1

5

High-throughput

0.445

High

742909

HSP79
Heat shock protein homolog SSE2

1

5

High-throughput

0.445

High

752560

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.445

High

819372

SSB2
Ribosome-associated molecular chaperone SSB2

1

3

High-throughput

0.445

High

707762

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

816332

HSP7E
Heat shock protein SSC3, mitochondrial

1

0

High-throughput

0.426

High

919722

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.426

High

740118

SCM4
Protein SCM4

1

0

High-throughput

0.265

Low

554948

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

0

High-throughput

0.261

Low

811126

TCPZ
T-complex protein 1 subunit zeta

1

0

High-throughput

0.232

Low

811360

CAJ1
Protein CAJ1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025