Protein: TRIPC
E3 ubiquitin-protein ligase TRIP12 (EC 2.3.2.26) (E3 ubiquitin-protein ligase for Arf) (ULF) (HECT-type E3 ubiquitin transferase TRIP12) (Thyroid receptor-interacting protein 12) (TR-interacting protein 12) (TRIP-12)

Gene: TRIPC, TRIP12
Organism: Homo sapiens
Interactions: 204
UniProt ID: Q14669

Gene Ontology (top 5):
GO:0000209 - protein polyubiquitination
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0006281 - DNA repair

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

849331

UB2D1
Ubiquitin-conjugating enzyme E2 D1

5

20

Small-scale

0.924

High

932515

UB2L3
Ubiquitin-conjugating enzyme E2 L3

4

20

Small-scale

0.888

High

475762

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

3

20

Small-scale

0.834

High

790781

CDN2A
Cyclin-dependent kinase inhibitor 2A

5

14

Small-scale

0.720

High

346787

MYC
Myc proto-oncogene protein

4

14

Small-scale

0.709

High

1056607

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

5

17

Small-scale

0.709

High

1056647

UB2D4
Ubiquitin-conjugating enzyme E2 D4

1

20

High-throughput

0.691

High

274092

XRP2
Protein XRP2

3

1

High-throughput

0.667

High

871856

BCAT1
Branched-chain-amino-acid aminotransferase, cytosolic

3

1

High-throughput

0.667

High

1032091

EIF3I
Eukaryotic translation initiation factor 3 subunit I

3

19

High-throughput

0.667

High

919729

UB2D2
Ubiquitin-conjugating enzyme E2 D2

1

20

High-throughput

0.647

High

455441

PARP1
Poly [ADP-ribose] polymerase 1

2

16

Small-scale

0.634

High

1056609

FBXW7
F-box/WD repeat-containing protein 7

2

12

Small-scale

0.634

High

427891

CAN1
Calpain-1 catalytic subunit

2

11

High-throughput

0.628

High

848032

MECP2
Methyl-CpG-binding protein 2

2

5

High-throughput

0.628

High

1056604

KBTB7
Kelch repeat and BTB domain-containing protein 7

2

2

High-throughput

0.628

High

244437

BRD4
Bromodomain-containing protein 4

2

14

Small-scale

0.624

High

159059

UB2L6
Ubiquitin/ISG15-conjugating enzyme E2 L6

1

20

High-throughput

0.618

High

227458

PRKN
E3 ubiquitin-protein ligase parkin

1

20

High-throughput

0.618

High

1056641

HECD1
E3 ubiquitin-protein ligase HECTD1

1

16

High-throughput

0.618

High

927043

1433Z
14-3-3 protein zeta/delta

2

20

High-throughput

0.611

High

1056572

IF16
Gamma-interferon-inducible protein 16

2

4

High-throughput

0.611

High

850046

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

2

15

High-throughput

0.601

High

1043794

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

2

15

High-throughput

0.594

High

552727

RFA2
Replication protein A 32 kDa subunit

2

7

High-throughput

0.584

High

651206

RFA1
Replication protein A 70 kDa DNA-binding subunit

2

10

High-throughput

0.584

High

720467

RFA3
Replication protein A 14 kDa subunit

2

8

High-throughput

0.584

High

917266

H4
Histone H4

2

6

High-throughput

0.584

High

918363

H2B1C
Histone H2B type 1-C/E/F/G/I

2

16

High-throughput

0.584

High

934762

H31
Histone H3.1

2

8

High-throughput

0.584

High

1056639

ZRAN1
Ubiquitin thioesterase ZRANB1

2

16

High-throughput

0.584

High

1056597

ARF
Tumor suppressor ARF

1

2

Small-scale

0.578

High

1056566

OPCM
Opioid-binding protein/cell adhesion molecule

2

3

High-throughput

0.574

High

727867

SOX6
Transcription factor SOX-6

1

14

Small-scale

0.573

High

1056586

PTF1A
Pancreas transcription factor 1 subunit alpha

1

2

Small-scale

0.573

High

375743

GBA1
Lysosomal acid glucosylceramidase

1

2

Small-scale

0.561

High

1039422

ULA1
NEDD8-activating enzyme E1 regulatory subunit

1

7

Small-scale

0.561

High

819629

NRIP1
Nuclear receptor-interacting protein 1

1

4

High-throughput

0.541

High

1056617

LCOR
Ligand-dependent corepressor

1

2

High-throughput

0.541

High

1021600

TAF10
Transcription initiation factor TFIID subunit 10

1

0

Small-scale

0.537

High

1030662

NMI
N-myc-interactor

1

0

Small-scale

0.537

High

71119

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

18

High-throughput

0.536

High

149860

RFXK
DNA-binding protein RFXANK

1

13

High-throughput

0.536

High

168635

IMA6
Importin subunit alpha-6

1

13

High-throughput

0.536

High

238678

IMA7
Importin subunit alpha-7

1

13

High-throughput

0.536

High

269733

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

1

20

High-throughput

0.536

High

369606

ESR1
Estrogen receptor

1

20

High-throughput

0.536

High

529121

CFTR
Cystic fibrosis transmembrane conductance regulator

1

7

High-throughput

0.536

High

537542

AK1A1
Aldo-keto reductase family 1 member A1

1

1

High-throughput

0.536

High

736465

RL4
Large ribosomal subunit protein uL4

1

5

High-throughput

0.536

High

771967

VHL
von Hippel-Lindau disease tumor suppressor

1

2

High-throughput

0.536

High

853599

IMA5
Importin subunit alpha-5

1

13

High-throughput

0.536

High

913529

RL7A
Large ribosomal subunit protein eL8

1

15

High-throughput

0.536

High

922059

RL39
Large ribosomal subunit protein eL39

1

1

High-throughput

0.536

High

923013

RL11
Large ribosomal subunit protein uL5

1

3

High-throughput

0.536

High

948788

HMGN5
High mobility group nucleosome-binding domain-containing protein 5

1

1

High-throughput

0.536

High

971171

H11
Histone H1.1

1

7

High-throughput

0.536

High

986676

EXOS9
Exosome complex component RRP45

1

8

High-throughput

0.536

High

992771

SRSF1
Serine/arginine-rich splicing factor 1

1

20

High-throughput

0.536

High

1019742

ILF3
Interleukin enhancer-binding factor 3

1

16

High-throughput

0.536

High

1039559

SNW1
SNW domain-containing protein 1

1

2

High-throughput

0.536

High

1040555

KRR1
KRR1 small subunit processome component homolog

1

3

High-throughput

0.536

High

1056565

NUMA1
Nuclear mitotic apparatus protein 1

1

11

High-throughput

0.536

High

1056569

TEAD2
Transcriptional enhancer factor TEF-4

1

3

High-throughput

0.536

High

1056573

H2B2E
Histone H2B type 2-E

1

16

High-throughput

0.536

High

1056594

RN168
E3 ubiquitin-protein ligase RNF168

1

2

Small-scale

0.536

High

1056600

UBP32
Ubiquitin carboxyl-terminal hydrolase 32

1

19

High-throughput

0.536

High

1056611

EFMT3
EEF1A lysine methyltransferase 3

1

8

High-throughput

0.536

High

1056621

NPAS1
Neuronal PAS domain-containing protein 1

1

10

High-throughput

0.536

High

1056622

H2AJ
Histone H2A.J

1

10

High-throughput

0.536

High

1056625

UBXN6
UBX domain-containing protein 6

1

2

High-throughput

0.536

High

1056627

TOLIP
Toll-interacting protein

1

3

High-throughput

0.536

High

1056629

SENP3
Sentrin-specific protease 3

1

8

High-throughput

0.536

High

1056640

CYH4
Cytohesin-4

1

2

High-throughput

0.536

High

1056642

TPX2
Targeting protein for Xklp2

1

5

High-throughput

0.536

High

1056643

ABT1
Activator of basal transcription 1

1

1

High-throughput

0.536

High

1056645

PHF8
Histone lysine demethylase PHF8

1

12

High-throughput

0.536

High

973071

RL6
Large ribosomal subunit protein eL6

1

5

High-throughput

0.515

High

278612

DCTN3
Dynactin subunit 3

1

0

High-throughput

0.513

High

597509

GSTM3
Glutathione S-transferase Mu 3

1

0

High-throughput

0.513

High

1056578

PLBL1
Phospholipase B-like 1

1

0

High-throughput

0.513

High

1056592

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

1056606

GGH
Gamma-glutamyl hydrolase

1

0

High-throughput

0.513

High

171396

SMAD9
Mothers against decapentaplegic homolog 9

1

20

High-throughput

0.508

High

302395

CSTN1
Calsyntenin-1

1

5

Small-scale

0.508

High

174890

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

17

High-throughput

0.501

High

305175

UBE4B
Ubiquitin conjugation factor E4 B

1

2

Small-scale

0.501

High

507422

ERG
Transcriptional regulator ERG

1

5

Small-scale

0.501

High

942659

SRPK2
SRSF protein kinase 2

1

20

High-throughput

0.501

High

1041322

CUL2
Cullin-2

1

15

Small-scale

0.501

High

418274

NPM
Nucleophosmin

1

7

Small-scale

0.500

High

328215

LGI1
Leucine-rich glioma-inactivated protein 1

1

1

High-throughput

0.489

High

615405

KALM
Anosmin-1

1

2

High-throughput

0.489

High

948435

RT06
Small ribosomal subunit protein bS6m

1

1

High-throughput

0.489

High

1056602

OR6T1
Olfactory receptor 6T1

1

3

High-throughput

0.489

High

1056605

JPH3
Junctophilin-3

1

6

High-throughput

0.489

High

1056613

CERS2
Ceramide synthase 2

1

2

High-throughput

0.489

High

1056619

CC85A
Coiled-coil domain-containing protein 85A

1

2

High-throughput

0.489

High

1056620

TCPQM
T-complex protein 1 subunit theta-like 2

1

20

High-throughput

0.489

High

1056626

DNAI2
Dynein axonemal intermediate chain 2

1

8

High-throughput

0.489

High

1056646

PSG11
Pregnancy-specific beta-1-glycoprotein 11

1

4

High-throughput

0.489

High

61521

CRNS1
Carnosine synthase 1

1

0

Small-scale

0.486

High

122754

MEN1
Menin

1

1

High-throughput

0.479

High

148817

CTRO
Citron Rho-interacting kinase

1

17

High-throughput

0.479

High

179635

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

7

High-throughput

0.479

High

233450

NUPR1
Nuclear protein 1

1

2

High-throughput

0.479

High

255778

OBSL1
Obscurin-like protein 1

1

6

High-throughput

0.479

High

268088

EED
Polycomb protein EED

1

20

High-throughput

0.479

High

322628

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

20

High-throughput

0.479

High

350173

RASK
GTPase KRas

1

7

High-throughput

0.479

High

374235

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

20

High-throughput

0.479

High

391698

H2A1B
Histone H2A type 1-B/E

1

10

High-throughput

0.479

High

523751

XRCC6
X-ray repair cross-complementing protein 6

1

10

High-throughput

0.479

High

632730

TYY1
Transcriptional repressor protein YY1

1

12

Small-scale

0.479

High

643505

PTBP1
Polypyrimidine tract-binding protein 1

1

12

Small-scale

0.479

High

646888

1433T
14-3-3 protein theta

1

20

High-throughput

0.479

High

652853

APEX1
DNA repair nuclease/redox regulator APEX1

1

2

High-throughput

0.479

High

683347

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.479

High

684036

1433S
14-3-3 protein sigma

1

20

High-throughput

0.479

High

707630

H2B1B
Histone H2B type 1-B

1

16

High-throughput

0.479

High

742295

SYUA
Alpha-synuclein

1

5

High-throughput

0.479

High

760062

RL3
Large ribosomal subunit protein uL3

1

6

High-throughput

0.479

High

779411

CCNF
Cyclin-F

1

13

High-throughput

0.479

High

805419

MP2K3
Dual specificity mitogen-activated protein kinase kinase 3

1

18

High-throughput

0.479

High

818046

SOX2
Transcription factor SOX-2

1

15

High-throughput

0.479

High

824006

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

10

High-throughput

0.479

High

828226

CENPA
Histone H3-like centromeric protein A

1

8

High-throughput

0.479

High

835757

GSK3B
Glycogen synthase kinase-3 beta

1

9

Small-scale

0.479

High

841723

CDK9
Cyclin-dependent kinase 9

1

15

High-throughput

0.479

High

857467

HMGA2
High mobility group protein HMGI-C

1

1

Small-scale

0.479

High

874933

TERA
Transitional endoplasmic reticulum ATPase

1

10

High-throughput

0.479

High

902584

SUMO2
Small ubiquitin-related modifier 2

1

5

High-throughput

0.479

High

904561

1433G
14-3-3 protein gamma

1

20

High-throughput

0.479

High

909564

1433E
14-3-3 protein epsilon

1

14

High-throughput

0.479

High

952337

H33
Histone H3.3

1

8

High-throughput

0.479

High

982011

1433F
14-3-3 protein eta

1

20

High-throughput

0.479

High

1014120

CPSF1
Cleavage and polyadenylation specificity factor subunit 1

1

8

High-throughput

0.479

High

1026997

CBX3
Chromobox protein homolog 3

1

20

High-throughput

0.479

High

1029426

TIF1B
Transcription intermediary factor 1-beta

1

17

High-throughput

0.479

High

1056563

MDC1
Mediator of DNA damage checkpoint protein 1

1

15

Small-scale

0.479

High

1056564

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

11

High-throughput

0.479

High

1056567

SUZ12
Polycomb protein SUZ12

1

1

High-throughput

0.479

High

1056568

BRD3
Bromodomain-containing protein 3

1

19

High-throughput

0.479

High

1056570

TRADD
Tumor necrosis factor receptor type 1-associated DEATH domain protein

1

1

Small-scale

0.479

High

1056571

EZH2
Histone-lysine N-methyltransferase EZH2

1

9

High-throughput

0.479

High

1056576

RN123
E3 ubiquitin-protein ligase RNF123

1

20

High-throughput

0.479

High

1056577

A16L1
Autophagy-related protein 16-1

1

12

High-throughput

0.479

High

1056584

MOB3C
MOB kinase activator 3C

1

4

High-throughput

0.479

High

1056585

MEPCE
7SK snRNA methylphosphate capping enzyme

1

2

High-throughput

0.479

High

1056587

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

7

High-throughput

0.479

High

1056590

SERC5
Serine incorporator 5

1

2

Small-scale

0.479

High

1056591

TAXB1
Tax1-binding protein 1

1

19

High-throughput

0.479

High

1056593

SMC5
Structural maintenance of chromosomes protein 5

1

7

High-throughput

0.479

High

1056596

SIR6
NAD-dependent protein deacylase sirtuin-6

1

13

High-throughput

0.479

High

1056599

FBX22
F-box only protein 22

1

1

High-throughput

0.479

High

1056601

NUP43
Nucleoporin Nup43

1

20

High-throughput

0.479

High

1056603

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

1

High-throughput

0.479

High

1056608

SMCE1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

1

14

Small-scale

0.479

High

1056610

FBX32
F-box only protein 32

1

1

High-throughput

0.479

High

1056623

GNL3
Guanine nucleotide-binding protein-like 3

1

8

Small-scale

0.479

High

1056624

RBM4
RNA-binding protein 4

1

15

Small-scale

0.479

High

1056628

CCDC8
Coiled-coil domain-containing protein 8

1

5

High-throughput

0.479

High

1056631

ECT2
Protein ECT2

1

12

Small-scale

0.479

High

1056632

WDR76
WD repeat-containing protein 76

1

20

High-throughput

0.479

High

1056633

ANLN
Anillin

1

2

High-throughput

0.479

High

1056634

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

13

High-throughput

0.479

High

1056636

PIHD1
PIH1 domain-containing protein 1

1

3

Small-scale

0.479

High

1056637

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

2

High-throughput

0.479

High

815875

MTR1A
Melatonin receptor type 1A

1

6

High-throughput

0.464

High

825699

MTR1B
Melatonin receptor type 1B

1

6

High-throughput

0.464

High

1056588

SLN11
Schlafen family member 11

1

0

High-throughput

0.458

High

1056589

SHLD2
Shieldin complex subunit 2

1

0

High-throughput

0.458

High

1056595

STAG2
Cohesin subunit SA-2

1

0

High-throughput

0.458

High

1056612

DCPS
m7GpppX diphosphatase

1

0

High-throughput

0.458

High

1056618

CEP19
Centrosomal protein of 19 kDa

1

0

High-throughput

0.458

High

1056648

ZN330
Zinc finger protein 330

1

0

High-throughput

0.458

High

1056581

MCAF1
Activating transcription factor 7-interacting protein 1

1

10

High-throughput

0.457

High

1056635

DISC1
Disrupted in schizophrenia 1 protein

1

5

High-throughput

0.457

High

47415

RPSA2
Small ribosomal subunit protein uS2B

1

9

High-throughput

0.445

High

217883

PRKY
Putative serine/threonine-protein kinase PRKY

1

20

High-throughput

0.445

High

402006

JUN
Transcription factor Jun

1

10

High-throughput

0.445

High

1056644

AKP8L
A-kinase anchor protein 8-like

1

9

High-throughput

0.445

High

1056616

SPTCS
Spatacsin

1

0

Small-scale

0.438

High

393201

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

4

High-throughput

0.437

High

830742

ARL4D
ADP-ribosylation factor-like protein 4D

1

8

High-throughput

0.437

High

1002032

ARL16
ADP-ribosylation factor-like protein 16

1

8

High-throughput

0.437

High

1053556

GRM2
Metabotropic glutamate receptor 2

1

3

High-throughput

0.437

High

1056579

LMBRL
Protein LMBR1L

1

4

High-throughput

0.437

High

1056580

LRC31
Leucine-rich repeat-containing protein 31

1

3

High-throughput

0.437

High

1056582

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.437

High

1056583

UBP53
Inactive ubiquitin carboxyl-terminal hydrolase 53

1

11

Small-scale

0.437

High

1056630

PKHA4
Pleckstrin homology domain-containing family A member 4

1

12

High-throughput

0.437

High

886283

DSCR9
Down syndrome critical region protein 9

1

2

High-throughput

0.417

High

484449

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

1

5

High-throughput

0.407

High

1056598

MOT11
Monocarboxylate transporter 11

1

2

High-throughput

0.407

High

150062

TYB4Y
Thymosin beta-4, Y-chromosomal

1

0

High-throughput

0.279

Low

1054803

FGFP1
Fibroblast growth factor-binding protein 1

1

0

High-throughput

0.279

Low

1056615

TET5A
Terminal nucleotidyltransferase 5A

1

0

High-throughput

0.279

Low

1056649

SPCS1
Signal peptidase complex subunit 1

1

0

High-throughput

0.279

Low

1056650

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

0

High-throughput

0.279

Low

1056575

OCAD2
OCIA domain-containing protein 2

1

0

High-throughput

0.269

Low

1056574

MIC60
MICOS complex subunit MIC60

1

0

High-throughput

0.249

Low

1056614

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.249

Low

1056638

CELR3
Cadherin EGF LAG seven-pass G-type receptor 3

1

0

Small-scale

0.238

Low


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Last updated: 15 Jul 2024