Protein: NUMBL
Numb-like protein (Numb-related protein) (Numb-R)

Gene: NUMBL
Organism: Homo sapiens
Interactions: 107
UniProt ID: Q9Y6R0

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0007399 - nervous system development
GO:0007409 - axonogenesis
GO:0019221 - cytokine-mediated signaling pathway
GO:0019538 - protein metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

683860

1433B
14-3-3 protein beta/alpha

4

20

High-throughput

0.699

High

905324

1433G
14-3-3 protein gamma

4

20

High-throughput

0.699

High

982672

1433F
14-3-3 protein eta

4

20

High-throughput

0.699

High

1377882

TRAF6
TNF receptor-associated factor 6

4

12

Small-scale

0.692

High

833676

NUMB
Protein numb homolog

1

4

High-throughput

0.691

High

1348541

TAB2
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2

2

4

Small-scale

0.642

High

910216

1433E
14-3-3 protein epsilon

2

3

High-throughput

0.635

High

792872

EAA3
Excitatory amino acid transporter 3

2

1

High-throughput

0.628

High

1217293

UN5CL
UNC5C-like protein

2

1

High-throughput

0.628

High

151276

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

16

High-throughput

0.618

High

1252574

LNX1
E3 ubiquitin-protein ligase LNX

1

18

Small-scale

0.618

High

927720

1433Z
14-3-3 protein zeta/delta

2

20

High-throughput

0.611

High

1162018

SPSB3
SPRY domain-containing SOCS box protein 3

3

9

High-throughput

0.597

High

339214

EGFR
Epidermal growth factor receptor

2

20

High-throughput

0.595

High

129608

TRAF5
TNF receptor-associated factor 5

2

10

Small-scale

0.586

High

350748

RASK
GTPase KRas

2

19

High-throughput

0.584

High

547305

EZRI
Ezrin

2

6

High-throughput

0.584

High

1347168

RFOX1
RNA binding protein fox-1 homolog 1

1

2

High-throughput

0.582

High

1262102

KBTB7
Kelch repeat and BTB domain-containing protein 7

2

5

High-throughput

0.574

High

370840

ESR1
Estrogen receptor

2

11

High-throughput

0.571

High

1377729

GRIP1
Glutamate receptor-interacting protein 1

1

17

Small-scale

0.555

High

647430

1433T
14-3-3 protein theta

1

20

High-throughput

0.554

High

868835

ATX1
Ataxin-1

1

1

High-throughput

0.541

High

1333676

PAAT
ATPase PAAT

1

3

High-throughput

0.536

High

349044

RASN
GTPase NRas

2

19

High-throughput

0.533

High

914507

RB11A
Ras-related protein Rab-11A

2

4

High-throughput

0.533

High

655522

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

6

High-throughput

0.515

High

960354

CDK5
Cyclin-dependent kinase 5

1

4

High-throughput

0.515

High

1348774

GTSE1
G2 and S phase-expressed protein 1

1

3

High-throughput

0.489

High

1355295

LIMA1
LIM domain and actin-binding protein 1

1

4

High-throughput

0.489

High

146562

BHE40
Class E basic helix-loop-helix protein 40

1

1

High-throughput

0.481

High

1216743

SIAH1
E3 ubiquitin-protein ligase SIAH1

1

6

High-throughput

0.481

High

163540

XPO1
Exportin-1

1

4

High-throughput

0.479

High

279780

FLOT1
Flotillin-1

1

4

High-throughput

0.479

High

349776

RASH
GTPase HRas

1

14

High-throughput

0.479

High

430406

PROF1
Profilin-1

1

3

High-throughput

0.479

High

434112

LYN
Tyrosine-protein kinase Lyn

1

17

High-throughput

0.479

High

435814

IGF1R
Insulin-like growth factor 1 receptor

1

20

High-throughput

0.479

High

522301

CADH1
Cadherin-1

1

4

High-throughput

0.479

High

567359

CXA1
Gap junction alpha-1 protein

1

6

High-throughput

0.479

High

669117

PML
Protein PML

1

2

High-throughput

0.479

High

670311

MARCS
Myristoylated alanine-rich C-kinase substrate

1

5

High-throughput

0.479

High

882677

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

20

High-throughput

0.479

High

892147

ACTB
Actin, cytoplasmic 1

1

3

High-throughput

0.479

High

913225

ARF6
ADP-ribosylation factor 6

1

2

High-throughput

0.479

High

940618

CXAR
Coxsackievirus and adenovirus receptor

1

3

High-throughput

0.479

High

968355

ROR1
Inactive tyrosine-protein kinase transmembrane receptor ROR1

1

20

High-throughput

0.479

High

975142

CAV1
Caveolin-1

1

2

High-throughput

0.479

High

1259821

SMAP2
Stromal membrane-associated protein 2

1

8

High-throughput

0.479

High

1355059

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.479

High

1378219

NEMO
NF-kappa-B essential modulator

1

7

Small-scale

0.479

High

302458

CSTN1
Calsyntenin-1

1

4

High-throughput

0.470

High

521647

ACTN1
Alpha-actinin-1

1

0

High-throughput

0.460

High

638058

PSA3
Proteasome subunit alpha type-3

1

0

High-throughput

0.460

High

1294197

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

983286

UBE3A
Ubiquitin-protein ligase E3A

1

3

Small-scale

0.457

High

1038350

RIPK1
Receptor-interacting serine/threonine-protein kinase 1

1

11

High-throughput

0.439

High

1332489

ESRP2
Epithelial splicing regulatory protein 2

1

1

High-throughput

0.439

High

1356466

GPTC8
G patch domain-containing protein 8

1

1

High-throughput

0.439

High

1378124

MAGD1
Melanoma-associated antigen D1

1

3

High-throughput

0.439

High

171260

CTDSL
CTD small phosphatase-like protein

1

1

High-throughput

0.437

High

178900

STX7
Syntaxin-7

1

5

High-throughput

0.437

High

206249

TGON2
Trans-Golgi network integral membrane protein 2

1

5

High-throughput

0.437

High

213089

STX6
Syntaxin-6

1

5

High-throughput

0.437

High

262639

TULP3
Tubby-related protein 3

1

2

High-throughput

0.437

High

305705

ZFPL1
Zinc finger protein-like 1

1

1

High-throughput

0.437

High

318268

DIRA3
GTP-binding protein Di-Ras3

1

5

High-throughput

0.437

High

385821

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.437

High

411911

LCK
Tyrosine-protein kinase Lck

1

16

High-throughput

0.437

High

434325

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

20

High-throughput

0.437

High

451630

CLCA
Clathrin light chain A

1

9

High-throughput

0.437

High

451763

CLCB
Clathrin light chain B

1

9

High-throughput

0.437

High

508300

FGFR1
Fibroblast growth factor receptor 1

1

20

High-throughput

0.437

High

527924

LAMP2
Lysosome-associated membrane glycoprotein 2

1

5

High-throughput

0.437

High

564765

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.437

High

577081

PTPRA
Receptor-type tyrosine-protein phosphatase alpha

1

4

High-throughput

0.437

High

592093

RAB4A
Ras-related protein Rab-4A

1

5

High-throughput

0.437

High

608214

FGFR4
Fibroblast growth factor receptor 4

1

20

High-throughput

0.437

High

793552

MUC18
Cell surface glycoprotein MUC18

1

5

High-throughput

0.437

High

840620

VASP
Vasodilator-stimulated phosphoprotein

1

6

High-throughput

0.437

High

845841

RAB9A
Ras-related protein Rab-9A

1

8

High-throughput

0.437

High

884626

RAB25
Ras-related protein Rab-25

1

4

High-throughput

0.437

High

926067

AP2B1
AP-2 complex subunit beta

1

20

High-throughput

0.437

High

968531

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

1

20

High-throughput

0.437

High

1070492

RAB35
Ras-related protein Rab-35

1

6

High-throughput

0.437

High

1072640

EPHA7
Ephrin type-A receptor 7

1

14

High-throughput

0.437

High

1084268

OCLN
Occludin

1

3

High-throughput

0.437

High

1152241

LTOR1
Ragulator complex protein LAMTOR1

1

4

High-throughput

0.437

High

1200795

NAA40
N-alpha-acetyltransferase 40

1

3

High-throughput

0.437

High

1230453

CXD3
Gap junction delta-3 protein

1

6

High-throughput

0.437

High

1239788

NHLC2
NHL repeat-containing protein 2

1

2

High-throughput

0.437

High

1266623

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

3

High-throughput

0.437

High

1283124

CK052
Uncharacterized protein C11orf52

1

3

High-throughput

0.437

High

1316858

ACE2
Angiotensin-converting enzyme 2

1

2

High-throughput

0.437

High

1330466

DNJC5
DnaJ homolog subfamily C member 5

1

3

High-throughput

0.437

High

1331020

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.437

High

1335432

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.437

High

1347009

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

6

High-throughput

0.437

High

1357282

ALK
ALK tyrosine kinase receptor

1

18

High-throughput

0.437

High

1357953

LAMP3
Lysosome-associated membrane glycoprotein 3

1

5

High-throughput

0.437

High

1140480

BTBD8
BTB/POZ domain-containing protein 8

1

8

High-throughput

0.407

High

487072

LYAG
Lysosomal alpha-glucosidase

1

0

High-throughput

0.251

Low

770724

TPO
Thrombopoietin

1

0

High-throughput

0.251

Low

1166823

TMC5
Transmembrane channel-like protein 5

1

0

High-throughput

0.251

Low

262140

PEX14
Peroxisomal membrane protein PEX14

1

0

High-throughput

0.249

Low

1300457

RAB3I
Rab-3A-interacting protein

1

0

High-throughput

0.249

Low

1377715

CBY1
Protein chibby homolog 1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024