Protein: DXO
Decapping nuclease RAI1 (ScRai1) (EC 3.6.1.-) (NAD-capped RNA hydrolase RAI1) (DeNADding enzyme RAI1) (EC 3.6.1.-) (RAT1-interacting protein)

Gene: DXO, RAI1
Organism: Saccharomyces cerevisiae S288C
Interactions: 107
UniProt ID: P53063

Gene Ontology (top 5):
GO:0000166 - nucleotide binding
GO:0000448 - cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000466 - maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000956 - nuclear-transcribed mRNA catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

916860

XRN2
5'-3' exoribonuclease 2

14

4

Small-scale

0.982

High

916863

RT103
Regulator of Ty1 transposition protein 103

2

0

Small-scale

0.736

High

594473

RPB3
DNA-directed RNA polymerase II subunit RPB3

4

0

Small-scale

0.648

High

511234

RL20B
Large ribosomal subunit protein eL20B

3

0

Small-scale

0.613

High

782172

LAS1
Protein LAS1

3

0

Small-scale

0.613

High

712619

RL8B
Large ribosomal subunit protein eL8B

2

1

High-throughput

0.611

High

679883

CDC48
Cell division control protein 48

2

0

High-throughput

0.602

High

804305

SSZ1
Ribosome-associated complex subunit SSZ1

2

2

High-throughput

0.601

High

432638

RL7A
Large ribosomal subunit protein uL30A

2

1

Small-scale

0.584

High

433047

RL6B
Large ribosomal subunit protein eL6B

2

1

Small-scale

0.584

High

601084

RL8A
Large ribosomal subunit protein eL8A

2

1

Small-scale

0.584

High

689081

RL16A
Large ribosomal subunit protein uL13A

2

1

Small-scale

0.584

High

916856

NOP3
Serine/arginine

2

1

Small-scale

0.584

High

916858

RL6A
Large ribosomal subunit protein eL6A

2

1

Small-scale

0.584

High

633491

PP11
Serine/threonine-protein phosphatase PP1-1

2

0

High-throughput

0.563

High

435231

RS3
Small ribosomal subunit protein uS3

2

0

Small-scale

0.559

High

436063

RS13
Small ribosomal subunit protein uS15

2

0

Small-scale

0.559

High

504317

RL31A
Large ribosomal subunit protein eL31A

2

0

High-throughput

0.559

High

512545

RS6A
Small ribosomal subunit protein eS6A

2

0

Small-scale

0.559

High

513115

RS8A
Small ribosomal subunit protein eS8A

2

0

Small-scale

0.559

High

514320

RL12B
Large ribosomal subunit protein uL11B

2

0

Small-scale

0.559

High

515135

RL19B
Large ribosomal subunit protein eL19

2

0

Small-scale

0.559

High

570077

RL3
Large ribosomal subunit protein uL3

2

0

Small-scale

0.559

High

707663

TF2B
Transcription initiation factor IIB

2

0

Small-scale

0.559

High

835840

RL10
Large ribosomal subunit protein uL16

2

0

Small-scale

0.559

High

916857

RS15
Small ribosomal subunit protein uS19

2

0

Small-scale

0.559

High

916866

GRC3
Polynucleotide 5'-hydroxyl-kinase GRC3

2

0

Small-scale

0.559

High

916871

RL13A
Large ribosomal subunit protein eL13A

2

0

Small-scale

0.559

High

570281

RS17B
Small ribosomal subunit protein eS17B

1

1

High-throughput

0.536

High

722104

XPO1
Exportin-1

1

0

High-throughput

0.513

High

602562

PHO85
Cyclin-dependent protein kinase PHO85

1

0

High-throughput

0.480

High

800734

RCK1
Serine/threonine-protein kinase RCK1

1

0

High-throughput

0.480

High

383796

RS17A
Small ribosomal subunit protein eS17A

1

1

High-throughput

0.479

High

409755

RL24A
Large ribosomal subunit protein eL24A

1

1

High-throughput

0.479

High

531812

RL4A
Large ribosomal subunit protein uL4A

1

1

Small-scale

0.479

High

663695

RL24B
Large ribosomal subunit protein eL24B

1

1

High-throughput

0.479

High

689246

RL16B
Large ribosomal subunit protein uL13B

1

1

Small-scale

0.479

High

739414

ZUO1
Zuotin

1

1

High-throughput

0.479

High

741010

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

1

High-throughput

0.479

High

916870

RL7B
Large ribosomal subunit protein uL30B

1

1

High-throughput

0.479

High

149862

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.458

High

383160

RLA4
Large ribosomal subunit protein P2B

1

0

High-throughput

0.458

High

403584

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

0

Small-scale

0.458

High

410236

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.458

High

432879

RL9A
Large ribosomal subunit protein uL6A

1

0

Small-scale

0.458

High

433247

RL17A
Large ribosomal subunit protein uL22A

1

0

Small-scale

0.458

High

433743

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.458

High

434176

RL36A
Large ribosomal subunit protein eL36A

1

0

Small-scale

0.458

High

434264

RL29
Large ribosomal subunit protein eL29

1

0

High-throughput

0.458

High

434407

RL15A
Large ribosomal subunit protein eL15A

1

0

Small-scale

0.458

High

434615

RL22A
Large ribosomal subunit protein eL22A

1

0

High-throughput

0.458

High

436464

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

0

High-throughput

0.458

High

442015

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

455162

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.458

High

482059

C1TM
C-1-tetrahydrofolate synthase, mitochondrial

1

0

High-throughput

0.458

High

503144

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.458

High

503815

RL27A
Large ribosomal subunit protein eL27A

1

0

Small-scale

0.458

High

511453

RL43B
Large ribosomal subunit protein eL43B

1

0

High-throughput

0.458

High

512117

RS4A
Small ribosomal subunit protein eS4A

1

0

Small-scale

0.458

High

513887

RS11B
Small ribosomal subunit protein uS17B

1

0

Small-scale

0.458

High

514031

RL18B
Large ribosomal subunit protein eL18B

1

0

Small-scale

0.458

High

514733

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

569823

RL30
Large ribosomal subunit protein eL30

1

0

Small-scale

0.458

High

579750

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.458

High

624780

PMA2
Plasma membrane ATPase 2

1

0

High-throughput

0.458

High

666504

DBP2
ATP-dependent RNA helicase DBP2

1

0

High-throughput

0.458

High

674727

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

677484

KRR1
KRR1 small subunit processome component

1

0

High-throughput

0.458

High

688922

RS5
Small ribosomal subunit protein uS7

1

0

Small-scale

0.458

High

694595

SPT5
Transcription elongation factor SPT5

1

0

High-throughput

0.458

High

735069

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

745021

YSC84
Protein YSC84

1

0

High-throughput

0.458

High

747477

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.458

High

753477

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.458

High

781224

RL14A
Large ribosomal subunit protein eL14A

1

0

High-throughput

0.458

High

782387

RPF2
Ribosome biogenesis protein RPF2

1

0

High-throughput

0.458

High

790423

GLY1
Low specificity L-threonine aldolase

1

0

High-throughput

0.458

High

792146

GBLP
Small ribosomal subunit protein RACK1

1

0

High-throughput

0.458

High

802279

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

809370

STM1
Suppressor protein STM1

1

0

High-throughput

0.458

High

812492

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

874422

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

916855

NOP15
Ribosome biogenesis protein 15

1

0

High-throughput

0.458

High

916859

RL21A
Large ribosomal subunit protein eL21A

1

0

Small-scale

0.458

High

916862

DHR1
Probable ATP-dependent RNA helicase DHR1

1

0

High-throughput

0.458

High

916867

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.458

High

916868

MLH3
DNA mismatch repair protein MLH3

1

0

High-throughput

0.458

High

916869

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

916872

RL11B
Large ribosomal subunit protein uL5B

1

0

High-throughput

0.458

High

481694

HSP73
Heat shock protein SSA3

1

3

High-throughput

0.445

High

524587

HSP71
Heat shock protein SSA1

1

3

High-throughput

0.445

High

527199

HSP72
Heat shock protein SSA2

1

3

High-throughput

0.445

High

545591

SSB1
Ribosome-associated molecular chaperone SSB1

1

3

High-throughput

0.445

High

819280

SSB2
Ribosome-associated molecular chaperone SSB2

1

3

High-throughput

0.445

High

865949

DPH4
Diphthamide biosynthesis protein 4

1

2

High-throughput

0.445

High

885024

RL4B
Large ribosomal subunit protein uL4B

1

1

High-throughput

0.445

High

676173

MAS5
Mitochondrial protein import protein MAS5

1

0

High-throughput

0.426

High

727184

HS104
Heat shock protein 104

1

0

High-throughput

0.426

High

824491

6P21
6-phosphofructo-2-kinase 1

1

0

High-throughput

0.426

High

916864

BRE1
E3 ubiquitin-protein ligase BRE1

1

0

High-throughput

0.426

High

816312

HSP7E
Heat shock protein SSC3, mitochondrial

1

1

High-throughput

0.407

High

427366

RLA0
Large ribosomal subunit protein uL10

2

0

Small-scale

0.318

High

844538

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.249

Low

877858

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.249

Low

916861

RRP17
Ribosomal RNA-processing protein 17

1

0

High-throughput

0.249

Low

916865

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

916765

ERG25
C-4 methylsterol oxidase ERG25

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025