Protein: RRP15
Ribosomal RNA-processing protein 15

Gene: RRP15
Organism: Saccharomyces cerevisiae S288C
Interactions: 105
UniProt ID: Q06511

Gene Ontology (top 5):
GO:0000460 - maturation of 5.8S rRNA
GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000466 - maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000470 - maturation of LSU-rRNA
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

804669

SSF1
Ribosome biogenesis protein SSF1

5

1

High-throughput

0.920

High

1055483

SSF2
Ribosome biogenesis protein SSF2

4

1

High-throughput

0.904

High

782456

RPF2
Ribosome biogenesis protein RPF2

4

0

Small-scale

0.836

High

805098

RPF1
Ribosome production factor 1

3

0

Small-scale

0.775

High

1055476

BRX1
Ribosome biogenesis protein BRX1

2

4

Small-scale

0.754

High

633195

MAK11
Protein MAK11

4

1

Small-scale

0.696

High

1043292

HAS1
ATP-dependent RNA helicase HAS1

4

2

Small-scale

0.676

High

919007

PESC
Pescadillo homolog

4

0

High-throughput

0.657

High

827617

RLP7
Ribosome biogenesis protein RLP7

4

0

Small-scale

0.648

High

917564

NSA1
Ribosome biogenesis protein NSA1

4

0

Small-scale

0.648

High

1055484

MAK21
Ribosome biogenesis protein MAK21

2

2

High-throughput

0.634

High

1039637

NOG1
Nucleolar GTP-binding protein 1

3

0

Small-scale

0.613

High

586029

CSK21
Casein kinase II subunit alpha

2

0

Small-scale

0.585

High

682393

SPB4
ATP-dependent rRNA helicase SPB4

2

2

High-throughput

0.584

High

1055471

RRP15
Ribosomal RNA-processing protein 15

2

0

High-throughput

0.569

High

763124

RRP1
Ribosomal RNA-processing protein 1

2

0

Small-scale

0.559

High

814394

NOC2
Nucleolar complex protein 2

2

0

High-throughput

0.559

High

816801

NOP16
Nucleolar protein 16

2

0

Small-scale

0.559

High

830188

NOP2
25S rRNA

2

0

Small-scale

0.559

High

850021

LOC1
60S ribosomal subunit assembly/export protein LOC1

2

0

Small-scale

0.559

High

924853

NOP15
Ribosome biogenesis protein 15

2

0

High-throughput

0.559

High

1044903

RRP17
Ribosomal RNA-processing protein 17

2

0

High-throughput

0.559

High

1046521

PUF6
Pumilio homology domain family member 6

2

0

Small-scale

0.559

High

1055486

DBP10
ATP-dependent RNA helicase DBP10

2

0

High-throughput

0.559

High

1055489

IF6
Eukaryotic translation initiation factor 6

2

0

Small-scale

0.559

High

722281

XPO1
Exportin-1

1

0

High-throughput

0.513

High

763028

SPT7
SAGA complex subunit SPT7

1

0

High-throughput

0.513

High

893344

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

0

High-throughput

0.513

High

441263

KAPA
cAMP-dependent protein kinase type 1

1

0

High-throughput

0.480

High

448810

SNF1
Carbon catabolite-derepressing protein kinase

1

0

High-throughput

0.480

High

656633

KC11
Casein kinase I homolog 1

1

0

High-throughput

0.480

High

531902

RL4A
Large ribosomal subunit protein uL4A

1

1

Small-scale

0.479

High

601136

RL8A
Large ribosomal subunit protein eL8A

1

1

Small-scale

0.479

High

689143

RL16A
Large ribosomal subunit protein uL13A

1

1

Small-scale

0.479

High

689286

RL16B
Large ribosomal subunit protein uL13B

1

1

Small-scale

0.479

High

712675

RL8B
Large ribosomal subunit protein eL8B

1

1

Small-scale

0.479

High

746677

DRS1
ATP-dependent RNA helicase DRS1

1

1

High-throughput

0.479

High

807154

FKBP3
Peptidyl-prolyl cis-trans isomerase

1

1

High-throughput

0.479

High

823047

ATAD2
ATPase histone chaperone YTA7

1

1

High-throughput

0.479

High

885093

RL4B
Large ribosomal subunit protein uL4B

1

1

Small-scale

0.479

High

932183

RL15B
Large ribosomal subunit protein eL15B

1

1

Small-scale

0.479

High

1054249

FKBP4
FK506-binding protein 4

1

1

High-throughput

0.479

High

1054403

DBP9
ATP-dependent RNA helicase DBP9

1

1

High-throughput

0.479

High

1055472

NOC4
Nucleolar complex protein 4

1

2

High-throughput

0.479

High

1055473

NOC3
Nucleolar complex-associated protein 3

1

1

High-throughput

0.479

High

1055475

NOP12
Nucleolar protein 12

1

1

High-throughput

0.479

High

1055487

NOP56
Nucleolar protein 56

1

1

Small-scale

0.479

High

1055488

NOP58
Nucleolar protein 58

1

1

High-throughput

0.479

High

1046711

SPC24
Kinetochore protein SPC24

1

0

High-throughput

0.460

High

1055485

SMT3
Ubiquitin-like protein SMT3

1

0

High-throughput

0.460

High

149968

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.458

High

433299

RL17A
Large ribosomal subunit protein uL22A

1

0

Small-scale

0.458

High

512667

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.458

High

534148

MAK16
Protein MAK16

1

0

High-throughput

0.458

High

585386

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

0

Small-scale

0.458

High

646544

RAD53
Serine/threonine-protein kinase RAD53

1

0

High-throughput

0.458

High

661565

PSA2
Proteasome subunit alpha type-2

1

0

High-throughput

0.458

High

677243

SPB1
27S pre-rRNA

1

0

High-throughput

0.458

High

677969

YCQ6
Uncharacterized protein YCR016W

1

0

High-throughput

0.458

High

680087

CDC48
Cell division control protein 48

1

0

High-throughput

0.458

High

684851

RL5
Large ribosomal subunit protein uL18

1

0

Small-scale

0.458

High

689679

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

708273

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

750152

MRT4
Ribosome assembly factor MRT4

1

0

High-throughput

0.458

High

780326

EBP2
rRNA-processing protein EBP2

1

0

High-throughput

0.458

High

780710

RRP14
Ribosomal RNA-processing protein 14

1

0

High-throughput

0.458

High

795847

YBC8
UPF0642 protein YBL028C

1

0

High-throughput

0.458

High

798322

ENP1
Essential nuclear protein 1

1

0

High-throughput

0.458

High

803943

CIC1
Proteasome-interacting protein CIC1

1

0

High-throughput

0.458

High

816909

NUG1
Nuclear GTP-binding protein NUG1

1

0

High-throughput

0.458

High

818279

NSA2
Ribosome biogenesis protein NSA2

1

0

High-throughput

0.458

High

820397

RIO2
Serine/threonine-protein kinase RIO2

1

0

High-throughput

0.458

High

844625

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.458

High

924336

NOP13
Nucleolar protein 13

1

0

High-throughput

0.458

High

925080

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.458

High

1046043

DHR1
Probable ATP-dependent RNA helicase DHR1

1

0

High-throughput

0.458

High

1046119

RRB1
Ribosome assembly protein RRB1

1

0

High-throughput

0.458

High

1047286

ERB1
Ribosome biogenesis protein ERB1

1

0

High-throughput

0.458

High

1053971

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

1054364

JIP5
WD repeat-containing protein JIP5

1

0

High-throughput

0.458

High

1055474

RLP24
Ribosome biogenesis protein RLP24

1

0

High-throughput

0.458

High

1055477

SGO1
Shugoshin

1

0

High-throughput

0.458

High

1055480

RRS1
Regulator of ribosome biosynthesis

1

0

High-throughput

0.458

High

1055481

NIP7
60S ribosome subunit biogenesis protein NIP7

1

0

High-throughput

0.458

High

1055482

YTM1
Ribosome biogenesis protein YTM1

1

0

High-throughput

0.458

High

433082

RL6B
Large ribosomal subunit protein eL6B

1

1

Small-scale

0.437

High

434447

RL15A
Large ribosomal subunit protein eL15A

1

1

Small-scale

0.437

High

1036297

RL6A
Large ribosomal subunit protein eL6A

1

1

Small-scale

0.437

High

806998

2A5D
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

1

0

High-throughput

0.426

High

898197

SPT20
SAGA complex subunit SPT20

1

0

High-throughput

0.426

High

1055478

HRK1
Serine/threonine-protein kinase HRK1

1

0

High-throughput

0.279

Low

922125

COPA
Coatomer subunit alpha

1

0

High-throughput

0.269

Low

917181

ATG1
Serine/threonine-protein kinase ATG1

1

0

High-throughput

0.261

Low

433862

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.249

Low

503257

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

513236

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

570153

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.249

Low

778548

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.249

Low

795234

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

802402

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.249

Low

812683

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

1033582

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.249

Low

1046310

VMS1
tRNA endonuclease VMS1

1

0

High-throughput

0.249

Low

1055479

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025