Protein: PYGO2
Pygopus homolog 2

Gene: PYGO2
Organism: Homo sapiens
Interactions: 47
UniProt ID: Q9BRQ0

Gene Ontology (top 5):
GO:0001822 - kidney development
GO:0002088 - lens development in camera-type eye
GO:0003682 - chromatin binding
GO:0005654 - nucleoplasm
GO:0007289 - spermatid nucleus differentiation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

131740

BCL9
B-cell CLL/lymphoma 9 protein

4

3

Small-scale

0.691

High

152683

KMT2D
Histone-lysine N-methyltransferase 2D

1

0

Small-scale

0.687

High

1270780

CBP
CREB-binding protein

1

0

Small-scale

0.687

High

1271445

KAT2A
Histone acetyltransferase KAT2A

1

0

Small-scale

0.687

High

1200128

BCL9L
B-cell CLL/lymphoma 9-like protein

2

3

High-throughput

0.628

High

1310378

PYGO2
Pygopus homolog 2

1

0

Small-scale

0.586

High

1070764

RBBP5
Retinoblastoma-binding protein 5

1

1

Small-scale

0.561

High

682003

AKT1
RAC-alpha serine/threonine-protein kinase

1

0

Small-scale

0.537

High

903474

WDR5
WD repeat-containing protein 5

1

0

Small-scale

0.537

High

1082357

DDB1
DNA damage-binding protein 1

1

0

Small-scale

0.537

High

1310379

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

1

0

Small-scale

0.537

High

1310385

DCAF1
DDB1- and CUL4-associated factor 1

1

1

Small-scale

0.501

High

266500

SUPT3
Transcription initiation protein SPT3 homolog

1

0

Small-scale

0.480

High

1310384

TRRAP
Transformation/transcription domain-associated protein

1

0

Small-scale

0.480

High

211949

TLX3
T-cell leukemia homeobox protein 3

1

6

High-throughput

0.479

High

507497

ERG
Transcriptional regulator ERG

1

1

High-throughput

0.479

High

717315

CTNB1
Catenin beta-1

1

2

Small-scale

0.479

High

727912

SOX6
Transcription factor SOX-6

1

2

High-throughput

0.479

High

794564

ETV4
ETS translocation variant 4

1

1

High-throughput

0.479

High

818409

SOX2
Transcription factor SOX-2

1

2

High-throughput

0.479

High

822670

LHX1
LIM/homeobox protein Lhx1

1

10

High-throughput

0.479

High

878458

PAX9
Paired box protein Pax-9

1

2

High-throughput

0.479

High

980857

TLE3
Transducin-like enhancer protein 3

1

1

High-throughput

0.479

High

988797

PAX8
Paired box protein Pax-8

1

2

High-throughput

0.479

High

1148487

LHX8
LIM/homeobox protein Lhx8

1

11

High-throughput

0.479

High

1254904

SP7
Transcription factor Sp7

1

2

High-throughput

0.479

High

487722

ANDR
Androgen receptor

1

0

High-throughput

0.458

High

505283

EGR2
E3 SUMO-protein ligase EGR2

1

0

High-throughput

0.458

High

1043194

CUL4A
Cullin-4A

1

0

Small-scale

0.458

High

1071069

IRF4
Interferon regulatory factor 4

1

0

High-throughput

0.458

High

1085178

TBR1
T-box brain protein 1

1

0

High-throughput

0.458

High

1244677

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.458

High

1310382

KLF15
Krueppel-like factor 15

1

0

High-throughput

0.458

High

197816

CRX
Cone-rod homeobox protein

1

6

High-throughput

0.437

High

213376

TLX2
T-cell leukemia homeobox protein 2

1

3

High-throughput

0.437

High

269575

JERKY
Jerky protein homolog

1

1

Small-scale

0.437

High

620196

PAX7
Paired box protein Pax-7

1

5

High-throughput

0.437

High

679163

TLX1
T-cell leukemia homeobox protein 1

1

3

High-throughput

0.437

High

727793

SOX5
Transcription factor SOX-5

1

2

High-throughput

0.437

High

1281174

LHX4
LIM/homeobox protein Lhx4

1

11

High-throughput

0.437

High

1310381

LHX3
LIM/homeobox protein Lhx3

1

11

High-throughput

0.437

High

1158309

CDC73
Parafibromin

1

0

Small-scale

0.426

High

888208

TPIS
Triosephosphate isomerase

1

0

High-throughput

0.279

Low

1310380

GRHPR
Glyoxylate reductase/hydroxypyruvate reductase

1

0

High-throughput

0.279

Low

1310383

SORC3
VPS10 domain-containing receptor SorCS3

1

0

High-throughput

0.268

Low

719600

MERL
Merlin

1

0

Small-scale

0.261

Low


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Last updated: 15 Jul 2024