Protein: EPN2
Epsin-2 (EPS-15-interacting protein 2)

Gene: EPN2
Organism: Homo sapiens
Interactions: 89
UniProt ID: O95208

Gene Ontology (top 5):
GO:0005543 - phospholipid binding
GO:0005768 - endosome
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0006897 - endocytosis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

307564

EPN3
Epsin-3

3

13

High-throughput

0.861

High

307500

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

6

19

Small-scale

0.735

High

307506

1433T
14-3-3 protein theta

3

17

High-throughput

0.650

High

307525

1433Z
14-3-3 protein zeta/delta

3

17

High-throughput

0.650

High

307553

WBP2
WW domain-binding protein 2

3

0

Small-scale

0.626

High

307522

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

2

13

High-throughput

0.614

High

307497

CLCA
Clathrin light chain A

2

10

High-throughput

0.611

High

307509

EPHA2
Ephrin type-A receptor 2

2

5

High-throughput

0.611

High

175627

TRI18
E3 ubiquitin-protein ligase Midline-1

2

11

High-throughput

0.606

High

282444

RNF8
E3 ubiquitin-protein ligase RNF8

2

5

High-throughput

0.606

High

307511

TRI23
E3 ubiquitin-protein ligase TRIM23

2

8

High-throughput

0.606

High

307513

TXLNA
Alpha-taxilin

2

5

High-throughput

0.606

High

307523

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

2

9

High-throughput

0.606

High

307528

TRI26
Tripartite motif-containing protein 26

2

3

High-throughput

0.606

High

307532

SMAD1
Mothers against decapentaplegic homolog 1

2

3

High-throughput

0.606

High

307542

FANCM
Fanconi anemia group M protein

2

4

High-throughput

0.606

High

307546

ARRD1
Arrestin domain-containing protein 1

2

5

High-throughput

0.606

High

307547

ARRD2
Arrestin domain-containing protein 2

2

5

High-throughput

0.606

High

307554

PMEPA
Protein TMEPAI

2

1

High-throughput

0.606

High

307555

ARRD3
Arrestin domain-containing protein 3

2

5

High-throughput

0.606

High

307560

LITAF
Lipopolysaccharide-induced tumor necrosis factor-alpha factor

2

4

High-throughput

0.606

High

307561

TRI62
E3 ubiquitin-protein ligase TRIM62

2

3

High-throughput

0.606

High

307510

1433B
14-3-3 protein beta/alpha

2

17

High-throughput

0.601

High

307520

1433G
14-3-3 protein gamma

2

17

High-throughput

0.601

High

307527

1433F
14-3-3 protein eta

2

17

High-throughput

0.601

High

307529

PICAL
Phosphatidylinositol-binding clathrin assembly protein

1

14

High-throughput

0.590

High

307521

RHOB
Rho-related GTP-binding protein RhoB

2

10

High-throughput

0.584

High

307515

THOP1
Thimet oligopeptidase

2

0

High-throughput

0.580

High

307516

ATX1
Ataxin-1

2

0

High-throughput

0.580

High

307517

AAPK2
5'-AMP-activated protein kinase catalytic subunit alpha-2

2

0

High-throughput

0.580

High

307519

EIF3E
Eukaryotic translation initiation factor 3 subunit E

2

0

High-throughput

0.580

High

307535

MAR1
Melanoma antigen recognized by T-cells 1

2

0

High-throughput

0.580

High

307540

PP4P1
Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase

2

0

High-throughput

0.580

High

307543

SPART
Spartin

2

0

High-throughput

0.580

High

307496

ESR1
Estrogen receptor

2

17

High-throughput

0.571

High

307530

DAZP2
DAZ-associated protein 2

2

3

High-throughput

0.553

High

307550

F168A
Protein FAM168A

2

2

High-throughput

0.553

High

307556

PKHB2
Pleckstrin homology domain-containing family B member 2

2

1

High-throughput

0.553

High

307557

WBP1
WW domain-binding protein 1

2

1

High-throughput

0.553

High

307565

CDIP1
Cell death-inducing p53-target protein 1

2

4

High-throughput

0.553

High

307567

WBP1L
WW domain binding protein 1-like

2

1

High-throughput

0.553

High

307570

TRIM1
Probable E3 ubiquitin-protein ligase MID2

2

11

High-throughput

0.553

High

307499

PARP1
Poly [ADP-ribose] polymerase 1

1

7

High-throughput

0.536

High

307508

SMCA1
Probable global transcription activator SNF2L1

1

3

High-throughput

0.536

High

307549

H1X
Histone H1.10

1

1

High-throughput

0.536

High

307568

GTSE1
G2 and S phase-expressed protein 1

1

3

High-throughput

0.536

High

307526

CLH1
Clathrin heavy chain 1

1

15

Small-scale

0.501

High

307558

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

5

High-throughput

0.500

High

47730

RBM47
RNA-binding protein 47

1

3

High-throughput

0.489

High

307491

NSD2
Histone-lysine N-methyltransferase NSD2

1

5

High-throughput

0.489

High

307536

H2A2A
Histone H2A type 2-A

1

2

High-throughput

0.489

High

307552

RAD50
DNA repair protein RAD50

1

5

High-throughput

0.489

High

307495

APOE
Apolipoprotein E

1

1

High-throughput

0.481

High

307533

ITSN1
Intersectin-1

1

15

High-throughput

0.481

High

178340

STX7
Syntaxin-7

1

4

High-throughput

0.479

High

204865

TGON2
Trans-Golgi network integral membrane protein 2

1

4

High-throughput

0.479

High

212702

STX6
Syntaxin-6

1

4

High-throughput

0.479

High

307490

DIRA3
GTP-binding protein Di-Ras3

1

3

High-throughput

0.479

High

307492

EGFR
Epidermal growth factor receptor

1

7

High-throughput

0.479

High

307493

RASH
GTPase HRas

1

9

High-throughput

0.479

High

307494

RASK
GTPase KRas

1

10

High-throughput

0.479

High

307498

CLCB
Clathrin light chain B

1

10

High-throughput

0.479

High

307501

LAMP1
Lysosome-associated membrane glycoprotein 1

1

5

High-throughput

0.479

High

307502

FGFR1
Fibroblast growth factor receptor 1

1

19

High-throughput

0.479

High

307503

CADH1
Cadherin-1

1

3

High-throughput

0.479

High

307504

CXA1
Gap junction alpha-1 protein

1

3

High-throughput

0.479

High

307505

FGFR4
Fibroblast growth factor receptor 4

1

19

High-throughput

0.479

High

307514

OPRD
Delta-type opioid receptor

1

2

Small-scale

0.479

High

307518

H2B1D
Histone H2B type 1-D

1

7

High-throughput

0.479

High

307524

AP2B1
AP-2 complex subunit beta

1

20

High-throughput

0.479

High

307531

RBP1
RalA-binding protein 1

1

5

Small-scale

0.479

High

307537

LTOR1
Ragulator complex protein LAMTOR1

1

3

High-throughput

0.479

High

307539

ATG9A
Autophagy-related protein 9A

1

2

High-throughput

0.479

High

307544

CXD3
Gap junction delta-3 protein

1

3

High-throughput

0.479

High

307545

RHG18
Rho GTPase-activating protein 18

1

3

High-throughput

0.479

High

307548

SMAP2
Stromal membrane-associated protein 2

1

3

High-throughput

0.479

High

307551

ESR2
Estrogen receptor beta

1

16

High-throughput

0.479

High

307566

BACD3
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3

1

4

Small-scale

0.479

High

307569

UBQL2
Ubiquilin-2

1

8

Small-scale

0.479

High

307571

MYO6
Unconventional myosin-VI

1

4

High-throughput

0.479

High

307507

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.458

High

307559

RAB3I
Rab-3A-interacting protein

1

0

High-throughput

0.458

High

307563

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.458

High

307534

EREP1
Endosomal transmembrane epsin interactor 1

1

2

Small-scale

0.457

High

307512

GRP75
Stress-70 protein, mitochondrial

1

2

High-throughput

0.437

High

307538

TRI67
Tripartite motif-containing protein 67

1

12

High-throughput

0.437

High

307541

TMM17
Transmembrane protein 17

1

2

High-throughput

0.437

High

307562

LFG2
Protein lifeguard 2

2

0

High-throughput

0.316

High

132395

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024