Protein: TOIP1
Torsin-1A-interacting protein 1 (Lamin-associated protein 1B) (LAP1B)

Gene: TOIP1, TOR1AIP1
Organism: Homo sapiens
Interactions: 231
UniProt ID: Q5JTV8

Gene Ontology (top 5):
GO:0001671 - ATPase activator activity
GO:0005521 - lamin binding
GO:0005634 - nucleus
GO:0005635 - nuclear envelope
GO:0005637 - nuclear inner membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

160714

TOR1A
Torsin-1A

6

4

Small-scale

0.956

High

385820

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

7

3

Small-scale

0.738

High

348540

AIFM1
Apoptosis-inducing factor 1, mitochondrial

4

0

High-throughput

0.670

High

786649

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

3

3

Small-scale

0.670

High

1206881

KLH15
Kelch-like protein 15

3

0

High-throughput

0.634

High

1206905

CAH10
Carbonic anhydrase-related protein 10

4

1

High-throughput

0.630

High

528271

THIO
Thioredoxin

2

1

High-throughput

0.628

High

160819

TOR1B
Torsin-1B

1

4

Small-scale

0.618

High

1206826

TOR2A
Torsin-2A

1

4

Small-scale

0.618

High

1206895

TOR3A
Torsin-3A

1

4

Small-scale

0.618

High

967782

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

2

3

Small-scale

0.614

High

698743

CALX
Calnexin

2

4

High-throughput

0.611

High

1099695

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

2

0

High-throughput

0.602

High

1136736

MD2BP
MAD2L1-binding protein

2

0

High-throughput

0.602

High

1004081

CXAR
Coxsackievirus and adenovirus receptor

1

0

High-throughput

0.586

High

1206825

TOIP1
Torsin-1A-interacting protein 1

1

0

High-throughput

0.586

High

218276

TGON2
Trans-Golgi network integral membrane protein 2

2

0

High-throughput

0.559

High

980825

H2B1C
Histone H2B type 1-C/E/F/G/I

2

0

High-throughput

0.559

High

1206921

UBQL2
Ubiquilin-2

2

0

High-throughput

0.559

High

1206910

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.549

High

1038308

MP2K1
Dual specificity mitogen-activated protein kinase kinase 1

2

0

High-throughput

0.547

High

955262

CDC42
Cell division control protein 42 homolog

2

7

High-throughput

0.543

High

170795

CLGN
Calmegin

1

4

High-throughput

0.536

High

1118488

TBB2A
Tubulin beta-2A chain

1

2

High-throughput

0.536

High

1206851

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

1

High-throughput

0.536

High

375585

RASK
GTPase KRas

2

3

High-throughput

0.533

High

540485

LAMP1
Lysosome-associated membrane glycoprotein 1

2

2

High-throughput

0.533

High

720251

UFO
Tyrosine-protein kinase receptor UFO

2

4

Small-scale

0.533

High

951193

SC61B
Protein transport protein Sec61 subunit beta

2

1

High-throughput

0.533

High

1149899

TERF2
Telomeric repeat-binding factor 2

1

0

High-throughput

0.529

High

845673

MUC18
Cell surface glycoprotein MUC18

1

0

High-throughput

0.517

High

317183

UBP1
Ubiquitin carboxyl-terminal hydrolase 1

1

0

High-throughput

0.513

High

761702

HSP74
Heat shock 70 kDa protein 4

1

0

High-throughput

0.513

High

776969

PPM1A
Protein phosphatase 1A

1

0

High-throughput

0.513

High

876690

HSP13
Heat shock 70 kDa protein 13

1

0

High-throughput

0.513

High

997767

CSK21
Casein kinase II subunit alpha

1

0

High-throughput

0.513

High

1047023

IF4G1
Eukaryotic translation initiation factor 4 gamma 1

1

0

High-throughput

0.513

High

1161105

MK06
Mitogen-activated protein kinase 6

1

0

High-throughput

0.513

High

1206868

IPO4
Importin-4

1

0

High-throughput

0.513

High

1206909

MIC19
MICOS complex subunit MIC19

1

0

High-throughput

0.513

High

1206917

CSN7A
COP9 signalosome complex subunit 7a

1

0

High-throughput

0.513

High

1206922

GT2D1
General transcription factor II-I repeat domain-containing protein 1

1

0

High-throughput

0.513

High

1206923

NARF
Nuclear prelamin A recognition factor

1

0

High-throughput

0.513

High

250647

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

0

High-throughput

0.493

High

1054599

PSME1
Proteasome activator complex subunit 1

1

0

High-throughput

0.493

High

1111035

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.493

High

1206869

ZN296
Zinc finger protein 296

1

0

High-throughput

0.493

High

1206906

BRWD1
Bromodomain and WD repeat-containing protein 1

1

0

High-throughput

0.493

High

1127913

PDIA5
Protein disulfide-isomerase A5

1

1

High-throughput

0.489

High

1194681

GXLT1
Glucoside xylosyltransferase 1

1

1

High-throughput

0.489

High

1206831

GL8D1
Glycosyltransferase 8 domain-containing protein 1

1

1

High-throughput

0.489

High

1206899

PEAK1
Inactive tyrosine-protein kinase PEAK1

1

1

High-throughput

0.489

High

185757

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

0

High-throughput

0.480

High

363390

EGFR
Epidermal growth factor receptor

1

3

High-throughput

0.479

High

466297

RHOC
Rho-related GTP-binding protein RhoC

1

6

High-throughput

0.479

High

581093

RAC2
Ras-related C3 botulinum toxin substrate 2

1

6

High-throughput

0.479

High

604019

CXA1
Gap junction alpha-1 protein

1

1

High-throughput

0.479

High

631266

RAB5A
Ras-related protein Rab-5A

1

2

High-throughput

0.479

High

634472

LMNB1
Lamin-B1

1

3

High-throughput

0.479

High

962133

RHOA
Transforming protein RhoA

1

7

High-throughput

0.479

High

988421

RAC1
Ras-related C3 botulinum toxin substrate 1

1

7

High-throughput

0.479

High

1206832

RNF43
E3 ubiquitin-protein ligase RNF43

1

1

High-throughput

0.479

High

1206834

TECT3
Tectonic-3

1

2

High-throughput

0.479

High

1206843

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

2

High-throughput

0.479

High

1206871

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

1206873

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

1

High-throughput

0.479

High

1206879

DNJC1
DnaJ homolog subfamily C member 1

1

4

High-throughput

0.479

High

1206880

CALR3
Calreticulin-3

1

4

High-throughput

0.479

High

1206884

ERGI2
Endoplasmic reticulum-Golgi intermediate compartment protein 2

1

1

High-throughput

0.479

High

1206907

T106B
Transmembrane protein 106B

1

1

High-throughput

0.479

High

129154

MEN1
Menin

1

0

High-throughput

0.458

High

226057

STX6
Syntaxin-6

1

0

High-throughput

0.458

High

241902

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

274613

DNJB6
DnaJ homolog subfamily B member 6

1

0

High-throughput

0.458

High

291367

NU155
Nuclear pore complex protein Nup155

1

0

High-throughput

0.458

High

535153

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.458

High

588865

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

605707

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

0

High-throughput

0.458

High

606841

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.458

High

695641

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

715619

MARCS
Myristoylated alanine-rich C-kinase substrate

1

0

High-throughput

0.458

High

768365

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

837653

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

0

High-throughput

0.458

High

883565

CENPA
Histone H3-like centromeric protein A

1

0

High-throughput

0.458

High

894797

EMD
Emerin

1

0

High-throughput

0.458

High

979782

H4
Histone H4

1

0

High-throughput

0.458

High

1097331

CBX3
Chromobox protein homolog 3

1

0

High-throughput

0.458

High

1106938

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

1115239

CUL4B
Cullin-4B

1

0

High-throughput

0.458

High

1156736

E2F4
Transcription factor E2F4

1

0

High-throughput

0.458

High

1161478

IF16
Gamma-interferon-inducible protein 16

1

0

High-throughput

0.458

High

1206833

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

1206838

SYNE3
Nesprin-3

1

0

High-throughput

0.458

High

1206841

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1206842

SLN11
Schlafen family member 11

1

0

High-throughput

0.458

High

1206844

LBN
Limbin

1

0

High-throughput

0.458

High

1206845

DTX2
Probable E3 ubiquitin-protein ligase DTX2

1

0

High-throughput

0.458

High

1206846

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

1206847

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

0

Small-scale

0.458

High

1206850

TEX2
Testis-expressed protein 2

1

0

High-throughput

0.458

High

1206853

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

1206862

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.458

High

1206867

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

1206876

LRC59
Leucine-rich repeat-containing protein 59

1

0

High-throughput

0.458

High

1206885

RMD3
Regulator of microtubule dynamics protein 3

1

0

High-throughput

0.458

High

1206889

DERL1
Derlin-1

1

0

High-throughput

0.458

High

1206890

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.458

High

1206892

CCDC8
Coiled-coil domain-containing protein 8

1

0

High-throughput

0.458

High

1206898

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1206908

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.458

High

1206912

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

1206913

VAPA
Vesicle-associated membrane protein-associated protein A

1

0

High-throughput

0.458

High

1206916

DJB11
DnaJ homolog subfamily B member 11

1

0

High-throughput

0.458

High

1206919

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1206828

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

1

High-throughput

0.445

High

48654

ESYT2
Extended synaptotagmin-2

1

1

High-throughput

0.437

High

126634

RHOD
Rho-related GTP-binding protein RhoD

1

9

High-throughput

0.437

High

189609

STX7
Syntaxin-7

1

1

High-throughput

0.437

High

341071

DIRA3
GTP-binding protein Di-Ras3

1

1

High-throughput

0.437

High

373974

RASN
GTPase NRas

1

3

High-throughput

0.437

High

412053

NTRK1
High affinity nerve growth factor receptor

1

5

High-throughput

0.437

High

439757

INSR
Insulin receptor

1

5

High-throughput

0.437

High

460833

CATB
Cathepsin B

1

1

High-throughput

0.437

High

463982

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

3

High-throughput

0.437

High

465542

IGF1R
Insulin-like growth factor 1 receptor

1

6

High-throughput

0.437

High

562103

LAMP2
Lysosome-associated membrane glycoprotein 2

1

2

High-throughput

0.437

High

630536

RAB3B
Ras-related protein Rab-3B

1

1

High-throughput

0.437

High

630825

RAB4A
Ras-related protein Rab-4A

1

1

High-throughput

0.437

High

710715

EPHA8
Ephrin type-A receptor 8

1

3

High-throughput

0.437

High

900851

RAB5C
Ras-related protein Rab-5C

1

2

High-throughput

0.437

High

901287

RAB7A
Ras-related protein Rab-7a

1

3

High-throughput

0.437

High

901853

RAB9A
Ras-related protein Rab-9A

1

3

High-throughput

0.437

High

910085

RND2
Rho-related GTP-binding protein RhoN

1

9

High-throughput

0.437

High

953488

RAC3
Ras-related C3 botulinum toxin substrate 3

1

7

High-throughput

0.437

High

1015496

RHOG
Rho-related GTP-binding protein RhoG

1

6

High-throughput

0.437

High

1058453

CKAP4
Cytoskeleton-associated protein 4

1

1

High-throughput

0.437

High

1087138

STX4
Syntaxin-4

1

1

High-throughput

0.437

High

1098413

DNJC3
DnaJ homolog subfamily C member 3

1

3

High-throughput

0.437

High

1144939

RAB35
Ras-related protein Rab-35

1

1

High-throughput

0.437

High

1156967

NTRK3
NT-3 growth factor receptor

1

5

High-throughput

0.437

High

1163352

CAH9
Carbonic anhydrase 9

1

1

High-throughput

0.437

High

1179094

TECT1
Tectonic-1

1

2

High-throughput

0.437

High

1206827

EPHAA
Ephrin type-A receptor 10

1

3

High-throughput

0.437

High

1206835

RHDF2
Inactive rhomboid protein 2

1

1

High-throughput

0.437

High

1206852

MIRO2
Mitochondrial Rho GTPase 2

1

11

High-throughput

0.437

High

1206854

CXD3
Gap junction delta-3 protein

1

1

High-throughput

0.437

High

1206857

DJC22
DnaJ homolog subfamily C member 22

1

1

High-throughput

0.437

High

1206861

RN149
E3 ubiquitin-protein ligase RNF149

1

2

High-throughput

0.437

High

1206865

RHBL4
Rhomboid-related protein 4

1

1

High-throughput

0.437

High

1206878

TECT2
Tectonic-2

1

2

High-throughput

0.437

High

1206888

ESYT1
Extended synaptotagmin-1

1

1

High-throughput

0.437

High

1206893

DJC25
DnaJ homolog subfamily C member 25

1

3

High-throughput

0.437

High

1206896

RHOJ
Rho-related GTP-binding protein RhoJ

1

7

High-throughput

0.437

High

1206901

RHOF
Rho-related GTP-binding protein RhoF

1

8

High-throughput

0.437

High

1206920

SEC63
Translocation protein SEC63 homolog

1

1

High-throughput

0.437

High

1206925

ALK
ALK tyrosine kinase receptor

1

5

High-throughput

0.437

High

1206926

LAMP3
Lysosome-associated membrane glycoprotein 3

1

2

High-throughput

0.437

High

1206927

DJC16
DnaJ homolog subfamily C member 16

1

2

High-throughput

0.437

High

1206929

ARL5A
ADP-ribosylation factor-like protein 5A

1

1

High-throughput

0.437

High

841189

CNDD3
Condensin-2 complex subunit D3

1

0

High-throughput

0.426

High

877673

SL9A3
Sodium/hydrogen exchanger 3

1

1

High-throughput

0.407

High

1197782

S39AC
Zinc transporter ZIP12

1

4

High-throughput

0.407

High

1206830

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.407

High

1206918

SL9A2
Sodium/hydrogen exchanger 2

1

1

High-throughput

0.407

High

1206856

MIA40
Mitochondrial intermembrane space import and assembly protein 40

3

0

High-throughput

0.345

High

417481

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

2

0

High-throughput

0.318

High

418186

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

2

0

High-throughput

0.318

High

975072

ARF6
ADP-ribosylation factor 6

2

0

High-throughput

0.305

High

976313

RB11A
Ras-related protein Rab-11A

2

0

High-throughput

0.305

High

505166

OST4
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4

1

0

High-throughput

0.279

Low

813117

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

0

High-throughput

0.279

Low

932473

KAD2
Adenylate kinase 2, mitochondrial

1

0

High-throughput

0.279

Low

1126231

PDE3A
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A

1

0

High-throughput

0.279

Low

1206858

MREG
Melanoregulin

1

0

High-throughput

0.279

Low

1206864

STT3B
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B

1

0

High-throughput

0.279

Low

1206866

GPX8
Probable glutathione peroxidase 8

1

0

High-throughput

0.279

Low

1206872

PIGT
GPI-anchor transamidase component PIGT

1

0

High-throughput

0.279

Low

1206874

CCD47
PAT complex subunit CCDC47

1

0

High-throughput

0.279

Low

1206877

ATG4C
Cysteine protease ATG4C

1

0

High-throughput

0.279

Low

1206887

ADPGK
ADP-dependent glucokinase

1

0

High-throughput

0.279

Low

1206891

MAGT1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1

1

0

High-throughput

0.279

Low

1206924

FBX2
F-box only protein 2

1

0

High-throughput

0.279

Low

1206928

EMC9
ER membrane protein complex subunit 9

1

0

High-throughput

0.279

Low

680714

CATS
Cathepsin S

1

0

High-throughput

0.269

Low

1193228

SPAS1
Spermatogenesis-associated serine-rich protein 1

1

0

High-throughput

0.268

Low

1206855

AGGF1
Angiogenic factor with G patch and FHA domains 1

1

0

High-throughput

0.268

Low

157463

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.249

Low

173945

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

0

High-throughput

0.249

Low

229728

CALU
Calumenin

1

0

High-throughput

0.249

Low

293804

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

377598

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low

548341

CP2C9
Cytochrome P450 2C9

1

0

High-throughput

0.249

Low

566701

PDIA4
Protein disulfide-isomerase A4

1

0

High-throughput

0.249

Low

611162

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

0

High-throughput

0.249

Low

692991

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.249

Low

821393

TCPZ
T-complex protein 1 subunit zeta

1

0

High-throughput

0.249

Low

847555

SSRA
Translocon-associated protein subunit alpha

1

0

High-throughput

0.249

Low

880571

LMAN1
Protein ERGIC-53

1

0

High-throughput

0.249

Low

903949

BAP31
B-cell receptor-associated protein 31

1

0

High-throughput

0.249

Low

1027031

REEP5
Receptor expression-enhancing protein 5

1

0

High-throughput

0.249

Low

1111560

STIM1
Stromal interaction molecule 1

1

0

High-throughput

0.249

Low

1116216

PTC1
Protein patched homolog 1

1

0

High-throughput

0.249

Low

1125472

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

0

High-throughput

0.249

Low

1136646

HERP1
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein

1

0

High-throughput

0.249

Low

1204860

MKS3
Meckelin

1

0

High-throughput

0.249

Low

1206829

CP135
Centrosomal protein of 135 kDa

1

0

High-throughput

0.249

Low

1206836

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

1206839

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1206840

ATG9A
Autophagy-related protein 9A

1

0

High-throughput

0.249

Low

1206848

TMM17
Transmembrane protein 17

1

0

High-throughput

0.249

Low

1206849

DYR2
Dihydrofolate reductase 2, mitochondrial

1

0

High-throughput

0.249

Low

1206859

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.249

Low

1206860

DHB11
Estradiol 17-beta-dehydrogenase 11

1

0

High-throughput

0.249

Low

1206863

PDZD8
PDZ domain-containing protein 8

1

0

High-throughput

0.249

Low

1206870

AKAP1
A-kinase anchor protein 1, mitochondrial

1

0

High-throughput

0.249

Low

1206875

S2546
Mitochondrial outer membrane protein SLC25A46

1

0

High-throughput

0.249

Low

1206882

TM237
Transmembrane protein 237

1

0

High-throughput

0.249

Low

1206883

PANX1
Pannexin-1

1

0

High-throughput

0.249

Low

1206886

SEC62
Translocation protein SEC62

1

0

High-throughput

0.249

Low

1206894

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

0

High-throughput

0.249

Low

1206897

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1206900

TMT1A
Thiol S-methyltransferase TMT1A

1

0

High-throughput

0.249

Low

1206902

PXMP2
Peroxisomal membrane protein 2

1

0

High-throughput

0.249

Low

1206903

ARHG4
Rho guanine nucleotide exchange factor 4

1

0

High-throughput

0.249

Low

1206904

ST7
Suppressor of tumorigenicity 7 protein

1

0

High-throughput

0.249

Low

1206911

ELOV5
Very long chain fatty acid elongase 5

1

0

High-throughput

0.249

Low

1206914

TM216
Transmembrane protein 216

1

0

High-throughput

0.249

Low

1206915

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

0

High-throughput

0.249

Low

1155060

UT2
Urea transporter 2

1

0

High-throughput

0.232

Low

1206837

ZNT10
Calcium/manganese antiporter SLC30A10

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025