Protein: RPAP1
RNA polymerase II-associated protein 1

Gene: RPAP1
Organism: Homo sapiens
Interactions: 99
UniProt ID: Q9BWH6

Gene Ontology (top 5):
GO:0000428 - DNA-directed RNA polymerase complex
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0006366 - transcription by RNA polymerase II
GO:0016779 - nucleotidyltransferase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

912224

RPB11
DNA-directed RNA polymerase II subunit RPB11-a

5

3

Small-scale

0.712

High

983698

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

4

1

Small-scale

0.700

High

621734

RPB3
DNA-directed RNA polymerase II subunit RPB3

4

3

Small-scale

0.687

High

723072

RPB2
DNA-directed RNA polymerase II subunit RPB2

3

3

Small-scale

0.658

High

1416235

GPN2
GPN-loop GTPase 2

4

3

Small-scale

0.634

High

180381

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

2

3

High-throughput

0.628

High

1416237

GPN1
GPN-loop GTPase 1

4

3

Small-scale

0.625

High

537827

HSP7C
Heat shock cognate 71 kDa protein

3

0

High-throughput

0.616

High

625597

CSK22
Casein kinase II subunit alpha'

1

1

High-throughput

0.536

High

997990

CSK21
Casein kinase II subunit alpha

1

1

High-throughput

0.536

High

1416228

RPB1B
DNA-directed RNA polymerase II subunit RPB11-b1

1

3

High-throughput

0.536

High

1416240

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.529

High

922283

LIMK1
LIM domain kinase 1

1

0

High-throughput

0.513

High

923530

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

0

High-throughput

0.513

High

1062626

DHX9
ATP-dependent RNA helicase A

1

0

High-throughput

0.513

High

1148030

SF3B3
Splicing factor 3B subunit 3

1

0

High-throughput

0.513

High

1207258

SOLH1
Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1

1

0

High-throughput

0.513

High

1416243

POLK
DNA polymerase kappa

1

0

High-throughput

0.513

High

831362

CCNF
Cyclin-F

1

0

High-throughput

0.493

High

182756

GP182
G-protein coupled receptor 182

1

1

High-throughput

0.489

High

173307

XPO1
Exportin-1

1

2

High-throughput

0.479

High

315973

RECQ4
ATP-dependent DNA helicase Q4

1

1

High-throughput

0.479

High

848436

MAGA6
Melanoma-associated antigen 6

1

1

High-throughput

0.479

High

1089841

ILF3
Interleukin enhancer-binding factor 3

1

1

High-throughput

0.479

High

1396345

ZFR
Zinc finger RNA-binding protein

1

1

High-throughput

0.479

High

1416239

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

3

High-throughput

0.479

High

1416244

MAGD2
Melanoma-associated antigen D2

1

1

High-throughput

0.479

High

976143

RPB7
DNA-directed RNA polymerase II subunit RPB7

1

0

Small-scale

0.460

High

165083

RPC1
DNA-directed RNA polymerase III subunit RPC1

1

0

High-throughput

0.458

High

193144

DDX3Y
ATP-dependent RNA helicase DDX3Y

1

0

High-throughput

0.458

High

485378

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

0

High-throughput

0.458

High

856898

BAG6
Large proline-rich protein BAG6

1

0

High-throughput

0.458

High

913576

KIF11
Kinesin-like protein KIF11

1

0

High-throughput

0.458

High

952019

PP4C
Serine/threonine-protein phosphatase 4 catalytic subunit

1

0

High-throughput

0.458

High

995241

CSK2B
Casein kinase II subunit beta

1

0

High-throughput

0.458

High

1041849

CENPC
Centromere protein C

1

0

High-throughput

0.458

High

1052852

DUSP2
Dual specificity protein phosphatase 2

1

0

High-throughput

0.458

High

1100327

TIF1B
Transcription intermediary factor 1-beta

1

0

High-throughput

0.458

High

1104477

ILK
Scaffold protein ILK

1

0

High-throughput

0.458

High

1114189

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1127759

HLTF
Helicase-like transcription factor

1

0

High-throughput

0.458

High

1134705

NUMA1
Nuclear mitotic apparatus protein 1

1

0

High-throughput

0.458

High

1138591

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

1152614

ELAV1
ELAV-like protein 1

1

0

High-throughput

0.458

High

1271835

MEPCE
7SK snRNA methylphosphate capping enzyme

1

0

High-throughput

0.458

High

1272257

MCM10
Protein MCM10 homolog

1

0

High-throughput

0.458

High

1276735

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1281604

SLN11
Schlafen family member 11

1

0

High-throughput

0.458

High

1401926

ERBIN
Erbin

1

0

High-throughput

0.458

High

1416233

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1416241

IF2B1
Insulin-like growth factor 2 mRNA-binding protein 1

1

0

High-throughput

0.458

High

1416245

PHF8
Histone lysine demethylase PHF8

1

0

High-throughput

0.458

High

516863

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

1

3

High-throughput

0.445

High

302942

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

1

High-throughput

0.437

High

1397397

CI072
Guanine nucleotide exchange factor C9orf72

1

0

Small-scale

0.426

High

1232011

GL1AD
DNA-directed RNA polymerase II subunit GRINL1A, isoforms 4/5

4

0

High-throughput

0.353

High

506025

GRL1A
DNA-directed RNA polymerase II subunit GRINL1A

4

0

High-throughput

0.339

High

1241238

CA094
Uncharacterized protein C1orf94

2

0

High-throughput

0.328

High

1416238

POTE1
Protection of telomeres protein 1

1

0

High-throughput

0.299

High

296823

ST1C4
Sulfotransferase 1C4

1

0

High-throughput

0.279

Low

347294

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.279

Low

690052

CRBB3
Beta-crystallin B3

1

0

High-throughput

0.279

Low

1160957

PDK4
[Pyruvate dehydrogenase

1

0

High-throughput

0.279

Low

1163938

UPP1
Uridine phosphorylase 1

1

0

High-throughput

0.279

Low

1177078

INF2
Inverted formin-2

1

0

High-throughput

0.279

Low

1370662

M4K1
Mitogen-activated protein kinase kinase kinase kinase 1

1

0

High-throughput

0.279

Low

1381272

FBXW5
F-box/WD repeat-containing protein 5

1

0

High-throughput

0.279

Low

1383841

EFMT3
EEF1A lysine methyltransferase 3

1

0

High-throughput

0.279

Low

1394837

LOXL4
Lysyl oxidase homolog 4

1

0

High-throughput

0.279

Low

1416234

DOCK5
Dedicator of cytokinesis protein 5

1

0

High-throughput

0.279

Low

124475

HAX1
HCLS1-associated protein X-1

1

0

High-throughput

0.249

Low

294281

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

303626

SRP72
Signal recognition particle subunit SRP72

1

0

High-throughput

0.249

Low

412549

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

532919

CH60
60 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.249

Low

821547

TCPZ
T-complex protein 1 subunit zeta

1

0

High-throughput

0.249

Low

984260

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

0

High-throughput

0.249

Low

1178357

CL16A
Protein CLEC16A

1

0

High-throughput

0.249

Low

1220766

RN123
E3 ubiquitin-protein ligase RNF123

1

0

High-throughput

0.249

Low

1249185

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

1255367

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1360815

ASB11
Ankyrin repeat and SOCS box protein 11

1

0

High-throughput

0.249

Low

1368944

GOGA1
Golgin subfamily A member 1

1

0

High-throughput

0.249

Low

1399495

IPO9
Importin-9

1

0

High-throughput

0.249

Low

1405840

DNJC7
DnaJ homolog subfamily C member 7

1

0

High-throughput

0.249

Low

1415072

LRC61
Leucine-rich repeat-containing protein 61

1

0

High-throughput

0.249

Low

1416229

CCDC8
Coiled-coil domain-containing protein 8

1

0

High-throughput

0.249

Low

1416230

APC1
Anaphase-promoting complex subunit 1

1

0

High-throughput

0.249

Low

1416231

DNJC5
DnaJ homolog subfamily C member 5

1

0

High-throughput

0.249

Low

1416232

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1416236

SYTL2
Synaptotagmin-like protein 2

1

0

High-throughput

0.249

Low

1416242

RHG23
Rho GTPase-activating protein 23

1

0

High-throughput

0.249

Low

505974

MYZAP
Myocardial zonula adherens protein

1

0

High-throughput

0.232

Low

638513

FPR1
fMet-Leu-Phe receptor

1

0

High-throughput

0.232

Low

877717

SL9A3
Sodium/hydrogen exchanger 3

1

0

High-throughput

0.232

Low

1063072

S20A2
Sodium-dependent phosphate transporter 2

1

0

High-throughput

0.232

Low

1185869

NSN5B
Putative NOL1/NOP2/Sun domain family member 5B

1

0

High-throughput

0.232

Low

1395654

S35E1
Solute carrier family 35 member E1

1

0

High-throughput

0.232

Low

1401543

S26A8
Testis anion transporter 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025