Protein: UTP16
U3 small nucleolar RNA-associated protein 16 (U3 snoRNA-associated protein 16) (Bud site selection protein 21) (U three protein 16)

Gene: UTP16, BUD21
Organism: Saccharomyces cerevisiae S288C
Interactions: 108
UniProt ID: Q08492

Gene Ontology (top 5):
GO:0000447 - endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000462 - maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 - endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0005730 - nucleolus
GO:0030490 - maturation of SSU-rRNA

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

678479

PWP2
Periodic tryptophan protein 2

5

1

Small-scale

0.712

High

1046070

DHR1
Probable ATP-dependent RNA helicase DHR1

6

0

Small-scale

0.699

High

1064334

NOP56
Nucleolar protein 56

4

1

High-throughput

0.697

High

1056492

UTP4
U3 small nucleolar RNA-associated protein 4

4

1

High-throughput

0.694

High

1055442

RRP9
Ribosomal RNA-processing protein 9

5

0

High-throughput

0.686

High

798340

ENP1
Essential nuclear protein 1

5

0

High-throughput

0.684

High

1064336

NOP58
Nucleolar protein 58

4

1

Small-scale

0.683

High

865188

MPP10
U3 small nucleolar RNA-associated protein MPP10

4

0

Small-scale

0.670

High

1039870

UTP17
NET1-associated nuclear protein 1

3

3

High-throughput

0.667

High

1053126

UTP13
U3 small nucleolar RNA-associated protein 13

3

2

High-throughput

0.667

High

844648

UTP10
U3 small nucleolar RNA-associated protein 10

4

0

High-throughput

0.664

High

924652

NAT10
RNA cytidine acetyltransferase

4

0

High-throughput

0.664

High

1055508

NOC4
Nucleolar complex protein 4

4

0

Small-scale

0.648

High

747059

IMP3
U3 small nucleolar ribonucleoprotein protein IMP3

3

0

High-throughput

0.638

High

763644

UTP20
U3 small nucleolar RNA-associated protein 20

3

0

High-throughput

0.638

High

817650

UTP7
U3 small nucleolar RNA-associated protein 7

3

0

High-throughput

0.638

High

918845

UTP22
U3 small nucleolar RNA-associated protein 22

3

0

High-throughput

0.638

High

919189

UTP8
U3 small nucleolar RNA-associated protein 8

3

0

High-throughput

0.638

High

1046270

UTP15
U3 small nucleolar RNA-associated protein 15

3

0

High-throughput

0.638

High

1050195

RRP5
rRNA biogenesis protein RRP5

3

0

High-throughput

0.638

High

1064326

BMS1
Ribosome biogenesis protein BMS1

3

0

High-throughput

0.638

High

1064338

RRP12
Ribosomal RNA-processing protein 12

3

0

High-throughput

0.638

High

677597

KRR1
KRR1 small subunit processome component

3

0

High-throughput

0.628

High

823405

UTP18
U3 small nucleolar RNA-associated protein 18

2

0

High-throughput

0.585

High

826224

FAF1
Protein FAF1

2

0

Small-scale

0.585

High

1064341

NOP14
Nucleolar complex protein 14

2

0

High-throughput

0.585

High

1053529

UTP21
U3 small nucleolar RNA-associated protein 21

2

2

Small-scale

0.584

High

782474

RPF2
Ribosome biogenesis protein RPF2

2

0

High-throughput

0.576

High

1064330

RL7B
Large ribosomal subunit protein uL30B

2

0

High-throughput

0.576

High

513260

RS8A
Small ribosomal subunit protein eS8A

2

0

High-throughput

0.559

High

923996

CSL4
Exosome complex component CSL4

2

0

High-throughput

0.559

High

1046815

UTP14
U3 small nucleolar RNA-associated protein 14

2

0

High-throughput

0.559

High

1064329

RRP6
Exosome complex exonuclease RRP6

2

0

High-throughput

0.559

High

743304

PP12
Serine/threonine-protein phosphatase PP1-2

1

0

High-throughput

0.513

High

525389

HSP71
Heat shock protein SSA1

2

1

High-throughput

0.504

High

742562

HSP7F
Heat shock protein homolog SSE1

2

2

High-throughput

0.504

High

863148

RRP41
Exosome complex component SKI6

1

2

High-throughput

0.479

High

918907

RRP46
Exosome complex component RRP46

1

2

High-throughput

0.479

High

1045120

UTP5
U3 small nucleolar RNA-associated protein 5

1

1

High-throughput

0.479

High

1051721

RRP45
Exosome complex component RRP45

1

2

High-throughput

0.479

High

1064331

UTP12
U3 small nucleolar RNA-associated protein 12

1

2

High-throughput

0.479

High

1064332

RRP42
Exosome complex component RRP42

1

2

High-throughput

0.479

High

585398

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

0

High-throughput

0.458

High

672973

RRP43
Exosome complex component RRP43

1

0

High-throughput

0.458

High

673246

RRP7
Ribosomal RNA-processing protein 7

1

0

High-throughput

0.458

High

754350

DCA13
Protein SOF1

1

0

High-throughput

0.458

High

758422

UTP11
U3 small nucleolar RNA-associated protein 11

1

0

High-throughput

0.458

High

782116

RL1D1
Ribosome biogenesis protein UTP30

1

0

High-throughput

0.458

High

804762

RRP4
Exosome complex component RRP4

1

0

High-throughput

0.458

High

804970

LRP1
Exosome complex protein LRP1

1

0

High-throughput

0.458

High

806592

UTP9
U3 small nucleolar RNA-associated protein 9

1

0

High-throughput

0.458

High

808323

RRP8
25S rRNA

1

0

High-throughput

0.458

High

818355

LCP5
U3 small nucleolar ribonucleoprotein protein LCP5

1

0

High-throughput

0.458

High

825094

RRT14
Regulator of rDNA transcription protein 14

1

0

High-throughput

0.458

High

825572

UTP25
U3 small nucleolar RNA-associated protein 25

1

0

High-throughput

0.458

High

852620

ROK1
ATP-dependent RNA helicase ROK1

1

0

High-throughput

0.458

High

864539

MTR4
ATP-dependent RNA helicase DOB1

1

0

High-throughput

0.458

High

871071

NOL10
Ribosome biogenesis protein ENP2

1

0

High-throughput

0.458

High

871137

MTR3
Exosome complex component MTR3

1

0

High-throughput

0.458

High

919561

SDA1
Protein SDA1

1

0

High-throughput

0.458

High

923265

ESF2
Pre-rRNA-processing protein ESF2

1

0

High-throughput

0.458

High

925212

IMP4
U3 small nucleolar ribonucleoprotein protein IMP4

1

0

High-throughput

0.458

High

1036425

UTP6
U3 small nucleolar RNA-associated protein 6

1

0

High-throughput

0.458

High

1051171

FCF1
rRNA-processing protein FCF1

1

0

High-throughput

0.458

High

1054551

NEP1
Ribosomal RNA small subunit methyltransferase NEP1

1

0

High-throughput

0.458

High

1054903

ESF1
Pre-rRNA-processing protein ESF1

1

0

High-throughput

0.458

High

1056321

BFR2
Protein BFR2

1

0

High-throughput

0.458

High

1061640

RCL1
rRNA processing protein RCL1

1

0

High-throughput

0.458

High

1061952

RRP44
Exosome complex exonuclease DIS3

1

0

High-throughput

0.458

High

1062915

RRP40
Exosome complex component RRP40

1

0

High-throughput

0.458

High

1064327

FCF2
rRNA-processing protein FCF2

1

0

High-throughput

0.458

High

1064328

SAS10
Something about silencing protein 10

1

0

High-throughput

0.458

High

1064333

DBP10
ATP-dependent RNA helicase DBP10

1

0

High-throughput

0.458

High

1064335

RRP36
rRNA biogenesis protein RRP36

1

0

High-throughput

0.458

High

1064339

EFG1P
rRNA-processing protein EFG1

1

0

High-throughput

0.458

High

1064342

PNO1
Pre-rRNA-processing protein PNO1

1

0

High-throughput

0.458

High

656657

KC11
Casein kinase I homolog 1

1

1

High-throughput

0.457

High

656897

KC12
Casein kinase I homolog 2

1

1

High-throughput

0.457

High

503280

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.437

High

708398

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

708796

TF3B
Transcription factor IIIB 70 kDa subunit

1

1

High-throughput

0.437

High

1064340

RS22B
Small ribosomal subunit protein uS8B

1

1

High-throughput

0.437

High

527879

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.407

High

779588

LHS1
Heat shock protein 70 homolog LHS1

1

2

High-throughput

0.407

High

885104

RL4B
Large ribosomal subunit protein uL4B

2

0

High-throughput

0.313

High

546561

SSB1
Ribosome-associated molecular chaperone SSB1

2

0

High-throughput

0.288

High

1030595

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

0

High-throughput

0.279

Low

627873

PRP4
U4/U6 small nuclear ribonucleoprotein PRP4

1

0

High-throughput

0.269

Low

1056380

IPK1
Inositol-pentakisphosphate 2-kinase

1

0

High-throughput

0.265

Low

1064337

TMA17
Translation machinery-associated protein 17

1

0

High-throughput

0.265

Low

651995

ESS1
Peptidyl-prolyl cis-trans isomerase ESS1

1

0

High-throughput

0.261

Low

692445

KCC1
Calcium/calmodulin-dependent protein kinase I

1

0

High-throughput

0.261

Low

748912

SWE1
Mitosis inhibitor protein kinase SWE1

1

0

High-throughput

0.261

Low

917200

ATG1
Serine/threonine-protein kinase ATG1

1

0

High-throughput

0.261

Low

1043543

SKY1
Serine/threonine-protein kinase SKY1

1

0

High-throughput

0.261

Low

448341

PDE2
3',5'-cyclic-nucleotide phosphodiesterase 2

1

0

High-throughput

0.249

Low

636692

PSA1
Proteasome subunit alpha type-1

1

0

High-throughput

0.249

Low

811642

YCFI
Metal resistance protein YCF1

1

0

High-throughput

0.249

Low

812725

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

824804

MLP2
Protein MLP2

1

0

High-throughput

0.249

Low

826899

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

932242

ORC1
Origin recognition complex subunit 1

1

0

High-throughput

0.249

Low

1051619

HRQ1
ATP-dependent helicase HRQ1

1

0

Small-scale

0.249

Low

1053994

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

1054862

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.249

Low

1064271

SGO1
Shugoshin

1

0

High-throughput

0.249

Low

503444

RL11A
Large ribosomal subunit protein uL5A

1

0

High-throughput

0.232

Low

804520

SSZ1
Ribosome-associated complex subunit SSZ1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025