Protein: SCC4
MAU2 chromatid cohesion factor homolog (MAU-2) (Cohesin loading complex subunit SCC4 homolog)

Gene: SCC4, MAU2
Organism: Homo sapiens
Interactions: 135
UniProt ID: Q9Y6X3

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0007059 - chromosome segregation
GO:0007064 - mitotic sister chromatid cohesion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1235702

NIPBL
Nipped-B-like protein

6

1

Small-scale

0.736

High

853446

CBX5
Chromobox protein homolog 5

2

3

Small-scale

0.628

High

1014243

CBX1
Chromobox protein homolog 1

2

3

High-throughput

0.628

High

911446

IMA5
Importin subunit alpha-5

3

0

High-throughput

0.622

High

1258436

MOB3C
MOB kinase activator 3C

2

0

High-throughput

0.595

High

1491866

SCC4
MAU2 chromatid cohesion factor homolog

1

0

High-throughput

0.586

High

1130239

SMC1A
Structural maintenance of chromosomes protein 1A

2

0

High-throughput

0.585

High

176103

KDM6B
Lysine-specific demethylase 6B

2

0

Small-scale

0.559

High

260666

BRD4
Bromodomain-containing protein 4

2

0

High-throughput

0.559

High

542303

TOP1
DNA topoisomerase 1

1

1

High-throughput

0.536

High

857610

NOTC1
Neurogenic locus notch homolog protein 1

1

0

High-throughput

0.513

High

943880

CF298
Cilia- and flagella-associated protein 298

1

0

High-throughput

0.513

High

1065520

SSRP1
FACT complex subunit SSRP1

1

0

High-throughput

0.513

High

1163323

H2B2E
Histone H2B type 2-E

1

0

High-throughput

0.513

High

1253890

SRCAP
Helicase SRCAP

1

0

High-throughput

0.513

High

1405931

DNJC7
DnaJ homolog subfamily C member 7

1

0

High-throughput

0.513

High

1461610

AT7L1
Ataxin-7-like protein 1

1

1

High-throughput

0.489

High

1026307

CLH1
Clathrin heavy chain 1

1

0

High-throughput

0.480

High

143363

NFIB
Nuclear factor 1 B-type

1

3

High-throughput

0.479

High

212358

SNUT1
U4/U6.U5 tri-snRNP-associated protein 1

1

2

High-throughput

0.479

High

289744

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

1

2

High-throughput

0.479

High

462735

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

1

High-throughput

0.479

High

474417

NFIC
Nuclear factor 1 C-type

1

3

High-throughput

0.479

High

608809

DDX5
Probable ATP-dependent RNA helicase DDX5

1

1

High-throughput

0.479

High

651048

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

1

High-throughput

0.479

High

655392

SFPQ
Splicing factor, proline- and glutamine-rich

1

1

High-throughput

0.479

High

713490

SPB3
Serpin B3

1

1

High-throughput

0.479

High

729515

HNRH1
Heterogeneous nuclear ribonucleoprotein H

1

3

High-throughput

0.479

High

846554

MATR3
Matrin-3

1

1

High-throughput

0.479

High

854407

KI67
Proliferation marker protein Ki-67

1

2

High-throughput

0.479

High

909749

ROA3
Heterogeneous nuclear ribonucleoprotein A3

1

1

High-throughput

0.479

High

913108

HNRPF
Heterogeneous nuclear ribonucleoprotein F

1

3

High-throughput

0.479

High

938838

HNRH2
Heterogeneous nuclear ribonucleoprotein H2

1

3

High-throughput

0.479

High

964786

DCAF7
DDB1- and CUL4-associated factor 7

1

1

High-throughput

0.479

High

965961

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

3

High-throughput

0.479

High

1027889

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

1

High-throughput

0.479

High

1040769

ENL
Protein ENL

1

1

High-throughput

0.479

High

1088138

NFIA
Nuclear factor 1 A-type

1

3

High-throughput

0.479

High

1097656

CBX3
Chromobox protein homolog 3

1

3

High-throughput

0.479

High

1111405

SNW1
SNW domain-containing protein 1

1

1

High-throughput

0.479

High

1133770

NFIX
Nuclear factor 1 X-type

1

3

High-throughput

0.479

High

1144519

NONO
Non-POU domain-containing octamer-binding protein

1

1

High-throughput

0.479

High

1146900

PCBP1
Poly(rC)-binding protein 1

1

3

High-throughput

0.479

High

1217239

RIF1
Telomere-associated protein RIF1

1

1

High-throughput

0.479

High

1259084

MD13L
Mediator of RNA polymerase II transcription subunit 13-like

1

1

High-throughput

0.479

High

1270360

SPT6H
Transcription elongation factor SPT6

1

1

High-throughput

0.479

High

1369436

DDX17
Probable ATP-dependent RNA helicase DDX17

1

1

High-throughput

0.479

High

1370883

FUBP2
Far upstream element-binding protein 2

1

3

High-throughput

0.479

High

1393990

FUBP3
Far upstream element-binding protein 3

1

3

High-throughput

0.479

High

1410421

MEP50
Methylosome protein WDR77

1

1

High-throughput

0.479

High

1453452

BICRA
BRD4-interacting chromatin-remodeling complex-associated protein

1

1

High-throughput

0.479

High

1460089

MED13
Mediator of RNA polymerase II transcription subunit 13

1

1

High-throughput

0.479

High

1462091

PRP19
Pre-mRNA-processing factor 19

1

1

High-throughput

0.479

High

1490467

RUVB2
RuvB-like 2

1

1

High-throughput

0.479

High

1490531

RUVB1
RuvB-like 1

1

1

High-throughput

0.479

High

1490964

TR150
Thyroid hormone receptor-associated protein 3

1

2

High-throughput

0.479

High

162750

ANM5
Protein arginine N-methyltransferase 5

1

0

High-throughput

0.458

High

180448

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

0

High-throughput

0.458

High

229108

AKAP8
A-kinase anchor protein 8

1

0

High-throughput

0.458

High

243459

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

280888

PR40A
Pre-mRNA-processing factor 40 homolog A

1

0

High-throughput

0.458

High

286127

SF3B1
Splicing factor 3B subunit 1

1

0

High-throughput

0.458

High

340955

NFAC1
Nuclear factor of activated T-cells, cytoplasmic 1

1

0

High-throughput

0.458

High

355330

ACL6A
Actin-like protein 6A

1

0

High-throughput

0.458

High

386420

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.458

High

409150

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

0

High-throughput

0.458

High

418769

GNAI2
Guanine nucleotide-binding protein G(i) subunit alpha-2

1

0

High-throughput

0.458

High

429084

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.458

High

456903

ANXA2
Annexin A2

1

0

High-throughput

0.458

High

468968

HS90B
Heat shock protein HSP 90-beta

1

0

High-throughput

0.458

High

476889

RSSA
Small ribosomal subunit protein uS2

1

0

High-throughput

0.458

High

508931

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

High-throughput

0.458

High

538197

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

605098

JUND
Transcription factor JunD

1

0

High-throughput

0.458

High

620681

NUCL
Nucleolin

1

0

High-throughput

0.458

High

637818

FLNA
Filamin-A

1

0

High-throughput

0.458

High

687551

PTBP1
Polypyrimidine tract-binding protein 1

1

0

High-throughput

0.458

High

769930

RFC2
Replication factor C subunit 2

1

0

High-throughput

0.458

High

799623

BRCA1
Breast cancer type 1 susceptibility protein

1

0

High-throughput

0.458

High

890626

RBP2
E3 SUMO-protein ligase RanBP2

1

0

High-throughput

0.458

High

910750

HNRPM
Heterogeneous nuclear ribonucleoprotein M

1

0

High-throughput

0.458

High

937381

DSRAD
Double-stranded RNA-specific adenosine deaminase

1

0

High-throughput

0.458

High

965383

WDR5
WD repeat-containing protein 5

1

0

High-throughput

0.458

High

980638

H4
Histone H4

1

0

High-throughput

0.458

High

985979

RL11
Large ribosomal subunit protein uL5

1

0

High-throughput

0.458

High

996411

EF1A1
Elongation factor 1-alpha 1

1

0

High-throughput

0.458

High

996907

TBA1B
Tubulin alpha-1B chain

1

0

High-throughput

0.458

High

1008425

PRKDC
DNA-dependent protein kinase catalytic subunit

1

0

High-throughput

0.458

High

1023203

RBM10
RNA-binding protein 10

1

0

High-throughput

0.458

High

1030516

FABP5
Fatty acid-binding protein 5

1

0

High-throughput

0.458

High

1039594

TOP2B
DNA topoisomerase 2-beta

1

0

High-throughput

0.458

High

1089087

TP53B
TP53-binding protein 1

1

0

High-throughput

0.458

High

1108778

TBB3
Tubulin beta-3 chain

1

0

High-throughput

0.458

High

1119937

CKAP5
Cytoskeleton-associated protein 5

1

0

High-throughput

0.458

High

1130898

RRP5
Protein RRP5 homolog

1

0

High-throughput

0.458

High

1144338

STK38
Serine/threonine-protein kinase 38

1

0

High-throughput

0.458

High

1148100

SF3B3
Splicing factor 3B subunit 3

1

0

High-throughput

0.458

High

1150858

SF01
Splicing factor 1

1

0

High-throughput

0.458

High

1236148

TET2
Methylcytosine dioxygenase TET2

1

0

High-throughput

0.458

High

1275993

SETX
Probable helicase senataxin

1

0

High-throughput

0.458

High

1279260

WAPL
Wings apart-like protein homolog

1

0

High-throughput

0.458

High

1310150

MGAP
MAX gene-associated protein

1

0

High-throughput

0.458

High

1325420

STAG2
Cohesin subunit SA-2

1

0

High-throughput

0.458

High

1359967

PRP31
U4/U6 small nuclear ribonucleoprotein Prp31

1

0

High-throughput

0.458

High

1360105

PALLD
Palladin

1

0

High-throughput

0.458

High

1368231

HDAC2
Histone deacetylase 2

1

0

High-throughput

0.458

High

1372224

MED12
Mediator of RNA polymerase II transcription subunit 12

1

0

High-throughput

0.458

High

1392092

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

1

0

High-throughput

0.458

High

1399809

RBM14
RNA-binding protein 14

1

0

High-throughput

0.458

High

1416415

CDK19
Cyclin-dependent kinase 19

1

0

High-throughput

0.458

High

1417843

PDIP3
Polymerase delta-interacting protein 3

1

0

High-throughput

0.458

High

1430054

INT2
Integrator complex subunit 2

1

0

High-throughput

0.458

High

1430922

APC1
Anaphase-promoting complex subunit 1

1

0

High-throughput

0.458

High

1449725

MDN1
Midasin

1

0

High-throughput

0.458

High

1461539

ZN608
Zinc finger protein 608

1

0

High-throughput

0.458

High

1461639

PRR12
Proline-rich protein 12

1

0

High-throughput

0.458

High

1491322

PKP3
Plakophilin-3

1

0

High-throughput

0.458

High

158049

CTRO
Citron Rho-interacting kinase

1

1

High-throughput

0.437

High

874894

SPB4
Serpin B4

1

1

High-throughput

0.437

High

1454176

CAMP3
Calmodulin-regulated spectrin-associated protein 3

1

1

High-throughput

0.437

High

1329746

ARFG1
ADP-ribosylation factor GTPase-activating protein 1

2

0

High-throughput

0.328

High

441460

CHLE
Cholinesterase

1

0

High-throughput

0.279

Low

477352

NMB
Neuromedin-B [Cleaved into: Neuromedin-B-32; Neuromedin-B]

1

0

High-throughput

0.279

Low

1216428

FAXC
Failed axon connections homolog

1

0

High-throughput

0.279

Low

1491413

GPSM3
G-protein-signaling modulator 3

1

0

High-throughput

0.279

Low

417882

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.249

Low

945334

NU107
Nuclear pore complex protein Nup107

1

0

High-throughput

0.249

Low

1062326

TGM3
Protein-glutamine gamma-glutamyltransferase E

1

0

High-throughput

0.249

Low

1340395

CEP70
Centrosomal protein of 70 kDa

1

0

High-throughput

0.249

Low

1358609

POF1B
Protein POF1B

1

0

High-throughput

0.249

Low

1439166

ZDBF2
DBF4-type zinc finger-containing protein 2

1

0

High-throughput

0.249

Low

1454330

SLAI2
SLAIN motif-containing protein 2

1

0

High-throughput

0.249

Low

1490684

PLAK2
PALM2-AKAP2 fusion protein

1

0

High-throughput

0.249

Low

1491763

SNX9
Sorting nexin-9

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025