Protein: NNTM
NAD(P) transhydrogenase, mitochondrial (EC 7.1.1.1) (Nicotinamide nucleotide transhydrogenase) (Pyridine nucleotide transhydrogenase)

Gene: NNTM, NNT
Organism: Homo sapiens
Interactions: 125
UniProt ID: Q13423

Gene Ontology (top 5):
GO:0003957 - NAD(P)+ transhydrogenase (Si-specific) activity
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0006099 - tricarboxylic acid cycle
GO:0006740 - NADPH regeneration

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

275285

NDUS7
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial

2

0

High-throughput

0.602

High

878022

AGRE5
Adhesion G protein-coupled receptor E5

2

0

High-throughput

0.602

High

279753

CISY
Citrate synthase, mitochondrial

2

1

High-throughput

0.584

High

418104

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

2

0

High-throughput

0.559

High

470291

NEP
Neprilysin

1

0

Small-scale

0.513

High

772779

MYH9
Myosin-9

1

0

High-throughput

0.513

High

869154

UCRI
Cytochrome b-c1 complex subunit Rieske, mitochondrial

1

0

High-throughput

0.513

High

1104734

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

0

High-throughput

0.513

High

1104741

ATLA2
Atlastin-2

1

0

High-throughput

0.513

High

281946

MPPB
Mitochondrial-processing peptidase subunit beta

1

1

High-throughput

0.479

High

287288

RF1M
Peptide chain release factor 1, mitochondrial

1

1

High-throughput

0.479

High

292123

S2512
Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial

1

1

High-throughput

0.479

High

415541

HSPB1
Heat shock protein beta-1

1

1

Small-scale

0.479

High

828768

MDHM
Malate dehydrogenase, mitochondrial

1

1

High-throughput

0.479

High

856259

IF2M
Translation initiation factor IF-2, mitochondrial

1

1

High-throughput

0.479

High

1083606

MPPA
Mitochondrial-processing peptidase subunit alpha

1

1

High-throughput

0.479

High

1104716

DCTN1
Dynactin subunit 1

1

1

High-throughput

0.479

High

1104733

FAKD5
FAST kinase domain-containing protein 5, mitochondrial

1

1

High-throughput

0.479

High

1104735

CNTRL
Centriolin

1

1

High-throughput

0.479

High

1104740

MCU
Calcium uniporter protein, mitochondrial

1

1

High-throughput

0.479

High

1104746

FAKD4
FAST kinase domain-containing protein 4

1

1

High-throughput

0.479

High

1104747

MCUR1
Mitochondrial calcium uniporter regulator 1

1

1

High-throughput

0.479

High

1104760

CC90B
Coiled-coil domain-containing protein 90B, mitochondrial

1

1

High-throughput

0.479

High

1104770

MCUB
Calcium uniporter regulatory subunit MCUb, mitochondrial

1

1

High-throughput

0.479

High

1104774

RF1ML
Peptide chain release factor 1-like, mitochondrial

1

1

High-throughput

0.479

High

1104717

MVP
Major vault protein

1

0

High-throughput

0.460

High

61495

VWA8
von Willebrand factor A domain-containing protein 8

1

0

High-throughput

0.458

High

133743

PDE2A
cGMP-dependent 3',5'-cyclic phosphodiesterase

1

0

High-throughput

0.458

High

137713

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

0

High-throughput

0.458

High

184289

NPHP1
Nephrocystin-1

1

0

High-throughput

0.458

High

275016

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

0

High-throughput

0.458

High

289991

OFD1
Centriole and centriolar satellite protein OFD1

1

0

High-throughput

0.458

High

345764

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

350863

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

1

0

High-throughput

0.458

High

411874

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.458

High

413770

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

471012

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

0

High-throughput

0.458

High

485117

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

0

High-throughput

0.458

High

519112

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.458

High

532565

CH60
60 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.458

High

568409

ETFA
Electron transfer flavoprotein subunit alpha, mitochondrial

1

0

High-throughput

0.458

High

774332

BASI
Basigin

1

0

High-throughput

0.458

High

786087

LONM
Lon protease homolog, mitochondrial

1

0

High-throughput

0.458

High

841719

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

0

High-throughput

0.458

High

851885

EFTS
Elongation factor Ts, mitochondrial

1

0

High-throughput

0.458

High

882657

EFTU
Elongation factor Tu, mitochondrial

1

0

High-throughput

0.458

High

1048495

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1058003

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1090389

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

0

High-throughput

0.458

High

1104712

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

1104714

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

0

High-throughput

0.458

High

1104715

ICT1
Large ribosomal subunit protein mL62

1

0

High-throughput

0.458

High

1104719

SURF1
Surfeit locus protein 1

1

0

High-throughput

0.458

High

1104720

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

0

High-throughput

0.458

High

1104722

SYAM
Alanine--tRNA ligase, mitochondrial

1

0

High-throughput

0.458

High

1104732

COX15
Heme A synthase COX15

1

0

High-throughput

0.458

High

1104737

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.458

High

1104738

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.458

High

1104748

RUSD4
Pseudouridylate synthase RPUSD4, mitochondrial

1

0

High-throughput

0.458

High

1104750

RRFM
Ribosome-recycling factor, mitochondrial

1

0

High-throughput

0.458

High

1104751

EFGM
Elongation factor G, mitochondrial

1

0

High-throughput

0.458

High

1104752

ECSIT
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

1

0

High-throughput

0.458

High

1104753

CQ080
Mitochondrial nucleoid-associated protein 1

1

0

High-throughput

0.458

High

1104754

TMM70
Transmembrane protein 70, mitochondrial

1

0

High-throughput

0.458

High

1104755

HINT2
Adenosine 5'-monophosphoramidase HINT2

1

0

High-throughput

0.458

High

1104758

RT26
Small ribosomal subunit protein mS26

1

0

High-throughput

0.458

High

1104759

NMES1
Normal mucosa of esophagus-specific gene 1 protein

1

0

High-throughput

0.458

High

1104762

IF3M
Translation initiation factor IF-3, mitochondrial

1

0

High-throughput

0.458

High

1104763

IPYR2
Inorganic pyrophosphatase 2, mitochondrial

1

0

High-throughput

0.458

High

1104764

MTG2
Mitochondrial ribosome-associated GTPase 2

1

0

High-throughput

0.458

High

1104766

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

0

High-throughput

0.458

High

1104772

MRES1
Mitochondrial transcription rescue factor 1

1

0

High-throughput

0.458

High

1104777

RM11
Large ribosomal subunit protein uL11m

1

0

High-throughput

0.458

High

142982

NFIB
Nuclear factor 1 B-type

1

1

High-throughput

0.437

High

323359

TRI37
E3 ubiquitin-protein ligase TRIM37

1

1

High-throughput

0.437

High

473967

NFIC
Nuclear factor 1 C-type

1

1

High-throughput

0.437

High

1104725

FTM
Protein fantom

1

1

High-throughput

0.437

High

1104739

PAPD5
Terminal nucleotidyltransferase 4B

1

1

High-throughput

0.437

High

1104744

FBF1
Fas-binding factor 1

1

1

High-throughput

0.437

High

1104765

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.437

High

248868

GSDME
Gasdermin-E

1

0

High-throughput

0.426

High

529743

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

598552

UD2B7
UDP-glucuronosyltransferase 2B7

1

0

Small-scale

0.426

High

1104723

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

1104727

MFSD5
Molybdate-anion transporter

1

0

High-throughput

0.426

High

1104729

NPAL3
NIPA-like protein 3

1

0

High-throughput

0.426

High

1104742

ZNT5
Proton-coupled zinc antiporter SLC30A5

1

0

High-throughput

0.426

High

1104756

S12A9
Solute carrier family 12 member 9

1

0

High-throughput

0.426

High

1104769

EVA1B
Protein eva-1 homolog B

1

0

High-throughput

0.426

High

1104778

RT23
Small ribosomal subunit protein mS23

1

0

High-throughput

0.426

High

109147

G4U4J3
Terminal nucleotidyltransferase 4B

1

1

High-throughput

0.407

High

1104776

GAB2
GRB2-associated-binding protein 2

1

1

High-throughput

0.407

High

1104724

SUSD4
Sushi domain-containing protein 4

3

0

High-throughput

0.347

High

1104767

GPC5C
G-protein coupled receptor family C group 5 member C

3

0

High-throughput

0.345

High

662573

GATA3
Trans-acting T-cell-specific transcription factor GATA-3

1

0

High-throughput

0.279

Low

1104743

NEIL3
Endonuclease 8-like 3

1

0

High-throughput

0.279

Low

1104773

SLAI2
SLAIN motif-containing protein 2

1

0

High-throughput

0.279

Low

337875

CLD7
Claudin-7

1

0

High-throughput

0.269

Low

105872

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

164328

NRP1
Neuropilin-1

1

0

High-throughput

0.249

Low

353309

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.249

Low

588617

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

695374

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

768109

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

907412

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

0

High-throughput

0.249

Low

1004523

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.249

Low

1015412

RHOG
Rho-related GTP-binding protein RhoG

1

0

High-throughput

0.249

Low

1104713

CUL4A
Cullin-4A

1

0

High-throughput

0.249

Low

1104718

CUL7
Cullin-7

1

0

High-throughput

0.249

Low

1104721

MIDN
Midnolin

1

0

High-throughput

0.249

Low

1104726

VIR
Protein virilizer homolog

1

0

High-throughput

0.249

Low

1104730

BAKOR
Beclin 1-associated autophagy-related key regulator

1

0

High-throughput

0.249

Low

1104731

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1104736

RHG24
Rho GTPase-activating protein 24

1

0

High-throughput

0.249

Low

1104749

FAF2
FAS-associated factor 2

1

0

High-throughput

0.249

Low

1104757

FACD2
Fanconi anemia group D2 protein

1

0

High-throughput

0.249

Low

1104761

CCDC8
Coiled-coil domain-containing protein 8

1

0

High-throughput

0.249

Low

1104768

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

0

High-throughput

0.249

Low

1104771

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.249

Low

1104775

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.249

Low

50097

S22AN
Solute carrier family 22 member 23

1

0

High-throughput

0.232

Low

466889

ACM4
Muscarinic acetylcholine receptor M4

1

0

High-throughput

0.232

Low

730565

1433S
14-3-3 protein sigma

1

0

High-throughput

0.232

Low

1104728

ARMC6
Armadillo repeat-containing protein 6

1

0

High-throughput

0.232

Low

1104745

LPAR1
Lysophosphatidic acid receptor 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025