Protein: TCF20
Transcription factor 20 (TCF-20) (Nuclear factor SPBP) (Protein AR1) (Stromelysin-1 PDGF-responsive element-binding protein) (SPRE-binding protein)

Gene: TCF20
Organism: Homo sapiens
Interactions: 135
UniProt ID: Q9UGU0

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006357 - regulation of transcription by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

520428

ANDR
Androgen receptor

4

20

Small-scale

0.692

High

1279178

RAI1
Retinoic acid-induced protein 1

1

16

High-throughput

0.691

High

1381880

H2B1A
Histone H2B type 1-A

4

20

High-throughput

0.691

High

373411

MYC
Myc proto-oncogene protein

4

13

High-throughput

0.676

High

404522

GCR
Glucocorticoid receptor

3

20

Small-scale

0.640

High

502165

H2AZ
Histone H2A.Z

2

16

High-throughput

0.628

High

1110153

HDAC1
Histone deacetylase 1

2

13

High-throughput

0.628

High

1163267

H2B2E
Histone H2B type 2-E

2

20

Small-scale

0.619

High

1159039

RBBP7
Histone-binding protein RBBP7

2

16

High-throughput

0.611

High

1005216

RNF4
E3 ubiquitin-protein ligase RNF4

2

1

Small-scale

0.606

High

1364292

TOPB1
DNA topoisomerase 2-binding protein 1

1

14

Small-scale

0.594

High

1049881

1433F
14-3-3 protein eta

3

20

High-throughput

0.593

High

872844

SOX2
Transcription factor SOX-2

2

20

Small-scale

0.584

High

980490

H4
Histone H4

2

9

High-throughput

0.584

High

1339017

NUP43
Nucleoporin Nup43

2

20

High-throughput

0.584

High

1158199

MK14
Mitogen-activated protein kinase 14

1

7

High-throughput

0.541

High

155366

CDKA1
Cyclin-dependent kinase 2-associated protein 1

1

1

High-throughput

0.536

High

166203

AIM2
Interferon-inducible protein AIM2

1

3

High-throughput

0.536

High

317024

MTA2
Metastasis-associated protein MTA2

1

9

High-throughput

0.536

High

542266

TOP1
DNA topoisomerase 1

1

2

High-throughput

0.536

High

572266

TRI27
Zinc finger protein RFP

1

4

High-throughput

0.536

High

601895

HMGA1
High mobility group protein HMG-I/HMG-Y

1

4

High-throughput

0.536

High

625688

CSK22
Casein kinase II subunit alpha'

1

9

High-throughput

0.536

High

703733

MK01
Mitogen-activated protein kinase 1

1

6

High-throughput

0.536

High

1008925

RED1
Double-stranded RNA-specific editase 1

1

6

High-throughput

0.536

High

1066534

RBBP4
Histone-binding protein RBBP4

1

16

High-throughput

0.536

High

1235558

IFIX
Pyrin and HIN domain-containing protein 1

1

3

High-throughput

0.536

High

1287793

NOP9
Nucleolar protein 9

1

2

High-throughput

0.536

High

1295320

P66A
Transcriptional repressor p66-alpha

1

2

High-throughput

0.536

High

1361030

P66B
Transcriptional repressor p66-beta

1

2

High-throughput

0.536

High

1368182

HDAC2
Histone deacetylase 2

1

13

High-throughput

0.536

High

1371759

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

8

High-throughput

0.536

High

1403042

SIN3A
Paired amphipathic helix protein Sin3a

1

1

High-throughput

0.536

High

1431071

NUCKS
Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1

1

2

High-throughput

0.536

High

1445903

HM20A
High mobility group protein 20A

1

20

High-throughput

0.536

High

571002

MIF
Macrophage migration inhibitory factor

1

0

High-throughput

0.513

High

1371362

TF3B
Transcription factor IIIB 90 kDa subunit

1

0

High-throughput

0.513

High

430472

JUN
Transcription factor Jun

1

10

Small-scale

0.501

High

1162919

H2A2C
Histone H2A type 2-C

1

13

Small-scale

0.501

High

967593

RS7
Small ribosomal subunit protein eS7

1

0

High-throughput

0.493

High

921825

COPB
Coatomer subunit beta

1

1

High-throughput

0.489

High

1434487

ACTL8
Actin-like protein 8

1

3

High-throughput

0.489

High

1459653

S39AA
Zinc transporter ZIP10

1

1

High-throughput

0.489

High

1154018

SMAD1
Mothers against decapentaplegic homolog 1

1

4

High-throughput

0.481

High

129518

MEN1
Menin

1

5

High-throughput

0.479

High

130647

SPT5H
Transcription elongation factor SPT5

1

13

High-throughput

0.479

High

143309

NFIB
Nuclear factor 1 B-type

1

20

High-throughput

0.479

High

157953

CTRO
Citron Rho-interacting kinase

1

5

High-throughput

0.479

High

159905

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

11

High-throughput

0.479

High

181574

TBXT
T-box transcription factor T

1

4

High-throughput

0.479

High

191146

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

8

High-throughput

0.479

High

210139

CRX
Cone-rod homeobox protein

1

17

High-throughput

0.479

High

225134

TLX3
T-cell leukemia homeobox protein 3

1

20

High-throughput

0.479

High

226615

TLX2
T-cell leukemia homeobox protein 2

1

19

High-throughput

0.479

High

260578

BRD4
Bromodomain-containing protein 4

1

9

High-throughput

0.479

High

320364

PHF14
PHD finger protein 14

1

5

High-throughput

0.479

High

406764

MYCN
N-myc proto-oncogene protein

1

14

High-throughput

0.479

High

419258

H2A1B
Histone H2A type 1-B/E

1

13

High-throughput

0.479

High

474349

NFIC
Nuclear factor 1 C-type

1

20

High-throughput

0.479

High

540964

ERG
Transcriptional regulator ERG

1

17

High-throughput

0.479

High

558470

XRCC6
X-ray repair cross-complementing protein 6

1

2

High-throughput

0.479

High

589960

RFA2
Replication protein A 32 kDa subunit

1

6

High-throughput

0.479

High

607191

CEBPB
CCAAT/enhancer-binding protein beta

1

11

High-throughput

0.479

High

696782

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

5

High-throughput

0.479

High

697283

APEX1
DNA repair nuclease/redox regulator APEX1

1

3

High-throughput

0.479

High

725332

TLX1
T-cell leukemia homeobox protein 1

1

20

High-throughput

0.479

High

755020

H2B1B
Histone H2B type 1-B

1

20

High-throughput

0.479

High

769434

RFA3
Replication protein A 14 kDa subunit

1

5

High-throughput

0.479

High

776145

SOX5
Transcription factor SOX-5

1

20

High-throughput

0.479

High

776262

SOX6
Transcription factor SOX-6

1

20

High-throughput

0.479

High

800151

COIL
Coilin

1

1

High-throughput

0.479

High

851818

NKX21
Homeobox protein Nkx-2.1

1

20

High-throughput

0.479

High

862518

YAP1
Transcriptional coactivator YAP1

1

14

High-throughput

0.479

High

883724

CENPA
Histone H3-like centromeric protein A

1

20

High-throughput

0.479

High

887301

CEBPA
CCAAT/enhancer-binding protein alpha

1

12

High-throughput

0.479

High

905250

MECP2
Methyl-CpG-binding protein 2

1

5

High-throughput

0.479

High

938515

PAX9
Paired box protein Pax-9

1

12

High-throughput

0.479

High

981163

H2B1C
Histone H2B type 1-C/E/F/G/I

1

20

High-throughput

0.479

High

986794

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

5

High-throughput

0.479

High

998915

H31
Histone H3.1

1

20

High-throughput

0.479

High

1017275

H33
Histone H3.3

1

20

High-throughput

0.479

High

1033289

EWS
RNA-binding protein EWS

1

5

High-throughput

0.479

High

1033806

PO5F1
POU domain, class 5, transcription factor 1

1

6

High-throughput

0.479

High

1048121

TLE3
Transducin-like enhancer protein 3

1

15

High-throughput

0.479

High

1083452

CPSF1
Cleavage and polyadenylation specificity factor subunit 1

1

1

High-throughput

0.479

High

1088076

NFIA
Nuclear factor 1 A-type

1

20

High-throughput

0.479

High

1097614

CBX3
Chromobox protein homolog 3

1

5

High-throughput

0.479

High

1128139

DHX8
ATP-dependent RNA helicase DHX8

1

3

High-throughput

0.479

High

1129773

MDC1
Mediator of DNA damage checkpoint protein 1

1

18

High-throughput

0.479

High

1133028

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

8

High-throughput

0.479

High

1133713

NFIX
Nuclear factor 1 X-type

1

20

High-throughput

0.479

High

1145846

IRF4
Interferon regulatory factor 4

1

6

High-throughput

0.479

High

1156889

E2F4
Transcription factor E2F4

1

9

High-throughput

0.479

High

1198220

PDCD4
Programmed cell death protein 4

1

1

High-throughput

0.479

High

1229123

RNF43
E3 ubiquitin-protein ligase RNF43

1

5

High-throughput

0.479

High

1289330

DTX2
Probable E3 ubiquitin-protein ligase DTX2

1

4

High-throughput

0.479

High

1313500

SMC5
Structural maintenance of chromosomes protein 5

1

6

High-throughput

0.479

High

1314468

SLX4
Structure-specific endonuclease subunit SLX4

1

14

High-throughput

0.479

High

1328990

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

1

High-throughput

0.479

High

1339219

NUP35
Nucleoporin NUP35

1

4

High-throughput

0.479

High

1351187

SP7
Transcription factor Sp7

1

15

High-throughput

0.479

High

1364001

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

3

High-throughput

0.479

High

1367509

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1387617

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

15

High-throughput

0.479

High

1405449

FEV
Protein FEV

1

17

High-throughput

0.479

High

1413237

SOX7
Transcription factor SOX-7

1

20

High-throughput

0.479

High

1413358

MTA3
Metastasis-associated protein MTA3

1

9

High-throughput

0.479

High

1428999

WWTR1
WW domain-containing transcription regulator protein 1

1

14

High-throughput

0.479

High

1434981

SOX17
Transcription factor SOX-17

1

20

High-throughput

0.479

High

1437227

NANOG
Homeobox protein NANOG

1

20

High-throughput

0.479

High

1448227

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

7

High-throughput

0.479

High

1452456

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

3

High-throughput

0.479

High

1458640

LHX3
LIM/homeobox protein Lhx3

1

12

High-throughput

0.479

High

1459195

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.479

High

1459651

XPO7
Exportin-7

1

4

High-throughput

0.479

High

1459652

NUP50
Nuclear pore complex protein Nup50

1

2

High-throughput

0.479

High

1459655

ASF1A
Histone chaperone ASF1A

1

5

High-throughput

0.479

High

1459656

ZN330
Zinc finger protein 330

1

4

High-throughput

0.479

High

657705

GCSP
Glycine dehydrogenase

1

0

High-throughput

0.458

High

807609

IF4A3
Eukaryotic initiation factor 4A-III

1

0

High-throughput

0.458

High

1415899

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.458

High

95907

E7EQY4
Metastasis-associated protein MTA3

1

9

High-throughput

0.445

High

344354

PTBP3
Polypyrimidine tract-binding protein 3

1

3

High-throughput

0.445

High

765973

BMI1
Polycomb complex protein BMI-1

1

9

High-throughput

0.445

High

1458998

DAXX
Death domain-associated protein 6

1

2

High-throughput

0.445

High

272529

OBSL1
Obscurin-like protein 1

1

11

High-throughput

0.437

High

1063677

GOGA2
Golgin subfamily A member 2

1

9

High-throughput

0.437

High

1252279

SYNE3
Nesprin-3

1

6

High-throughput

0.437

High

1445962

ALG13
UDP-N-acetylglucosamine transferase subunit ALG13

1

9

High-throughput

0.437

High

333766

FKBP9
Peptidyl-prolyl cis-trans isomerase FKBP9

3

0

High-throughput

0.345

High

347393

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.279

Low

483411

CLCB
Clathrin light chain B

1

0

High-throughput

0.279

Low

1158589

CDC37
Hsp90 co-chaperone Cdc37

1

0

High-throughput

0.279

Low

1409619

NIPS1
Protein NipSnap homolog 1

1

0

High-throughput

0.279

Low

1459654

CLC11
C-type lectin domain family 11 member A

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025