Protein: BEND3
BEN domain-containing protein 3

Gene: BEND3
Organism: Homo sapiens
Interactions: 119
UniProt ID: Q5T5X7

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000182 - rDNA binding
GO:0000183 - rDNA heterochromatin formation
GO:0000792 - heterochromatin
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1109798

HDAC1
Histone deacetylase 1

3

1

High-throughput

0.667

High

1213107

BEND3
BEN domain-containing protein 3

1

0

High-throughput

0.663

High

1213159

UBP21
Ubiquitin carboxyl-terminal hydrolase 21

2

0

Small-scale

0.585

High

1213160

TNIK
TRAF2 and NCK-interacting protein kinase

2

0

High-throughput

0.585

High

1213133

MCRS1
Microspherule protein 1

2

0

High-throughput

0.580

High

1213146

DPY30
Protein dpy-30 homolog

2

0

High-throughput

0.580

High

1213136

MA7D2
MAP7 domain-containing protein 2

2

2

High-throughput

0.574

High

1120191

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

2

0

High-throughput

0.559

High

1185250

F161A
Protein FAM161A

1

0

High-throughput

0.549

High

316885

MTA2
Metastasis-associated protein MTA2

1

2

High-throughput

0.536

High

340899

NFAC1
Nuclear factor of activated T-cells, cytoplasmic 1

1

1

High-throughput

0.536

High

854103

KI67
Proliferation marker protein Ki-67

1

1

High-throughput

0.536

High

1213128

HDAC2
Histone deacetylase 2

1

1

High-throughput

0.536

High

1213140

MTA3
Metastasis-associated protein MTA3

1

2

High-throughput

0.536

High

1213141

TRAF4
TNF receptor-associated factor 4

1

2

High-throughput

0.536

High

1213157

TRPS1
Zinc finger transcription factor Trps1

1

3

High-throughput

0.536

High

166160

AIM2
Interferon-inducible protein AIM2

1

0

High-throughput

0.513

High

284450

HSBP1
Heat shock factor-binding protein 1

1

0

High-throughput

0.513

High

586737

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.513

High

1054721

SUH
Recombining binding protein suppressor of hairless

1

0

High-throughput

0.513

High

1155965

ZFHX3
Zinc finger homeobox protein 3

1

0

High-throughput

0.513

High

1213113

CENPQ
Centromere protein Q

1

0

High-throughput

0.513

High

1213115

PIWL4
Piwi-like protein 4

1

0

High-throughput

0.513

High

1213116

P66A
Transcriptional repressor p66-alpha

1

0

High-throughput

0.513

High

1213142

RIOK2
Serine/threonine-protein kinase RIO2

1

0

High-throughput

0.513

High

1213145

FOXP3
Forkhead box protein P3

1

0

High-throughput

0.513

High

1213149

NOL6
Nucleolar protein 6

1

0

High-throughput

0.513

High

1213155

KANL3
KAT8 regulatory NSL complex subunit 3

1

0

High-throughput

0.513

High

1213163

RRP7A
Ribosomal RNA-processing protein 7 homolog A

1

0

High-throughput

0.513

High

300659

KRT37
Keratin, type I cuticular Ha7

1

1

High-throughput

0.489

High

300768

KRT38
Keratin, type I cuticular Ha8

1

1

High-throughput

0.489

High

1124468

MAP7
Ensconsin

1

2

High-throughput

0.489

High

1213112

TRAF7
E3 ubiquitin-protein ligase TRAF7

1

1

High-throughput

0.489

High

1213120

POC1A
POC1 centriolar protein homolog A

1

1

High-throughput

0.489

High

143039

NFIB
Nuclear factor 1 B-type

1

3

High-throughput

0.479

High

190947

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

1

High-throughput

0.479

High

243658

SMCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

1

1

Small-scale

0.479

High

474043

NFIC
Nuclear factor 1 C-type

1

3

High-throughput

0.479

High

487404

PARP1
Poly [ADP-ribose] polymerase 1

1

1

High-throughput

0.479

High

590439

GATA1
Erythroid transcription factor

1

3

High-throughput

0.479

High

606846

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

662594

GATA3
Trans-acting T-cell-specific transcription factor GATA-3

1

3

High-throughput

0.479

High

851586

GATA4
Transcription factor GATA-4

1

3

High-throughput

0.479

High

886937

CEBPA
CCAAT/enhancer-binding protein alpha

1

1

High-throughput

0.479

High

1066340

RBBP4
Histone-binding protein RBBP4

1

2

High-throughput

0.479

High

1087787

NFIA
Nuclear factor 1 A-type

1

3

High-throughput

0.479

High

1088869

TP53B
TP53-binding protein 1

1

1

High-throughput

0.479

High

1106342

NFAC2
Nuclear factor of activated T-cells, cytoplasmic 2

1

1

High-throughput

0.479

High

1129618

MDC1
Mediator of DNA damage checkpoint protein 1

1

1

High-throughput

0.479

High

1132751

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

1

High-throughput

0.479

High

1133451

NFIX
Nuclear factor 1 X-type

1

3

High-throughput

0.479

High

1158870

RBBP7
Histone-binding protein RBBP7

1

2

High-throughput

0.479

High

1213119

SLX4
Structure-specific endonuclease subunit SLX4

1

2

High-throughput

0.479

High

1213123

NUP43
Nucleoporin Nup43

1

4

High-throughput

0.479

High

1213130

PF21A
PHD finger protein 21A

1

2

High-throughput

0.479

High

1213132

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

1

High-throughput

0.479

High

1213134

CIC
Protein capicua homolog

1

1

High-throughput

0.479

High

1213148

SMRCD
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1

1

1

High-throughput

0.479

High

1213150

SP110
Sp110 nuclear body protein

1

3

High-throughput

0.479

High

1213161

RCOR1
REST corepressor 1

1

2

High-throughput

0.479

High

246655

KDM1A
Lysine-specific histone demethylase 1A

1

0

High-throughput

0.458

High

279390

TULP3
Tubby-related protein 3

1

0

High-throughput

0.458

High

323417

TRI37
E3 ubiquitin-protein ligase TRIM37

1

0

High-throughput

0.458

High

519386

MYB
Transcriptional activator Myb

1

0

High-throughput

0.458

High

685220

PAX6
Paired box protein Pax-6

1

0

High-throughput

0.458

High

862202

YAP1
Transcriptional coactivator YAP1

1

0

High-throughput

0.458

High

883572

CENPA
Histone H3-like centromeric protein A

1

0

High-throughput

0.458

High

886280

ARL4D
ADP-ribosylation factor-like protein 4D

1

0

High-throughput

0.458

High

979794

H4
Histone H4

1

0

High-throughput

0.458

High

1083378

CPSF1
Cleavage and polyadenylation specificity factor subunit 1

1

0

High-throughput

0.458

High

1155448

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.458

High

1213118

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

1213127

DCAF4
DDB1- and CUL4-associated factor 4

1

0

High-throughput

0.458

High

1213131

CHCH1
Small ribosomal subunit protein mS37

1

0

High-throughput

0.458

High

1213135

RANB9
Ran-binding protein 9

1

0

High-throughput

0.458

High

1213139

BARD1
BRCA1-associated RING domain protein 1

1

0

High-throughput

0.458

High

1213144

RT26
Small ribosomal subunit protein mS26

1

0

High-throughput

0.458

High

1213147

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

0

High-throughput

0.458

High

1213151

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

0

High-throughput

0.458

High

1213152

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.458

High

1213158

BAZ2A
Bromodomain adjacent to zinc finger domain protein 2A

1

0

Small-scale

0.458

High

1213162

ASF1A
Histone chaperone ASF1A

1

0

High-throughput

0.458

High

1213164

ZN330
Zinc finger protein 330

1

0

High-throughput

0.458

High

939195

SUMO3
Small ubiquitin-related modifier 3

1

1

Small-scale

0.445

High

991344

SUMO1
Small ubiquitin-related modifier 1

1

1

Small-scale

0.445

High

725146

HXC9
Homeobox protein Hox-C9

1

0

High-throughput

0.426

High

1213121

RN169
E3 ubiquitin-protein ligase RNF169

1

0

Small-scale

0.426

High

1213153

GRHL1
Grainyhead-like protein 1 homolog

1

0

High-throughput

0.426

High

1213122

MORN4
MORN repeat-containing protein 4

3

0

High-throughput

0.352

High

69787

ZN785
Zinc finger protein 785

2

0

High-throughput

0.328

High

506164

UBFL1
Upstream-binding factor 1-like protein 1

2

0

High-throughput

0.316

High

134313

RPOM
DNA-directed RNA polymerase, mitochondrial

1

0

High-throughput

0.279

Low

1065813

SLFN5
Schlafen family member 5

1

0

High-throughput

0.279

Low

1111916

SNX1
Sorting nexin-1

1

0

High-throughput

0.279

Low

1179790

INSY1
Inhibitory synaptic factor 1

1

0

High-throughput

0.279

Low

1213110

DEN5A
DENN domain-containing protein 5A

1

0

High-throughput

0.279

Low

1213124

FA81A
Protein FAM81A

1

0

High-throughput

0.279

Low

1213126

CERK1
Ceramide kinase

1

0

High-throughput

0.279

Low

1213137

IMP2L
Mitochondrial inner membrane protease subunit 2

1

0

High-throughput

0.279

Low

1213154

CFA97
Cilia- and flagella-associated protein 97

1

0

High-throughput

0.279

Low

1142292

PDIA6
Protein disulfide-isomerase A6

1

0

High-throughput

0.269

Low

157482

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.249

Low

412062

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

519133

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.249

Low

1025922

NDP
Norrin

1

0

Small-scale

0.249

Low

1071161

ARL16
ADP-ribosylation factor-like protein 16

1

0

High-throughput

0.249

Low

1132271

GOGB1
Golgin subfamily B member 1

1

0

High-throughput

0.249

Low

1213108

DCA12
DDB1- and CUL4-associated factor 12

1

0

High-throughput

0.249

Low

1213111

CH082
UPF0598 protein C8orf82

1

0

High-throughput

0.249

Low

1213114

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

1213117

DHX40
Probable ATP-dependent RNA helicase DHX40

1

0

High-throughput

0.249

Low

1213129

VP33A
Vacuolar protein sorting-associated protein 33A

1

0

High-throughput

0.249

Low

1213138

FEV
Protein FEV

1

0

High-throughput

0.249

Low

1213143

KLF16
Krueppel-like factor 16

1

0

High-throughput

0.249

Low

1213156

ZMYM2
Zinc finger MYM-type protein 2

1

0

High-throughput

0.249

Low

1213109

CP135
Centrosomal protein of 135 kDa

1

0

High-throughput

0.232

Low

1213125

MYBPP
MYCBP-associated protein

1

0

High-throughput

0.232

Low

1213165

PCDG9
Protocadherin gamma-A9

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025