Protein: CENPB
Major centromere autoantigen B (Centromere protein B) (CENP-B)

Gene: CENPB
Organism: Homo sapiens
Interactions: 137
UniProt ID: P07199

Gene Ontology (top 5):
GO:0000775 - chromosome, centromeric region
GO:0000779 - condensed chromosome, centromeric region
GO:0003677 - DNA binding
GO:0003682 - chromatin binding
GO:0003696 - satellite DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

451555

ZN707
Zinc finger protein 707

3

11

High-throughput

0.667

High

451496

CSK2B
Casein kinase II subunit beta

3

1

High-throughput

0.646

High

139468

PESC
Pescadillo homolog

3

0

High-throughput

0.634

High

171826

ZN263
Zinc finger protein 263

2

8

High-throughput

0.628

High

212794

ZN264
Zinc finger protein 264

2

8

High-throughput

0.628

High

451501

ZN816
Zinc finger protein 816

2

2

High-throughput

0.628

High

451511

ZN169
Zinc finger protein 169

2

7

High-throughput

0.628

High

451518

ZN311
Zinc finger protein 311

2

2

High-throughput

0.628

High

451522

ZN544
Zinc finger protein 544

2

2

High-throughput

0.628

High

451531

ZN550
Zinc finger protein 550

2

10

High-throughput

0.628

High

451536

Z354C
Zinc finger protein 354C

2

4

High-throughput

0.628

High

451553

ZN669
Zinc finger protein 669

2

12

High-throughput

0.628

High

451571

ZN408
Zinc finger protein 408

2

7

High-throughput

0.628

High

451577

ZN331
Zinc finger protein 331

2

8

High-throughput

0.628

High

451586

ZN223
Zinc finger protein 223

2

5

High-throughput

0.628

High

451588

ZN214
Zinc finger protein 214

2

2

High-throughput

0.628

High

330577

KI20A
Kinesin-like protein KIF20A

2

1

High-throughput

0.611

High

451562

PI51A
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha

2

2

High-throughput

0.611

High

451544

TSYL6
Testis-specific Y-encoded-like protein 6

2

0

High-throughput

0.602

High

451580

TAP26
Thyroid transcription factor 1-associated protein 26

2

0

High-throughput

0.602

High

451584

DAXX
Death domain-associated protein 6

2

1

Small-scale

0.584

High

451591

ABT1
Activator of basal transcription 1

2

0

High-throughput

0.576

High

451491

CENPA
Histone H3-like centromeric protein A

2

5

Small-scale

0.571

High

403739

GCR
Glucocorticoid receptor

1

5

High-throughput

0.561

High

451507

SQSTM
Sequestosome-1

2

0

High-throughput

0.559

High

451546

SYT2
Synaptotagmin-2

2

1

High-throughput

0.549

High

451487

RL22
Large ribosomal subunit protein eL22

2

0

High-throughput

0.547

High

49557

FEZF1
Fez family zinc finger protein 1

1

11

High-throughput

0.536

High

451473

ZBT48
Zinc finger and BTB domain-containing protein 48

1

4

High-throughput

0.536

High

451474

GLI4
Zinc finger protein GLI4

1

13

High-throughput

0.536

High

451476

ZNF17
Zinc finger protein 17

1

6

High-throughput

0.536

High

451492

CTCF
Transcriptional repressor CTCF

1

9

High-throughput

0.536

High

451498

ZXDB
Zinc finger X-linked protein ZXDB

1

10

High-throughput

0.536

High

451499

HME1
Homeobox protein engrailed-1

1

2

High-throughput

0.536

High

451500

ZN543
Zinc finger protein 543

1

6

High-throughput

0.536

High

451502

FOXF2
Forkhead box protein F2

1

3

High-throughput

0.536

High

451503

FOXL1
Forkhead box protein L1

1

2

High-throughput

0.536

High

451510

ZN460
Zinc finger protein 460

1

5

High-throughput

0.536

High

451513

ZKSC8
Zinc finger protein with KRAB and SCAN domains 8

1

6

High-throughput

0.536

High

451526

ZN517
Zinc finger protein 517

1

5

High-throughput

0.536

High

451528

ZN574
Zinc finger protein 574

1

3

High-throughput

0.536

High

451535

ZN677
Zinc finger protein 677

1

2

High-throughput

0.536

High

451539

ASPM
Abnormal spindle-like microcephaly-associated protein

1

1

High-throughput

0.536

High

451541

ZN687
Zinc finger protein 687

1

2

High-throughput

0.536

High

451549

ZN418
Zinc finger protein 418

1

5

High-throughput

0.536

High

451552

TRI52
E3 ubiquitin-protein ligase TRIM52

1

4

High-throughput

0.536

High

451559

ZN514
Zinc finger protein 514

1

10

High-throughput

0.536

High

451561

KIF2C
Kinesin-like protein KIF2C

1

1

High-throughput

0.536

High

451566

ZN416
Zinc finger protein 416

1

6

High-throughput

0.536

High

451568

FOXP3
Forkhead box protein P3

1

3

High-throughput

0.536

High

451573

CBX8
Chromobox protein homolog 8

1

7

High-throughput

0.536

High

451576

TF7L2
Transcription factor 7-like 2

1

6

High-throughput

0.536

High

451592

NP1L2
Nucleosome assembly protein 1-like 2

1

1

High-throughput

0.536

High

451594

ASF1A
Histone chaperone ASF1A

1

2

High-throughput

0.536

High

451563

SH23A
SH2 domain-containing protein 3A

2

1

High-throughput

0.526

High

451471

ADRB2
Beta-2 adrenergic receptor

1

0

High-throughput

0.518

High

451581

ZFAT
Zinc finger protein ZFAT

1

8

Small-scale

0.515

High

451481

H1T
Histone H1t

1

0

High-throughput

0.513

High

451485

MPIP2
M-phase inducer phosphatase 2

1

0

High-throughput

0.513

High

451486

ARRB2
Beta-arrestin-2

1

0

High-throughput

0.513

High

451570

TAF1D
TATA box-binding protein-associated factor RNA polymerase I subunit D

1

0

High-throughput

0.513

High

451579

SHFL
Shiftless antiviral inhibitor of ribosomal frameshifting protein

1

0

High-throughput

0.513

High

451593

PHF8
Histone lysine demethylase PHF8

1

0

High-throughput

0.513

High

451478

ANXA7
Annexin A7

1

1

High-throughput

0.508

High

451520

GFI1B
Zinc finger protein Gfi-1b

1

13

High-throughput

0.508

High

421310

A4
Amyloid-beta precursor protein

1

5

High-throughput

0.501

High

451490

TFPI2
Tissue factor pathway inhibitor 2

1

5

High-throughput

0.489

High

451533

PNM8A
Paraneoplastic antigen-like protein 8A

1

3

High-throughput

0.489

High

451565

MAD3
Max dimerization protein 3

1

2

High-throughput

0.489

High

405378

KITH
Thymidine kinase, cytosolic

1

0

High-throughput

0.486

High

451483

GA45A
Growth arrest and DNA damage-inducible protein GADD45 alpha

1

0

High-throughput

0.486

High

451489

CDN1A
Cyclin-dependent kinase inhibitor 1

1

0

High-throughput

0.486

High

451493

GSK3B
Glycogen synthase kinase-3 beta

1

0

High-throughput

0.486

High

451508

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

0

High-throughput

0.486

High

451514

SMN
Survival motor neuron protein

1

0

High-throughput

0.486

High

451587

KS6A6
Ribosomal protein S6 kinase alpha-6

1

0

High-throughput

0.486

High

284787

TADA3
Transcriptional adapter 3

1

0

Small-scale

0.480

High

451517

CENPW
Centromere protein W

1

0

Small-scale

0.480

High

451548

FBX25
F-box only protein 25

1

0

Small-scale

0.480

High

259316

BRD4
Bromodomain-containing protein 4

1

3

High-throughput

0.479

High

277518

H2AY
Core histone macro-H2A.1

1

3

High-throughput

0.479

High

451472

PARP1
Poly [ADP-ribose] polymerase 1

1

3

Small-scale

0.479

High

451475

ETS1
Protein C-ets-1

1

5

High-throughput

0.479

High

451482

NR4A1
Nuclear receptor subfamily 4immunitygroup A member 1

1

5

High-throughput

0.479

High

451484

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

451488

BRCA1
Breast cancer type 1 susceptibility protein

1

1

High-throughput

0.479

High

451497

ZXDA
Zinc finger X-linked protein ZXDA

1

10

Small-scale

0.479

High

451509

CUL3
Cullin-3

1

1

High-throughput

0.479

High

451515

IF16
Gamma-interferon-inducible protein 16

1

1

High-throughput

0.479

High

451521

IFIX
Pyrin and HIN domain-containing protein 1

1

1

High-throughput

0.479

High

451530

H32
Histone H3.2

1

5

Small-scale

0.479

High

451538

SLX4
Structure-specific endonuclease subunit SLX4

1

6

High-throughput

0.479

High

451543

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

9

High-throughput

0.479

High

451551

KAT6A
Histone acetyltransferase KAT6A

1

3

High-throughput

0.479

High

451556

DCPS
m7GpppX diphosphatase

1

1

High-throughput

0.479

High

451557

OPTN
Optineurin

1

2

High-throughput

0.479

High

451560

RING2
E3 ubiquitin-protein ligase RING2

1

3

High-throughput

0.479

High

451567

FACD2
Fanconi anemia group D2 protein

1

2

High-throughput

0.479

High

451572

SP110
Sp110 nuclear body protein

1

4

High-throughput

0.479

High

451585

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.479

High

451589

BRPF3
Bromodomain and PHD finger-containing protein 3

1

1

High-throughput

0.479

High

451494

HAND2
Heart- and neural crest derivatives-expressed protein 2

1

0

Small-scale

0.460

High

451504

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

0

High-throughput

0.458

High

451506

G3BP1
Ras GTPase-activating protein-binding protein 1

1

0

High-throughput

0.458

High

451512

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

451545

CGAS
Cyclic GMP-AMP synthase

1

0

High-throughput

0.458

High

451574

MOV10
Helicase MOV-10

1

0

High-throughput

0.458

High

451477

ZNF24
Zinc finger protein 24

1

9

High-throughput

0.445

High

451519

ZN484
Zinc finger protein 484

1

1

High-throughput

0.445

High

451524

ZFP1
Zinc finger protein 1 homolog

1

9

High-throughput

0.445

High

451525

ZN549
Zinc finger protein 549

1

6

High-throughput

0.445

High

451527

ZN793
Zinc finger protein 793

1

13

High-throughput

0.445

High

451540

ZN567
Zinc finger protein 567

1

3

High-throughput

0.445

High

451542

ZN561
Zinc finger protein 561

1

5

High-throughput

0.445

High

451558

ZN333
Zinc finger protein 333

1

7

High-throughput

0.445

High

451564

ZN577
Zinc finger protein 577

1

11

High-throughput

0.445

High

451575

ZFP14
Zinc finger protein 14 homolog

1

4

High-throughput

0.445

High

451578

ZFP57
Zinc finger protein 57 homolog

1

7

High-throughput

0.445

High

451569

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.437

High

70993

ZN724
Zinc finger protein 724

1

0

High-throughput

0.426

High

451523

CAVN1
Caveolae-associated protein 1

1

0

High-throughput

0.426

High

451547

IN80E
INO80 complex subunit E

1

0

High-throughput

0.426

High

451595

RRP7A
Ribosomal RNA-processing protein 7 homolog A

1

0

High-throughput

0.426

High

451480

SYT1
Synaptotagmin-1

1

1

High-throughput

0.407

High

451516

KNOP1
Lysine-rich nucleolar protein 1

2

0

High-throughput

0.328

High

451534

LRRT4
Leucine-rich repeat transmembrane neuronal protein 4

2

0

High-throughput

0.313

High

451505

NOGG
Noggin

1

0

High-throughput

0.279

Low

451529

PLPL7
Patatin-like phospholipase domain-containing protein 7

1

0

High-throughput

0.279

Low

451532

NOP9
Nucleolar protein 9

1

0

High-throughput

0.279

Low

451537

SULF2
Extracellular sulfatase Sulf-2

1

0

High-throughput

0.279

Low

451550

HPSE2
Inactive heparanase-2

1

0

High-throughput

0.279

Low

451582

MAP10
Microtubule-associated protein 10

1

0

High-throughput

0.279

Low

451583

DKK2
Dickkopf-related protein 2

1

0

High-throughput

0.279

Low

451479

TKN1
Protachykinin-1

1

0

High-throughput

0.265

Low

451495

AP2B1
AP-2 complex subunit beta

1

0

High-throughput

0.261

Low

451590

HECD1
E3 ubiquitin-protein ligase HECTD1

1

0

High-throughput

0.249

Low

451554

CC049
Putative uncharacterized protein C3orf49

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025