Protein: PLIN3
Perilipin-3 (47 kDa mannose 6-phosphate receptor-binding protein) (47 kDa MPR-binding protein) (Cargo selection protein TIP47) (Mannose-6-phosphate receptor-binding protein 1) (Placental protein 17) (PP17)

Gene: PLIN3
Organism: Homo sapiens
Interactions: 100
UniProt ID: O60664

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005768 - endosome
GO:0005794 - Golgi apparatus
GO:0005811 - lipid droplet
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

253102

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

3

0

High-throughput

0.646

High

253066

CCHL
Holocytochrome c-type synthase

3

0

High-throughput

0.638

High

253104

PMYT1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase

3

0

High-throughput

0.638

High

253093

SPART
Spartin

2

1

Small-scale

0.625

High

253050

MPRD
Cation-dependent mannose-6-phosphate receptor

2

0

Small-scale

0.609

High

226296

SNG1
Synaptogyrin-1

2

1

High-throughput

0.606

High

226466

SNG3
Synaptogyrin-3

2

1

High-throughput

0.606

High

253032

SNX2
Sorting nexin-2

2

2

High-throughput

0.606

High

253036

SFT2B
Vesicle transport protein SFT2B

2

1

High-throughput

0.606

High

253079

SNX1
Sorting nexin-1

2

2

High-throughput

0.606

High

253095

ABHD4
(Lyso)-N-acylphosphatidylethanolamine lipase

2

6

High-throughput

0.606

High

253097

ABHD5
1-acylglycerol-3-phosphate O-acyltransferase ABHD5

2

6

High-throughput

0.606

High

253117

TBC13
TBC1 domain family member 13

2

1

High-throughput

0.606

High

253103

RUSF1
RUS family member 1

2

0

High-throughput

0.602

High

253031

PLIN3
Perilipin-3

2

1

Small-scale

0.595

High

253043

MPRI
Cation-independent mannose-6-phosphate receptor

2

0

Small-scale

0.588

High

253062

PTN9
Tyrosine-protein phosphatase non-receptor type 9

2

0

High-throughput

0.580

High

253075

DCE2
Glutamate decarboxylase 2

2

0

High-throughput

0.580

High

253089

DHB13
17-beta-hydroxysteroid dehydrogenase 13

2

0

High-throughput

0.580

High

253109

LNP
Endoplasmic reticulum junction formation protein lunapark

2

0

High-throughput

0.580

High

253111

CHM4B
Charged multivesicular body protein 4b

2

0

High-throughput

0.580

High

253055

SHC1
SHC-transforming protein 1

2

1

High-throughput

0.571

High

253067

HSP72
Heat shock-related 70 kDa protein 2

1

3

High-throughput

0.536

High

253033

PR40A
Pre-mRNA-processing factor 40 homolog A

1

1

High-throughput

0.515

High

253069

CASP6
Caspase-6

1

2

High-throughput

0.515

High

253123

SHLB1
Endophilin-B1

1

1

High-throughput

0.515

High

253035

RHBT3
Rho-related BTB domain-containing protein 3

1

0

Small-scale

0.513

High

253048

AATC
Aspartate aminotransferase, cytoplasmic

1

0

High-throughput

0.513

High

253083

ZSC26
Zinc finger and SCAN domain-containing protein 26

1

0

High-throughput

0.513

High

253034

CBPD
Carboxypeptidase D

1

1

Small-scale

0.501

High

253041

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.501

High

253071

MAX
Protein max

1

1

High-throughput

0.494

High

253046

LAMP2
Lysosome-associated membrane glycoprotein 2

1

0

High-throughput

0.493

High

253112

MYG1
MYG1 exonuclease

1

0

High-throughput

0.493

High

253038

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.489

High

253040

FIBG
Fibrinogen gamma chain

1

1

High-throughput

0.489

High

253081

SMAD2
Mothers against decapentaplegic homolog 2

1

0

High-throughput

0.486

High

253065

RAB9A
Ras-related protein Rab-9A

1

0

Small-scale

0.480

High

217588

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.479

High

240233

PRKN
E3 ubiquitin-protein ligase parkin

1

3

High-throughput

0.479

High

253049

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

253056

GPC1
Glypican-1 [Cleaved into: Secreted glypican-1]

1

1

High-throughput

0.479

High

253058

SYUA
Alpha-synuclein

1

1

High-throughput

0.479

High

253063

YAP1
Transcriptional coactivator YAP1

1

1

High-throughput

0.479

High

253076

LIPS
Hormone-sensitive lipase

1

4

Small-scale

0.479

High

253077

FOXO1
Forkhead box protein O1

1

1

High-throughput

0.479

High

253078

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

2

High-throughput

0.479

High

253098

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

1

High-throughput

0.479

High

253100

PLPL2
Patatin-like phospholipase domain-containing protein 2

1

3

Small-scale

0.479

High

253110

WWTR1
WW domain-containing transcription regulator protein 1

1

1

High-throughput

0.479

High

253120

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

253101

Q96AL5
PBX3 protein

1

1

High-throughput

0.470

High

253037

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

253039

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

1

0

High-throughput

0.458

High

253044

CADH1
Cadherin-1

1

0

High-throughput

0.458

High

253047

CREB1
Cyclic AMP-responsive element-binding protein 1

1

0

High-throughput

0.458

High

253051

VDAC1
Non-selective voltage-gated ion channel VDAC1

1

0

High-throughput

0.458

High

253052

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

0

High-throughput

0.458

High

253059

BRCA1
Breast cancer type 1 susceptibility protein

1

0

High-throughput

0.458

High

253074

H2B1C
Histone H2B type 1-C/E/F/G/I

1

0

High-throughput

0.458

High

253080

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

253085

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

253087

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

253091

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

253092

FA20C
Extracellular serine/threonine protein kinase FAM20C

1

0

High-throughput

0.458

High

253096

ACMSD
2-amino-3-carboxymuconate-6-semialdehyde decarboxylase

1

0

High-throughput

0.458

High

253099

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

253106

TMM43
Transmembrane protein 43

1

0

High-throughput

0.458

High

253113

MYO10
Unconventional myosin-X

1

0

Small-scale

0.458

High

253118

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.458

High

253121

UBQL2
Ubiquilin-2

1

0

High-throughput

0.458

High

253124

MTCH2
Mitochondrial carrier homolog 2

1

0

High-throughput

0.458

High

253070

CD81
CD81 antigen

1

1

High-throughput

0.445

High

253060

PBX3
Pre-B-cell leukemia transcription factor 3

1

1

High-throughput

0.439

High

253073

TBPL1
TATA box-binding protein-like 1

1

0

High-throughput

0.438

High

253045

LYL1
Protein lyl-1

1

1

High-throughput

0.437

High

253072

WDR5
WD repeat-containing protein 5

1

1

High-throughput

0.437

High

253068

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.426

High

253086

PKHA7
Pleckstrin homology domain-containing family A member 7

1

0

High-throughput

0.426

High

253116

S17A5
Sialin

1

0

High-throughput

0.426

High

253064

CEBPA
CCAAT/enhancer-binding protein alpha

1

1

High-throughput

0.373

High

253061

VIPR2
Vasoactive intestinal polypeptide receptor 2

2

0

High-throughput

0.328

High

253042

SYPH
Synaptophysin

2

0

High-throughput

0.316

High

253053

CCNC
Cyclin-C

2

0

High-throughput

0.316

High

253105

CYBC1
Cytochrome b-245 chaperone 1

2

0

High-throughput

0.316

High

253107

SYTM
Threonine--tRNA ligase, mitochondrial

2

0

High-throughput

0.316

High

253115

MID51
Mitochondrial dynamics protein MIEF1

2

0

High-throughput

0.316

High

253119

TM14C
Transmembrane protein 14C

2

0

High-throughput

0.316

High

253125

PIAS3
E3 SUMO-protein ligase PIAS3

2

0

High-throughput

0.316

High

253094

FA24B
Protein FAM24B

1

0

High-throughput

0.279

Low

253108

TX101
Testis-expressed protein 101

1

0

High-throughput

0.279

Low

253114

TF7L2
Transcription factor 7-like 2

1

0

High-throughput

0.279

Low

253090

ZER1
Protein zer-1 homolog

1

0

High-throughput

0.269

Low

253054

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

253057

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

253082

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.249

Low

253084

DCA15
DDB1- and CUL4-associated factor 15

1

0

High-throughput

0.249

Low

253088

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

253122

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025