Protein: ATPF1
ATP synthase mitochondrial F1 complex assembly factor 1 (ATP11 homolog)

Gene: ATPF1, ATPAF1
Organism: Homo sapiens
Interactions: 117
UniProt ID: Q5TC12

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0033615 - mitochondrial proton-transporting ATP synthase complex assembly
GO:0140777 - protein-containing complex stabilizing activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

443825

ATPB
ATP synthase F(1) complex subunit beta, mitochondrial

5

2

Small-scale

0.716

High

288959

ERAL1
GTPase Era, mitochondrial

3

1

High-throughput

0.667

High

1215587

RUSD3
Mitochondrial mRNA pseudouridine synthase RPUSD3

2

1

High-throughput

0.611

High

361640

OTC
Ornithine transcarbamylase, mitochondrial

2

0

High-throughput

0.585

High

1215607

RRFM
Ribosome-recycling factor, mitochondrial

2

0

High-throughput

0.585

High

1215628

MTG2
Mitochondrial ribosome-associated GTPase 2

2

0

High-throughput

0.585

High

279789

CISY
Citrate synthase, mitochondrial

2

0

High-throughput

0.559

High

348546

AIFM1
Apoptosis-inducing factor 1, mitochondrial

2

0

High-throughput

0.559

High

1087415

GRSF1
G-rich sequence factor 1

2

0

High-throughput

0.559

High

1162364

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

2

0

High-throughput

0.559

High

275308

NDUS7
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial

1

0

High-throughput

0.513

High

946495

YBEY
Endoribonuclease YbeY

1

0

High-throughput

0.513

High

1100609

DHRS2
Dehydrogenase/reductase SDR family member 2, mitochondrial

1

0

High-throughput

0.513

High

1106427

TOP3A
DNA topoisomerase 3-alpha

1

0

High-throughput

0.513

High

1215586

ACSM5
Acyl-coenzyme A synthetase ACSM5, mitochondrial

1

0

High-throughput

0.513

High

1215589

FAHD1
Oxaloacetate tautomerase FAHD1, mitochondrial

1

0

High-throughput

0.513

High

1215610

MASU1
Mitochondrial assembly of ribosomal large subunit protein 1

1

0

High-throughput

0.513

High

1215617

MACD1
ADP-ribose glycohydrolase MACROD1

1

0

High-throughput

0.513

High

1215622

SCOT2
Succinyl-CoA:3-ketoacid coenzyme A transferase 2, mitochondrial

1

0

High-throughput

0.513

High

1215644

MRM2
rRNA methyltransferase 2, mitochondrial

1

0

High-throughput

0.513

High

1215645

SYYM
Tyrosine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

281975

MPPB
Mitochondrial-processing peptidase subunit beta

1

1

High-throughput

0.479

High

287308

RF1M
Peptide chain release factor 1, mitochondrial

1

2

High-throughput

0.479

High

856283

IF2M
Translation initiation factor IF-2, mitochondrial

1

1

High-throughput

0.479

High

1083637

MPPA
Mitochondrial-processing peptidase subunit alpha

1

1

High-throughput

0.479

High

1135893

FAKD3
FAST kinase domain-containing protein 3, mitochondrial

1

3

High-throughput

0.479

High

1215592

FAKD5
FAST kinase domain-containing protein 5, mitochondrial

1

3

High-throughput

0.479

High

1215595

MIRO2
Mitochondrial Rho GTPase 2

1

1

High-throughput

0.479

High

1215599

MCU
Calcium uniporter protein, mitochondrial

1

1

High-throughput

0.479

High

1215601

RRF2M
Ribosome-releasing factor 2, mitochondrial

1

1

High-throughput

0.479

High

1215602

FAKD4
FAST kinase domain-containing protein 4

1

3

High-throughput

0.479

High

1215604

MCUR1
Mitochondrial calcium uniporter regulator 1

1

1

High-throughput

0.479

High

1215605

RUSD4
Pseudouridylate synthase RPUSD4, mitochondrial

1

1

High-throughput

0.479

High

1215606

TIM14
Mitochondrial import inner membrane translocase subunit TIM14

1

1

High-throughput

0.479

High

1215612

IMP1L
Mitochondrial inner membrane protease subunit 1

1

1

High-throughput

0.479

High

1215614

EFGM
Elongation factor G, mitochondrial

1

1

High-throughput

0.479

High

1215615

IMP2L
Mitochondrial inner membrane protease subunit 2

1

1

High-throughput

0.479

High

1215624

CC90B
Coiled-coil domain-containing protein 90B, mitochondrial

1

1

High-throughput

0.479

High

1215627

MTRFR
Mitochondrial translation release factor in rescue

1

2

High-throughput

0.479

High

1215637

MCUB
Calcium uniporter regulatory subunit MCUb, mitochondrial

1

1

High-throughput

0.479

High

1215640

FAKD2
FAST kinase domain-containing protein 2, mitochondrial

1

3

High-throughput

0.479

High

1215641

MTCH1
Mitochondrial carrier homolog 1

1

1

High-throughput

0.479

High

1215643

RF1ML
Peptide chain release factor 1-like, mitochondrial

1

2

High-throughput

0.479

High

1215649

DJC15
DnaJ homolog subfamily C member 15

1

1

High-throughput

0.479

High

1215650

MTCH2
Mitochondrial carrier homolog 2

1

1

High-throughput

0.479

High

61523

VWA8
von Willebrand factor A domain-containing protein 8

1

0

High-throughput

0.458

High

66216

MET15
12S rRNA N(4)-cytidine methyltransferase METTL15

1

0

High-throughput

0.458

High

183662

RT12
Small ribosomal subunit protein uS12m

1

0

High-throughput

0.458

High

216714

HTRA2
Serine protease HTRA2, mitochondrial

1

0

High-throughput

0.458

High

350894

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

1

0

High-throughput

0.458

High

471074

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

0

High-throughput

0.458

High

519134

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.458

High

532651

CH60
60 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.458

High

786125

LONM
Lon protease homolog, mitochondrial

1

0

High-throughput

0.458

High

828803

MDHM
Malate dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

841779

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

0

High-throughput

0.458

High

851916

EFTS
Elongation factor Ts, mitochondrial

1

0

High-throughput

0.458

High

882719

EFTU
Elongation factor Tu, mitochondrial

1

0

High-throughput

0.458

High

1013400

LACTB
Serine beta-lactamase-like protein LACTB, mitochondrial

1

0

High-throughput

0.458

High

1024068

TFAM
Transcription factor A, mitochondrial

1

0

High-throughput

0.458

High

1048552

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1058067

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1062823

QOR
Quinone oxidoreductase

1

0

High-throughput

0.458

High

1090429

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

0

High-throughput

0.458

High

1117755

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

0

High-throughput

0.458

High

1123314

ICT1
Large ribosomal subunit protein mL62

1

0

High-throughput

0.458

High

1125478

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

0

High-throughput

0.458

High

1142566

PDK1
[Pyruvate dehydrogenase

1

0

High-throughput

0.458

High

1147609

TOM20
Mitochondrial import receptor subunit TOM20 homolog

1

0

High-throughput

0.458

High

1149579

SURF1
Surfeit locus protein 1

1

0

High-throughput

0.458

High

1207035

SYAM
Alanine--tRNA ligase, mitochondrial

1

0

High-throughput

0.458

High

1215585

MRM1
rRNA methyltransferase 1, mitochondrial

1

0

High-throughput

0.458

High

1215588

CH082
UPF0598 protein C8orf82

1

0

High-throughput

0.458

High

1215591

DHX30
ATP-dependent RNA helicase DHX30

1

0

High-throughput

0.458

High

1215593

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.458

High

1215600

AKAP1
A-kinase anchor protein 1, mitochondrial

1

0

High-throughput

0.458

High

1215603

S2546
Mitochondrial outer membrane protein SLC25A46

1

0

High-throughput

0.458

High

1215608

MTEF3
Transcription termination factor 3, mitochondrial

1

0

High-throughput

0.458

High

1215609

OMA1
Metalloendopeptidase OMA1, mitochondrial

1

0

High-throughput

0.458

High

1215611

COX14
Cytochrome c oxidase assembly protein COX14

1

0

High-throughput

0.458

High

1215613

TEFM
Transcription elongation factor, mitochondrial

1

0

High-throughput

0.458

High

1215616

RMD3
Regulator of microtubule dynamics protein 3

1

0

High-throughput

0.458

High

1215618

TACO1
Translational activator of cytochrome c oxidase 1

1

0

High-throughput

0.458

High

1215619

TMM70
Transmembrane protein 70, mitochondrial

1

0

High-throughput

0.458

High

1215620

TR61B
tRNA

1

0

High-throughput

0.458

High

1215621

HINT2
Adenosine 5'-monophosphoramidase HINT2

1

0

High-throughput

0.458

High

1215623

RT26
Small ribosomal subunit protein mS26

1

0

High-throughput

0.458

High

1215625

IF3M
Translation initiation factor IF-3, mitochondrial

1

0

High-throughput

0.458

High

1215626

PARL
Presenilin-associated rhomboid-like protein, mitochondrial

1

0

High-throughput

0.458

High

1215629

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.458

High

1215630

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

0

High-throughput

0.458

High

1215631

NGRN
Neugrin

1

0

High-throughput

0.458

High

1215633

TOM22
Mitochondrial import receptor subunit TOM22 homolog

1

0

High-throughput

0.458

High

1215635

DDX28
Probable ATP-dependent RNA helicase DDX28

1

0

High-throughput

0.458

High

1215636

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

0

High-throughput

0.458

High

1215638

AKIP
Small ribosomal subunit protein mS38

1

0

High-throughput

0.458

High

1215639

OCAD1
OCIA domain-containing protein 1

1

0

High-throughput

0.458

High

1215642

MRES1
Mitochondrial transcription rescue factor 1

1

0

High-throughput

0.458

High

1215646

RM11
Large ribosomal subunit protein uL11m

1

0

High-throughput

0.458

High

1215647

FIS1
Mitochondrial fission 1 protein

1

0

High-throughput

0.458

High

1215648

PTH2
Peptidyl-tRNA hydrolase 2, mitochondrial

1

0

High-throughput

0.458

High

653370

HEMH
Ferrochelatase, mitochondrial

1

0

High-throughput

0.426

High

1215598

KDF1
Keratinocyte differentiation factor 1

1

0

High-throughput

0.279

Low

1215634

RAD18
E3 ubiquitin-protein ligase RAD18

1

0

High-throughput

0.279

Low

277933

SH3L1
Adapter SH3BGRL

1

0

Small-scale

0.249

Low

341077

DIRA3
GTP-binding protein Di-Ras3

1

0

High-throughput

0.249

Low

588887

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

695667

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

768391

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

1015508

RHOG
Rho-related GTP-binding protein RhoG

1

0

High-throughput

0.249

Low

1215590

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1215596

TM192
Transmembrane protein 192

1

0

High-throughput

0.249

Low

1215597

CGAS
Cyclic GMP-AMP synthase

1

0

Small-scale

0.249

Low

1215632

PXMP2
Peroxisomal membrane protein 2

1

0

High-throughput

0.249

Low

183937

S22A2
Solute carrier family 22 member 2

1

0

High-throughput

0.232

Low

1215584

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.232

Low

1215594

SULF2
Extracellular sulfatase Sulf-2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025