Protein: DCTN4
Dynactin subunit 4 (Dyn4) (Dynactin subunit p62)

Gene: DCTN4
Organism: Homo sapiens
Interactions: 108
UniProt ID: Q9UJW0

Gene Ontology (top 5):
GO:0000776 - kinetochore
GO:0000922 - spindle pole
GO:0001725 - stress fiber
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

785580

ACTY
Beta-centractin

4

5

High-throughput

0.895

High

897150

ACTZ
Alpha-centractin

4

5

Small-scale

0.890

High

1348819

ARP10
Actin-related protein 10

3

4

High-throughput

0.843

High

892100

ACTB
Actin, cytoplasmic 1

2

2

High-throughput

0.789

High

930046

ACTG
Actin, cytoplasmic 2

2

2

High-throughput

0.789

High

1039355

DCTN2
Dynactin subunit 2

6

1

High-throughput

0.736

High

1051505

DCTN1
Dynactin subunit 1

6

2

High-throughput

0.733

High

813200

CAZA2
F-actin-capping protein subunit alpha-2

4

1

High-throughput

0.699

High

932440

ACTC
Actin, alpha cardiac muscle 1

1

2

High-throughput

0.665

High

813828

CAPZB
F-actin-capping protein subunit beta

3

1

High-throughput

0.656

High

1033354

DC1I2
Cytoplasmic dynein 1 intermediate chain 2

3

2

High-throughput

0.656

High

995290

GOGA2
Golgin subfamily A member 2

3

0

High-throughput

0.652

High

1127201

MTUS2
Microtubule-associated tumor suppressor candidate 2

2

1

High-throughput

0.640

High

126721

DCTN6
Dynactin subunit 6

2

1

High-throughput

0.628

High

857245

CAZA1
F-actin-capping protein subunit alpha-1

2

1

High-throughput

0.611

High

1348640

MS18A
Protein Mis18-alpha

2

0

High-throughput

0.602

High

1356090

JIP3
C-Jun-amino-terminal kinase-interacting protein 3

2

0

High-throughput

0.602

High

1356089

DCTN4
Dynactin subunit 4

1

0

High-throughput

0.586

High

307228

KLHL2
Kelch-like protein 2

2

0

High-throughput

0.585

High

1028217

GPS2
G protein pathway suppressor 2

2

0

High-throughput

0.585

High

1051708

DYHC1
Cytoplasmic dynein 1 heavy chain 1

2

0

High-throughput

0.585

High

1077164

MARE1
Microtubule-associated protein RP/EB family member 1

2

0

High-throughput

0.585

High

1093053

CSPP1
Centrosome and spindle pole-associated protein 1

2

0

High-throughput

0.585

High

1025593

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

1

High-throughput

0.573

High

592567

RAB5A
Ras-related protein Rab-5A

2

1

High-throughput

0.571

High

229012

PRKN
E3 ubiquitin-protein ligase parkin

2

0

High-throughput

0.559

High

1242326

PNMA1
Paraneoplastic antigen Ma1

1

0

High-throughput

0.549

High

928514

DYL1
Dynein light chain 1, cytoplasmic

1

1

High-throughput

0.536

High

1312133

DCTN5
Dynactin subunit 5

1

2

High-throughput

0.536

High

529883

CFTR
Cystic fibrosis transmembrane conductance regulator

2

0

High-throughput

0.528

High

204522

ARK72
Aflatoxin B1 aldehyde reductase member 2

1

0

High-throughput

0.513

High

414106

GELS
Gelsolin

1

0

High-throughput

0.513

High

675246

CLIP1
CAP-Gly domain-containing linker protein 1

1

0

High-throughput

0.513

High

934018

TBB4B
Tubulin beta-4B chain

1

0

High-throughput

0.513

High

1016530

TWF1
Twinfilin-1

1

0

High-throughput

0.513

High

1074736

MED22
Mediator of RNA polymerase II transcription subunit 22

1

0

High-throughput

0.513

High

1190201

CLAP1
CLIP-associating protein 1

1

0

High-throughput

0.513

High

1203683

AROS
Active regulator of SIRT1

1

0

High-throughput

0.513

High

1229804

ABRA
Actin-binding Rho-activating protein

1

0

High-throughput

0.513

High

1273238

TNPO1
Transportin-1

1

0

High-throughput

0.513

High

1343015

RIC8A
Synembryn-A

1

0

High-throughput

0.513

High

1356092

DC1L1
Cytoplasmic dynein 1 light intermediate chain 1

1

0

High-throughput

0.513

High

792070

HD
Huntingtin

1

0

High-throughput

0.493

High

1342350

HM20A
High mobility group protein 20A

1

1

High-throughput

0.481

High

148119

DC1I1
Cytoplasmic dynein 1 intermediate chain 1

1

2

High-throughput

0.479

High

398310

PCCA
Propionyl-CoA carboxylase alpha chain, mitochondrial

1

2

High-throughput

0.479

High

398419

PCCB
Propionyl-CoA carboxylase beta chain, mitochondrial

1

1

High-throughput

0.479

High

631627

BRD2
Bromodomain-containing protein 2

1

1

High-throughput

0.479

High

845336

RAB7A
Ras-related protein Rab-7a

1

1

High-throughput

0.479

High

1024111

ACACA
Acetyl-CoA carboxylase 1

1

2

High-throughput

0.479

High

1082651

MK14
Mitogen-activated protein kinase 14

1

1

High-throughput

0.479

High

1123399

BRDT
Bromodomain testis-specific protein

1

1

High-throughput

0.479

High

1139463

ECM29
Proteasome adapter and scaffold protein ECM29

1

1

High-throughput

0.479

High

1172189

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

1233481

NIN
Ninein

1

1

High-throughput

0.479

High

1301298

MCCA
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial

1

2

High-throughput

0.479

High

1356091

NINL
Ninein-like protein

1

1

High-throughput

0.479

High

123073

MEN1
Menin

1

0

High-throughput

0.458

High

278678

DCTN3
Dynactin subunit 3

1

0

High-throughput

0.458

High

328993

TOP3B
DNA topoisomerase 3-beta-1

1

0

High-throughput

0.458

High

348186

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

575619

EGR1
Early growth response protein 1

1

0

High-throughput

0.458

High

591141

BTF3
Transcription factor BTF3

1

0

High-throughput

0.458

High

652554

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

676720

AL1B1
Aldehyde dehydrogenase X, mitochondrial

1

0

High-throughput

0.458

High

677050

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

0

High-throughput

0.458

High

713649

GLYM
Serine hydroxymethyltransferase, mitochondrial

1

0

High-throughput

0.458

High

749940

BRCA1
Breast cancer type 1 susceptibility protein

1

0

High-throughput

0.458

High

793037

LIS1
Platelet-activating factor acetylhydrolase IB subunit beta

1

0

High-throughput

0.458

High

806729

RL28
Large ribosomal subunit protein eL28

1

0

High-throughput

0.458

High

841484

BPL1
Biotin--protein ligase

1

0

High-throughput

0.458

High

877940

FOXA1
Hepatocyte nuclear factor 3-alpha

1

0

High-throughput

0.458

High

914441

RB11A
Ras-related protein Rab-11A

1

0

High-throughput

0.458

High

965171

ANK2
Ankyrin-2

1

0

Small-scale

0.458

High

984681

CALD1
Caldesmon

1

0

High-throughput

0.458

High

1029994

TIF1B
Transcription intermediary factor 1-beta

1

0

High-throughput

0.458

High

1049177

TRI14
Tripartite motif-containing protein 14

1

0

High-throughput

0.458

High

1187847

ZCCHV
Zinc finger CCCH-type antiviral protein 1

1

0

High-throughput

0.458

High

1216857

ARMC8
Armadillo repeat-containing protein 8

1

0

High-throughput

0.458

High

1267232

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

1267777

HS105
Heat shock protein 105 kDa

1

0

High-throughput

0.458

High

1269879

ESR2
Estrogen receptor beta

1

0

High-throughput

0.458

High

1270511

HDAC2
Histone deacetylase 2

1

0

High-throughput

0.458

High

1281876

FBX32
F-box only protein 32

1

0

High-throughput

0.458

High

1291733

BICD1
Protein bicaudal D homolog 1

1

0

High-throughput

0.458

High

1305139

DNJC7
DnaJ homolog subfamily C member 7

1

0

High-throughput

0.458

High

1331579

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

1332743

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1349751

RN181
E3 ubiquitin-protein ligase RNF181

1

0

High-throughput

0.458

High

1354789

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1355841

DS13B
Dual specificity protein phosphatase 13B

1

0

High-throughput

0.458

High

1168436

LMTK1
Serine/threonine-protein kinase LMTK1

1

1

High-throughput

0.437

High

1346985

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

1

High-throughput

0.437

High

1130705

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

89994

D6R9G5
Kelch like family member 2

1

1

High-throughput

0.407

High

596145

C4BPB
C4b-binding protein beta chain

3

0

High-throughput

0.347

High

1297744

MERB1
bMERB domain-containing protein 1

2

0

High-throughput

0.328

High

1326082

PDGFD
Platelet-derived growth factor D

2

0

High-throughput

0.328

High

1328788

DB127
Beta-defensin 127

2

0

High-throughput

0.328

High

727461

ATP7B
Copper-transporting ATPase 2

1

0

Small-scale

0.288

High

433098

QCR6
Cytochrome b-c1 complex subunit 6, mitochondrial

1

0

High-throughput

0.279

Low

1136042

N42L1
NEDD4-binding protein 2-like 1

1

0

High-throughput

0.279

Low

1246085

CC4L
C-C motif chemokine 4-like

1

0

High-throughput

0.279

Low

352304

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low

385687

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

1114388

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

1

0

High-throughput

0.249

Low

240244

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024