Protein: NUP88
Nuclear pore complex protein Nup88 (88 kDa nucleoporin) (Nucleoporin Nup88)

Gene: NUP88
Organism: Homo sapiens
Interactions: 132
UniProt ID: Q99567

Gene Ontology (top 5):
GO:0000055 - ribosomal large subunit export from nucleus
GO:0000056 - ribosomal small subunit export from nucleus
GO:0005635 - nuclear envelope
GO:0005643 - nuclear pore
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

916026

NUP98
Nuclear pore complex protein Nup98-Nup96

5

3

Small-scale

0.931

High

775592

NU214
Nuclear pore complex protein Nup214

9

2

Small-scale

0.752

High

789205

NUP62
Nuclear pore glycoprotein p62

5

3

High-throughput

0.716

High

173263

XPO1
Exportin-1

3

3

Small-scale

0.667

High

1405285

DD19A
ATP-dependent RNA helicase DDX19A

3

1

High-throughput

0.667

High

1405282

N62CL
Nucleoporin-62 C-terminal-like protein

2

2

High-throughput

0.628

High

1114097

CUL3
Cullin-3

2

1

High-throughput

0.611

High

1388899

SEH1
Nucleoporin SEH1

2

1

High-throughput

0.611

High

1405292

G3BP2
Ras GTPase-activating protein-binding protein 2

2

2

High-throughput

0.611

High

1405277

TRI62
E3 ubiquitin-protein ligase TRIM62

2

0

High-throughput

0.602

High

213642

VIP2
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2

2

1

High-throughput

0.584

High

1405287

TFP11
Tuftelin-interacting protein 11

2

0

High-throughput

0.580

High

242692

PRKN
E3 ubiquitin-protein ligase parkin

2

0

High-throughput

0.559

High

1339147

NUP35
Nucleoporin NUP35

2

0

High-throughput

0.559

High

1405288

NXF1
Nuclear RNA export factor 1

2

0

Small-scale

0.547

High

606153

DESM
Desmin

1

1

High-throughput

0.536

High

890389

NU153
Nuclear pore complex protein Nup153

1

4

High-throughput

0.536

High

965576

NTF2
Nuclear transport factor 2

1

2

High-throughput

0.536

High

1100976

G3BP1
Ras GTPase-activating protein-binding protein 1

1

2

High-throughput

0.536

High

1112966

CUL2
Cullin-2

1

1

High-throughput

0.536

High

1134692

NUMA1
Nuclear mitotic apparatus protein 1

1

1

High-throughput

0.536

High

571787

FPPS
Farnesyl pyrophosphate synthase

1

0

High-throughput

0.513

High

849397

RANG
Ran-specific GTPase-activating protein

1

0

High-throughput

0.513

High

945302

NU107
Nuclear pore complex protein Nup107

1

0

High-throughput

0.513

High

981660

RAN
GTP-binding nuclear protein Ran

1

0

High-throughput

0.513

High

1134347

IMB1
Importin subunit beta-1

1

0

High-throughput

0.513

High

1143008

PMVK
Phosphomevalonate kinase

1

0

High-throughput

0.513

High

1152219

MARE1
Microtubule-associated protein RP/EB family member 1

1

0

High-throughput

0.513

High

1291151

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

0

High-throughput

0.513

High

1405294

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

1

0

High-throughput

0.513

High

1397631

IMP1L
Mitochondrial inner membrane protease subunit 1

1

1

High-throughput

0.489

High

1403392

IMP2L
Mitochondrial inner membrane protease subunit 2

1

1

High-throughput

0.489

High

157769

CTRO
Citron Rho-interacting kinase

1

1

High-throughput

0.479

High

323550

TRI37
E3 ubiquitin-protein ligase TRIM37

1

1

High-throughput

0.479

High

372938

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.479

High

406548

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

984247

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

1

High-throughput

0.479

High

1007768

RAE1L
mRNA export factor RAE1

1

1

High-throughput

0.479

High

1143239

PLEC
Plectin

1

1

High-throughput

0.479

High

1191469

GRDN
Girdin

1

1

High-throughput

0.479

High

1199359

GLE1
mRNA export factor GLE1

1

2

High-throughput

0.479

High

1227328

A16L1
Autophagy-related protein 16-1

1

2

High-throughput

0.479

High

1329827

SIR6
NAD-dependent protein deacylase sirtuin-6

1

1

High-throughput

0.479

High

1338922

NUP43
Nucleoporin Nup43

1

1

High-throughput

0.479

High

1340789

COP1
E3 ubiquitin-protein ligase COP1

1

1

High-throughput

0.479

High

1350422

BICD2
Protein bicaudal D homolog 2

1

2

High-throughput

0.479

High

1352261

DCA11
DDB1- and CUL4-associated factor 11

1

1

High-throughput

0.479

High

1404717

RING2
E3 ubiquitin-protein ligase RING2

1

2

High-throughput

0.479

High

1405284

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

1

High-throughput

0.479

High

1405289

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

1405290

ANC2
Anaphase-promoting complex subunit 2

1

2

High-throughput

0.479

High

1405291

DD19B
ATP-dependent RNA helicase DDX19B

1

1

High-throughput

0.479

High

58745

PTPC1
Protein tyrosine phosphatase domain-containing protein 1

1

0

High-throughput

0.458

High

125579

LEG9
Galectin-9

1

0

High-throughput

0.458

High

129359

MEN1
Menin

1

0

High-throughput

0.458

High

194309

R113A
E3 ubiquitin-protein ligase RNF113A

1

0

High-throughput

0.458

High

213485

CTIF
CBP80/20-dependent translation initiation factor

1

0

High-throughput

0.458

High

246896

KDM1A
Lysine-specific histone demethylase 1A

1

0

High-throughput

0.458

High

248060

NUPR1
Nuclear protein 1

1

0

High-throughput

0.458

High

278948

PEX14
Peroxisomal membrane protein PEX14

1

0

High-throughput

0.458

High

291509

NU155
Nuclear pore complex protein Nup155

1

0

High-throughput

0.458

High

315924

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

338533

SC24B
Protein transport protein Sec24B

1

0

High-throughput

0.458

High

414476

P53
Cellular tumor antigen p53

1

0

Small-scale

0.458

High

437317

K2C8
Keratin, type II cytoskeletal 8

1

0

High-throughput

0.458

High

475671

K1C19
Keratin, type I cytoskeletal 19

1

0

High-throughput

0.458

High

483196

CLCA
Clathrin light chain A

1

0

High-throughput

0.458

High

589496

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

613441

VINC
Vinculin

1

0

High-throughput

0.458

High

696307

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

768978

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

831295

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

833015

ETV6
Transcription factor ETV6

1

0

High-throughput

0.458

High

851803

NKX21
Homeobox protein Nkx-2.1

1

0

High-throughput

0.458

High

878545

PAXI
Paxillin

1

0

High-throughput

0.458

High

920224

PLK1
Serine/threonine-protein kinase PLK1

1

0

High-throughput

0.458

High

965181

WDR5
WD repeat-containing protein 5

1

0

High-throughput

0.458

High

980196

H4
Histone H4

1

0

High-throughput

0.458

High

1026518

HSF1
Heat shock factor protein 1

1

0

High-throughput

0.458

High

1029366

SET
Protein SET

1

0

Small-scale

0.458

High

1100287

TIF1B
Transcription intermediary factor 1-beta

1

0

High-throughput

0.458

High

1107132

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

1110021

HDAC1
Histone deacetylase 1

1

0

High-throughput

0.458

High

1110702

DCTN2
Dynactin subunit 2

1

0

High-throughput

0.458

High

1115947

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

0

High-throughput

0.458

High

1137478

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.458

High

1140737

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

1161613

IF16
Gamma-interferon-inducible protein 16

1

0

High-throughput

0.458

High

1178328

CL16A
Protein CLEC16A

1

0

High-throughput

0.458

High

1178787

AAK1
AP2-associated protein kinase 1

1

0

High-throughput

0.458

High

1214561

ACBD5
Acyl-CoA-binding domain-containing protein 5

1

0

High-throughput

0.458

High

1252195

SYNE3
Nesprin-3

1

0

High-throughput

0.458

High

1278964

EMSY
BRCA2-interacting transcriptional repressor EMSY

1

0

High-throughput

0.458

High

1281592

SLN11
Schlafen family member 11

1

0

High-throughput

0.458

High

1289567

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

1322780

CNTRB
Centrobin

1

0

High-throughput

0.458

High

1334813

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.458

High

1367099

ESR2
Estrogen receptor beta

1

0

High-throughput

0.458

High

1380632

FBX32
F-box only protein 32

1

0

High-throughput

0.458

High

1384423

PF21A
PHD finger protein 21A

1

0

High-throughput

0.458

High

1405276

TBX5
T-box transcription factor TBX5

1

0

High-throughput

0.458

High

1405278

NUP85
Nuclear pore complex protein Nup85

1

0

High-throughput

0.458

High

1405286

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

328123

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

3

High-throughput

0.445

High

952302

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

3

High-throughput

0.445

High

1244269

VIP1
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1

1

1

High-throughput

0.445

High

1405280

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

3

High-throughput

0.445

High

1405281

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

3

High-throughput

0.445

High

1405283

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.437

High

664898

RAE1
Rab proteins geranylgeranyltransferase component A 1

1

0

High-throughput

0.426

High

756312

MCM7
DNA replication licensing factor MCM7

1

0

Small-scale

0.426

High

1066758

NCBP1
Nuclear cap-binding protein subunit 1

1

0

High-throughput

0.426

High

1119271

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

0

High-throughput

0.426

High

1209551

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

1348624

S7A14
Solute carrier family 7 member 14

1

0

High-throughput

0.426

High

1405293

DICER
Endoribonuclease Dicer

1

0

Small-scale

0.426

High

1405295

ST38L
Serine/threonine-protein kinase 38-like

1

0

High-throughput

0.426

High

1405296

COG6
Conserved oligomeric Golgi complex subunit 6

2

0

High-throughput

0.328

High

720690

AGTR1
Type-1 angiotensin II receptor

1

0

High-throughput

0.282

High

1241997

DJC24
DnaJ homolog subfamily C member 24

1

0

High-throughput

0.279

Low

412493

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

1249148

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

1250585

DPPA3
Developmental pluripotency-associated protein 3

1

0

High-throughput

0.249

Low

1255210

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1276692

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

1312896

PDZD9
PDZ domain-containing protein 9

1

0

High-throughput

0.249

Low

1324053

RHG24
Rho GTPase-activating protein 24

1

0

High-throughput

0.249

Low

1383657

VP33A
Vacuolar protein sorting-associated protein 33A

1

0

High-throughput

0.249

Low

1392332

BORC6
BLOC-1-related complex subunit 6

1

0

High-throughput

0.249

Low

1405279

CDHR2
Cadherin-related family member 2

1

0

High-throughput

0.249

Low

697363

CD82
CD82 antigen

1

0

High-throughput

0.238

Low

1309148

MISP
Mitotic interactor and substrate of PLK1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025