Protein: Q9HCK3
KIAA1569 protein

Gene: Q9HCK3, KIAA1569
Organism: Homo sapiens
Interactions: 176
UniProt ID: Q9HCK3

Gene Ontology (top 5):
GO:0051298 - centrosome duplication
GO:0071539 - protein localization to centrosome
GO:0090222 - centrosome-templated microtubule nucleation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

170362

AURKA
Aurora kinase A

9

5

High-throughput

0.745

High

1439169

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

3

1

Small-scale

0.585

High

1439185

CARD8
Caspase recruitment domain-containing protein 8

3

1

High-throughput

0.585

High

1326351

NIN
Ninein

2

1

High-throughput

0.584

High

324218

CE152
Centrosomal protein of 152 kDa

2

0

High-throughput

0.559

High

1143543

PCM1
Pericentriolar material 1 protein

2

0

High-throughput

0.559

High

1248202

SAS6
Spindle assembly abnormal protein 6 homolog

2

0

High-throughput

0.559

High

323574

TRI37
E3 ubiquitin-protein ligase TRIM37

2

1

High-throughput

0.549

High

136139

PLK4
Serine/threonine-protein kinase PLK4

2

5

Small-scale

0.533

High

340243

PCNT
Pericentrin

2

1

High-throughput

0.533

High

349251

LATS1
Serine/threonine-protein kinase LATS1

2

1

High-throughput

0.533

High

1391782

AURKB
Aurora kinase B

2

5

High-throughput

0.533

High

1396434

EGLN2
Prolyl hydroxylase EGLN2

2

1

Small-scale

0.533

High

1398364

CEP63
Centrosomal protein of 63 kDa

2

2

High-throughput

0.533

High

1406424

FEZ1
Fasciculation and elongation protein zeta-1

2

1

High-throughput

0.533

High

1430856

SIL1
Nucleotide exchange factor SIL1

2

1

High-throughput

0.533

High

1435556

DCTP1
dCTP pyrophosphatase 1

2

1

High-throughput

0.533

High

1439172

HOME3
Homer protein homolog 3

2

2

High-throughput

0.533

High

1439186

NINL
Ninein-like protein

2

1

High-throughput

0.533

High

1193480

CCD14
Coiled-coil domain-containing protein 14

1

1

High-throughput

0.479

High

1217508

CE350
Centrosome-associated protein 350

1

1

High-throughput

0.479

High

1291583

HOOK3
Protein Hook homolog 3

1

1

High-throughput

0.479

High

1228478

FTM
Protein fantom

1

1

High-throughput

0.470

High

164102

NDC80
Kinetochore protein NDC80 homolog

1

0

High-throughput

0.458

High

1110729

DCTN2
Dynactin subunit 2

1

0

High-throughput

0.458

High

1149379

STIL
SCL-interrupting locus protein

1

0

High-throughput

0.458

High

1439183

CP131
Centrosomal protein of 131 kDa

1

0

High-throughput

0.458

High

967987

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

1

Small-scale

0.457

High

122854

KIF2A
Kinesin-like protein KIF2A

1

2

High-throughput

0.437

High

252487

DIAP1
Protein diaphanous homolog 1

1

1

High-throughput

0.437

High

284354

GEMI
Geminin

1

1

High-throughput

0.437

High

391472

FRIL
Ferritin light chain

1

1

High-throughput

0.437

High

437011

K1C18
Keratin, type I cytoskeletal 18

1

1

High-throughput

0.437

High

466060

ANXA6
Annexin A6

1

1

High-throughput

0.437

High

541698

FGFR1
Fibroblast growth factor receptor 1

1

3

High-throughput

0.437

High

641264

FGFR2
Fibroblast growth factor receptor 2

1

3

High-throughput

0.437

High

648686

FGFR4
Fibroblast growth factor receptor 4

1

3

High-throughput

0.437

High

650427

FGFR3
Fibroblast growth factor receptor 3

1

3

High-throughput

0.437

High

682620

S100P
Protein S100-P

1

4

High-throughput

0.437

High

691454

1433T
14-3-3 protein theta

1

5

High-throughput

0.437

High

703069

DPOD1
DNA polymerase delta catalytic subunit

1

1

High-throughput

0.437

High

730265

1433B
14-3-3 protein beta/alpha

1

5

High-throughput

0.437

High

730901

1433S
14-3-3 protein sigma

1

5

High-throughput

0.437

High

875792

PRC2A
Protein PRRC2A

1

2

High-throughput

0.437

High

891320

GSK3A
Glycogen synthase kinase-3 alpha

1

1

High-throughput

0.437

High

891804

GSK3B
Glycogen synthase kinase-3 beta

1

1

High-throughput

0.437

High

896639

VASP
Vasodilator-stimulated phosphoprotein

1

2

High-throughput

0.437

High

936453

AFAD
Afadin

1

1

High-throughput

0.437

High

954992

S10AA
Protein S100-A10

1

4

High-throughput

0.437

High

966900

1433G
14-3-3 protein gamma

1

5

High-throughput

0.437

High

990763

1433Z
14-3-3 protein zeta/delta

1

5

High-throughput

0.437

High

1049809

1433F
14-3-3 protein eta

1

5

High-throughput

0.437

High

1053435

DEUP1
Deuterosome assembly protein 1

1

2

High-throughput

0.437

High

1124920

FLOT2
Flotillin-2

1

1

High-throughput

0.437

High

1125233

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

1

High-throughput

0.437

High

1134394

IMB1
Importin subunit beta-1

1

1

High-throughput

0.437

High

1135386

SLMAP
Sarcolemmal membrane-associated protein

1

1

High-throughput

0.437

High

1155794

EZH2
Histone-lysine N-methyltransferase EZH2

1

1

High-throughput

0.437

High

1156219

ZYX
Zyxin

1

1

High-throughput

0.437

High

1194391

LARP7
La-related protein 7

1

2

High-throughput

0.437

High

1206550

PRC2B
Protein PRRC2B

1

2

High-throughput

0.437

High

1212620

HECD3
E3 ubiquitin-protein ligase HECTD3

1

1

High-throughput

0.437

High

1227501

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.437

High

1233500

LTOR1
Ragulator complex protein LAMTOR1

1

1

High-throughput

0.437

High

1241964

FBX42
F-box only protein 42

1

1

High-throughput

0.437

High

1244488

ULK3
Serine/threonine-protein kinase ULK3

1

2

High-throughput

0.437

High

1286590

SDCG8
Serologically defined colon cancer antigen 8

1

1

Small-scale

0.437

High

1312938

RB12B
RNA-binding protein 12B

1

1

Small-scale

0.437

High

1327795

SH2D3
SH2 domain-containing protein 3C

1

1

High-throughput

0.437

High

1333171

KDM1B
Lysine-specific histone demethylase 2

1

1

High-throughput

0.437

High

1336851

TNR6A
Trinucleotide repeat-containing gene 6A protein

1

2

High-throughput

0.437

High

1350456

BICD2
Protein bicaudal D homolog 2

1

1

High-throughput

0.437

High

1391183

BICD1
Protein bicaudal D homolog 1

1

1

High-throughput

0.437

High

1394842

LOXL4
Lysyl oxidase homolog 4

1

1

High-throughput

0.437

High

1405140

DNJC2
DnaJ homolog subfamily C member 2

1

1

High-throughput

0.437

High

1405680

NECD
Necdin

1

1

High-throughput

0.437

High

1411316

LZTS2
Leucine zipper putative tumor suppressor 2

1

2

High-throughput

0.437

High

1417885

DUS16
Dual specificity protein phosphatase 16

1

1

High-throughput

0.437

High

1434405

RNF41
E3 ubiquitin-protein ligase NRDP1

1

2

High-throughput

0.437

High

1434683

RABE2
Rab GTPase-binding effector protein 2

1

1

High-throughput

0.437

High

1435316

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.437

High

1439098

TNR6C
Trinucleotide repeat-containing gene 6C protein

1

3

High-throughput

0.437

High

1439171

LATS2
Serine/threonine-protein kinase LATS2

1

1

High-throughput

0.437

High

1439176

TBK1
Serine/threonine-protein kinase TBK1

1

1

High-throughput

0.437

High

1439178

HOOK1
Protein Hook homolog 1

1

1

High-throughput

0.437

High

1439179

ANC2
Anaphase-promoting complex subunit 2

1

1

High-throughput

0.437

High

1439184

TNR6B
Trinucleotide repeat-containing gene 6B protein

1

2

High-throughput

0.437

High

1439188

PCDBF
Protocadherin beta-15

1

1

High-throughput

0.437

High

1439190

MAGD1
Melanoma-associated antigen D1

1

1

High-throughput

0.437

High

1241594

CEP85
Centrosomal protein of 85 kDa

3

0

Small-scale

0.334

High

290163

OFD1
Centriole and centriolar satellite protein OFD1

2

0

High-throughput

0.305

High

1226281

CP135
Centrosomal protein of 135 kDa

2

0

High-throughput

0.305

High

1340673

NEDD1
Protein NEDD1

2

0

Small-scale

0.305

High

1350186

ALMS1
Centrosome-associated protein ALMS1

2

0

Small-scale

0.305

High

1402908

CK5P2
CDK5 regulatory subunit-associated protein 2

2

0

High-throughput

0.305

High

1438720

CPAP
Centrosomal P4.1-associated protein

2

0

High-throughput

0.305

High

508669

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

High-throughput

0.261

Low

1349698

CIP2A
Protein CIP2A

1

0

Small-scale

0.251

Low

122557

ADAS
Alkyldihydroxyacetonephosphate synthase, peroxisomal

1

0

High-throughput

0.249

Low

124653

EYA2
Protein phosphatase EYA2

1

0

High-throughput

0.249

Low

176554

GRRE1
Granule associated Rac and RHOG effector protein 1

1

0

High-throughput

0.249

Low

177311

ANR28
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A

1

0

High-throughput

0.249

Low

208570

PJA2
E3 ubiquitin-protein ligase Praja-2

1

0

Small-scale

0.249

Low

239394

BNI3L
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like

1

0

Small-scale

0.249

Low

242997

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.249

Low

246146

KIF1B
Kinesin-like protein KIF1B

1

0

High-throughput

0.249

Low

291549

NU155
Nuclear pore complex protein Nup155

1

0

High-throughput

0.249

Low

414665

P53
Cellular tumor antigen p53

1

0

High-throughput

0.249

Low

437353

K2C8
Keratin, type II cytoskeletal 8

1

0

High-throughput

0.249

Low

459759

PROF1
Profilin-1

1

0

High-throughput

0.249

Low

475694

K1C19
Keratin, type I cytoskeletal 19

1

0

High-throughput

0.249

Low

483223

CLCA
Clathrin light chain A

1

0

High-throughput

0.249

Low

589749

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

613468

VINC
Vinculin

1

0

High-throughput

0.249

Low

688322

TTP
mRNA decay activator protein ZFP36

1

0

High-throughput

0.249

Low

692139

MARK3
MAP/microtubule affinity-regulating kinase 3

1

0

High-throughput

0.249

Low

696568

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

769236

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

833027

ETV6
Transcription factor ETV6

1

0

High-throughput

0.249

Low

878564

PAXI
Paxillin

1

0

High-throughput

0.249

Low

948172

DJB13
DnaJ homolog subfamily B member 13

1

0

High-throughput

0.249

Low

958200

ARP3
Actin-related protein 3

1

0

High-throughput

0.249

Low

989126

AP2B1
AP-2 complex subunit beta

1

0

High-throughput

0.249

Low

1071192

ARL16
ADP-ribosylation factor-like protein 16

1

0

High-throughput

0.249

Low

1101906

SKP2
S-phase kinase-associated protein 2

1

0

Small-scale

0.249

Low

1114355

CUL3
Cullin-3

1

0

High-throughput

0.249

Low

1156599

CCDC6
Coiled-coil domain-containing protein 6

1

0

High-throughput

0.249

Low

1178814

KIZ
Centrosomal protein kizuna

1

0

High-throughput

0.249

Low

1197094

AMOT
Angiomotin

1

0

High-throughput

0.249

Low

1203265

ODFP2
Outer dense fiber protein 2

1

0

High-throughput

0.249

Low

1208583

SMAG2
Protein Smaug homolog 2

1

0

High-throughput

0.249

Low

1214572

ACBD5
Acyl-CoA-binding domain-containing protein 5

1

0

High-throughput

0.249

Low

1218070

CBPC6
Cytosolic carboxypeptidase 6

1

0

Small-scale

0.249

Low

1219895

OBI1
ORC ubiquitin ligase 1

1

0

High-throughput

0.249

Low

1252242

SYNE3
Nesprin-3

1

0

High-throughput

0.249

Low

1256599

CE128
Centrosomal protein of 128 kDa

1

0

High-throughput

0.249

Low

1280921

CNTRL
Centriolin

1

0

High-throughput

0.249

Low

1287133

PATL1
Protein PAT1 homolog 1

1

0

High-throughput

0.249

Low

1288983

EST1A
Telomerase-binding protein EST1A

1

0

High-throughput

0.249

Low

1293670

DYR2
Dihydrofolate reductase 2, mitochondrial

1

0

High-throughput

0.249

Low

1316462

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.249

Low

1322794

CNTRB
Centrobin

1

0

High-throughput

0.249

Low

1331564

CE120
Centrosomal protein of 120 kDa

1

0

High-throughput

0.249

Low

1332513

POC5
Centrosomal protein POC5

1

0

High-throughput

0.249

Low

1333018

F184A
Protein FAM184A

1

0

High-throughput

0.249

Low

1336216

RN214
RING finger protein 214

1

0

High-throughput

0.249

Low

1353144

FBF1
Fas-binding factor 1

1

0

High-throughput

0.249

Low

1365365

CNOT9
CCR4-NOT transcription complex subunit 9

1

0

High-throughput

0.249

Low

1368957

GOGA1
Golgin subfamily A member 1

1

0

High-throughput

0.249

Low

1385699

ENTR1
Endosome-associated-trafficking regulator 1

1

0

High-throughput

0.249

Low

1387845

ZBT10
Zinc finger and BTB domain-containing protein 10

1

0

Small-scale

0.249

Low

1390410

EDC3
Enhancer of mRNA-decapping protein 3

1

0

High-throughput

0.249

Low

1392348

BORC6
BLOC-1-related complex subunit 6

1

0

High-throughput

0.249

Low

1397042

CNO6L
CCR4-NOT transcription complex subunit 6-like

1

0

High-throughput

0.249

Low

1397114

CEP19
Centrosomal protein of 19 kDa

1

0

High-throughput

0.249

Low

1403077

CEP89
Centrosomal protein of 89 kDa

1

0

High-throughput

0.249

Low

1417929

K1671
Uncharacterized protein KIAA1671

1

0

High-throughput

0.249

Low

1419420

RHBT2
Rho-related BTB domain-containing protein 2

1

0

High-throughput

0.249

Low

1421053

CE295
Centrosomal protein of 295 kDa

1

0

High-throughput

0.249

Low

1429230

MKRN2
E3 ubiquitin-protein ligase makorin-2

1

0

High-throughput

0.249

Low

1435684

TDRD3
Tudor domain-containing protein 3

1

0

High-throughput

0.249

Low

1437139

UBP42
Ubiquitin carboxyl-terminal hydrolase 42

1

0

High-throughput

0.249

Low

1437952

CYBP
Calcyclin-binding protein

1

0

High-throughput

0.249

Low

1439167

DLRB1
Dynein light chain roadblock-type 1

1

0

High-throughput

0.249

Low

1439168

DCP1A
mRNA-decapping enzyme 1A

1

0

High-throughput

0.249

Low

1439170

4ET
Eukaryotic translation initiation factor 4E transporter

1

0

High-throughput

0.249

Low

1439173

F120C
Constitutive coactivator of PPAR-gamma-like protein 2

1

0

High-throughput

0.249

Low

1439174

CNOT2
CCR4-NOT transcription complex subunit 2

1

0

High-throughput

0.249

Low

1439175

SEP10
Septin-10

1

0

High-throughput

0.249

Low

1439177

XPO7
Exportin-7

1

0

High-throughput

0.249

Low

1439180

MYO6
Unconventional myosin-VI

1

0

High-throughput

0.249

Low

1439181

SPAT2
Spermatogenesis-associated protein 2

1

0

High-throughput

0.249

Low

1439182

PRP19
Pre-mRNA-processing factor 19

1

0

High-throughput

0.249

Low

1439187

R3HD2
R3H domain-containing protein 2

1

0

High-throughput

0.249

Low

1439189

HEY1
Hairy/enhancer-of-split related with YRPW motif protein 1

1

0

Small-scale

0.249

Low

373204

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025