Protein: NOP16
Nucleolar protein 16

Gene: NOP16
Organism: Saccharomyces cerevisiae S288C
Interactions: 94
UniProt ID: P40007

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005730 - nucleolus
GO:0006364 - rRNA processing
GO:0030687 - preribosome, large subunit precursor
GO:0042273 - ribosomal large subunit biogenesis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

682289

SPB4
ATP-dependent rRNA helicase SPB4

3

2

High-throughput

0.827

High

816789

HAS1
ATP-dependent RNA helicase HAS1

3

2

High-throughput

0.827

High

816796

ERB1
Ribosome biogenesis protein ERB1

2

0

High-throughput

0.748

High

816780

PESC
Pescadillo homolog

6

0

Small-scale

0.695

High

816814

MAK21
Ribosome biogenesis protein MAK21

4

2

High-throughput

0.680

High

814325

NOC2
Nucleolar complex protein 2

5

0

Small-scale

0.672

High

816806

BRX1
Ribosome biogenesis protein BRX1

3

3

High-throughput

0.658

High

782341

RPF2
Ribosome biogenesis protein RPF2

4

0

Small-scale

0.653

High

791060

NOP4
Nucleolar protein 4

4

0

Small-scale

0.651

High

816787

NOG1
Nucleolar GTP-binding protein 1

4

0

Small-scale

0.648

High

816816

IF6
Eukaryotic translation initiation factor 6

3

0

Small-scale

0.628

High

780268

EBP2
rRNA-processing protein EBP2

3

0

High-throughput

0.618

High

816776

LOC1
60S ribosomal subunit assembly/export protein LOC1

3

0

High-throughput

0.618

High

816769

NUG1
Nuclear GTP-binding protein NUG1

3

0

High-throughput

0.613

High

816778

NSA1
Ribosome biogenesis protein NSA1

3

0

Small-scale

0.613

High

816811

YTM1
Ribosome biogenesis protein YTM1

3

0

Small-scale

0.613

High

816815

DBP10
ATP-dependent RNA helicase DBP10

3

0

High-throughput

0.613

High

816774

NOP2
25S rRNA

2

1

Small-scale

0.584

High

633165

MAK11
Protein MAK11

2

0

Small-scale

0.559

High

763076

RRP1
Ribosomal RNA-processing protein 1

2

0

Small-scale

0.559

High

803867

CIC1
Proteasome-interacting protein CIC1

2

0

High-throughput

0.559

High

804614

SSF1
Ribosome biogenesis protein SSF1

2

0

Small-scale

0.559

High

816773

RLP7
Ribosome biogenesis protein RLP7

2

0

High-throughput

0.559

High

816782

NOP15
Ribosome biogenesis protein 15

2

0

High-throughput

0.559

High

816790

RRP17
Ribosomal RNA-processing protein 17

2

0

High-throughput

0.559

High

816797

RRP5
rRNA biogenesis protein RRP5

2

0

High-throughput

0.559

High

816801

RRP15
Ribosomal RNA-processing protein 15

2

0

Small-scale

0.559

High

816804

RLP24
Ribosome biogenesis protein RLP24

2

0

Small-scale

0.559

High

805049

RPF1
Ribosome production factor 1

2

0

High-throughput

0.547

High

816793

PUF6
Pumilio homology domain family member 6

2

0

Small-scale

0.547

High

816809

RRS1
Regulator of ribosome biosynthesis

2

0

High-throughput

0.547

High

816777

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.517

High

448174

HAP2
Transcriptional activator HAP2

1

0

High-throughput

0.513

High

721967

XPO1
Exportin-1

1

0

High-throughput

0.513

High

746629

DRS1
ATP-dependent RNA helicase DRS1

1

1

High-throughput

0.479

High

807077

FKBP3
Peptidyl-prolyl cis-trans isomerase

1

1

High-throughput

0.479

High

816784

RCM1
25S rRNA

1

1

High-throughput

0.479

High

816798

FKBP4
FK506-binding protein 4

1

1

High-throughput

0.479

High

816800

DBP9
ATP-dependent RNA helicase DBP9

1

1

High-throughput

0.479

High

816802

NOC4
Nucleolar complex protein 4

1

2

High-throughput

0.479

High

816803

NOC3
Nucleolar complex-associated protein 3

1

1

High-throughput

0.479

High

816805

NOP12
Nucleolar protein 12

1

1

High-throughput

0.479

High

149786

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.458

High

383311

RL28
Large ribosomal subunit protein uL15

1

0

High-throughput

0.458

High

410156

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.458

High

433663

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.458

High

435988

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

441929

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

448310

PDE2
3',5'-cyclic-nucleotide phosphodiesterase 2

1

0

High-throughput

0.458

High

512461

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.458

High

534112

MAK16
Protein MAK16

1

0

High-throughput

0.458

High

594384

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

674648

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

677204

SPB1
27S pre-rRNA

1

0

High-throughput

0.458

High

677411

KRR1
KRR1 small subunit processome component

1

0

High-throughput

0.458

High

689480

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

707191

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

734996

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

750085

MRT4
Ribosome assembly factor MRT4

1

0

High-throughput

0.458

High

780679

RRP14
Ribosomal RNA-processing protein 14

1

0

High-throughput

0.458

High

792068

GBLP
Small ribosomal subunit protein RACK1

1

0

High-throughput

0.458

High

795819

YBC8
UPF0642 protein YBL028C

1

0

High-throughput

0.458

High

798225

ENP1
Essential nuclear protein 1

1

0

High-throughput

0.458

High

816770

NSA2
Ribosome biogenesis protein NSA2

1

0

High-throughput

0.458

High

816772

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

816775

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.458

High

816781

NOP13
Nucleolar protein 13

1

0

High-throughput

0.458

High

816783

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.458

High

816785

ORC1
Origin recognition complex subunit 1

1

0

High-throughput

0.458

High

816788

TOM1
E3 ubiquitin-protein ligase TOM1

1

0

High-throughput

0.458

High

816791

RRB1
Ribosome assembly protein RRB1

1

0

High-throughput

0.458

High

816794

UTP14
U3 small nucleolar RNA-associated protein 14

1

0

High-throughput

0.458

High

816799

JIP5
WD repeat-containing protein JIP5

1

0

High-throughput

0.458

High

816807

SGO1
Shugoshin

1

0

High-throughput

0.458

High

816810

NIP7
60S ribosome subunit biogenesis protein NIP7

1

0

High-throughput

0.458

High

816812

NOP53
Ribosome biogenesis protein NOP53

1

0

High-throughput

0.458

High

816813

YP150
Putative serine/threonine-protein kinase YPL150W

1

0

High-throughput

0.261

Low

383721

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

455084

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.249

Low

503065

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

504233

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.249

Low

513028

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

514656

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.249

Low

747388

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.249

Low

753392

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.249

Low

778350

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.249

Low

802197

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.249

Low

812327

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

816771

MLP2
Protein MLP2

1

0

High-throughput

0.249

Low

816779

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.249

Low

816786

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.249

Low

816792

VMS1
tRNA endonuclease VMS1

1

0

High-throughput

0.249

Low

816795

POB3
FACT complex subunit POB3

1

0

High-throughput

0.249

Low

816808

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025