Protein: TYOBP
TYRO protein tyrosine kinase-binding protein (DNAX-activation protein 12) (Killer-activating receptor-associated protein) (KAR-associated protein)

Gene: TYOBP, TYROBP
Organism: Homo sapiens
Interactions: 89
UniProt ID: O43914

Gene Ontology (top 5):
GO:0002222 - stimulatory killer cell immunoglobulin-like receptor signaling pathway
GO:0002223 - stimulatory C-type lectin receptor signaling pathway
GO:0002274 - myeloid leukocyte activation
GO:0002282 - microglial cell activation involved in immune response
GO:0002283 - neutrophil activation involved in immune response

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

217292

NCTR2
Natural cytotoxicity triggering receptor 2

2

9

Small-scale

0.601

High

217362

TREM1
Triggering receptor expressed on myeloid cells 1

2

9

Small-scale

0.601

High

217299

KSYK
Tyrosine-protein kinase SYK

2

1

Small-scale

0.595

High

122302

SIRB1
Signal-regulatory protein beta-1

2

0

Small-scale

0.585

High

217296

NKG2C
NKG2-C type II integral membrane protein

2

3

Small-scale

0.584

High

217301

KI2S2
Killer cell immunoglobulin-like receptor 2DS2

2

3

Small-scale

0.584

High

217366

TREM2
Triggering receptor expressed on myeloid cells 2

2

0

Small-scale

0.583

High

217338

TM86A
Lysoplasmalogenase TMEM86A

2

0

High-throughput

0.580

High

217288

TYOBP
TYRO protein tyrosine kinase-binding protein

1

0

Small-scale

0.554

High

217344

S35B4
Nucleotide sugar transporter SLC35B4

2

1

High-throughput

0.553

High

217293

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

1

High-throughput

0.536

High

217294

AT2B4
Plasma membrane calcium-transporting ATPase 4

1

1

High-throughput

0.536

High

217302

DYN2
Dynamin-2

1

2

High-throughput

0.536

High

217305

AT12A
Potassium-transporting ATPase alpha chain 2

1

1

High-throughput

0.536

High

217309

DYN1
Dynamin-1

1

2

High-throughput

0.536

High

217341

S35B2
Adenosine 3'-phospho 5'-phosphosulfate transporter 1

1

1

High-throughput

0.536

High

217359

AT133
Polyamine-transporting ATPase 13A3

1

4

High-throughput

0.536

High

217360

AT131
Endoplasmic reticulum transmembrane helix translocase

1

3

High-throughput

0.536

High

217369

DYN3
Dynamin-3

1

2

High-throughput

0.536

High

217316

KI2S5
Killer cell immunoglobulin-like receptor 2DS5

1

3

Small-scale

0.534

High

183344

KCNN4
Intermediate conductance calcium-activated potassium channel protein 4

1

0

High-throughput

0.513

High

217289

HIP1R
Huntingtin-interacting protein 1-related protein

1

0

High-throughput

0.513

High

217291

WFS1
Wolframin

1

0

High-throughput

0.513

High

217295

ITB8
Integrin beta-8

1

0

High-throughput

0.513

High

217303

LRBA
Lipopolysaccharide-responsive and beige-like anchor protein

1

0

High-throughput

0.513

High

217304

CCHL
Holocytochrome c-type synthase

1

0

High-throughput

0.513

High

217306

GEMI4
Gem-associated protein 4

1

0

High-throughput

0.513

High

217307

DAD1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1

1

0

High-throughput

0.513

High

217308

TAP2
Antigen peptide transporter 2

1

0

High-throughput

0.513

High

217312

CD47
Leukocyte surface antigen CD47

1

0

High-throughput

0.513

High

217317

PDS5A
Sister chromatid cohesion protein PDS5 homolog A

1

0

High-throughput

0.513

High

217318

ALG11
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase

1

0

High-throughput

0.513

High

217320

PAR14
Protein mono-ADP-ribosyltransferase PARP14

1

0

High-throughput

0.513

High

217323

ODR4
Protein odr-4 homolog

1

0

High-throughput

0.513

High

217324

TBC9B
TBC1 domain family member 9B

1

0

High-throughput

0.513

High

217326

TTI2
TELO2-interacting protein 2

1

0

High-throughput

0.513

High

217327

CNNM4
Metal transporter CNNM4

1

0

High-throughput

0.513

High

217330

UBR3
E3 ubiquitin-protein ligase UBR3

1

0

High-throughput

0.513

High

217331

DYM
Dymeclin

1

0

High-throughput

0.513

High

217332

ERMP1
Endoplasmic reticulum metallopeptidase 1

1

0

High-throughput

0.513

High

217335

ZDH17
Palmitoyltransferase ZDHHC17

1

0

High-throughput

0.513

High

217336

HDBP1
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1

1

0

High-throughput

0.513

High

217337

LRC8A
Volume-regulated anion channel subunit LRRC8A

1

0

High-throughput

0.513

High

217340

VANG1
Vang-like protein 1

1

0

High-throughput

0.513

High

217343

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

0

High-throughput

0.513

High

217345

F241B
Protein FAM241B

1

0

High-throughput

0.513

High

217346

CYFP2
Cytoplasmic FMR1-interacting protein 2

1

0

High-throughput

0.513

High

217347

RN185
E3 ubiquitin-protein ligase RNF185

1

0

High-throughput

0.513

High

217349

PANX1
Pannexin-1

1

0

High-throughput

0.513

High

217350

YMEL1
ATP-dependent zinc metalloprotease YME1L1

1

0

High-throughput

0.513

High

217351

SEC62
Translocation protein SEC62

1

0

High-throughput

0.513

High

217352

SMAD5
Mothers against decapentaplegic homolog 5

1

0

High-throughput

0.513

High

217353

CIB1
Calcium and integrin-binding protein 1

1

0

High-throughput

0.513

High

217355

MAGT1
Magnesium transporter protein 1

1

0

High-throughput

0.513

High

217365

F118A
Protein FAM118A

1

0

High-throughput

0.513

High

217357

TMX4
Thioredoxin-related transmembrane protein 4

1

1

High-throughput

0.489

High

217358

TMX1
Thioredoxin-related transmembrane protein 1

1

1

High-throughput

0.489

High

66493

CLM7
CMRF35-like molecule 7

1

9

Small-scale

0.479

High

177590

SIGL5
Sialic acid-binding Ig-like lectin 5

1

1

Small-scale

0.479

High

217300

KI2L3
Killer cell immunoglobulin-like receptor 2DL3

1

3

Small-scale

0.479

High

217311

CLM6
CMRF35-like molecule 6

1

9

Small-scale

0.479

High

217313

SIG14
Sialic acid-binding Ig-like lectin 14

1

1

Small-scale

0.479

High

217314

KLRD1
Natural killer cells antigen CD94

1

3

Small-scale

0.479

High

217315

KI2S3
Killer cell immunoglobulin-like receptor 2DS3

1

3

Small-scale

0.479

High

217328

CLM5
CMRF35-like molecule 5

1

10

Small-scale

0.479

High

3044

CD3CH
Protein CD300H

1

9

Small-scale

0.445

High

217339

S15A4
Solute carrier family 15 member 4

1

0

Small-scale

0.426

High

217298

ZAP70
Tyrosine-protein kinase ZAP-70

1

1

Small-scale

0.408

High

217290

CDC45
Cell division control protein 45 homolog

1

0

High-throughput

0.279

Low

217297

MTHR
Methylenetetrahydrofolate reductase

1

0

High-throughput

0.279

Low

217310

CP24A
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial

1

0

High-throughput

0.279

Low

217319

HSDL1
Inactive hydroxysteroid dehydrogenase-like protein 1

1

0

High-throughput

0.279

Low

217321

MBRL
Membralin

1

0

High-throughput

0.279

Low

217322

GPAT3
Glycerol-3-phosphate acyltransferase 3

1

0

High-throughput

0.279

Low

217325

HEAT6
HEAT repeat-containing protein 6

1

0

High-throughput

0.279

Low

217329

THADA
tRNA

1

0

High-throughput

0.279

Low

217333

NOP9
Nucleolar protein 9

1

0

High-throughput

0.279

Low

217334

RETR3
Reticulophagy regulator 3

1

0

High-throughput

0.279

Low

217342

BRI3B
BRI3-binding protein

1

0

High-throughput

0.279

Low

217348

INT4
Integrator complex subunit 4

1

0

High-throughput

0.279

Low

217354

PGAP4
Post-GPI attachment to proteins factor 4

1

0

High-throughput

0.279

Low

217356

TSYL1
Testis-specific Y-encoded-like protein 1

1

0

High-throughput

0.279

Low

217361

MRS2
Magnesium transporter MRS2 homolog, mitochondrial

1

0

High-throughput

0.279

Low

217363

PYRG2
CTP synthase 2

1

0

High-throughput

0.279

Low

217364

UFSP2
Ufm1-specific protease 2

1

0

High-throughput

0.279

Low

217367

COPG2
Coatomer subunit gamma-2

1

0

High-throughput

0.279

Low

217368

EXTL2
Exostosin-like 2

1

0

High-throughput

0.279

Low

217370

TNPO3
Transportin-3

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024