Protein: OVOL2
Transcription factor Ovo-like 2 (hOvo2) (Zinc finger protein 339)

Gene: OVOL2
Organism: Homo sapiens
Interactions: 124
UniProt ID: Q9BRP0

Gene Ontology (top 5):
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1353589

ZN526
Zinc finger protein 526

2

19

High-throughput

0.783

High

625587

CSK22
Casein kinase II subunit alpha'

1

7

High-throughput

0.691

High

997974

CSK21
Casein kinase II subunit alpha

1

8

High-throughput

0.691

High

1028366

MDM2
E3 ubiquitin-protein ligase Mdm2

2

2

Small-scale

0.639

High

897955

CDK9
Cyclin-dependent kinase 9

1

3

Small-scale

0.618

High

1110549

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

1

1

Small-scale

0.618

High

1110036

HDAC1
Histone deacetylase 1

2

13

Small-scale

0.584

High

278418

NCOR1
Nuclear receptor corepressor 1

1

13

Small-scale

0.561

High

487689

PARP1
Poly [ADP-ribose] polymerase 1

1

3

Small-scale

0.561

High

1045706

TF65
Transcription factor p65

1

5

Small-scale

0.561

High

164632

TNPO2
Transportin-2

1

20

High-throughput

0.536

High

207871

ZZEF1
Zinc finger ZZ-type and EF-hand domain-containing protein 1

1

11

High-throughput

0.536

High

274229

ANR17
Ankyrin repeat domain-containing protein 17

1

3

High-throughput

0.536

High

995224

CSK2B
Casein kinase II subunit beta

1

2

High-throughput

0.536

High

1370996

TNPO1
Transportin-1

1

20

High-throughput

0.536

High

1371644

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

7

High-throughput

0.536

High

1411494

LHPP
Phospholysine phosphohistidine inorganic pyrophosphate phosphatase

1

1

High-throughput

0.536

High

1411500

HM20B
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related

1

4

High-throughput

0.536

High

1411501

RCOR3
REST corepressor 3

1

10

High-throughput

0.536

High

1411504

RCOR1
REST corepressor 1

1

10

High-throughput

0.536

High

1242039

SCYL2
SCY1-like protein 2

1

0

Small-scale

0.517

High

881737

FNTB
Protein farnesyltransferase subunit beta

1

0

High-throughput

0.513

High

1359443

LMO7
LIM domain only protein 7

1

0

High-throughput

0.513

High

1411503

CBPA4
Carboxypeptidase A4

1

0

High-throughput

0.513

High

274912

LRP5
Low-density lipoprotein receptor-related protein 5

1

19

High-throughput

0.489

High

287603

LRP6
Low-density lipoprotein receptor-related protein 6

1

19

High-throughput

0.489

High

1212609

HECD3
E3 ubiquitin-protein ligase HECTD3

1

12

High-throughput

0.489

High

1311388

ANKH1
Ankyrin repeat and KH domain-containing protein 1

1

3

High-throughput

0.489

High

1326618

KLH36
Kelch-like protein 36

1

3

High-throughput

0.489

High

1411497

RIC8B
Chaperone Ric-8B

1

1

High-throughput

0.489

High

1411509

IPP
Actin-binding protein IPP

1

4

High-throughput

0.489

High

123174

DX39A
ATP-dependent RNA helicase DDX39A

1

4

Small-scale

0.479

High

162677

ANM5
Protein arginine N-methyltransferase 5

1

5

Small-scale

0.479

High

177708

SMAD7
Mothers against decapentaplegic homolog 7

1

7

Small-scale

0.479

High

188354

HDAC3
Histone deacetylase 3

1

13

Small-scale

0.479

High

243718

SMCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

1

7

Small-scale

0.479

High

254216

CTND1
Catenin delta-1

1

3

Small-scale

0.479

High

273226

CAND2
Cullin-associated NEDD8-dissociated protein 2

1

4

Small-scale

0.479

High

276514

PDCD6
Programmed cell death protein 6

1

1

Small-scale

0.479

High

277801

H2AY
Core histone macro-H2A.1

1

5

Small-scale

0.479

High

336477

SVIL
Supervillin

1

7

Small-scale

0.479

High

347898

BAG3
BAG family molecular chaperone regulator 3

1

2

High-throughput

0.479

High

348691

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

2

Small-scale

0.479

High

461875

HS90A
Heat shock protein HSP 90-alpha

1

2

Small-scale

0.479

High

485373

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

4

Small-scale

0.479

High

502108

H2AZ
Histone H2A.Z

1

6

Small-scale

0.479

High

559479

XRCC5
X-ray repair cross-complementing protein 5

1

1

Small-scale

0.479

High

608725

DDX5
Probable ATP-dependent RNA helicase DDX5

1

2

Small-scale

0.479

High

648220

NDKB
Nucleoside diphosphate kinase B

1

1

Small-scale

0.479

High

729111

HNRH3
Heterogeneous nuclear ribonucleoprotein H3

1

3

Small-scale

0.479

High

754967

H2B1B
Histone H2B type 1-B

1

4

Small-scale

0.479

High

764422

CTNA1
Catenin alpha-1

1

1

Small-scale

0.479

High

764999

CTNB1
Catenin beta-1

1

9

Small-scale

0.479

High

827474

MLH1
DNA mismatch repair protein Mlh1

1

1

Small-scale

0.479

High

838168

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

2

Small-scale

0.479

High

851804

NKX21
Homeobox protein Nkx-2.1

1

5

High-throughput

0.479

High

909675

ROA3
Heterogeneous nuclear ribonucleoprotein A3

1

3

Small-scale

0.479

High

980228

H4
Histone H4

1

4

Small-scale

0.479

High

987181

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

4

Small-scale

0.479

High

1014600

SMAD3
Mothers against decapentaplegic homolog 3

1

7

Small-scale

0.479

High

1023280

RBM3
RNA-binding protein 3

1

1

Small-scale

0.479

High

1065395

SSRP1
FACT complex subunit SSRP1

1

8

Small-scale

0.479

High

1093303

FLII
Protein flightless-1 homolog

1

7

Small-scale

0.479

High

1106687

SMAD4
Mothers against decapentaplegic homolog 4

1

7

Small-scale

0.479

High

1111854

TRA2A
Transformer-2 protein homolog alpha

1

2

Small-scale

0.479

High

1134356

IMB1
Importin subunit beta-1

1

11

Small-scale

0.479

High

1153892

SMAD2
Mothers against decapentaplegic homolog 2

1

7

Small-scale

0.479

High

1239472

H3C
Histone H3.3C

1

10

Small-scale

0.479

High

1259634

H2AV
Histone H2A.V

1

6

Small-scale

0.479

High

1369363

DDX17
Probable ATP-dependent RNA helicase DDX17

1

2

Small-scale

0.479

High

1402510

NEB2
Neurabin-2

1

5

Small-scale

0.479

High

1410357

MEP50
Methylosome protein WDR77

1

1

Small-scale

0.479

High

1411498

BCLF1
Bcl-2-associated transcription factor 1

1

2

Small-scale

0.479

High

1411506

RUVB1
RuvB-like 1

1

1

Small-scale

0.479

High

1411508

TR150
Thyroid hormone receptor-associated protein 3

1

3

Small-scale

0.479

High

207637

DHX15
ATP-dependent RNA helicase DHX15

1

0

Small-scale

0.458

High

290978

PPM1B
Protein phosphatase 1B

1

0

Small-scale

0.458

High

756322

MCM7
DNA replication licensing factor MCM7

1

0

Small-scale

0.458

High

862965

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

0

Small-scale

0.458

High

925968

TCP4
Activated RNA polymerase II transcriptional coactivator p15

1

0

Small-scale

0.458

High

1028704

U2AF1
Splicing factor U2AF 35 kDa subunit

1

0

Small-scale

0.458

High

1139672

SYK
Lysine--tRNA ligase

1

0

Small-scale

0.458

High

1146615

TMED2
Transmembrane emp24 domain-containing protein 2

1

0

Small-scale

0.458

High

1154289

UB2V2
Ubiquitin-conjugating enzyme E2 variant 2

1

0

Small-scale

0.458

High

1157606

TAF12
Transcription initiation factor TFIID subunit 12

1

0

Small-scale

0.458

High

1275882

PCLI1
PTB-containing, cubilin and LRP1-interacting protein

1

0

Small-scale

0.458

High

1411505

RALY
RNA-binding protein Raly

1

0

Small-scale

0.458

High

1411507

PDIP2
Polymerase delta-interacting protein 2

1

0

Small-scale

0.458

High

167642

GIPC1
PDZ domain-containing protein GIPC1

1

1

Small-scale

0.437

High

171314

MYPT1
Protein phosphatase 1 regulatory subunit 12A

1

20

Small-scale

0.437

High

175988

N4BP3
NEDD4-binding protein 3

1

9

Small-scale

0.437

High

612293

ARF4
ADP-ribosylation factor 4

1

3

Small-scale

0.437

High

801497

HSPA9
Stress-70 protein, mitochondrial

1

4

Small-scale

0.437

High

955529

CDC42
Cell division control protein 42 homolog

1

2

Small-scale

0.437

High

958813

ARF3
ADP-ribosylation factor 3

1

3

Small-scale

0.437

High

975206

ARF6
ADP-ribosylation factor 6

1

3

Small-scale

0.437

High

1014955

ARF1
ADP-ribosylation factor 1

1

3

Small-scale

0.437

High

1058924

ZO1
Tight junction protein 1

1

1

Small-scale

0.437

High

1150945

TRIPB
Thyroid receptor-interacting protein 11

1

1

Small-scale

0.437

High

1164533

MIC60
MICOS complex subunit MIC60

1

1

Small-scale

0.437

High

1204218

PDZ11
PDZ domain-containing protein 11

1

2

Small-scale

0.437

High

1256901

TM1L2
TOM1-like protein 2

1

4

Small-scale

0.437

High

1293288

LSR
Lipolysis-stimulated lipoprotein receptor

1

1

Small-scale

0.437

High

1385421

EFHD2
EF-hand domain-containing protein D2

1

1

Small-scale

0.437

High

1399493

IPO9
Importin-9

1

20

Small-scale

0.437

High

1410812

AIF1L
Allograft inflammatory factor 1-like

1

2

Small-scale

0.437

High

1411495

UN45A
Protein unc-45 homolog A

1

10

Small-scale

0.437

High

1411496

ARL8B
ADP-ribosylation factor-like protein 8B

1

3

Small-scale

0.437

High

1411510

NS1BP
Influenza virus NS1A-binding protein

1

5

Small-scale

0.437

High

1130660

GSE1
Genetic suppressor element 1

1

0

High-throughput

0.279

Low

208728

SI1L1
Signal-induced proliferation-associated 1-like protein 1

1

0

Small-scale

0.249

Low

964728

DCAF7
DDB1- and CUL4-associated factor 7

1

0

Small-scale

0.249

Low

989869

GNAI1
Guanine nucleotide-binding protein G(i) subunit alpha-1

1

0

Small-scale

0.249

Low

994952

SC11A
Signal peptidase complex catalytic subunit SEC11A

1

0

Small-scale

0.249

Low

1010705

DCD
Dermcidin

1

0

Small-scale

0.249

Low

1027157

REEP5
Receptor expression-enhancing protein 5

1

0

Small-scale

0.249

Low

1233453

LTOR1
Ragulator complex protein LAMTOR1

1

0

Small-scale

0.249

Low

1309153

MISP
Mitotic interactor and substrate of PLK1

1

0

Small-scale

0.249

Low

1323446

NUP93
Nuclear pore complex protein Nup93

1

0

Small-scale

0.249

Low

1328190

JAGN1
Protein jagunal homolog 1

1

0

Small-scale

0.249

Low

1390257

NRBF2
Nuclear receptor-binding factor 2

1

0

Small-scale

0.249

Low

1394701

ESIP1
Epithelial-stromal interaction protein 1

1

0

Small-scale

0.249

Low

1411499

TMOD3
Tropomodulin-3

1

0

Small-scale

0.249

Low

1411502

LIMA1
LIM domain and actin-binding protein 1

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025