Protein: FA53C
Protein FAM53C

Gene: FA53C, FAM53C
Organism: Homo sapiens
Interactions: 72
UniProt ID: Q9NYF3

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0006606 - protein import into nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1116061

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

9

2

High-throughput

0.755

High

966943

1433G
14-3-3 protein gamma

6

14

High-throughput

0.744

High

990796

1433Z
14-3-3 protein zeta/delta

5

14

High-throughput

0.723

High

1452557

DYR1B
Dual specificity tyrosine-phosphorylation-regulated kinase 1B

5

2

High-throughput

0.722

High

691481

1433T
14-3-3 protein theta

5

14

High-throughput

0.714

High

730293

1433B
14-3-3 protein beta/alpha

5

14

High-throughput

0.714

High

972062

1433E
14-3-3 protein epsilon

4

2

High-throughput

0.695

High

920312

PLK1
Serine/threonine-protein kinase PLK1

5

0

High-throughput

0.691

High

1049837

1433F
14-3-3 protein eta

5

14

High-throughput

0.652

High

250350

VINEX
Vinexin

2

0

High-throughput

0.580

High

730920

1433S
14-3-3 protein sigma

1

14

High-throughput

0.573

High

1232613

Q6FHY5
MEOX2 protein

1

3

High-throughput

0.515

High

1435371

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.513

High

894210

MEOX2
Homeobox protein MOX-2

1

3

High-throughput

0.481

High

173465

XPO1
Exportin-1

1

3

High-throughput

0.479

High

637964

NF1
Neurofibromin

1

1

High-throughput

0.479

High

1410260

F110A
Protein FAM110A

1

1

High-throughput

0.479

High

1452548

XPO7
Exportin-7

1

3

High-throughput

0.479

High

1452556

CBY1
Protein chibby homolog 1

1

1

High-throughput

0.479

High

1452559

V9HW98
14-3-3 protein epsilon

1

2

High-throughput

0.470

High

269622

SRGP2
SLIT-ROBO Rho GTPase-activating protein 2

1

0

High-throughput

0.458

High

719270

MPIP2
M-phase inducer phosphatase 2

1

0

High-throughput

0.458

High

941071

HDAC4
Histone deacetylase 4

1

0

High-throughput

0.458

High

1025598

CDK16
Cyclin-dependent kinase 16

1

0

High-throughput

0.458

High

1114470

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1134068

ZN638
Zinc finger protein 638

1

0

High-throughput

0.458

High

1400870

RAB3I
Rab-3A-interacting protein

1

0

High-throughput

0.458

High

1402220

TESK2
Dual specificity testis-specific protein kinase 2

1

0

High-throughput

0.458

High

1409792

SIN1
Target of rapamycin complex 2 subunit MAPKAP1

1

0

High-throughput

0.458

High

1452545

SH3B4
SH3 domain-binding protein 4

1

0

High-throughput

0.458

High

1452551

ZBT21
Zinc finger and BTB domain-containing protein 21

1

0

High-throughput

0.458

High

1452552

PPM1H
Protein phosphatase 1H

1

0

High-throughput

0.458

High

1452553

TRI33
E3 ubiquitin-protein ligase TRIM33

1

0

High-throughput

0.458

High

1258595

CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2

1

1

High-throughput

0.445

High

1433316

WNK1
Serine/threonine-protein kinase WNK1

1

0

High-throughput

0.438

High

230578

KIF1C
Kinesin-like protein KIF1C

1

1

High-throughput

0.437

High

936465

AFAD
Afadin

1

1

High-throughput

0.437

High

1216097

SPD2A
SH3 and PX domain-containing protein 2A

1

1

High-throughput

0.437

High

1219627

DEN4C
DENN domain-containing protein 4C

1

1

High-throughput

0.437

High

1257046

SYDE1
Rho GTPase-activating protein SYDE1

1

1

High-throughput

0.437

High

1349478

F110B
Protein FAM110B

1

1

High-throughput

0.437

High

1352614

DEN1A
DENN domain-containing protein 1A

1

1

High-throughput

0.437

High

1447270

KI13B
Kinesin-like protein KIF13B

1

1

High-throughput

0.437

High

1452549

NGAP
Ras GTPase-activating protein nGAP

1

1

High-throughput

0.437

High

1452555

GAB2
GRB2-associated-binding protein 2

1

2

High-throughput

0.437

High

964756

DCAF7
DDB1- and CUL4-associated factor 7

4

0

High-throughput

0.363

High

222218

NCK2
Cytoplasmic protein NCK2

3

0

High-throughput

0.352

High

881745

FNTB
Protein farnesyltransferase subunit beta

3

0

High-throughput

0.347

High

1094994

TRAF3
TNF receptor-associated factor 3

2

0

High-throughput

0.298

High

176884

DCLK1
Serine/threonine-protein kinase DCLK1

1

0

High-throughput

0.249

Low

208742

SI1L1
Signal-induced proliferation-associated 1-like protein 1

1

0

High-throughput

0.249

Low

245279

MAST3
Microtubule-associated serine/threonine-protein kinase 3

1

0

High-throughput

0.249

Low

252180

IF4E2
Eukaryotic translation initiation factor 4E type 2

1

0

High-throughput

0.249

Low

281438

GGYF1
GRB10-interacting GYF protein 1

1

0

High-throughput

0.249

Low

339111

NADK
NAD kinase

1

0

High-throughput

0.249

Low

1092502

TIAM1
Rho guanine nucleotide exchange factor TIAM1

1

0

High-throughput

0.249

Low

1129987

MELK
Maternal embryonic leucine zipper kinase

1

0

High-throughput

0.249

Low

1187140

TBC25
TBC1 domain family member 25

1

0

High-throughput

0.249

Low

1216030

M3K21
Mitogen-activated protein kinase kinase kinase 21

1

0

High-throughput

0.249

Low

1229904

AN34A
Ankyrin repeat domain-containing protein 34A

1

0

High-throughput

0.249

Low

1234985

PKHA7
Pleckstrin homology domain-containing family A member 7

1

0

High-throughput

0.249

Low

1286550

PHLB2
Pleckstrin homology-like domain family B member 2

1

0

High-throughput

0.249

Low

1309255

KSR1
Kinase suppressor of Ras 1

1

0

High-throughput

0.249

Low

1357431

DEP1B
DEP domain-containing protein 1B

1

0

High-throughput

0.249

Low

1360405

SRS12
Serine/arginine-rich splicing factor 12

1

0

High-throughput

0.249

Low

1401122

MAGI1
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1

1

0

High-throughput

0.249

Low

1412884

RTKN
Rhotekin

1

0

High-throughput

0.249

Low

1452546

LRFN1
Leucine-rich repeat and fibronectin type III domain-containing protein 1

1

0

High-throughput

0.249

Low

1452547

LIMA1
LIM domain and actin-binding protein 1

1

0

High-throughput

0.249

Low

1452550

UBP21
Ubiquitin carboxyl-terminal hydrolase 21

1

0

High-throughput

0.249

Low

1452554

AGAP1
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1

1

0

High-throughput

0.249

Low

1452558

KCTD3
BTB/POZ domain-containing protein KCTD3

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025