Protein: NSF1C
NSFL1 cofactor p47 (UBX domain-containing protein 2C) (p97 cofactor p47)

Gene: NSF1C, NSFL1C
Organism: Homo sapiens
Interactions: 141
UniProt ID: Q9UNZ2

Gene Ontology (top 5):
GO:0000045 - autophagosome assembly
GO:0000132 - establishment of mitotic spindle orientation
GO:0005634 - nucleus
GO:0005694 - chromosome
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

935295

TERA
Transitional endoplasmic reticulum ATPase

36

11

Small-scale

0.995

High

508839

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

8

5

Small-scale

0.967

High

1419769

ASPC1
Tether containing UBX domain for GLUT4

3

7

High-throughput

0.861

High

999316

UBX2A
UBX domain-containing protein 2A

2

5

High-throughput

0.789

High

320799

UBXN7
UBX domain-containing protein 7

2

7

Small-scale

0.754

High

1462359

FAF1
FAS-associated factor 1

2

10

High-throughput

0.754

High

1420261

UBXN6
UBX domain-containing protein 6

2

7

High-throughput

0.737

High

1154964

NEDD8
Ubiquitin-like protein NEDD8

1

1

Small-scale

0.724

High

1135613

UBX2B
UBX domain-containing protein 2B

1

3

High-throughput

0.691

High

1394996

VCIP1
Deubiquitinating protein VCPIP1

4

2

Small-scale

0.686

High

1347671

NPL4
Nuclear protein localization protein 4 homolog

3

2

Small-scale

0.640

High

1385376

FGGY
FGGY carbohydrate kinase domain-containing protein

3

0

High-throughput

0.638

High

425679

ISG15
Ubiquitin-like protein ISG15

1

6

Small-scale

0.618

High

1046441

UBXN1
UBX domain-containing protein 1

1

5

Small-scale

0.618

High

1397088

UBX10
UBX domain-containing protein 10

1

1

High-throughput

0.618

High

1459886

UBQL2
Ubiquilin-2

1

1

High-throughput

0.618

High

1462426

NSF1C
NSFL1 cofactor p47

1

3

High-throughput

0.618

High

1096278

TADBP
TAR DNA-binding protein 43

2

0

High-throughput

0.601

High

1462433

NEMO
NF-kappa-B essential modulator

2

3

Small-scale

0.584

High

1452412

SNTG2
Gamma-2-syntrophin

1

2

Small-scale

0.561

High

575218

IDE
Insulin-degrading enzyme

2

0

Small-scale

0.559

High

831653

CCNF
Cyclin-F

2

0

High-throughput

0.559

High

1370000

UFD1
Ubiquitin recognition factor in ER-associated degradation protein 1

2

0

High-throughput

0.559

High

1381439

VCF1
Protein VCF1

2

1

High-throughput

0.558

High

1419609

NUF2
Kinetochore protein Nuf2

1

1

High-throughput

0.536

High

770331

RL22
Large ribosomal subunit protein eL22

1

0

High-throughput

0.518

High

1051132

LIPS
Hormone-sensitive lipase

1

0

High-throughput

0.518

High

423462

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.513

High

530587

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.513

High

954763

SEM1
26S proteasome complex subunit SEM1

1

0

Small-scale

0.513

High

1060142

BAX
Apoptosis regulator BAX

1

0

High-throughput

0.513

High

1234631

P4R3A
Serine/threonine-protein phosphatase 4 regulatory subunit 3A

1

0

High-throughput

0.513

High

1462430

FBX7
F-box only protein 7

1

0

High-throughput

0.513

High

891887

GSK3B
Glycogen synthase kinase-3 beta

1

4

High-throughput

0.508

High

1436038

PHAX
Phosphorylated adapter RNA export protein

1

1

High-throughput

0.508

High

443559

CDK1
Cyclin-dependent kinase 1

1

1

Small-scale

0.501

High

605850

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

2

Small-scale

0.501

High

1097924

STX5
Syntaxin-5

1

1

Small-scale

0.501

High

1394417

NGLY1
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase

1

1

Small-scale

0.501

High

1395898

TOPK
Lymphokine-activated killer T-cell-originated protein kinase

1

0

Small-scale

0.480

High

126874

RHOD
Rho-related GTP-binding protein RhoD

1

4

High-throughput

0.479

High

261924

PP1RB
E3 ubiquitin-protein ligase PPP1R11

1

2

High-throughput

0.479

High

376099

RASK
GTPase KRas

1

1

High-throughput

0.479

High

405358

OAT
Ornithine aminotransferase, mitochondrial

1

1

Small-scale

0.479

High

556425

CADH1
Cadherin-1

1

1

High-throughput

0.479

High

590037

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

773084

MYH9
Myosin-9

1

2

Small-scale

0.479

High

786934

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

8

High-throughput

0.479

High

880744

LMAN1
Protein ERGIC-53

1

1

High-throughput

0.479

High

887742

PSB2
Proteasome subunit beta type-2

1

1

Small-scale

0.479

High

910253

RND2
Rho-related GTP-binding protein RhoN

1

5

High-throughput

0.479

High

955757

CDC42
Cell division control protein 42 homolog

1

2

High-throughput

0.479

High

962638

RHOA
Transforming protein RhoA

1

3

High-throughput

0.479

High

1013475

LACTB
Serine beta-lactamase-like protein LACTB, mitochondrial

1

2

High-throughput

0.479

High

1015906

RHOG
Rho-related GTP-binding protein RhoG

1

2

High-throughput

0.479

High

1063699

GOGA2
Golgin subfamily A member 2

1

3

High-throughput

0.479

High

1096862

RFA4
Replication protein A 30 kDa subunit

1

1

High-throughput

0.479

High

1112798

CUL1
Cullin-1

1

3

High-throughput

0.479

High

1113027

CUL2
Cullin-2

1

3

High-throughput

0.479

High

1114663

CUL3
Cullin-3

1

3

High-throughput

0.479

High

1148886

PP1R7
Protein phosphatase 1 regulatory subunit 7

1

3

High-throughput

0.479

High

1151931

RHOH
Rho-related GTP-binding protein RhoH

1

3

High-throughput

0.479

High

1155906

EZH2
Histone-lysine N-methyltransferase EZH2

1

1

High-throughput

0.479

High

1256105

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

1280604

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

1

High-throughput

0.479

High

1311131

UBR1
E3 ubiquitin-protein ligase UBR1

1

1

High-throughput

0.479

High

1366913

RND1
Rho-related GTP-binding protein Rho6

1

6

High-throughput

0.479

High

1438245

RHOF
Rho-related GTP-binding protein RhoF

1

4

High-throughput

0.479

High

1459319

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

1461303

MYH13
Myosin-13

1

2

High-throughput

0.479

High

1461977

MYO6
Unconventional myosin-VI

1

3

High-throughput

0.479

High

1462427

PLAP
Phospholipase A-2-activating protein

1

3

Small-scale

0.479

High

1462428

FBW1A
F-box/WD repeat-containing protein 1A

1

2

High-throughput

0.479

High

450353

ACBP
Acyl-CoA-binding protein

1

1

High-throughput

0.464

High

122878

KIF2A
Kinesin-like protein KIF2A

1

0

High-throughput

0.458

High

128341

PSD12
26S proteasome non-ATPase regulatory subunit 12

1

0

Small-scale

0.458

High

129558

MEN1
Menin

1

0

High-throughput

0.458

High

224053

GET3
ATPase GET3

1

0

Small-scale

0.458

High

247030

KDM1A
Lysine-specific histone demethylase 1A

1

0

High-throughput

0.458

High

326633

MFN2
Mitofusin-2

1

0

High-throughput

0.458

High

346503

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

373502

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

437039

K1C18
Keratin, type I cytoskeletal 18

1

0

High-throughput

0.458

High

558499

XRCC6
X-ray repair cross-complementing protein 6

1

0

High-throughput

0.458

High

599233

IL7RA
Interleukin-7 receptor subunit alpha

1

0

High-throughput

0.458

High

604763

UBF1
Nucleolar transcription factor 1

1

0

High-throughput

0.458

High

637978

NF1
Neurofibromin

1

0

Small-scale

0.458

High

696868

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

762373

GPC1
Glypican-1 [Cleaved into: Secreted glypican-1]

1

0

High-throughput

0.458

High

765123

CTNB1
Catenin beta-1

1

0

High-throughput

0.458

High

904200

BAP31
B-cell receptor-associated protein 31

1

0

High-throughput

0.458

High

941093

HDAC4
Histone deacetylase 4

1

0

High-throughput

0.458

High

975524

PRS10
26S proteasome regulatory subunit 10B

1

0

Small-scale

0.458

High

989168

AP2B1
AP-2 complex subunit beta

1

0

High-throughput

0.458

High

991962

DYLT1
Dynein light chain Tctex-type 1

1

0

High-throughput

0.458

High

1005250

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.458

High

1087342

STX4
Syntaxin-4

1

0

High-throughput

0.458

High

1098168

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

0

High-throughput

0.458

High

1117528

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

0

Small-scale

0.458

High

1121373

TRI14
Tripartite motif-containing protein 14

1

0

High-throughput

0.458

High

1161442

HIF1A
Hypoxia-inducible factor 1-alpha

1

0

High-throughput

0.458

High

1219004

TET5C
Terminal nucleotidyltransferase 5C

1

0

High-throughput

0.458

High

1257844

ACD11
Acyl-CoA dehydrogenase family member 11

1

0

High-throughput

0.458

High

1258325

MOB2
MOB kinase activator 2

1

0

High-throughput

0.458

High

1276972

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1278941

BRAP
BRCA1-associated protein

1

0

High-throughput

0.458

High

1293698

DYR2
Dihydrofolate reductase 2, mitochondrial

1

0

High-throughput

0.458

High

1364695

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

1396865

SNX27
Sorting nexin-27

1

0

High-throughput

0.458

High

1417101

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

0

Small-scale

0.458

High

1429397

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

Small-scale

0.458

High

1446551

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.458

High

1447017

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

0

Small-scale

0.458

High

1448043

PXMP2
Peroxisomal membrane protein 2

1

0

High-throughput

0.458

High

1462429

FND3A
Fibronectin type-III domain-containing protein 3A

1

0

High-throughput

0.458

High

1462432

MTCH2
Mitochondrial carrier homolog 2

1

0

High-throughput

0.458

High

613485

VINC
Vinculin

1

3

High-throughput

0.445

High

1449923

DDX28
Probable ATP-dependent RNA helicase DDX28

1

1

High-throughput

0.445

High

788820

SRP14
Signal recognition particle 14 kDa protein

1

0

High-throughput

0.438

High

813499

AN32A
Acidic leucine-rich nuclear phosphoprotein 32 family member A

1

0

High-throughput

0.438

High

1371216

GLMN
Glomulin

1

0

High-throughput

0.438

High

318915

RHBT1
Rho-related BTB domain-containing protein 1

1

4

High-throughput

0.437

High

1419434

RHBT2
Rho-related BTB domain-containing protein 2

1

4

High-throughput

0.437

High

1450975

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

1

High-throughput

0.437

High

404958

PRIO
Major prion protein

1

0

High-throughput

0.426

High

1236083

LIN54
Protein lin-54 homolog

1

0

Small-scale

0.426

High

1315732

DND1
Dead end protein homolog 1

1

0

High-throughput

0.426

High

887336

CEBPA
CCAAT/enhancer-binding protein alpha

1

0

High-throughput

0.391

High

1142703

PDK1
[Pyruvate dehydrogenase

1

0

High-throughput

0.279

Low

106856

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

136998

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

0

High-throughput

0.249

Low

341173

DIRA3
GTP-binding protein Di-Ras3

1

0

High-throughput

0.249

Low

426151

PPB1
Alkaline phosphatase, placental type

1

0

High-throughput

0.249

Low

643139

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

0

High-throughput

0.249

Low

769518

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

879617

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.249

Low

1323045

CXD3
Gap junction delta-3 protein

1

0

High-throughput

0.249

Low

1327003

DJC22
DnaJ homolog subfamily C member 22

1

0

High-throughput

0.249

Low

1462142

PCDB8
Protocadherin beta-8

1

0

High-throughput

0.249

Low

1462431

FA32A
Protein FAM32A

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025