Protein: BIK
Bcl-2-interacting killer (Apoptosis inducer NBK) (BIP1) (BP4)

Gene: BIK
Organism: Homo sapiens
Interactions: 135
UniProt ID: Q13323

Gene Ontology (top 5):
GO:0006915 - apoptotic process
GO:0008584 - male gonad development
GO:0008637 - apoptotic mitochondrial changes
GO:0012505 - endomembrane system
GO:0031334 - positive regulation of protein-containing complex assembly

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

992072

B2CL1
Bcl-2-like protein 1

12

6

Small-scale

0.760

High

1031769

B2CL2
Bcl-2-like protein 2

8

6

Small-scale

0.754

High

489410

BCL2
Apoptosis regulator Bcl-2

11

6

Small-scale

0.754

High

1031773

FATE1
Fetal and adult testis-expressed transcript protein

5

0

High-throughput

0.689

High

1031797

B2L10
Bcl-2-like protein 10

4

0

Small-scale

0.655

High

1031735

B2LA1
Bcl-2-related protein A1

5

4

Small-scale

0.653

High

992160

MCL1
Induced myeloid leukemia cell differentiation protein Mcl-1

3

5

Small-scale

0.639

High

1031798

TM14B
Transmembrane protein 14B

2

1

High-throughput

0.606

High

1031803

TM14C
Transmembrane protein 14C

2

1

High-throughput

0.606

High

1031809

STX8
Syntaxin-8

2

1

High-throughput

0.606

High

123583

PGRC1
Membrane-associated progesterone receptor component 1

2

0

High-throughput

0.580

High

644391

PPLA
Cardiac phospholamban

2

0

High-throughput

0.580

High

1022012

BNIP3
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3

2

0

High-throughput

0.580

High

1031753

TM199
Transmembrane protein 199

2

0

High-throughput

0.580

High

1031799

AIG1
Androgen-induced gene 1 protein

2

0

High-throughput

0.580

High

1031814

UBIA1
UbiA prenyltransferase domain-containing protein 1

2

0

High-throughput

0.580

High

216720

CREB3
Cyclic AMP-responsive element-binding protein 3

2

0

High-throughput

0.565

High

306793

VAMP5
Vesicle-associated membrane protein 5

2

2

High-throughput

0.553

High

313590

CNIH1
Protein cornichon homolog 1

2

1

High-throughput

0.553

High

828106

CY561
Transmembrane ascorbate-dependent reductase CYB561

2

1

High-throughput

0.553

High

982730

PLP2
Proteolipid protein 2

2

2

High-throughput

0.553

High

1031733

VAMP3
Vesicle-associated membrane protein 3

2

2

High-throughput

0.553

High

1031756

SERP2
Stress-associated endoplasmic reticulum protein 2

2

1

High-throughput

0.553

High

1031759

CNIH3
Protein cornichon homolog 3

2

1

High-throughput

0.553

High

1031779

CKLF7
CKLF-like MARVEL transmembrane domain-containing protein 7

2

2

High-throughput

0.553

High

1031795

REEP4
Receptor expression-enhancing protein 4

2

1

High-throughput

0.553

High

1031816

SERP1
Stress-associated endoplasmic reticulum protein 1

2

1

High-throughput

0.553

High

802835

CRKL
Crk-like protein

1

0

High-throughput

0.518

High

1031751

TARG1
Trafficking regulator of GLUT4 1

1

1

High-throughput

0.481

High

61026

A5PKU2
TUSC5 protein

1

1

High-throughput

0.470

High

1031775

Q96AL5
PBX3 protein

1

1

High-throughput

0.470

High

964825

PMP22
Peripheral myelin protein 22

1

0

High-throughput

0.460

High

1031731

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

0

High-throughput

0.460

High

206744

B2L11
Bcl-2-like protein 11

1

0

Small-scale

0.458

High

874892

TERA
Transitional endoplasmic reticulum ATPase

1

0

Small-scale

0.458

High

934136

CSK21
Casein kinase II subunit alpha

1

0

Small-scale

0.458

High

3078

A0A0S2Z3D2
Bcl-2-like protein 1

1

3

High-throughput

0.457

High

1031743

Q5T7Y6
Protein S100

1

1

High-throughput

0.451

High

151570

GOSR2
Golgi SNAP receptor complex member 2

1

1

High-throughput

0.439

High

169452

BET1
BET1 homolog

1

1

High-throughput

0.439

High

261659

VAMP4
Vesicle-associated membrane protein 4

1

2

High-throughput

0.439

High

276314

UPK1B
Uroplakin-1b

1

1

High-throughput

0.439

High

310623

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

1

High-throughput

0.439

High

615215

S10A1
Protein S100-A1

1

1

High-throughput

0.439

High

773163

PBX3
Pre-B-cell leukemia transcription factor 3

1

1

High-throughput

0.439

High

1031738

ORML2
ORM1-like protein 2

1

1

High-throughput

0.439

High

1031783

REEP6
Receptor expression-enhancing protein 6

1

1

High-throughput

0.439

High

1031801

VAPA
Vesicle-associated membrane protein-associated protein A

1

1

High-throughput

0.439

High

1031802

ORML1
ORM1-like protein 1

1

1

High-throughput

0.439

High

1031804

VTI1B
Vesicle transport through interaction with t-SNAREs homolog 1B

1

1

High-throughput

0.439

High

1031811

PLLP
Plasmolipin

1

2

High-throughput

0.439

High

70804

SMIM1
Small integral membrane protein 1

2

0

High-throughput

0.316

High

183371

KCNN4
Intermediate conductance calcium-activated potassium channel protein 4

2

0

High-throughput

0.316

High

196769

CYB5B
Cytochrome b5 type B

2

0

High-throughput

0.316

High

215815

G6PT1
Glucose-6-phosphate exchanger SLC37A4

2

0

High-throughput

0.316

High

305440

ZFPL1
Zinc finger protein-like 1

2

0

High-throughput

0.316

High

313004

BMP10
Bone morphogenetic protein 10

2

0

High-throughput

0.316

High

396348

APOD
Apolipoprotein D

2

0

High-throughput

0.316

High

519334

FCGR1
High affinity immunoglobulin gamma Fc receptor I

2

0

High-throughput

0.316

High

565354

TMM11
Transmembrane protein 11, mitochondrial

2

0

High-throughput

0.316

High

583877

CD53
Leukocyte surface antigen CD53

2

0

High-throughput

0.316

High

601787

CD72
B-cell differentiation antigen CD72

2

0

High-throughput

0.316

High

888249

MYPR
Myelin proteolipid protein

2

0

High-throughput

0.316

High

1031732

GRM2
Metabotropic glutamate receptor 2

2

0

High-throughput

0.316

High

1031734

ADIPO
Adiponectin

2

0

High-throughput

0.316

High

1031736

EX3L2
Exocyst complex component 3-like protein 2

2

0

High-throughput

0.316

High

1031737

CTXN3
Cortexin-3

2

0

High-throughput

0.316

High

1031739

SGMR2
Sigma intracellular receptor 2

2

0

High-throughput

0.316

High

1031740

TTMP
TPA-induced transmembrane protein

2

0

High-throughput

0.316

High

1031741

M4A13
Membrane-spanning 4-domains subfamily A member 13

2

0

High-throughput

0.316

High

1031742

F209A
Protein FAM209A

2

0

High-throughput

0.316

High

1031744

TSPO2
Translocator protein 2

2

0

High-throughput

0.316

High

1031745

PLPP4
Phospholipid phosphatase 4

2

0

High-throughput

0.316

High

1031746

BRID5
BRICHOS domain-containing protein 5

2

0

High-throughput

0.316

High

1031747

TM107
Transmembrane protein 107

2

0

High-throughput

0.316

High

1031748

S35E3
Solute carrier family 35 member E3

2

0

High-throughput

0.316

High

1031749

ANR46
Ankyrin repeat domain-containing protein 46

2

0

High-throughput

0.316

High

1031752

NRM
Nurim

2

0

High-throughput

0.316

High

1031754

TM86B
Lysoplasmalogenase TMEM86B

2

0

High-throughput

0.316

High

1031755

CLD19
Claudin-19

2

0

High-throughput

0.316

High

1031757

NRAC
Nutritionally-regulated adipose and cardiac enriched protein homolog

2

0

High-throughput

0.316

High

1031758

T229B
Transmembrane protein 229B

2

0

High-throughput

0.316

High

1031760

TM254
Transmembrane protein 254

2

0

High-throughput

0.316

High

1031761

GPX8
Probable glutathione peroxidase 8

2

0

High-throughput

0.316

High

1031762

BT2A2
Butyrophilin subfamily 2 member A2

2

0

High-throughput

0.316

High

1031763

CD003
Uncharacterized protein C4orf3

2

0

High-throughput

0.316

High

1031767

S39A7
Zinc transporter SLC39A7

2

0

High-throughput

0.316

High

1031768

FAM3C
Protein FAM3C

2

0

High-throughput

0.316

High

1031772

SCAM4
Secretory carrier-associated membrane protein 4

2

0

High-throughput

0.316

High

1031774

LFG3
Protein lifeguard 3

2

0

High-throughput

0.316

High

1031777

F241B
Protein FAM241B

2

0

High-throughput

0.316

High

1031778

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

2

0

High-throughput

0.316

High

1031781

RUSF1
RUS family member 1

2

0

High-throughput

0.316

High

1031782

TMM80
Transmembrane protein 80

2

0

High-throughput

0.316

High

1031784

SC22A
Vesicle-trafficking protein SEC22a

2

0

High-throughput

0.316

High

1031787

TM243
Transmembrane protein 243

2

0

High-throughput

0.316

High

1031788

ALG8
Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase

2

0

High-throughput

0.316

High

1031791

ELOV4
Very long chain fatty acid elongase 4

2

0

High-throughput

0.316

High

1031792

TM222
Transmembrane protein 222

2

0

High-throughput

0.316

High

1031794

TMM60
Transmembrane protein 60

2

0

High-throughput

0.316

High

1031800

MARH5
E3 ubiquitin-protein ligase MARCHF5

2

0

High-throughput

0.316

High

1031805

NAT8
N-acetyltransferase 8

2

0

High-throughput

0.316

High

1031806

PGAP2
Post-GPI attachment to proteins factor 2

2

0

High-throughput

0.316

High

1031807

AGRE2
Adhesion G protein-coupled receptor E2

2

0

High-throughput

0.316

High

1031810

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

2

0

High-throughput

0.316

High

1031812

INSI2
Insulin-induced gene 2 protein

2

0

High-throughput

0.316

High

1031815

SELK
Selenoprotein K

2

0

High-throughput

0.316

High

1031765

ASB11
Ankyrin repeat and SOCS box protein 11

1

0

Small-scale

0.301

High

622788

COT2
COUP transcription factor 2

1

0

High-throughput

0.282

High

1031770

TANK
TRAF family member-associated NF-kappa-B activator

1

0

High-throughput

0.282

High

146970

C2C2L
Phospholipid transfer protein C2CD2L

1

0

High-throughput

0.268

Low

483850

DWORF
Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator DWORF

1

0

High-throughput

0.268

Low

987317

CCG1
Voltage-dependent calcium channel gamma-1 subunit

1

0

High-throughput

0.268

Low

1031750

ZNT8
Proton-coupled zinc antiporter SLC30A8

1

0

High-throughput

0.268

Low

1031764

GIMA1
GTPase IMAP family member 1

1

0

High-throughput

0.268

Low

1031780

S35A4
Probable UDP-sugar transporter protein SLC35A4

1

0

High-throughput

0.268

Low

1031785

VKOR1
Vitamin K epoxide reductase complex subunit 1

1

0

High-throughput

0.268

Low

1031790

TACAN
Ion channel TACAN

1

0

High-throughput

0.268

Low

394659

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.261

Low

147417

SOCS3
Suppressor of cytokine signaling 3

1

0

High-throughput

0.251

Low

148000

C56D2
Transmembrane reductase CYB561D2

1

0

High-throughput

0.251

Low

213118

SNG1
Synaptogyrin-1

1

0

High-throughput

0.251

Low

318481

CDS2
Phosphatidate cytidylyltransferase 2

1

0

High-throughput

0.251

Low

623619

IBP5
Insulin-like growth factor-binding protein 5

1

0

High-throughput

0.251

Low

674147

HMOX2
Heme oxygenase 2

1

0

High-throughput

0.251

Low

1031786

YIPF4
Protein YIPF4

1

0

High-throughput

0.251

Low

1031789

TM147
BOS complex subunit TMEM147

1

0

High-throughput

0.251

Low

1031793

CXL16
C-X-C motif chemokine 16

1

0

High-throughput

0.251

Low

1031796

AT131
Endoplasmic reticulum transmembrane helix translocase

1

0

High-throughput

0.251

Low

1031808

LCAP
Leucyl-cystinyl aminopeptidase

1

0

High-throughput

0.251

Low

1031813

PEX16
Peroxisomal membrane protein PEX16

1

0

High-throughput

0.251

Low

886067

RHBL3
Rhomboid-related protein 3

1

0

Small-scale

0.249

Low

1031766

ASB17
Ankyrin repeat and SOCS box protein 17

1

0

Small-scale

0.249

Low

1031771

CUL5
Cullin-5

1

0

Small-scale

0.249

Low

1031776

ANKR9
Ankyrin repeat domain-containing protein 9

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024