Protein: DPM1
Dolichol-phosphate mannosyltransferase subunit 1 (EC 2.4.1.83) (Dolichol-phosphate mannose synthase subunit 1) (DPM synthase subunit 1) (Dolichyl-phosphate beta-D-mannosyltransferase subunit 1) (Mannose-P-dolichol synthase subunit 1) (MPD synthase subunit 1)

Gene: DPM1
Organism: Homo sapiens
Interactions: 182
UniProt ID: O60762

Gene Ontology (top 5):
GO:0004169 - dolichyl-phosphate-mannose-protein mannosyltransferase activity
GO:0004582 - dolichyl-phosphate beta-D-mannosyltransferase activity
GO:0005537 - D-mannose binding
GO:0005634 - nucleus
GO:0005783 - endoplasmic reticulum

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

255624

ILK
Scaffold protein ILK

3

1

High-throughput

0.667

High

255703

DPM3
Dolichol-phosphate mannosyltransferase subunit 3

4

0

Small-scale

0.661

High

255553

MYC
Myc proto-oncogene protein

3

2

High-throughput

0.650

High

255666

FBXW7
F-box/WD repeat-containing protein 7

3

3

Small-scale

0.640

High

255554

RAF1
RAF proto-oncogene serine/threonine-protein kinase

3

2

High-throughput

0.633

High

255592

T23O
Tryptophan 2,3-dioxygenase

2

0

High-throughput

0.626

High

255653

TBA1A
Tubulin alpha-1A chain

2

3

High-throughput

0.588

High

131610

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

2

1

Small-scale

0.584

High

240240

PRKN
E3 ubiquitin-protein ligase parkin

2

2

High-throughput

0.584

High

255655

HUWE1
E3 ubiquitin-protein ligase HUWE1

2

1

High-throughput

0.584

High

255670

AURKB
Aurora kinase B

2

1

High-throughput

0.584

High

255563

CFTR
Cystic fibrosis transmembrane conductance regulator

2

0

High-throughput

0.576

High

255586

KPCI
Protein kinase C iota type

2

1

High-throughput

0.571

High

255621

MK07
Mitogen-activated protein kinase 7

2

1

High-throughput

0.571

High

255627

CUL3
Cullin-3

2

0

High-throughput

0.559

High

255562

ARAF
Serine/threonine-protein kinase A-Raf

2

2

High-throughput

0.558

High

255568

ELK1
ETS domain-containing protein Elk-1

2

0

High-throughput

0.547

High

255569

NFKB1
Nuclear factor NF-kappa-B p105 subunit

2

0

High-throughput

0.547

High

255578

BMI1
Polycomb complex protein BMI-1

2

0

High-throughput

0.547

High

255593

PAXI
Paxillin

2

0

High-throughput

0.547

High

255560

IGF1R
Insulin-like growth factor 1 receptor

1

7

High-throughput

0.536

High

255572

TBG1
Tubulin gamma-1 chain

1

3

High-throughput

0.536

High

255596

TMEDA
Transmembrane emp24 domain-containing protein 10

1

6

High-throughput

0.536

High

255651

LMTK1
Serine/threonine-protein kinase LMTK1

1

9

High-throughput

0.536

High

255685

UN93B
Protein unc-93 homolog B1

1

1

High-throughput

0.536

High

255556

NTRK1
High affinity nerve growth factor receptor

2

5

High-throughput

0.533

High

255620

PAK1
Serine/threonine-protein kinase PAK 1

2

1

High-throughput

0.521

High

255677

M3K14
Mitogen-activated protein kinase kinase kinase 14

2

3

High-throughput

0.521

High

255614

ZBT16
Zinc finger and BTB domain-containing protein 16

1

0

High-throughput

0.518

High

255690

BRF2
Transcription factor IIIB 50 kDa subunit

1

1

High-throughput

0.515

High

255647

Q6FHY5
MEOX2 protein

1

1

High-throughput

0.515

High

129620

CBX4
E3 SUMO-protein ligase CBX4

1

0

High-throughput

0.513

High

255616

BST2
Bone marrow stromal antigen 2

1

0

High-throughput

0.513

High

255626

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

1

0

High-throughput

0.513

High

255628

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

0

High-throughput

0.513

High

255682

B2L14
Apoptosis facilitator Bcl-2-like protein 14

1

0

High-throughput

0.513

High

255608

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

2

High-throughput

0.501

High

255581

BASI
Basigin

1

0

High-throughput

0.493

High

255636

P2RY6
P2Y purinoceptor 6

1

2

High-throughput

0.489

High

255649

MDEAS
Mitotic deacetylase-associated SANT domain protein

1

1

High-throughput

0.489

High

255597

MEOX2
Homeobox protein MOX-2

1

1

High-throughput

0.481

High

255679

KLF16
Krueppel-like factor 16

1

0

High-throughput

0.479

High

255544

TP4A3
Protein tyrosine phosphatase type IVA 3

1

3

High-throughput

0.479

High

255547

RECQ4
ATP-dependent DNA helicase Q4

1

2

High-throughput

0.479

High

255550

BRD1
Bromodomain-containing protein 1

1

1

High-throughput

0.479

High

255551

LATS1
Serine/threonine-protein kinase LATS1

1

1

High-throughput

0.479

High

255552

EGFR
Epidermal growth factor receptor

1

1

High-throughput

0.479

High

255555

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

255561

ROS1
Proto-oncogene tyrosine-protein kinase ROS

1

6

High-throughput

0.479

High

255565

RFA2
Replication protein A 32 kDa subunit

1

3

High-throughput

0.479

High

255570

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

1

High-throughput

0.479

High

255571

FGFR3
Fibroblast growth factor receptor 3

1

7

High-throughput

0.479

High

255575

ARNT
Aryl hydrocarbon receptor nuclear translocator

1

1

High-throughput

0.479

High

255576

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.479

High

255582

VGFR3
Vascular endothelial growth factor receptor 3

1

10

High-throughput

0.479

High

255583

FLT3
Receptor-type tyrosine-protein kinase FLT3

1

10

High-throughput

0.479

High

255589

RECQ1
ATP-dependent DNA helicase Q1

1

1

High-throughput

0.479

High

255590

YAP1
Transcriptional coactivator YAP1

1

3

High-throughput

0.479

High

255591

SOX2
Transcription factor SOX-2

1

1

High-throughput

0.479

High

255599

RAB9A
Ras-related protein Rab-9A

1

1

High-throughput

0.479

High

255602

PLK1
Serine/threonine-protein kinase PLK1

1

3

High-throughput

0.479

High

255609

CDC42
Cell division control protein 42 homolog

1

5

High-throughput

0.479

High

255610

RHOA
Transforming protein RhoA

1

3

High-throughput

0.479

High

255612

H4
Histone H4

1

1

High-throughput

0.479

High

255615

EP300
Histone acetyltransferase p300

1

2

High-throughput

0.479

High

255622

TIF1B
Transcription intermediary factor 1-beta

1

1

High-throughput

0.479

High

255625

BIRC3
Baculoviral IAP repeat-containing protein 3

1

1

High-throughput

0.479

High

255634

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

1

High-throughput

0.479

High

255635

KIF14
Kinesin-like protein KIF14

1

1

High-throughput

0.479

High

255638

T22D1
TSC22 domain family protein 1

1

3

High-throughput

0.479

High

255640

HIF1A
Hypoxia-inducible factor 1-alpha

1

1

High-throughput

0.479

High

255646

VIR
Protein virilizer homolog

1

1

High-throughput

0.479

High

255650

LMBRL
Protein LMBR1L

1

5

High-throughput

0.479

High

255654

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.479

High

255657

GOLI
E3 ubiquitin-protein ligase RNF130

1

3

High-throughput

0.479

High

255661

FBX22
F-box only protein 22

1

1

High-throughput

0.479

High

255662

RBCC1
RB1-inducible coiled-coil protein 1

1

4

High-throughput

0.479

High

255664

ESR2
Estrogen receptor beta

1

4

High-throughput

0.479

High

255674

PHF12
PHD finger protein 12

1

1

High-throughput

0.479

High

255675

CIC
Protein capicua homolog

1

3

High-throughput

0.479

High

255678

GRWD1
Glutamate-rich WD repeat-containing protein 1

1

1

High-throughput

0.479

High

255680

ACE2
Angiotensin-converting enzyme 2

1

1

High-throughput

0.479

High

255683

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

1

3

High-throughput

0.479

High

255691

RC3H2
Roquin-2

1

3

High-throughput

0.479

High

255693

BRD7
Bromodomain-containing protein 7

1

2

High-throughput

0.479

High

255705

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.479

High

255706

TES
Testin

1

1

High-throughput

0.479

High

255707

HECD1
E3 ubiquitin-protein ligase HECTD1

1

1

High-throughput

0.479

High

255708

FZR1
Fizzy-related protein homolog

1

3

High-throughput

0.479

High

255710

CHIP
E3 ubiquitin-protein ligase CHIP

1

3

Small-scale

0.479

High

255713

MAGD1
Melanoma-associated antigen D1

1

1

High-throughput

0.479

High

255548

DPM2
Dolichol phosphate-mannose biosynthesis regulatory protein

1

0

Small-scale

0.464

High

128658

MEN1
Menin

1

0

High-throughput

0.458

High

156751

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.458

High

179766

BET1
BET1 homolog

1

0

High-throughput

0.458

High

255549

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

255557

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

0

High-throughput

0.458

High

255566

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

0

Small-scale

0.458

High

255579

PHB1
Prohibitin 1

1

0

High-throughput

0.458

High

255584

SYUA
Alpha-synuclein

1

0

High-throughput

0.458

High

255585

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

255587

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

0

High-throughput

0.458

High

255595

MCM2
DNA replication licensing factor MCM2

1

0

High-throughput

0.458

High

255598

CDK7
Cyclin-dependent kinase 7

1

0

High-throughput

0.458

High

255601

IMA1
Importin subunit alpha-1

1

0

High-throughput

0.458

High

255603

ATX3
Ataxin-3

1

0

High-throughput

0.458

High

255604

FOXA1
Hepatocyte nuclear factor 3-alpha

1

0

High-throughput

0.458

High

255611

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

255613

HSF1
Heat shock factor protein 1

1

0

High-throughput

0.458

High

255617

TFCP2
Alpha-globin transcription factor CP2

1

0

High-throughput

0.458

High

255623

CLN3
Battenin

1

0

Small-scale

0.458

High

255629

TRI14
Tripartite motif-containing protein 14

1

0

High-throughput

0.458

High

255632

HAPR1
HUWE1-associated protein modifying stress responses 1

1

0

High-throughput

0.458

High

255648

PRP8
Pre-mRNA-processing-splicing factor 8

1

0

High-throughput

0.458

High

255663

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

255671

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

255672

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.458

High

255684

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.458

High

255689

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

255696

TOM22
Mitochondrial import receptor subunit TOM22 homolog

1

0

High-throughput

0.458

High

255698

AKIP
Small ribosomal subunit protein mS38

1

0

High-throughput

0.458

High

255701

WWOX
WW domain-containing oxidoreductase

1

0

High-throughput

0.458

High

255702

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

0

High-throughput

0.458

High

255704

HDAC6
Protein deacetylase HDAC6

1

0

High-throughput

0.458

High

255558

A4
Amyloid-beta precursor protein

1

2

Small-scale

0.445

High

255605

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

5

High-throughput

0.445

High

255631

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

2

High-throughput

0.445

High

138419

BIN1
Myc box-dependent-interacting protein 1

1

0

High-throughput

0.438

High

217593

TGON2
Trans-Golgi network integral membrane protein 2

1

9

High-throughput

0.437

High

255545

CD123
Translation initiation factor eIF2 assembly protein

1

5

High-throughput

0.437

High

255546

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

3

High-throughput

0.437

High

255567

VGFR1
Vascular endothelial growth factor receptor 1

1

10

High-throughput

0.437

High

255573

TNR6
Tumor necrosis factor receptor superfamily member 6

1

1

High-throughput

0.437

High

255574

CATS
Cathepsin S

1

2

High-throughput

0.437

High

255577

UFO
Tyrosine-protein kinase receptor UFO

1

4

High-throughput

0.437

High

255580

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

255594

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

1

High-throughput

0.437

High

255600

RND2
Rho-related GTP-binding protein RhoN

1

4

High-throughput

0.437

High

255607

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

1

High-throughput

0.437

High

255618

MERTK
Tyrosine-protein kinase Mer

1

5

High-throughput

0.437

High

255633

TNIP1
TNFAIP3-interacting protein 1

1

2

High-throughput

0.437

High

255637

RHOH
Rho-related GTP-binding protein RhoH

1

5

High-throughput

0.437

High

255639

NTRK3
NT-3 growth factor receptor

1

5

High-throughput

0.437

High

255642

DDR2
Discoidin domain-containing receptor 2

1

5

High-throughput

0.437

High

255643

ANR55
Ankyrin repeat domain-containing protein 55

1

2

High-throughput

0.437

High

255645

A16L1
Autophagy-related protein 16-1

1

3

High-throughput

0.437

High

255652

TRI67
Tripartite motif-containing protein 67

1

8

High-throughput

0.437

High

255656

ZCH18
Zinc finger CCCH domain-containing protein 18

1

2

High-throughput

0.437

High

255665

TNR14
Tumor necrosis factor receptor superfamily member 14

1

1

High-throughput

0.437

High

255667

MFRN2
Mitoferrin-2

1

4

High-throughput

0.437

High

255686

Q9H4D1
Receptor-interacting serine/threonine-protein kinase 4

1

1

High-throughput

0.437

High

255687

RHOJ
Rho-related GTP-binding protein RhoJ

1

4

High-throughput

0.437

High

255688

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.437

High

255692

RHOF
Rho-related GTP-binding protein RhoF

1

4

High-throughput

0.437

High

255695

FBX6
F-box only protein 6

1

2

High-throughput

0.437

High

255699

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

5

High-throughput

0.437

High

255709

ALK
ALK tyrosine kinase receptor

1

5

High-throughput

0.437

High

255559

JUN
Transcription factor Jun

1

0

High-throughput

0.426

High

255588

CNDD3
Condensin-2 complex subunit D3

1

0

High-throughput

0.426

High

255700

SPHK1
Sphingosine kinase 1

1

0

Small-scale

0.426

High

255606

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

1

High-throughput

0.407

High

255714

X6RFA8
Solute carrier family 25 member 28

1

2

High-throughput

0.407

High

193161

SOCS1
Suppressor of cytokine signaling 1

2

0

High-throughput

0.298

High

255619

TIAM1
Rho guanine nucleotide exchange factor TIAM1

1

0

High-throughput

0.282

High

166590

BCKD
Branched-chain alpha-ketoacid dehydrogenase kinase

1

0

High-throughput

0.279

Low

104924

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

255564

GBRA1
Gamma-aminobutyric acid receptor subunit alpha-1

1

0

High-throughput

0.249

Low

255630

GRM2
Metabotropic glutamate receptor 2

1

0

High-throughput

0.249

Low

255641

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

0

High-throughput

0.249

Low

255644

OTU1
Ubiquitin thioesterase OTU1

1

0

High-throughput

0.249

Low

255658

SKA3
Spindle and kinetochore-associated protein 3

1

0

Small-scale

0.249

Low

255659

ASXL1
Polycomb group protein ASXL1

1

0

High-throughput

0.249

Low

255660

FBXL6
F-box/LRR-repeat protein 6

1

0

High-throughput

0.249

Low

255668

CLUA1
Clusterin-associated protein 1

1

0

High-throughput

0.249

Low

255669

PP14B
Protein phosphatase 1 regulatory subunit 14B

1

0

Small-scale

0.249

Low

255673

BROMI
Protein broad-minded

1

0

Small-scale

0.249

Low

255676

RUFY1
RUN and FYVE domain-containing protein 1

1

0

High-throughput

0.249

Low

255681

HOIL1
RanBP-type and C3HC4-type zinc finger-containing protein 1

1

0

High-throughput

0.249

Low

255694

ANLN
Anillin

1

0

High-throughput

0.249

Low

255697

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

0

High-throughput

0.249

Low

255711

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low

255712

PHLA3
Pleckstrin homology-like domain family A member 3

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025