Protein: PNO1
Pre-rRNA-processing protein PNO1 (Partner of NOB1) (Ribosomal RNA-processing protein 20)

Gene: PNO1
Organism: Saccharomyces cerevisiae S288C
Interactions: 107
UniProt ID: Q99216

Gene Ontology (top 5):
GO:0000056 - ribosomal small subunit export from nucleus
GO:0000447 - endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 - endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0005634 - nucleus
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

820415

RIO2
Serine/threonine-protein kinase RIO2

13

3

Small-scale

0.757

High

798370

ENP1
Essential nuclear protein 1

11

1

Small-scale

0.754

High

1064096

NOB1
20S-pre-rRNA D-site endonuclease NOB1

7

2

Small-scale

0.739

High

442203

RS14A
Small ribosomal subunit protein uS11A

2

1

Small-scale

0.737

High

1059266

TSR1
Ribosome biogenesis protein TSR1

6

2

Small-scale

0.729

High

677651

KRR1
KRR1 small subunit processome component

2

0

High-throughput

0.716

High

678498

PWP2
Periodic tryptophan protein 2

4

1

Small-scale

0.697

High

1055545

NOC4
Nucleolar complex protein 4

6

0

Small-scale

0.690

High

1084593

RIO1
Serine/threonine-protein kinase RIO1

4

3

Small-scale

0.676

High

1046113

DHR1
Probable ATP-dependent RNA helicase DHR1

5

0

Small-scale

0.672

High

1046838

UTP14
U3 small nucleolar RNA-associated protein 14

3

2

High-throughput

0.661

High

1039887

UTP17
NET1-associated nuclear protein 1

3

3

High-throughput

0.656

High

836223

DIM1
Dimethyladenosine transferase

4

0

Small-scale

0.644

High

918870

UTP22
U3 small nucleolar RNA-associated protein 22

3

0

High-throughput

0.634

High

756707

LTV1
Protein LTV1

4

0

Small-scale

0.631

High

918626

SLX9
Ribosome biogenesis protein SLX9

3

0

Small-scale

0.623

High

753678

RS3A1
Small ribosomal subunit protein eS1A

1

1

High-throughput

0.618

High

1065635

KEL3
Kelch repeat-containing protein 3

2

0

High-throughput

0.587

High

806608

UTP9
U3 small nucleolar RNA-associated protein 9

2

0

High-throughput

0.585

High

823421

UTP18
U3 small nucleolar RNA-associated protein 18

2

0

High-throughput

0.585

High

826238

FAF1
Protein FAF1

2

0

Small-scale

0.585

High

1056509

UTP4
U3 small nucleolar RNA-associated protein 4

2

1

Small-scale

0.584

High

1085005

NOP58
Nucleolar protein 58

2

1

High-throughput

0.584

High

924675

NAT10
RNA cytidine acetyltransferase

2

0

High-throughput

0.559

High

1084435

RRP6
Exosome complex exonuclease RRP6

2

0

Small-scale

0.559

High

1085064

RRP12
Ribosomal RNA-processing protein 12

2

0

Small-scale

0.559

High

722398

XPO1
Exportin-1

1

1

High-throughput

0.536

High

1043329

HAS1
ATP-dependent RNA helicase HAS1

1

0

High-throughput

0.513

High

792340

GBLP
Small ribosomal subunit protein RACK1

1

1

High-throughput

0.479

High

1045141

UTP5
U3 small nucleolar RNA-associated protein 5

1

1

High-throughput

0.479

High

1053145

UTP13
U3 small nucleolar RNA-associated protein 13

1

3

High-throughput

0.479

High

1053548

UTP21
U3 small nucleolar RNA-associated protein 21

1

2

High-throughput

0.479

High

1065611

BMS1
Ribosome biogenesis protein BMS1

1

2

High-throughput

0.479

High

1084635

UTP12
U3 small nucleolar RNA-associated protein 12

1

2

High-throughput

0.479

High

1084950

NOP56
Nucleolar protein 56

1

1

High-throughput

0.479

High

1085019

CMR1
DNA damage-binding protein CMR1

1

1

High-throughput

0.479

High

150039

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.458

High

435475

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

512741

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.458

High

513307

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.458

High

594666

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

647261

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

0

High-throughput

0.458

High

671295

SIS1
Protein SIS1

1

0

High-throughput

0.458

High

673263

RRP7
Ribosomal RNA-processing protein 7

1

0

High-throughput

0.458

High

674924

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

708676

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

735251

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

747672

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.458

High

754366

DCA13
Protein SOF1

1

0

High-throughput

0.458

High

758436

UTP11
U3 small nucleolar RNA-associated protein 11

1

0

High-throughput

0.458

High

763662

UTP20
U3 small nucleolar RNA-associated protein 20

1

0

High-throughput

0.458

High

802473

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

804982

LRP1
Exosome complex protein LRP1

1

0

High-throughput

0.458

High

817667

UTP7
U3 small nucleolar RNA-associated protein 7

1

0

High-throughput

0.458

High

825106

RRT14
Regulator of rDNA transcription protein 14

1

0

High-throughput

0.458

High

844687

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.458

High

852635

ROK1
ATP-dependent RNA helicase ROK1

1

0

High-throughput

0.458

High

864566

MTR4
ATP-dependent RNA helicase DOB1

1

0

High-throughput

0.458

High

865205

MPP10
U3 small nucleolar RNA-associated protein MPP10

1

0

High-throughput

0.458

High

871086

NOL10
Ribosome biogenesis protein ENP2

1

0

High-throughput

0.458

High

874619

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

918918

RRP46
Exosome complex component RRP46

1

0

Small-scale

0.458

High

919209

UTP8
U3 small nucleolar RNA-associated protein 8

1

0

High-throughput

0.458

High

923279

ESF2
Pre-rRNA-processing protein ESF2

1

0

High-throughput

0.458

High

924010

CSL4
Exosome complex component CSL4

1

0

High-throughput

0.458

High

924882

NOP15
Ribosome biogenesis protein 15

1

0

High-throughput

0.458

High

925181

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.458

High

925229

IMP4
U3 small nucleolar ribonucleoprotein protein IMP4

1

0

High-throughput

0.458

High

963826

H3
Histone H3

1

0

High-throughput

0.458

High

1033659

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

1036442

UTP6
U3 small nucleolar RNA-associated protein 6

1

0

High-throughput

0.458

High

1044180

GIS1
Transcriptional activator/repressor GIS1

1

0

High-throughput

0.458

High

1046287

UTP15
U3 small nucleolar RNA-associated protein 15

1

0

High-throughput

0.458

High

1050226

RRP5
rRNA biogenesis protein RRP5

1

0

High-throughput

0.458

High

1051185

FCF1
rRNA-processing protein FCF1

1

0

High-throughput

0.458

High

1051734

RRP45
Exosome complex component RRP45

1

0

Small-scale

0.458

High

1054033

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

1054567

NEP1
Ribosomal RNA small subunit methyltransferase NEP1

1

0

High-throughput

0.458

High

1054888

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.458

High

1055458

RRP9
Ribosomal RNA-processing protein 9

1

0

High-throughput

0.458

High

1056340

BFR2
Protein BFR2

1

0

High-throughput

0.458

High

1061657

RCL1
rRNA processing protein RCL1

1

0

High-throughput

0.458

High

1064322

SGO1
Shugoshin

1

0

High-throughput

0.458

High

1064342

UTP16
U3 small nucleolar RNA-associated protein 16

1

0

High-throughput

0.458

High

1084171

FCF2
rRNA-processing protein FCF2

1

0

High-throughput

0.458

High

1084366

SAS10
Something about silencing protein 10

1

0

High-throughput

0.458

High

1084478

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

1084868

DBP10
ATP-dependent RNA helicase DBP10

1

0

High-throughput

0.458

High

1185388

EFG1P
rRNA-processing protein EFG1

1

0

High-throughput

0.458

High

1403971

NOP14
Nucleolar complex protein 14

1

0

High-throughput

0.458

High

709502

HRR25
Casein kinase I homolog HRR25

1

1

Small-scale

0.445

High

805730

YHS2
MIP18 family protein YHR122W

1

0

High-throughput

0.438

High

512184

RS4A
Small ribosomal subunit protein eS4A

1

0

Small-scale

0.426

High

727446

HS104
Heat shock protein 104

1

0

High-throughput

0.426

High

782514

RPF2
Ribosome biogenesis protein RPF2

1

0

High-throughput

0.426

High

820253

SSB2
Ribosome-associated molecular chaperone SSB2

1

0

High-throughput

0.426

High

1030629

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

0

High-throughput

0.426

High

503329

RS22A
Small ribosomal subunit protein uS8A

2

0

High-throughput

0.305

High

1055176

CORO
Coronin-like protein

1

0

High-throughput

0.269

Low

383977

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

410424

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.249

Low

455347

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.249

Low

795300

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

812815

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

918514

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.249

Low

1064851

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.249

Low

1038012

NU116
Nucleoporin NUP116/NSP116

1

0

Small-scale

0.232

Low


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Last updated: 11Aug2025