Protein: APC7
Anaphase-promoting complex subunit 7 (APC7) (Cyclosome subunit 7)

Gene: APC7, ANAPC7
Organism: Homo sapiens
Interactions: 141
UniProt ID: Q9UJX3

Gene Ontology (top 5):
GO:0000792 - heterochromatin
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005680 - anaphase-promoting complex
GO:0005819 - spindle

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

672917

CDC27
Cell division cycle protein 27 homolog

20

18

Small-scale

0.986

High

1017459

CDC20
Cell division cycle protein 20 homolog

12

20

Small-scale

0.971

High

1023016

CDC16
Cell division cycle protein 16 homolog

6

17

High-throughput

0.950

High

1288136

APC16
Anaphase-promoting complex subunit 16

5

5

Small-scale

0.919

High

1356109

CDC23
Cell division cycle protein 23 homolog

4

18

High-throughput

0.900

High

1356137

FZR1
Fizzy-related protein homolog

4

20

Small-scale

0.866

High

887627

APC15
Anaphase-promoting complex subunit 15

3

6

Small-scale

0.847

High

1310884

APC13
Anaphase-promoting complex subunit 13

3

5

High-throughput

0.839

High

1356134

APC4
Anaphase-promoting complex subunit 4

11

11

Small-scale

0.754

High

236988

BUB1B
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta

7

17

Small-scale

0.741

High

804365

NOTC1
Neurogenic locus notch homolog protein 1

1

4

High-throughput

0.691

High

1356135

ANC2
Anaphase-promoting complex subunit 2

3

20

Small-scale

0.656

High

1246278

CDC26
Anaphase-promoting complex subunit CDC26

3

6

High-throughput

0.650

High

175291

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

17

High-throughput

0.647

High

851366

NEK2
Serine/threonine-protein kinase Nek2

3

11

Small-scale

0.633

High

1356133

APC5
Anaphase-promoting complex subunit 5

3

12

Small-scale

0.633

High

890884

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

2

2

Small-scale

0.629

High

1270827

CBP
CREB-binding protein

2

15

Small-scale

0.624

High

1356136

FBX5
F-box only protein 5

2

7

Small-scale

0.624

High

1328552

APC1
Anaphase-promoting complex subunit 1

3

11

Small-scale

0.624

High

295372

RECQ4
ATP-dependent DNA helicase Q4

1

8

High-throughput

0.618

High

903589

WDR5
WD repeat-containing protein 5

1

7

Small-scale

0.618

High

1219389

CUL9
Cullin-9

1

6

Small-scale

0.618

High

1334042

WDR76
WD repeat-containing protein 76

1

9

High-throughput

0.618

High

861971

PLK1
Serine/threonine-protein kinase PLK1

2

9

High-throughput

0.611

High

1267233

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

2

3

High-throughput

0.601

High

1332587

MAGIX
PDZ domain-containing protein MAGIX

3

6

High-throughput

0.599

High

476539

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

2

5

High-throughput

0.595

High

229015

PRKN
E3 ubiquitin-protein ligase parkin

2

16

High-throughput

0.584

High

918108

H4
Histone H4

2

4

High-throughput

0.584

High

1029346

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

2

8

Small-scale

0.584

High

1057017

MDC1
Mediator of DNA damage checkpoint protein 1

2

15

Small-scale

0.584

High

1198286

UBP37
Ubiquitin carboxyl-terminal hydrolase 37

2

6

Small-scale

0.584

High

1354791

ZRAN1
Ubiquitin thioesterase ZRANB1

2

5

High-throughput

0.584

High

1356132

APC7
Anaphase-promoting complex subunit 7

1

19

Small-scale

0.575

High

370667

ESR1
Estrogen receptor

2

14

High-throughput

0.571

High

1328973

CDT1
DNA replication factor Cdt1

1

1

Small-scale

0.561

High

1161482

CP087
UPF0547 protein C16orf87

2

4

High-throughput

0.558

High

388787

HSPB1
Heat shock protein beta-1

1

3

High-throughput

0.541

High

208951

FOXS1
Forkhead box protein S1

1

3

High-throughput

0.536

High

426754

H10
Histone H1.0

1

2

High-throughput

0.536

High

455982

PARP1
Poly [ADP-ribose] polymerase 1

1

4

High-throughput

0.536

High

507302

LAMP1
Lysosome-associated membrane glycoprotein 1

1

2

High-throughput

0.536

High

565064

HMGA1
High mobility group protein HMG-I/HMG-Y

1

1

High-throughput

0.536

High

818582

SOX2
Transcription factor SOX-2

1

4

High-throughput

0.536

High

1029997

TIF1B
Transcription intermediary factor 1-beta

1

13

High-throughput

0.536

High

1061284

NUMA1
Nuclear mitotic apparatus protein 1

1

3

High-throughput

0.536

High

1069558

TEBP
Prostaglandin E synthase 3

1

1

High-throughput

0.536

High

1087467

H2B2E
Histone H2B type 2-E

1

5

High-throughput

0.536

High

1272683

CSN5
COP9 signalosome complex subunit 5

1

2

High-throughput

0.536

High

1292280

AURKB
Aurora kinase B

1

6

High-throughput

0.536

High

1303836

CDC5L
Cell division cycle 5-like protein

1

4

High-throughput

0.536

High

1318660

FOXQ1
Forkhead box protein Q1

1

2

High-throughput

0.536

High

1328697

NUCKS
Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1

1

1

High-throughput

0.536

High

771089

TCPZ
T-complex protein 1 subunit zeta

1

4

High-throughput

0.515

High

1271784

TANK
TRAF family member-associated NF-kappa-B activator

1

0

High-throughput

0.513

High

1086939

UBE2S
Ubiquitin-conjugating enzyme E2 S

1

4

Small-scale

0.501

High

1350224

CFA97
Cilia- and flagella-associated protein 97

1

3

High-throughput

0.489

High

149403

CTRO
Citron Rho-interacting kinase

1

3

High-throughput

0.479

High

160839

AURKA
Aurora kinase A

1

6

High-throughput

0.479

High

163437

XPO1
Exportin-1

1

10

High-throughput

0.479

High

165733

SET1A
Histone-lysine N-methyltransferase SETD1A

1

9

High-throughput

0.479

High

245070

BRD4
Bromodomain-containing protein 4

1

11

High-throughput

0.479

High

245757

B4GT2
Beta-1,4-galactosyltransferase 2

1

2

High-throughput

0.479

High

262617

TULP3
Tubby-related protein 3

1

1

High-throughput

0.479

High

275236

GRAP2
GRB2-related adapter protein 2

1

12

High-throughput

0.479

High

277372

ST1C4
Sulfotransferase 1C4

1

1

High-throughput

0.479

High

311777

ATG7
Ubiquitin-like modifier-activating enzyme ATG7

1

3

High-throughput

0.479

High

319370

BRD1
Bromodomain-containing protein 1

1

6

High-throughput

0.479

High

323277

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

7

High-throughput

0.479

High

362310

GLPA
Glycophorin-A

1

1

High-throughput

0.479

High

391959

H2A1B
Histone H2A type 1-B/E

1

3

High-throughput

0.479

High

453689

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

8

High-throughput

0.479

High

554012

RFA2
Replication protein A 32 kDa subunit

1

6

High-throughput

0.479

High

652556

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

High-throughput

0.479

High

656331

PSA5
Proteasome subunit alpha type-5

1

4

Small-scale

0.479

High

669055

PML
Protein PML

1

13

High-throughput

0.479

High

673303

WEE1
Wee1-like protein kinase

1

11

High-throughput

0.479

High

707784

H2B1B
Histone H2B type 1-B

1

5

High-throughput

0.479

High

721733

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.479

High

780291

CCNF
Cyclin-F

1

12

High-throughput

0.479

High

799033

GATA4
Transcription factor GATA-4

1

5

High-throughput

0.479

High

875411

TERA
Transitional endoplasmic reticulum ATPase

1

2

High-throughput

0.479

High

931035

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

7

Small-scale

0.479

High

935353

H31
Histone H3.1

1

6

High-throughput

0.479

High

952688

H33
Histone H3.3

1

6

High-throughput

0.479

High

963697

E2F1
Transcription factor E2F1

1

1

Small-scale

0.479

High

975480

PPARD
Peroxisome proliferator-activated receptor delta

1

8

High-throughput

0.479

High

996132

HDHD1
Pseudouridine-5'-phosphatase

1

1

High-throughput

0.479

High

999188

EP300
Histone acetyltransferase p300

1

20

Small-scale

0.479

High

1019165

TP53B
TP53-binding protein 1

1

9

High-throughput

0.479

High

1035626

SMAD4
Mothers against decapentaplegic homolog 4

1

5

High-throughput

0.479

High

1036188

BIRC3
Baculoviral IAP repeat-containing protein 3

1

3

High-throughput

0.479

High

1042800

CUL3
Cullin-3

1

4

High-throughput

0.479

High

1067183

BRD3
Bromodomain-containing protein 3

1

12

High-throughput

0.479

High

1088117

UPP1
Uridine phosphorylase 1

1

1

High-throughput

0.479

High

1128378

SOLH1
Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1

1

1

High-throughput

0.479

High

1173268

PAXI1
PAX-interacting protein 1

1

9

High-throughput

0.479

High

1189008

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

2

High-throughput

0.479

High

1236560

SIR6
NAD-dependent protein deacylase sirtuin-6

1

3

Small-scale

0.479

High

1242686

TNR6A
Trinucleotide repeat-containing gene 6A protein

1

11

Small-scale

0.479

High

1269882

ESR2
Estrogen receptor beta

1

14

High-throughput

0.479

High

1284841

EFMT3
EEF1A lysine methyltransferase 3

1

4

High-throughput

0.479

High

1285217

SH3K1
SH3 domain-containing kinase-binding protein 1

1

11

High-throughput

0.479

High

1304832

TBX5
T-box transcription factor TBX5

1

2

High-throughput

0.479

High

1306174

NPAS1
Neuronal PAS domain-containing protein 1

1

2

High-throughput

0.479

High

1328294

CCDC8
Coiled-coil domain-containing protein 8

1

3

High-throughput

0.479

High

1331255

SMRCD
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1

1

7

High-throughput

0.479

High

1332129

CIA2A
Cytosolic iron-sulfur assembly component 2A

1

1

High-throughput

0.479

High

1332744

EGLN3
Prolyl hydroxylase EGLN3

1

2

High-throughput

0.479

High

1342829

BRD7
Bromodomain-containing protein 7

1

14

High-throughput

0.479

High

1343367

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

1

High-throughput

0.479

High

1344964

LATS2
Serine/threonine-protein kinase LATS2

1

3

Small-scale

0.479

High

1348897

TLS1
Splicing factor C9orf78

1

2

High-throughput

0.479

High

1356138

TRI33
E3 ubiquitin-protein ligase TRIM33

1

16

Small-scale

0.479

High

1356139

PHF8
Histone lysine demethylase PHF8

1

6

Small-scale

0.479

High

1356140

TRRAP
Transformation/transcription domain-associated protein

1

1

High-throughput

0.479

High

1014238

MN1
Transcriptional activator MN1

1

0

Small-scale

0.458

High

1115764

CRY2
Cryptochrome-2

1

0

High-throughput

0.458

High

1148859

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

1302782

RUFY1
RUN and FYVE domain-containing protein 1

1

0

High-throughput

0.458

High

989174

FMR1
Fragile X messenger ribonucleoprotein 1

1

1

High-throughput

0.457

High

1044247

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

6

High-throughput

0.445

High

1057707

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

3

High-throughput

0.445

High

1031113

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

2

High-throughput

0.437

High

1100171

INF2
Inverted formin-2

1

5

High-throughput

0.437

High

1114456

AMZ1
Archaemetzincin-1

1

1

High-throughput

0.437

High

1172191

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.437

High

1232983

D2HDH
D-2-hydroxyglutarate dehydrogenase, mitochondrial

1

3

High-throughput

0.437

High

1254599

PKHO2
Pleckstrin homology domain-containing family O member 2

1

2

High-throughput

0.437

High

1308840

ZFY21
Zinc finger FYVE domain-containing protein 21

1

2

Small-scale

0.437

High

1331581

PKHA4
Pleckstrin homology domain-containing family A member 4

1

9

High-throughput

0.437

High

1349238

MTCH1
Mitochondrial carrier homolog 1

1

4

High-throughput

0.437

High

1354127

CCG4
Voltage-dependent calcium channel gamma-4 subunit

1

1

High-throughput

0.437

High

1356141

GPR45
Probable G-protein coupled receptor 45

1

1

High-throughput

0.437

High

831778

CEBPA
CCAAT/enhancer-binding protein alpha

1

4

High-throughput

0.408

High

723268

PE2R4
Prostaglandin E2 receptor EP4 subtype

1

0

High-throughput

0.282

High

1297491

IMP1L
Mitochondrial inner membrane protease subunit 1

1

0

High-throughput

0.279

Low

536454

GLU2B
Glucosidase 2 subunit beta

1

0

High-throughput

0.249

Low

1116261

MINY4
Probable ubiquitin carboxyl-terminal hydrolase MINDY-4

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024